You can't get a better location than this. The only way to be closer to Palazzo Vecchio is to actually be at Palazzo Vecchio lol walking distance to basically anything you'd like to see in the old city. Like people said, there are quite a few stairs to climb, but nothing a healthy adult can't handle. The view is worth it though. I loved my stay in Florence and will be back. When I'm back I will gladly stay at Enrico's place again.