Shoreditch is a lovely neighborhood - especially if you appreciate authentic food from all around the world - and it was quite easy to get to most places in London we wanted to go. There is a lot to do in the area, but as with any popular spot, it's not particularly quiet (especially on weekends); sirens and voices from the street drift up to the flat loud and clear throughout the night. The flat is quite sunny (when the sun decides to shine in London, that is), which is lovely, unless you're trying to sleep in on the pull-out couch -- there are no curtains or blinds in that room, and it gets extremely bright!
Be careful around the bathroom - it's right off of the staircase, and is a step up both into the bathroom and into the shower - my mother and I both tripped a couple of times in the beginning before we became accustomed to it.
Overall, a very positive experience! John and his team certainly know what they are doing, and the accommodations were perfectly adequate and in a great location.