The guest house is in a great location. From the Suvarnabhumi airport, it takes about 40 min by taxi to get to the guesthouse. It may be a little tricky if you do not have the exact address. I suggest keeping the phone number of the host and getting the exact address to provide to the taxi driver.
The guest house is about a 5 min walk from Phra Arthit Pier. So we could check out pretty much all major attractions of Bangkok (Wat Pho/Arun/Grand palace etc) using the orange flag boat for ticket price 15B per person (watch out for people upselling to buy the 40B ticket for tourist boat).
The guest house is also about 10-15 mins from Khao San Road and away from frenzy of Khaosan. We could hang out in Khao San until late in the night and walk back to the guesthouse.
We are vegetarians, so we used to dine in vegan places on Khaosan. But if you diet is more flexible, there are some street food places right outside the guesthouse and also on Phra Sumen (near the Phra Arthit Pier).
The host was also very helpful with lot of useful information because it was our first time in Bangkok/Thailand. They also accommodated us (for an extra fee) because our flight arrived in Bangkok at 7:30am and the checkin time was 2-3pm.
Overall, its great value if you have a family and want some privacy and a quite place.