We had a lovely stay in Emanuele's apartment in Santo Spirito. I highly recommend the neighborhood in Florence rather than staying elsewhere in the city. This neighborhood was homey, active, had many lovely restaurants, easy access to grocery and pharmacy stores and was 100 feet away from what I think is the best gelato in the city.
The apartment is cozy/comfortable with all the amenities that you need for a stay of a couple of days. We live in the suburbs and found that the noise level in the bedrooms was just fine for sleeping. The living room is on a busier road (for Santo Spirito) and there was some lively town noise that we found to be quite acceptable.
Emanuele was a fantastic host, very responsive to emails and a pleasure to work with. The welcome book that he and his wife created is fantastic!