Isa and Yumi's place is a gem. It operate like a cozy hostel, with several guests staying at one time. The common and private spaces are immaculately clean and the hosts are kind and welcoming. Yumi prepares homemade soup every morning for guests and ample snacks are available (including coffee!). Isa readily offers directions or suggestions for things to do nearby and how to get to locations/experiences further away. Check-in is easy due to Isa's accommodating schedule and check-out was a breeze due to a convenient key drop policy.
In terms of location, the hostel is in a peaceful residential neighborhood in eastern Tokyo. There are some fun place to eat nearby, including a very highly rated ramen shop. Although the immediate neighborhood is fairly calm, it is walking distance to Sensō-ji shrine in Asakusa and no more than a 30 minute train trip to neighborhoods and fun stuff to do in West Tokyo (Shibuya, Shinjuku, Meiji Shrine). The hostel is especially convenient for travelers coming from Haneda airport as it only takes one train to travel between the two locations.
I cannot overemphasize how wonderful our experience was - staying with Isa and Yumi was the right call.