We had a wonderful time in Venice. Roberto and his sons were very helpful in checking in and giving directions. The apartment is walking distance to St Mark's square and all other sights. It is situated in authentic Venetian house on a top floor and has a terrace where you can have your meals with a view of neighbouring houses and terraces. The apartment is sparkling clean, has modern amenities like temperature control heating, modern shower and kitchen, yet with the original features of a traditional Venetian house preserved. Of course, we got lost multiple times walking to and from the apartment. However, most shopkeepers and waiters were very helpful in giving directions to Fondamente Nuove. The SPA shop is 3-5 minutes walk if you don't get lost. We just followed people with shopping bags or google map directions on a phone (if you have a contract with Virgin be prepared that your internet will not work in Venice).
Venice, at least its historical centre, is like a labyrinth of connecting streets; and unless you live there you have little chance in understanding the maps. For us, it added to its character.
Fondamente Nuove is also a convenient vaporetto stop for airport and direct routes to Murano, Burano and Torcello islands.