Jesse's apartment is lovely, very nice design and even though you might have to do four floors of stairs the view from the living room is totally worth it.
The location is strategic, I've been moving around by foot 'cause everything was really close, but you can easily take the metro that is just 2 min by walk or the bus which has a stop just outside the door.
Jesse has been a great host, really present even if he was away for work and caring checking on me if I needed anything.
Definitely the place to stay while in Lisbon, if you are looking for a cozy and central place.