This stay was excellent! 5-10 minutes walking to the Duomo, Accademia, Uffizi and 20-25 minutes walking to Piazzale Michelangelo. 15 minute walk from the train station. There are restaurants and bars just around the corner and we felt very safe. The stairs, of course, are something to consider but if you’re able to walk all around town, they should not be a problem. Luca even helped us in with our luggage upon arrival.