My wife and I stayed in Alison’s “Renovated 16th Century House in Valletta” for three nights in May 2017. We liked the place, very cool (to us at least) staying in a centuries old home. Alison was communicative and accommodating about us checking in early. Good value for money, I would recommend it.
Just a heads up, when we told our cab driver at the airport where we were going he did not know where Saint Anne’s Street / Triq Sant’ Anna was (in case you are thinking he was trying to scam us, note that the fare from the airport is a posted, fixed, flat rate). You might do better telling your driver it is on the corner of Triq L-Ifran (or Old Bakery Street, Google maps gave us the English street names, and although our driver seemed unfamiliar with Old Bakery, but knew Triq L-Ifran). Old Bakery/Triq L-Ifran runs for most of the length of Valletta though, and it meets Saint Anne almost at the very end of the street. The building is on the corner of Saint Anne’s and Old Bakery, first door on the left as you go down the steps.
It is not in the center of Valletta, but because the city is so small (that is not a criticism, it is a charming city) that really does not matter. We did not have the issue a previous person mentioned about hot water—we followed the instructions and turned the water heater on before showering. I found the water pressure a little low, but it is an old building and that was not a major problem.