I highly recommend staying at Juan and Patty's place! They were amazing hosts - super easy to reach, they made check-in and check-out very easy, and they even welcomed us with some very thoughtful snacks, since we were arriving late in the evening and restaurants were already closed.
The apartment is spacious, cute, clean, and in a very safe area. We were able to walk throughout Polanco very easily. We'll definitely be back the next time we stay in Mexico City!