This is a great BnB! Giusy and Allesandro are super nice and friendly and the ample breakfasts really set you up for long days of walking around (getting lost!) in Venice.
There is A/C in the room which was really appreciated in the heat of August, professional maid service cleaned every day and there were lots of fresh towels etc.
A word on the location: it is in a relatively low-tourist-density part of Canarregio, which was great. All the tourist stuff you want to visit is meanwhile easily within distance while you get to retreat to a relatively quiet neighbourhood when you want to get away. For restaurants and bars you are in luck--lots of lively nightlife in little pockets everywhere with great food and drink right in the hood. And oh yeah, the BnB is mere blocks from the Orto vaporetto stop which is the first stop from the airport on the orange line. We didn't realize this when we booked, but it was a huge plus. Likewise getting to the airport it was a quick stroll to the Orto stop and one 30 minute ride to the airport, no other stops. Buying your ticket both ways in advance will cost each person 27 euros total so why bother spending considerably more on a water taxi.
One piece of advice: Venice is SUPER confusing to the novice so before you go look at your routes in and out on Google street view--that way you'll know exactly where you're going.
All in all, would go back to this BnB without hesitation!