I really enjoyed staying in Alessandro's home. It is a special place. Both Alessandro and the house are peaceful, and welcoming. And the resident cat Igor is great company. :-)
The bus is very easy to get to, and the neighborhood is at the bottom of beautiful hills, with a walkable trail along a river. This is a residential neighborhood, so the bus is 15-20 minutes from the main areas of central Florence, like the market and Duomo. But it is also a nice walk up to the hills and more scenic mountain areas like Fiesole. He has a large back patio area with trees, and you can see the sun rising over the mountains in the morning.
There are not a lot of businesses close by, but there is a lovely shop next to the bus stop that serves wonderful cappuccino and surprising citrus zest croissants. And there is also a pharmacy right across the street if you need something.
One note is that even though there are two sofa beds inside the room we stayed in, you need to tell Alessandro ahead of time if you want to use both of them. He will assume you only want one bed even if there are two people booked for the room. The friend I traveled with had stayed with him before as a single, and just assumed we could easily use both sofa beds.
Oh, there is also an on-site washing machine (laundry soap is provided), which is a real treat in the middle of a four-week trip! And Alessandro helpfully printed our boarding passes for the next leg of our travels,
By the end of our four-night stay, the place felt like home and I was sorry to say good-bye.