This place is a great home base. While most of the restaurants and night life and public transport is across the river (15 minute walk), this is a quiet neighborhood and does have both a market and a pizza parlor across the street that has a full bar. Don't underestimate the value of that food, especially at 10:30 at night when you want to eat or have wine/cocktails. It's your only option and it's a good one.
The photos in the AirBnB ad are gorgeous, detailed, and accurate, but it is a wide angle lens. As such, the rooms are a bit smaller than you might expect, but still plenty of room. The kitchen has a small bar which 2-3 people can eat on comfortably, the master bedroom is LARGE with a desk, the bathroom is comfortable with okay water pressure (high in the spray setting) and a towel heater. There are great details that are thoughtfully and tastefully done and just about everything is updated. WiFi is reliable and excellent and SOMETIMES even reaches the pizza place across the street for access to the menu via QR code!
Heating and cooling has three zones: living, master, and second bedroom.
The second bedroom is, well, small. It's big enough for a twin bed and not much else, maybe 10'x7'. We had an adult staying in that room, but it's probably best for a child.
The kitchen is STOCKED. While it doesn't have an oven, it has a toaster oven, microwave, dishwasher, fridge, and everything you'd need in a kitchen. Want to zest a lemon? No problem. Need tinfoil to heat pizza in that toaster oven? They provide it. Wine opener, cutting boards, oven mitts, coffee and coffee maker, etc, etc, etc.
No promises for you, but they provided a 1.5 liter of water and a bottle of 2020 wine -- really appreciated.
We walked daily to the Costanera building, used a BIP card from Los Leones or Pedro de Valdivia to anywhere for very low cost (pro tip: you only need one for multiple people).
It's 15-20 min from the airport via taxi.