Piero and Andreas place is perfectly located in the middle of Venice. The apartment is spacious and good for four people. They have a lift if you need assistance getting up the stairs—very spacious. If you need water taxi, there is a hotel next door that will have access to the canal. Perfect for four people, obviously better if less.
If you need assistance you can always text Piero and Andrea they speak English and are very helpful coordinating. If I could give them more than 5 stars I would! Totally recommend the place!