My wife and I cannot recommend Jacopo's apartment highly enough. From the location on the Grand Canal to the furnishings to the extra little details that make one's stay special - everything was superb. Jacopo is an exceptional host. Very welcoming, a font of local knowledge and careful to make sure that guests have everything they need to settle into the apartment. My wife and I stayed in Jacopo's apartment for our 20th Wedding Anniversary and we loved every moment of it.
In practical terms the apartment is 4 minutes walk from the Sant'Angelo waterbus stop - Alilaguna Orange Line stops there from the airport making transfer really easy. The Rialto Bridge is a short walk away. But the apartment is well positioned for you to discover hidden gems off the tourist route where you can rub shoulders with Venetians in local bars and restaurants.
All in all a superb and memorable stay. Can't wait to go back.