I'm hesitant to say too many nice things because it will be booked next time I want to come!
My flight arrived at 1 am but that was not a problem. I typed "s bloc" into the cab driver's phone and we were on our way. The fare from the airport was less than 400 baht. Keypad and keycard were set up for easy access.
The neighborhood is great. There are many office buildings on Rama IV so you will see workers coming through for lunch, getting street food or eating at nearby restaurants. The throngs of workers are a testament to the good food and services nearby. Nightlife on Silom is a lot of fun.
Some reviews here are outdated. The sushi restaurant is currently closed; no outsiders use the first floor. Most of your interactions will be thru AirBNB because the "front desk" isn't often staffed ... these are pluses; I had a lot of privacy. Someone said the Internet seems to cut out occasionally. It was barely noticeable. Depends on your software ... Netflix wasn't affected.