This place is really close to the bus station or even the train station if you arrive by one of these to Venice. There are several grocery stores close by, my recommendation would be Coop which is just past the bus station, were Vaporeto stops (boats) are. We walked to the bridge Rialto and St. Mark's square several times. There are yellow signs that guide you so you don't have to worry too much about getting lost. Also, on our way back, we just followed signs directing us to Piazalle Roma (the bus station) or Ferrovia (the train station), since the place is so close to both.
The place was great to stay at for three people. The "odd" one gets something like his own room. There were two ACs and even a fan so we were comfortable in a middle of the summer.
Also, Lucia and Andrea communicated really fast and their instructons for self check in were clear and easy to follow.
After all, if you want a comfortable and pretty quiet place in Venice, this is the one. :)