Perfect for my needs as a solo traveler, Eray & Lee's place is conveniently located in Cehangir (with a lot of terrific cafes nearby), and a 15-20 minute walk from Eminonu and Sulatanahmet (historical districts) as well as Besiktas (for more nightlife options). Also a short distance from the bus and tram lines.
Eray and Lee are very hospitable; I felt very at-home during my adventures in Istanbul :)