Cristina's Casa Zanchi really is a gem of Venice. If you are lucky enough to stay then you will find yourself within easy walking distance of pretty much all of the tourist landmarks you would like to see, but far enough away from hotspots that you can get a feel for the local side of the city. Cristina herself is a wonderful host who is well prepared with recommendations for lesser-known places of interest and restaurants nearby. The flat is up a few flights if stairs but it is most definitely worth it