I love being in the Dorsoduro. The flat was wonderful, quiet and clean. It is quite small however with no real seating area, other than the bed, or a small table, which was in use with our things. Also there is no view from this flat. Despite that, right downstairs are several cafes that look out onto the Guidecca canal. They are perfect for a late afternoon Proseco or Spritz. It's a wonderful spot with so much in the neighborhood to recommend it.
From Marco Polo the Alilaguna Blue Line Water shuttle drops you off at Zattere right in front, very convenient but painfully slow. Beware.