Great location, handy for various Vaporetto stops and within walking distance of everything. Easy to get there from airport and main train station, by bus and boat. Not too close to St. Mark's Square, thus pretty quiet on a pleasant little square next to Peggy Guggenheim Museum. Nice little terrace overlooking a green back yard (we didn't use it much in December, though).
Gianfranco and his wife are friendly hosts, as is their son (with whom you mostly communicate beforehand). Speaking and understanding Italian definitely an advantage. Everything went smoothly; you can take #1 or #2 boat from Piazzale de Roma to Accademia stop, or Salute (both boat stops are pretty near).
Rooms, beds, bathrooms and kitchen were all okay; we had everything we needed.
We were very happy and can definitely recommend this accomodation.