We have enjoyed the appartment very much. It is very close to the Madonna dell'Orto boat stop, which is the first from Marco Polo Airport. So very convenient and only 30 min by boat.
On the map the appartement seems quite far from San Marco etc but as Venice a not that big it is perfect. And the bars and restaurants (2 blocks away) are more authentic and friendly than closer to San Marco or Rialto.
The neighbourhood is called Ghetto but that doesn't associate in anything you might think. It is quiet and peaceful. The only thing your at night is the water floating in the canal.
The appartment is tidy, clean and has everything you need to make your stay comfortable. The little supermarket on 50 mtrs (!) is very handy.