Absolutely amazing place run by even better hosts. The place overlooks a small court-yard near the local church. Kids play on the streets and there are tourists casually walking through. It also near the main road which connects to central for 2-3 euros in an uber and you get to enjoy the BEAUTY of alfama with just a few steps. Go tile hunting, or enjoy the view, or do anything your heart desires as it's all nearby, safe and magical. The place itself is simply perfect, really relaxing, has character and amenities and it will make you feel great your whole trip.
Alfama is built with stairs on the hill, so the area itself is not the best for wheel-chair access or people with leg injuries - i'd recommend barrio for that.
Our group comprised of 3 guys and we loved it. Absolutely amazing place to stay while you're in Lisbon!