Me, my wife and our adult son enjoyed three nights here in May 2014. For me, the deciding factor on this listing was that you get to sleep less than 100 yards from where Lorenzo the Magnificent and Cosimo are sleeping, though of course in a different way :) It's nice to walk out of the unit and see the Medici Chapel right away. You feel centered in the history. The apartment is easy walking to both the train station and the core of Florence tourist attractions, and two Despar groceries, both with different inventories, are close by. There is a whole wall of closet space and more clothes hangers than I've ever seen in a guest lodging, and the promised amenities such as dishwasher, clothes washer and wifi all worked well. My son was happy in the foldout sofabed, and even with that extended there was plenty of room in the living room. You look out your windows on the real red roofs of Florence! There's a lot of life on the streets below both day and night, and you feel in the center of things. As others have noted, you walk some stairs, but the interesting thing to me is that they looked a lot like the stairs in the Uffizi, so the stairs themselves seem like part of the Florence's history. We were happy here.
In terms of the hosts, Ilaria is super helpful in advance, and there seems to be a whole family who is managing the apartment. They do it with smiles and a strong sense of helpfulness. They were very flexible on our departure and throughout the stay, which we appreciated.