Most people who are not truly familiar with the area or culture, will tell you that the area is in a bad neighborhood. However, I have never had a problem staying in Mexico City. As in any city, don't walk around drawing unnecessary attention, wearing gaudy jewelry in public and stand out as a target.
I was in town for business and left early and returned late. Not really walking around the neighborhood for any reason expect to eat some tacos at the several vendors located down the street.
The building is secure and has a doorman 24hrs.