Ana's house is a cozy place aside from overcrowded streets hidden in the picturesque district of Vila Nova de Gaia. Everything is in the vicinity: the Porto downtown is in 15 min walk through the famous Dom Luís I Bridge; wine cellars and lively embankment (with a great coffee bar!) are spread just down the hill; suburban beaches are available by train (10-15 min) and the station is in 5 min walk (the metro station too!). This place is in a dense neighborhood of small townhouses, so if you plan to enjoy late homemade dinners in the small patio as we did, do it respecting the neighbors! Still, loud and bright nightlife activities are just a few metro stations away, and the metro operates 24 hours during the weekend, so you could easily return home this way.
Overall, it is a nice place to explore Porto from all angles -- and both river banks!