This is Barrio Alto, it is always going to be loud and proud. We specifically booked this for the nightlife so were not disappointed.
Pedro and Patricia we great, very responsive and Patricia showed us around the flat on arrival.
The place is up 4 flights so you need to be pretty mobile however that does also get you out of the immediate noise of the street, there is a little balcony.
There is some construction going on just down the street but we didn't notice it at all.
So all in all a great place to stay for the street life in a fabulous city, very central and easy to walk or tram to the subway.