This is a wonderful BNB. It was clean, well stocked with some basic supplies, fresh fruit and very spacious. There is a fully equipped kitchen that we never used because we were only there for 2 days after our cruise.
We were met by an associate of Margherita's that walked us to the room and told us about a nearby restaurant to try. The location is easy to find once you figure out how to get around Venice!!
It is very close to the #1 stop on the water bus system (ACTV) and the A line (Alilaguna) that goes directly to the airport. We took a cruise first so we came from the port but if not we could have come directly from the airport to this bus station. Only one bridge to cross to get to the room. It is up 2 flights of fairly steep stairs so be prepared!
You are 10-15 minutes walking distance to the Rialto Bridge and then another 15 or so to San Marco Square. You can very easily walk to a large number of places to visit. Along the way are a ton of shops and small restaurants.
The room overlooks the intersection of 2 canals and we even had a serenading gondola go through!
All in all, very lovely and we would return again if we go back to Venice!