The Nest is located somewhat far from the city so if you are looking to go to standard Bangkok attractions (floating market, Grand Palace, some of their larger parks) it is a bit far. However, Ekemai and Sukhumvit are two neighborhoods nearby that offer shopping and dining experiences. We spent a lot of our time in these neighborhoods and found some fun places to eat - Moola serves ice cream in a homey-style shop & there are also many coffee shops nearby.
The actual Airbnb is serene in comparison to the city and definitely offered us an oasis to come home to at night. One thing I was a bit surprised by is the room itself - we were upgraded since it was our honeymoon, but the room decor/style was a little bland (main colors were gray and white) in comparison to the rest of the space.
Still, we enjoyed it & our hosts were extremely helpful! Even though they probably have people ask them directions all the time, they helped guide us without hesitation. They also encouraged us to take the red bus that locals do (which we did) so that was fun!