Wonderful location to stay for a few days. You are in walking distance from all the landmarks in Venice. And because you are 2 streets away from San Marco square, which there are signs for everywhere, you can always easily find your way back. This turned out to be a big plus because Google maps is not very accurate in Venice because of all the super tiny streets.
The AirBNB has more of a hotel-feel to it than the usual accommodation because your room will be cleaned daily. Very nice and unexpired service.
No downsides, would recommend.