Patricio's place is a really cool loft space right in the thick of Santiago. It's within walking distance of many site seeing activities, including museums, Castillo Hidalgo, and San Cristóbal Hill.
It's in a safe neighborhood and super close public transit, and overall a great place to stay. His apartment and the roof of the apartment also have great views of the city.
The only note is that while Patricio is really thoughtful in offering transportation to and from the airport, he does charge you (which is totally acceptable). But his price was a little pricey and it ended up being cheaper to simply get a cab.