Mariolina was an excellent host, providing a binder with lots of details for how to navigate Venice, even information about the history of the city and local dishes. She greeted us with pasta and delicious homemade sauce, which we enjoyed since we weren't up for going out after we arrived. Kitchen was well-stocked with snacks, tea, and coffee, and there's some basic toiletries in the bathroom. Mariolina also helped us out by arranging a taxi for our very early morning flight. Thank you Mariolina!
The location is convenient if you don't want to stay on the islands. The apartment is just a quick walk from the train station, and Venice is just a 10 minute bus ride away. Buy a tourist travel pass (which includes the bus and water taxi) at the convenience store up the street, then hop on the bus at the stop a block away. We wanted to be on land to make our early morning flight easier, but I ended up wishing we'd stayed on Venice or one of the islands.
The downside of our stay was that we had a hard time sleeping, as the thin curtains let in a lot of light and you can hear the upstairs neighbor's tv and every footstep.