Pros
+Very comfortable bed (most comfortable of our 2 week trip to Italy)
+Nicely decorated room
+Clean
+In a "real" neighborhood, not the tourist center
+Walking distance of the major attractions
+Daniele's suggestions of sites to see
+Very close to bus stops

Cons
-Plumbing in the bathroom makes loud noises (like a pump running) - I was concerned when coming back late at night that it would be bothersome to Daniele.
-No screens on the doors. Slept with the doors slightly open because it was cool outside and didn't want to waste energy with the AC. Didn't realize that there were mosquitos in Italy. Woke up with many mosquito bites.