Mama's Garden is a little slice of paradise! The house itself is beautifully decorated and very comfortable, and the garden is wonderful.
The Thonburi area is on the west bank of the Chao Phraya and is wonderful. It's quieter than on the east bank, more relaxed, has less tourists and locals are invariably friendly. Like many places in Bangkok, the streets are a sort of open air kitchen/restaurant crammed with delicious delights.
There are some nice sights to see in Thonburi (Wat Arun, the canals, markets, ...) and the other districts are easily accessed by cross-river ferry (at Khlongsan market, just a short walk), Skytrain, meter taxi or tuk-tuk.
Our host was amazing, she fulfilled our every wish so we are already looking forward to staying at this lovely place again.