Irenes house is wonderful and a gold location where you will jave everything you need. It is about a 15 minute walk from the main station, but we recommed not to pack too heavy for Venice in general because its not big luggage friendly. But oce you get into Irenes house, its beautiful. The only thing is there is no ac but luckly there is a nice breeze from the windows. I would recommend Irenes house to anyone. Its nice and overall we had a wonderful experience.