We had a fantastic time in Florence staying at Stefano’s apartment in Santo Spirito! Highly recommend Gusta Bar around the corner as well as Toto Atto II Pizza nearby and the incredible authentic Indian restaurant New Delhi a short walk away. The stairs were no problem- even for me and I was pregnant at the time. I would only worry about the climb if you have trouble walking. Beautiful views and not too loud at night on the weekends as long as you turn on some sleep noise.