The place is wonderful, the host is a great guy and anytime when you want something (tips, advises, small appliances) or anything else needed in the house, he will help.
The place is located in Senglea and it is perfect for tourist which like to visit the old City and would like to have a quiet vacation, in a private, cosy and quiet place.
The villa has also an upper deck which is awesome!!!.. especially in the morning when it is not so hot outside and you can drink a cup of coffee while watching the cruise ships coming in-N-out of the port.
There is a bus station close by (BUS 1) which can take you to Valleta 18 Bus Station and you can get a bus from there to any direction.
If you come by car, I did not see any parking space around, but if you ask the host I'm very sure that they will help you.
Also you can take a ferry from Senglea to Valleta (it is like a 5min walk). The ticket is 1.5EUR for one-way and 2.80EUR for a round-trip and it includes a free passage to the Barrack's elevator (after 2 days you'll be glad that you don't have to climb those steep streets :-) ).
Restaurants are close by, most of them serve in-house made burgers, but you can also find some pasta, fresh fish or rabbit (Maltese traditional dish).
There are many small grocery shops around, but they usually close around 19:00m.
Downside of the location is that if you want to go to a beach or to Popeye's Village, with public transport it will take up to 2h.
Overall, me and my friends enjoyed the place, quite neighborhood, views and of course.. the upper deck which is a good place to chillax. :) You can even get a tan there, without going to the beach. If you're a good swimmer you can take a dive from one of the peers next to the villa.