Irene's place is great! The location is wonderful, particularly if you are visiting for the Biennale (as we were) - it is close to the Arsenale and the Giardini, but not so far east that getting to the centre is a hike. It's only a 15/20 minute walk to the Rialto area, for instance. It's also very close to the Arsenale airport water bus stop, which is nice with bags.
The apartment itself is great. Everything was very clean. There were many towels and a lot of kitchen equipment. One bedroom is ensuite and there is another bathroom upstairs. The showers had good water pressure and were hot. We were two friends travelling together but I think the place would suit two couples very well. There is a private entrance from the street. We had a chilly night and the apartment was warm; the aircon also worked well when it was hot. The street noise is minimal and does not interfere with sleep.
Irene was lovely and communicative. Our flight into Venice was rerouted because of a thunderstorm and we got in much, much later than we had planned (past midnight). Irene came out to let us into the apartment despite the time, and was friendly and helpful, which was really nice of her. Everything was as advertised, and she replied promptly and helpfully to messages.