Our first week in Mexico City was awful, and then we came here and everything changed for the better. It has really been great staying in this place. The kids refer to this place as home. This location is close to everything. You won't need a car. There is a great bakery (Saint) two blocks away, a fantastic restaurant (Ciene) at the end of the block, tons of great restaurant within a ten minute walk, and multiple tiendas around for whatever you need.
The host was super responsive and available. The hot water kettle went out and we had a new one within an hour. This is a great (and super clean) place to stay for exploring Mexico City.