I cannot recommend this place for many reasons. It is an incredibly hot apartment (in summer). The temperatures (which I measured with an electronic thermometer) stayed very high even at night when it was cool outside. This is partly because the apartment gets sunshine most of the day (it faces north). It was really uncomfortable inside on many days. Obviously I kept the windows open, but it was sweltering. I'm sure it is cozy in winter.
With the windows open you get exposed to a lot of noise. The area is semi industrial and there are always a lot of noise, dust and flies during the day. At night dogs bark for hours and loud parties are held, even on some weeknights. The building security did nothing to stop this.
There is only a real curtain for half of the window area so you get woken up really early when the sun rises - so sleeping there was bad. Speaking of which, the bed has got a protector on the mattress which is so thick and plasticky that it feels like sleeping on plastic - really uncomfortable. I have seen protectors on many airbnb beds and they were fine, but this one made the bed feel awful to sleep on.
When I got into the apartment I encountered a full list of the contents of the apartment (in Spanish) and a message that I will be charged through airbnb for any damage. Whereas this is obviously the right of any airbnb place (and it we all know that one is responsible for damage) to put such papers up, I have never encountered this in any of the more than 20 airbnb places that I have stayed in in the last few years. It leaves a bad taste in the mouth. And if the place was stocked with bone china or crystal, one could maybe still get it. But the place was stocked with old, cheap and chipped plates, bowls and cups in very limited numbers.
Lastly, I know my way around Santiago including the area in which it is located. However, ask anybody and you will be told that Estacion Central is a really dangerous area. This, together with the fact that it is a bit far from the metro and bus stops to walk to the building, I would definitely not recommend it for overseas tourists. It would be very risky for you to walk the streets in this area at night and even sometimes at day if you are a tourist.