This is my new go-to place whenever I come to Zurich. The place is secure, is a very short walk to public transport, and central to a lot of places. Kitchenette is well stocked and there is plenty of closet/shelving space. Dayana was quick to respond to my questions at check-in, and the flat is definitely a safe place for single traveling women.
(PS For long-haired folks, the water pressure is also amazing)