I stayed at Antonella's for 3 nights.. The room is pretty and clean with a view of Duomo. Antonella (and also her son, Lapo) are very nice host. They made me feel comfortable, even when I disturbed them at night due to my clumsiness -can't open the door :(
The area around is very quite, but it is nearby the bus stop that can take you to the tourist spots (take Bus #6 or #14, it can take you to Gallery del'Accademia, Duomo until Piazzale Michaelangelo)
You also can easily find Conad City (supermarket) in front of the building.