Marco and his family were wonderful hosts! We arrived late, at 10p, and they had waited up for us to give us a rundown of the space. They were so kind and fun :)
The room is located in a housee that has a few separate individual rooms kind of like a hostel, but with private bathrooms. We chose this location because it was close to the airport and we were only staying for one night to wait for a connecting flight to Patagonia. The location is residential and a bit further from Santiago, so I would just keep that in mind (about 25 min).
Clean, simple, safe (cameras outside the home as well as monitoring the entrance). Would definitely recommend this spot for a quick layover in Santiago!