I had a wonderful stay at Santa Margherita guesthouse. It's in a really perfect location - very close to everything but very, very quiet at night. It's a nice, younger area with a lot of students. Very clean and comfortable. I loved having kitchen access and a refrigerator in my room so I could splurge on lunches and chicchetti out and eat a light dinner in. It's a small place and can get a little loud in the mornings when there are other guests, but if you're using it as a base to explore and not a place to sleep in late it's perfect!! Maria was really kind and helpful. There was an airport strike the day before I had to leave and she let me have the option of keeping my room in case my flight was cancelled. Great place, great value for Venice!!