Overall this place was a great stay for us simply because it was the exact location we wanted. Hard to be a two-block walk to the Duomo or two block walk to the Academia, and if you continue past the Dumo, a short 5 min walk to the river and basically everything.
Noise? Some but you will always get that in these European cities. This apartment seems to have a minimum of this because the rooms are located in an inner courtyard.
Cleanliness? They need to do a deep scrub of the floors and upgrade the towels. But this is an easy fix and the property owners are such wonderful people who try hard to make the experience pleasant. They make you feel like a welcome guest.
Comfort? Pretty comfortable