Our stay at Vanna's place was amazing! There is a bus system but Vanna's son (who greeted us when we arrived) told us it wouldn't be necessary as everything was within walking distance. Which is true! Piazzale Michaelangelo is a 20 minute walk, there is a cafe right down the street with great prices (€2.50 for cappuccino and cornetto). The duomo and everything central is about 20 minutes as well.
The room was very clean and had A/C.
We were very very pleased with our stay