The Picasso was a great place to stay, the location was about as central as one could be, my sister and I walked or took a taxi everywhere we went and we never walked more than a mile or so to get to all the sights of Barcelona. We plan to come back because two days is not enough, but Damien's list of recommendations is a great place to start. Tapeo tapas restaurant was as amazing as he said it would be and Gaudi's Casa Mila was breathtaking, not to mention La Sagrada Familia is basically next door to the airbnb. I truly enjoyed my stay.