The house is a bit away from the centre of town but this is exactly the way we like it - a bit away from the noisy centre. It offered us all the conveniences of home for a family of 5. Each of the kids got their own room and we had ours.. An extra toilet made rush hour a bit more manageable.
The house is lovely and spacious with all the amenities one needs and a fully functional kitchen. Joao was a very helpful host and was able to respond very quickly whenever the need arose ( I think twice on the first day).
The walk into the centre takes about 20 mins, something we would prefer to do, teenagers allowing. There is a metro station right outside the house and about 3 pastelarias within 5 mins walking distance. Location wise I can't think of a better place from which to explore Porto.