Martina's place is amazing. It is perfect for three people. It really did feel like we were home during the days we stayed there. The kitchen was fabulous (we cooked many meals there), the washer was clutch, and everything smelled like flowers. We also had so much space to spread out in. Oh and two words: AIR CONDITIONING!!!!!!!
As for the neighborhood, Murano had everything we needed. There is a large supermarket around the corner, as well as plenty of al fresco drink/dinner options. Probably our favorite surprise about Murano: Skip the people watching, because dog watching is the best! Seriously, everyone has dogs on Murano, and they come in all shapes and sizes.
When it comes to visiting Venice, we preferred to be away from the city center and the crazy tourist crowds. However, that may not be for everyone, so keep that in mind. Luckily, Martina's place is a 1-minute walk (not exaggerating) to the water taxi stop, and it takes 15-20 minutes from there to get anywhere on the main island. We purchased a 7-day unlimited water taxi card for 70 euro, and it was well worth it.