Busso’s home gave us a true Venitian aesthetic! It does have stairs so beware of any heavy luggage. I would personally always recommend backpacking as it’s the easiest way to travel through Europe.
The home is very close to local restaurants, a bit away from the central area but easy to get there walking (about 24 minutes) or by water taxi/public transportation (unless they’re on strike). Very quiet neighborhood and extremely grateful for the AC in each of the rooms on a hot summer day.