Overall this is a nice apartment in an absolutely incredible location. Carlo and Maria Beatrice were very communicative and helpful with ideas and suggestions when we arrived.
A few things to consider. As I'm sure is common with a lot of apartments in Venice, there wasn't a lot of natural light in the living area. The kitchen is also extremely small. The main problem for us, however, was that the second bathroom is on the ground floor (entrance) of the apartment, while both bedrooms are on the top floor. This may not be a problem for most, but because we were traveling as two couples (and the other bathroom is in one of the rooms), it meant a lot of trips up and down two flights of stairs to use the bathroom. Not a massive issue, but this wasn't clear in the description and would have been good to know before booking - at least for our situation. The second bedroom is also realllly small - which you can see in the photos - but again makes things less comfortable if you're traveling as two couples or even a group of friends.
Otherwise the stay was good. The apartment has a lot of charm (wood beamed ceilings, wood floors, etc.), is super central, and the hosts were great.