We had a fantastic time at Can & Mert's hotel. Villa Galley has been fully renovated so our room was modern and clean with a great bathroom. Guests have access to the fully equipped kitchen, and we made breakfast here each day (supermarkets, bakeries and fruit stalls are only 2 minutes from the hotel).
The neighbourhood is very quiet and is mostly surrounded by houses, not annoying touristy restaurants. There are some great cheap local eateries nearby so you don't have to always go into Sultanahmet for dinner.
Mert gave us excellent advice on how to see the city, and all the historic sites are within walking distance from the hotel. We were very lucky that he was able to show us parts of Istanbul that we would never have had a chance to see otherwise.
Can & Mert made us feel very much at home. You won't find another place as special as this anywhere else in Istanbul.