Maria Chaira is such a wonderful host... great positive energy, very friendly and very helpful! The Guesthouse itself is in a great location: only about 10 minutes away from the main station, there's a vaporetto just round the corner that takes you straight to the airport and it's walking distance from everything. The room is spotless, the breakfast bountiful and really you have everything that you need.
I don't think you can find a better bargain in Venice. I cannot fault it!