The perfect location!!! After staying in Venice for 4 nights and walking around most of the island San Polo was our favourite district. It was a mix of locals and some tourists. We loved staying on the square, and even though it is on the ground floor, you would never know it. I can't believe how quiet it was and how secure you feel. Outside of your door you have a place to grab a coffee in the morning and a couple of places to eat. You are in walking distance to a few little grocery stores as well. We ended up not really needing to take the vaporetto (boat) because the location allows you to cross bridges to most of the places you want to see. We were about a 12 min walk from the famous Rialto Bridge and a few minutes more after crossing that you are in the San Marco district. You are about a 12 min walk to take the vaporetto to the small islands if you wan to to do that (we did). So central, and a nice escape from the crowds, which you will want to getaway from after a day exploring.
The apartment was clean and stayed cool so we never even needed to use air conditioning even when hot outside. It was the perfect size for a couple. The shower worked great and bathroom and kitchen were good. I read a couple reviews about the firm mattress. I guess it was a little, but it did not bother me or my partner. We slept really well. So unless you are really picky I would not worry.
Andrea, your host, is so lovely. He emailed us tips and suggestions of where to go. We ate at a few and really enjoyed them. Plus he meets you in person and gives you the tour and your keys.
I highly recommend it as your home base in Venice.