Stay in the apartment of a chef who will give you great advice about where to eat, drink, shop for food! We went to several of his recommendations and found them exactly as he promised. (Favorite: a wife bar across from the Pitti Palace with *knowledgeable* young servers who could but have been kinder to neophytes.)
Stay on a quiet street minutes from the David! Near the university and the archeological museum.
Rely on Michele to order a taxi for 4 am. !
If I'm ever lucky enough to come back to Florence, I hope to stay here again.
Note: low ceiling in the sleeping loft and narrow stairs from there to the toilet should be taken into consideration. Leave a light on to guide your way in the night.