This is a really nice place to stay. The apartment itself is a third floor walkup, bright and airy, with comfortable beds, and lovely views. It is not in the central part of Venice, but the neighborhood has plenty of restaurants etc, and you can walk to all the major spots in less than 15 minutes. It is only a few steps from two vaparetto (waterbus) stops, so it is easy to reach, and if you get the day passes for the vaporetto, you can hop on and off to get around Venice, which is great when you are tired (or lost) - and then just find one back to either nearby stop. Also, you can connect to Marco Polo airport from those stops as well.
But what really separated it for me was the attention to detail from the hosts. They met us when we arrived, gave us a quick tour, and checked in to make sure we were doing well. A great place to stay.