Overall, a great experience (with one exception, explained below). The location is central, making most of Venice accessible within 30 min walking, and the airport water taxi is less than 5 min away. The space itself is charming, comfortable, and air conditioned. We even had access to a balcony overlooking Campo Santo Stefano (the neighboring square), which was a pleasant surprise. Check-in, check-out, and all other communication was seamless.
The exception: there was a fresh stain on one of the bed sheets which made it seem as the though they had not been washed. Our host claimed it was "impossible" the sheets weren't washed, but did end up waiving the tourist tax portion of our dues (about $15). It doesn't look like other guests have had any similar issues, so this is probably a unique case. Still, felt it should be mentioned.