The apartment is very cosy and well equipped.
Obviously, the commuting time from Mestre to Venice in the morning and at the end of the day is an issue. The bus service is quite efficient, but altogether, including a short walk and the waiting times, you must foresee about half an hour to reach Piazalle Roma and embark on a vaporetto to your final visit destination. Fortunately Piazalle Roma is a convenient hub to reach all Venice locations with many vaporetto lines.
But this is the compromise to have a roomy and cosy apartment at a "reasonable" price.