If you are traveling - esp with more than one person - Leslie & Alex’s place is THE BEST.
It’s a bit far from Condesa / Roma, but Polanco is super gorgeous and walkable (not NYC-walkable, but you can get around on foot easily).
About 200m down the road is a super fancy grocery store and there are TONS of high-end malls within a 10-min walk in case you need to pick up something from a Sanborn’s.
The Soumaya Museum is RIGHT THERE and you’re also right by Parco Lineal, a running / biking path that leads you straight to Chapultepec Park. So this place is GREAT FOR RUNNERS.
There’s also a gym and pool but I didn’t try those.
Walking distance to Pres. Masaryk (CDMX’s 5th Ave), lots of hip bars, PUJOL, and the famous hole-in-the-wall taco stand El Turix!
Safety: SO MANY people milling about at night, walking to and from work. It’s like Midtown Manhattan.