We booked last minute, the hosts were very responsive and gave us detailed instructions on how to get to the property which can be tricky in Venice. A private water taxi from the airport (even though expensive) gets you right in front of the property. If you have kids, the courtyard garden is a big bonus (ask for room 10 to access directly). Ludovica helped us tremendously with precise directions and guidance during a time in the city when aqua Alta set in (important if you are traveling in October). She also helped get us a provte water taxi to the train station well in advance.
They also set up a crib which was very convenient with a toddler. The location is great as it is easily accessible to San Marco by foot and yet away from the crowded feeling. Lots of local stores in this hood. Convenient kitchen to prepare small meals for baby.