Paolo and this location made our anniversary - and my husband's first time in Venice - special. It's perfect. Palanca to Zattere is just three minutes by vaporetto to get to all the usual tourist sights (plus do visit the Natural History Museum - just marvellous.)
We spent much of Sunday to Thursday this week wandering around Giudecca as well: eating delicious fish at the awesome Palanca (rated 18 out of more than 1,300 places to eat in Venice and frequented by folk staying at the nearby Hilton for exceptional quality and value for money), buying beautiful hand-bound notebooks as gifts at the bookbinders almost next door, or just watching young egrets fly around the bridges. There was plenty of food with fresh fruit and prosecco to welcome us, all the guidebooks and maps you could need and a large comfortable bed. If you come from London in particular, such a peaceful spot is so valuable.
I'd happily have spent hours watching life from the window - hours of cleaning and rubbish disposal by boat go on outside each morning, which is thoroughly entertaining.
I'm already planning a return trip. You won't get a better place to stay or host on here.