Via Toscanella is in the perfect spot, a two minute walk to the Ponte Vecchio and Pitti Palace. Santo Spirito square is around a 3 minute walk and has many places to eat (don't miss a free visit to the basilica to see Michelangelo's crucifix). Claudia at Trattoria Gustapanino is delightful - the wild boar pasta 'orgasmico'! Everything is really close by - the furthest we had to walk was around 15 minutes to the train station (for a day trip to Pisa, which is recommended, catch the train to Pisa San Rossore as it's only a 5 minute walk to the tower, rather than Pisa Centrale). Yes there are 61 steps to the apartment as Luca describes but this was welcome exercise after the many Aperol Spritz and truffle pasta (a must at the Central Market). Check in with Frederica was seamless and she gave us many recommendations for places she likes to eat. Being the other side of the town avoids the crowds and has a more authentic and not so touristy feel. I would fully recommend Luca's apartment