This is the best location in the very center - one can go down the street and end up at the boat stations or go up the street and come to Taxim and then want further and get to Nisantasi, one of my favorite parts of Istanbul. All walkable (not with a big stroller or for elderly people). Keep in mind that central location brings with it a lot of noise. Plus there was construction and a mosque is right in front of the windows.
The hosts are great and very accommodating. The place, I would say, needs a bit more done to it - the little things that make life comfortable are missing - like towel hooks in the bathrooms and hand towels.
Another issue - no ventilation in the rooms, so we had to open the windows all the time and because of the noise we had to choose between sleeping and breathing, kids didn’t sleep. We didn’t sleep. So that I would say is the biggest issue, hence 4 stars, otherwise a wonderful experience