If you want a central location, this is definitely the place for you! Literally a 5 minute walk to the Uffizi and lots of great shops.
I'd suggest some earplugs if you're sensitive to noise because you are so close to the town hall..the bells stop ringing between midnight and 6am.
There are 89 stairs to get to the apartment, which is a good workout, so make sure you have everything you need before you leave 😉.
David is a great host, this is our second stay in one of his apartments and we have always had a great time.