Apartment in a great location about six to ten minutes from the train station, Piazzale Roma and basically all water bus stations. It is on a major thoroughfare that leads to the train station, so there is foot traffic all day long and it is super easy to find, which is not usually the case in Venice. Some noise did filter up to the front bedroom but wasn't a problem in getting a sound sleep. It was actually fun to look down from the balcony at the passerby and people thronging in the nearby plaza with a huge church.
Very close to the Jewish ghetto, so we got to explore the area and sample authentic Kosher food. We also enjoyed the tall ceilings due to the fact that the apartment was on the piano nobile.
Simone is an impeccable host. He was very prompt in his communication and the apartment is supplied with everything you might need. I would suggest reading the Venice guide book he laid out on the coffee table. We only discovered it at the end of our stay so couldn't really take advantage of the information.