Giusy's home is very charming with a lot of character. It's located away from tourist attractions, but is close to many nice restuarants and bars. That said, many tourist sites are within only about 20 or 30 minutes walking distance. As a solo female traveller, I felt safe walking back to the house at night.
I didn't get to interact with Giusy much during my stay but she helped me find a way to get to the airport early in the morning when my flight was suddenly changed. This is a great choice for anyone staying in Venice!