We were very happy with our stay in Venice and with Giacomo's place. We were pleased to be in Cannaregio, out of the way of tourists a bit and had some very pleasant day experiences: enjoying the canal right outside your door, walking and seeing residents doing every day things, eating at the local eateries and exploring the Jewish Ghetto and its lovely bakeries... The flat isn't far from "the center of things (for tourists)" (San Marco, etc), about a ten minute walk, so any worry that you might be far from things isn't necessary.
As many reviews have mentioned, the flat is above a noisy restaurant and above a street where a lot of locals and tourists hang out at night until the around 2 or 3am. Most of our stay, my husband and I were up late so this didn't bother us and it was actually very nice to have the nightlife available right outside your door, but I could see this not being welcomed by others who aren't into staying up late... but I would recommend this flat to anyone but also recommend the siesta! ;)
Other things to note: The hosts are lovely people. Everything was clean and tips on the neighborhood were provided. We really appreciated the guidance on the water taxis to the airport as we were a little clueless when we arrived. We got everything sorted easily and had no hiccups.
We miss Venice (and Italy!) already. We had a lovely time and have our Airbnb experiences to thank a lot for that.