We had a lovely time at Nadia's house! They were very accommodating, allowing us to arrive late in the evening and leave fairly early the next day (8:30am). Nadia is the exact kind of host that AirB&B is hoping for: welcoming, warm and friendly, and offered us a lovely breakfast in the morning. I feel that I have a new friend in Venice!
Assuming you are OK with staying on the mainland side of Venice, the location is very convenient for public transportation, including taking a bus from the airport. It was somewhat complicated identifying the bus stop as the name of the stop was not listed on the airport bus stop sign, so be ready for that if you are taking the bus.
I highly recommend this location and hope to return in the future!