We loved Lorenzo's home. Was really great for us (2 parents & 2 kids).
Home was immaculately clean, in great condition, everything worked and it was very comfortable.
Lorenzo was the perfect host. He was responsive, gave good advice, was able to supply tickets for the tram (€1.50) and airport bus (€8), and was very attentive and helpful. He lives next door and works around the corner.
The tram stop to get to Venice was 30 seconds walk from the house. It runs around every 10mins and takes 10-15mins (4 stops) to Piazzale Roma.
If you've got luggage and/or you want to keep your Venice accommodation costs down, I highly recommend Mestre - and in particular - Lorenzo's spacious home. We would 100% stay there again.