Missy's place is ideally located near the famous Istakelal street. The place is only a 3 mins walk from Istakelal/Sishane metro station on one side and 7 mins walk from the Tophane tram station on another. Despite being very close to a very happening area, the house is quiet and we were able to sleep really peacefully during our stay.
There are plenty of grocery stores nearby and almost unlimited food options on Istakelal. There is also a vegan restaurant close by which serves a really good hummus plate.
The house itself is perfect. A few stairs to the elevator, cooking amenities are sufficient, washing/drying facilities are complete. The house is very clean with a great bathroom and ample storage space.
The host is very gracious and was waiting for us when we arrived. She showed us around the apartment and even later communication was very easy. She also booked a cab for us back to the airport which was really helpful.
Small points to consider though we had no problem:
The apartment is a steep uphill from Tophane and a few stairs to the elevator. Also the bed is on the smaller side for a couple.