I have stayed at a few Airbnbs in Istanbul and this is a good find. It is right opposite the tram stop which can take you to Sultanahmet (blue mosque, bazaar etc) and a quick walk to the funicular that connects you to the Metro and Taksim square. It's also within walking distance to Galataport and Karakoy for restaurants and bars. Also, a quick walk to Kabatas ferry port if you want to visit the Princes Islands. Just note, you are at the bottom of a big hill so if you want to walk up to Istiklal st it can be a trek. But you can always take the funicular which is nice.
The apartment itself is in a new building and has all the things you need. There is an elevator which can be a rare find in Istanbul apartment buildings. I was working remotely and the internet was great to do this. I also asked to borrow an office chair which made things easier. There are some nice coffee shops nearby also like Antidote and Jupiter Coffee.
The host was really helpful and answered any queries that I had. I would definitely recommend it.