The loft is super hip and groovy and right in the middle of a bustling street. You can get to many of the sights on foot, and there are plenty of supermarkets, restaurants and cafes within a few feet of your door. The AC and wifi work great, and it is equipped with a nice shower. The hosts are easy to get in touch with.
Two notes:
1. For families traveling with younger kids, I would note that they would probably want to sleep in the downstairs room, since the loft bed stairs and bannisters are a bit more open than one would like.
2. While parking is close at a garage with a great and helpful staff, I would strongly suggest avoiding driving in Florence. Trust me, it will make things easier.