If you are looking for a best in class stay in Venice you can count on Barbara's one. As a Venetian working abroad I rediscovered the love for my city staying at Barbara's place. Situated in Dorsoduro near Santa Marta you can breathe the true venetian experience and meet the locals living around the neighbourhood away from classical turisty venues.
A note for digital nomads and remote workers: Internet is working like a charm (more than 100mbps in download and upload) also in the internal garden, neighbourhood is really quite and is good for focusing long hours.