This was a fantastic apartment located very centrally in Madrid. On arrival, it was only a short 5 minute walk from the Madrid Airport Express Shuttle Bus stop at Plaza de Cibeles (the 2nd last stop - 5 Euros each from the airport). But with Madrid being quite compact and the apartment being so central, you could really walk to just about anywhere you wanted to go. But if walking is not your go, it is 2 minutes from the Gran Via and the metro station there. The red tourist bus route also goes right down Gran Via.
Luis was waiting for us to give us an orientation and he had all sorts of local information, much of which he has printed out in the apartment - details of great cafes and restaurants and other sites. The apartment was spotlessly clean and very comfortable and was as described - a very comfy bed, good facilities, lots of extra towels, an oven, microwave, washing machine, iron, etc.
In Calle Reina, there were lots of nice bars and restaurants and the nearby neighbourhood is a mixture of local and some fashionable stores.
All in all, we would stay in Luis's apartment again without hesitation