This was my first trip overseas using AirBnB and it was so refreshing to have such great and transparent communications. Francesca & her husband Julian were available when needed, and the description to arrive at the apartment was spot on. There were no communication gaps or language barriers whatsoever.
Everything was clean, and as advertised. The area (Castello) is close enough to all the "action" - conveniently located, 10 mins from San Marco, Arsenale, and the Giardini - but on a quiet street where the only thing you'll really hear are people getting lost realising there is no bridge to cross over the canal. There are also plenty of non-touristy cafes and restaurants to eat at within walking distance (just avoid the Riva along the Grand Canal).
Vaporetto stops (Venice ferry system) are all close by, though you can easily walk everywhere! The map provided by the hosts was extremely helpful to get around the city, however the best thing to do in Venice is let yourself get lost on some back streets; (you really discover the city that way!).
I would gladly stay at this location if I return to Venice, and will be recommending it to friends and family as well.