This room is outside of Venice but close to public transportation (10 min walk to tram stop, then 25 min tram ride into the main city centre). If you only have 2-3 days to explore Venice, I wouldn't choose this spot because travel time does add up and you'll find that getting around Venice already takes quite a bit of effort. That being said, the neighbourhood of Mestre is convenient, quiet, and residential.
Tommaso's house was beautiful and modern with a very clean, spacious bedroom plus private bathroom and full use of the kitchen. We were even able to use the washing machine which was really great. Although our host was kind, overall I'd say this was just an average stay for us compared to other airbnbs as the place didn't have many of the thoughtful touches for travellers that others do-- there were no bath/toiletry products, no coffee & tea, and minimal interaction with the host although we were living alongside each other. I want to say it was due to a language barrier, but our host couldn't even help us with directions to the airport by public transit although he is local and services travellers.
Couple important things to know to make sure this is the right spot for you:
1) You need to be comfortable with stairs as they are made from marble and don't have much traction
2) You need to be mobile enough to crouch or lie down in a bathtub to wash using a showerhead as there isn't a curtain
3) You need to be okay with quite a few mosquitos in the night as they do get in the room despite any spray that is being used and I got bitten on my hands and face.
If you're fine with all that, then I'd say this is a great, simple stay with all the amenities you'll need!