Lucky us--We stayed a month at Casa Palazzo Grassi! If you want the perfect residential neighborhood with a mix of upscale shops, restaurants, and quiet streets, this is it. Casa Grassi is located a half block from a small, less crowded Vaportetta stop, 10 minutes from SanMarco, and less than 10 minutes from the Accademia bridge, and all the conveniences of the Dorsoduro. I feel in love with the small San Samuele campo and deli around the corner.
Antonio and Luisa were excellent hosts, providing us with assistance at check-in and information on how to get to the airport in the middle of the night. They were easy to contact and quick to reply by email and in English.
The house itself is a spacious three floors, with two large bedrooms, two sitting rooms, a bath with shower, a remodeled kitchen, plus the rooftop terrace. Of course, you need to be able to climb stairs, but it would be ideal for two couples, who can share the kitchen or parents with children old enough for stairs. The house is fully equipped for cooking, with a fairly large fridge and brand new wash machine. The Wi-Fi connection was excellent!