This place could not be more central. It's a 1 minute walk to the Uffizi gallery and close to the Duomo, Santa Croce, Ponte Vecchio etc. but it's in a quiet neighborhood so you don't deal with street noise. It's small but has everything you need for a city trip. Niccolo was there to meet us and showed us how everything worked. He's a friendly guy and encouraged us to contact him with any questions we may have had. Niccolo is also associated with a great wine bar/restaurant called La Prosciutteria round the corner which does great food and wine at good prices. Highly recommend both this place and the restaurant.