This is an amazing AirBnB with an incredible host. Marco was a pleasure to deal with from start to finish. He supplied us with personalized, robust, and useful information regarding sights (including some not found in the guidebooks), restaurants, and shopping location. When we had a SNAFU with our Uffizi tickets, Marco was incredibly helpful and helped ensure that we were able to get in. And Marco's recommendations were perfect. We liked Marco so much that we invited him to come stay with us if he is even in our neck of the woods.
Now for the location. The apartment is located in a terrific spot, right on the square facing Santa Croce (which itself is worth a visit, as it houses the remains of various Renaissance-era notables). The apartment was immaculate and extremely comfortable. It was bright and lively, and decorated tastefully with photos and other artwork. We were in Florence during an unprecedented heatwave, but the apartment's air conditioning was more than up to the challenge, ensuring that we had a cool refuge from the afternoon sun.
In short: This is a terrific location, and it would be hard to beat for a trip to Florence.