The place is very near the heart of Florence. Just a couple of bus stops away. And the bus stop to take to Florence is literally right across the street. Bus #17, for 5 or 6 stops, depending on where you want to go, will get you to the heart of Florence in about 15 minutes. Margherita and her boyfriend are also very helpful to us both during the checkin process (we needed a slightly earlier checkin due to our arrival time, and quite a bit of help with our luggage) and checkout process (we were having trouble getting a taxi and Margherita helped us reserved one).
The place also has all the amenities that we needed. Fast Wi-Fi, washing machine, fan(s) to keep the air circulating etc.
Highly recommended.