This is a very modern house to stay in Venice. The house is well furnished and nicely decorated, very clean and comfortable, on a 2nd floor. Good WiFi and air conditioning. Carlo greeted us at San Samuele boat stop station and explained us the way around Venice from the apartment. It is not far to walk to Rialto, Accademia, San Marco square. We reached the place by private water taxi as we were 7 and with luggages. Otherwise vaporetto line 2 will get you to S. Samuele, check the timetable to make sure of early/late ride.
We will recommend Ca' Dei Zotti to friends/relatives for a stay in Venice!