I could live here. Venice is a crammed tourist city and I fell in love with this particular the Santa Elena area of the Castello neighborhood. For Venice it is a large apartment and the master room is quite large. There is a second room with a folder out futon if there are more than two on your party.
Luca is an excellent host and gave me a very warm greeting. He provided me with the locations of the neighborhood grocery stores as well as how to best travel around Venice.
The pictures are exactly as what to expect and the apartment is very clean and easy to maintain.
You can take the 5.1 vaporetto directly to the Santa Elena station if you're coming from the bus or rail station. Heading back you can take the 5.2, but Luca suggested catching it at the Giardini station as the 5.2 stops there more frequently.
The neighborhood is very quiet to the rest of Venice. It can almost be too spooky with how quiet it gets - but you'll almost always find people in the park nearby.
I cannot recommend this listing enough. I look forward to coming back here again!