Luca's place was amazing. Very cute and clean, nicely designed, had everything we needed for our weekend trip. It's really central but off on a quiet street away from the hustle and bustle. But the most amazing thing about Luca's place is Luca himself. He came and met us off the boat, gave us lots of great tips (with google maps links) to where to eat and what to see, including little bits of history of Venice - we tried some of his tips and were not disappointed. He is a really friendly guy and responds to everything very quickly - I think he enjoys being a host, and if not he does a very good job of pretending.
Would absolutely recommend and would love to stay again.