We stayed for 6 nights. last week. The location in the center was excellent. We walked everywhere. We absolutely loved the neighborhood. There’s a great grocery just a 6 minute walk away. Rembrandt’s house and Amsterdam’s Hermitage are nearby! We quickly oriented ourselves for exploring the city.
I am mobile but also use a wheelchair. The ground level of the airbnb was ideal. There’s one short step to the closet/toilet/shower/bathroom sink if that is an issue for you.
We had to access an Uber or taxi when we left. We did have difficulty finding an Uber due to road closures in the area. We walked to a hotel we had passed several times during the week and asked a concierge about Uber accessibility and also where a taxi stand could be found. He was as frustrated as we were. The car service he had ordered the day before was encountering road closures and was late. He pointed the way to a taxi stand. There we found a delightful driver. He had us at our destination promptly. You may want to give yourself extra time to work this out.