We stayed Venice many times, with accommodation in different parts of the city. This was probably the best experience we've had. The apartment is spacious and bright, with windows and views in three directions. The advertisement says the house has three bedtooms but it actually has four. There are six beds: four singles and two doubles. It has four air-conditioning units: in the central hall, in the living room and in two of the bedrooms. It was extremely hot and humid during our stay but we were cool and very comfortable inside. The only small issues we had is that there is no microwave oven and no kettle. Also two of the bedrooms have no shutters or curtains, so the morning light will wake you up if you don't prepare something yourself. We used garbage bags and tape to blind out one bedroom, but for the fourth bedroom it's more complicated because the windows are so large.
The apartment is along a quiet canal, with little boat and pedestrian traffic. Yet the busy canals with lots of pubs and restaurants are just minutes away. There's a large supermarket (Conad) at 2 minutes, and another much nicer one (Spar) at 5 minutes. The train station and Piazzale Roma can be easily reached by foot, but when carrying luggage I would recommend using S. Alvise boat stop (lines 4.2 and 5.2 from the train station or Piazzale Roma) or Guglie boat stop (direct and fast connection to/from the airport with the Orange/Arancio line).