This is the place for you if you want to be in the center of the action! The place is a bit quirky and the one thing to account for is the many sets of stairs you'll need to climb - but it's worth it for the great view of the Duomo bell tower.
The location is absolutely perfect if you're only in Florence for a few days and trying to fit in all the main sites. We walked everywhere - never longer than 15-20 minutes to get to our destination. Really solid little cafe on the corner (Coronas Cafe) that we grabbed espresso and pastries at before heading out each day. And check out Grom for gelato!