I could not recommend this AirBnB higher to anyone visiting Venice. It was so perfect for my husband and me. The room was clean, beautifully decorated and so comfortable. The breakfast was so thoughtfully put together and delicious. There is a grocery store 1 block away.
It was so easy to get into Venice from Mestre - a 5 minute walk to the central station where you can take a tram or a bus right into Venice (~20 minute ride). To get to the hotel orginally, we walked from the Mestre train stop (~25 minute walk but easy to navigate), although there was probably a bus that could have gotten us there. It was also very easy to get to the airport - a (local) bus stop one block away took us there the morning we left.
A tip for Venice - if you are under age 29, you can get a "Rolling Venice" card at the Mestre central information/tourist stop (where the bus/tram station is) which gives you unlimited rides on the trams, buses and water buses for 72 hours, and a discount for some museums. It paid for itself and more even though we were only there for 2 days. Also, any bus ride to the airport is 8 euro a person.