An interesting place to stay in an interesting neighborhood. This is a commercial building that is rehabbed to become a hotel. Enter the place via a mystery door with no sign. Two shops that share the front of the building. After hours the shops close, and the entrance can become hard to find. I recommend taking a photo of the entrance to make it easier to locate.
This place is about a 10-15 minute walk from the Zocalo. Many options for coffee and dining are available within that walking radius. The hotel has nothing- no lobby, no restaurant. Keep that in mind.
BUT the neighborhood has numerous museums to explore. The historical synagog is across the street and down a few steps.