I'm not sure that it's possible to find a better place to stay in the heart of Zurich. Maria's place is spacious by Zurich standards, in a comfortable neighborhood with plenty of cafes and restaurants and parks within a few blocks. Two bedrooms, a huge kitchen, a cute little patio, and lots of nice Chilean and Swiss touches throughout. Considering how pricey Zurich is, Maria's place was mind-blowingly inexpensive.
There's a tram right outside the door that can take you wherever, but we barely used it -- Zurich is compact, and you can walk anywhere. The 10-minute walk from the train station is uphill, so if you have a lot of luggage, you might prefer a cab, but it's a great stroll without baggage. :)
I can't recommend this place enough! Just do it.