We had a lovey stay at this penthouse apartment in Venice. It was very convenient to Piazzale Roma, which is where the People Mover (monorail) dropped us after our cruise.
If you are 6ft or taller, you may want to consider staying elsewhere. 3 of the 4 of us are quite tall and found ourselves ducking the low ceilings of the stairs and apartment constantly. Also be warned that the two bedrooms become one bedroom if you want to use the air conditioner (because you'll have to leave the adjoining door open), which isn't exactly ideal privacy-wise.
But these complaints are truly minor considering the the apartment was meticulously clean, the checkin and out was easy, and the hosts are very communicative. Well worth a visit!