Overall this was a nice place and a great location, it is not in a main touristy area, but it is next to a very cute little square and a short walk from the water bus or to a bridge that goes right into the touristy areas.
The primary issue we had was the lack of air conditioning. There were a few fans, but during the July month especially temperatures are just too hot for a fan to suffice. As a result, we had a tough time sleeping at night and left the windows open but ended up with a lot of bug bites doing that. The place is definitely cute, but if you aren't capable of carrying your bags up two flights of stairs be careful (although we stayed at another place before this and it seems most places in Venice will require that ability). Additionally, the beds in the room with two twins are spring beds and not particularly comfortable spring beds. My husband and I slept on the futon downstairs though which was perfectly comfortable.
The host was nice enough to let us check in early on Saturday which really helped us out, and overall during the cooler months this would definitely be a very nice place to stay.