This is a great spot to stay in Santiago! The house is clean, modern, and nice, and it's in a very quiet location. However, it has easy access to the rest of the city and there's a good coffee shop and running trail nearby (my girlfriend and I went for a late night run along the river and it was a beautiful way to see the city; at one point we even had one of the local feral dogs join us on the run for a stretch :-)
Ana Maria was very, very accommodating and a breeze to work with (and her English is very good, if that's important to you). Would definitely recommend staying here while in Santiago.