My wife and I had a very pleasant experience when we stayed at Yukiko & Maki's house. The location is relatively close to city center and it's Yukiko's house is very close to Senjuohashi Station that can easily access big stations in Tokyo.
From Haneda Airport, luckily there were an airport limousine bus that made stop at Senjuohashi station. This made my trip very convenient because we can avoid Tokyo's train system that is not convenient for taking 2 big suitcases (30') and 2 carry-on :)
Yukiko and Maki were a helpful host and understand our situation that always leave early and coming home very late. Even though there is a baby, we hardly hear the baby's cry. The neighborhood is very quiet but convenient. Definitely will stay again at Yukiko & Maki's house when visiting Tokyo in the future.