To address the noise issue, which some have complained about in the reviews, it may be an issue for you if you are a very light sleeper. That being said, we slept with ear plugs each night and were not bothered by it AT ALL. All things considered, the location of the apartment and the apartment itself makes it completely worth it.
Palazzo Vecchio / Uffizi gallery / Ponte Vecchio- 3 blocks
Duomo- 7 blocks
Santa Croce- 3 blocks
Train station- 15-20 min walk (we walked with our luggage no problem)
Best sandwich shop in Florence- 2 blocks (All’Antico Vinaio)
Gluten free bakery- 1 block (incredible bakery, everything in it is gluten free and so delicious)