This is a fantastic property. VERY clean, VERY comfortable, well stocked, easy access to the big things in Venice (Rialto, etc), and easy access to wonderful restaurants, a grocery store, and the transportation options in Venice. Irene is an amazing host. From the time that I found her property, through the reservation process, and up to the moment that we boarded a water taxi (that she arranged for us) to depart, she was an integral part of our stay.
We are a family of 6, with 'kids' at 23, 24, 27, and 29, and this was a perfect home away from home for our 4 days in Venice prior to a cruise. We found great restaurants within minutes of walking, the grocery is ~5 minutes, gelato, pharmacy, convenience store, all within 2 minutes.
The property is extremely well cared for. I sent a note to Irene mentioning that a doorknob was loose so that she could repair it before it got worn, and within an hour there was a knock on the door for a repair.
The only word of caution that I would mention are the stairs in to the apartment. There are a LOT of them. As each person arrived they remarked at the number of stairs, but as soon as you discovered the convenience of staying at this location they were just a part of living in Venice. We had 10 days of clothing/luggage each, so getting everything up 3 and a half flights was a chore. But, it's all downhill when it is time to leave. ;)
When we head back to Venice, I do not need to shop for a place to stay. It will be at this same location without hesitation.