Brian and Pablo are super responsive, super nice bilingual hosts and their apartment is a fresh remodel just a hop, skip and jump from the Santa Lucia metro stop and within 1-2km of most museums, paseos and parks that you will want to visit. The building is not a luxury building but I thought it was well maintained and the residents were always quite nice to this obvious gringo in my week in Santiago. Just one aviso: San Ysidro does offer quite a bit of ambient noise--since the apartment is on the 10th floor this often felt like white noise, but I still slept with my headphones and white noise app just to make sure (one night there was a rather lively protest on the street below). Blackout curtains in the bedroom and a brita water filter are two little things that I appreciated...and super fast/reliable wi-fi.