We had a really good time in Casa Zanchi! Nico and Nico's mum are always presents to help you to discover Venise.
Casa Zanchi is really well situated, good places to go in the neighbourhood (great restaurant! Nico will tell you!) and some famous historical and artistic sites (Basilica Santa Maria Gloriosa dei Frari, Scuola Grande Di San Rocco) in just a few minutes by foot. Basilica San Marco is less than thirty minutes with the vaporreto.
If you like animated evenings, Campa Santa Margherita is five minutes by foot.
Great!
PS: I forget : delicious breakfast prepared by Nico's mum ;)