If you want an authentic local Thai area then this is it. I stayed in Supandas gem of a B&B five nights and didn't see another foreigner here in that time.
A little out of the way but plenty of taxis, tuk tuks and buses with the pier only about 20 minutes walk away, boat being a lovely way to travel.
Supanda is a wonderful host who absolutely goes out of her way for you. Her breakfasts are great, she makes a killer coffee in her very cozy coffee shop below the rooms and she is continually recommending things to do and see. She even has an organic hair salon on the premises too.
The place is newly renovated so everything is fresh and clean. It's a buzzing area with some good little restaurants, a great massage place with the owner and her husband both accomplished artists having a gallery on the top floor.
You will do well to make your stay in Bangkok here with Supanda.