A great host makes for a great stay. Marco is a great host. He grew up in Venice and he is generous with information and insights. He met us at the water taxi and walked us to his place. When my son had serious stomach pain late at night he came to the rescue. My son turned out to have appendicitis. I hate to think what might have happened without Marco.
The location could not be better. You are a short walk from the Academia Bridge and Vaparetto stop, which is key. The neighborhood has a local flavor unlike the areas nearer to San Marco, which feel a bit too touristy. There are many good restaurants and sites nearby - Academia, Peggy G, Ca Rezonico, and Friari, for example.
The house is not fancy but very nice. My wife, two adult children and I stayed here comfortably for several days. Having two bathrooms is key and the space is large for Italy. Marco provides everything you need to cook, etc. Everything works.
I have stayed at many Air BnBs around the world. You will not regret booking Casa Isabella.