For me, this room was centrally located and easily accessed with an elevator. I walked everywhere except for the bus I took frim the train station when I arrived. I got out at the Palazzo Pitti, and from there it was just two blocks straight down the street (the street name changes partway down). Go another half-block and you are at the Ponte Vecchio. Many famous sights are easily within easy walking distance, maybe 1-2 miles; and Florence is relatively flat, making it very walkable!
The room was very spacious with a private bathroom; and the air conditioning made the it perfect for a summer visit. The kitchen and a big dining/sitting room are available, so you feel that you have a whole apartment!
You don't hear the activity out on the street because the room opens toward the center of the building. A little table and chair are on the balcony with some container plants, giving the feel of a garden!
Marzia was especially attentive, even checking to see if I was OK when I didn't come out of my room for more than half a day. (I slept in, then got on the Internet to plan the next leg of my trip.)
I would definitely recommend this room and these hosts.