Positives: great location, very convenient to transport and more touristy areas like the Accademia and Campo Santa Margherita, but quiet and more residential. Felt much more 'normal' in the best sense. The apartment has a definite aesthetic, with its high ceilings and art all over. Definitely not a beige, IKEA-furniture kind of place!
Negatives: sound insulation not great with floor above, where the hosts live, so you are very aware that your landlord is right above you. Can feel a little oppressive. There was also a strange issue/misunderstanding: a request via private email for an additional tariff in cash for guests staying beyond 2 people. Given it's advertised as a two-bedroom apartment and is set up for 4 to sleep, it didn't seem right to me to be asked to pay more, especially since nowhere in the official Airbnb information about the apartment is there mention of this tariff. So I didn't pay it. Probably best to stick to official communication channel through Airbnb.