Great location, you walk about 30 steps then you are right at the plaza where the Duomo is! It's unbelievable! We also walked from the train station to the place which is about 15 mins walk dragging the luggages through the cobblestones. It's in walking distance to a lot of things, restaurants, touristy places, museums, supermarkets, gelato shops lol etc.
The only thing I would warn people about which Mariella already did listed out in her AirBNB is that it could get noisy. It is right in the middle of the city so you will hear some of the crowd downstairs, it's a lot better than I expected. Out of the 4 nights we were there, only the Friday night that got a little out of control with drunken group of middle-age men all talking out loud outside past midnight. I don't even know where they came from since there's no restaurant directly downstairs. Fortunately they left before 1am. The fire station is right below though, we hear fire truck multiple times a day. And another noise maker was the AC in the living room with the squeaking sound, we had to close the bedroom door and have some sound machine playing to cover the noise since we are light sleepers.
The place is pretty big for being right in the middle of the city. The only thing that I would say is small is the shower, probably the smallest shower I've ever used but we managed to make it work, it's definitely interesting.
There's a washing machine and drying rack which is very useful. There's also stove and all the pots & pans and everything you need if you want to cook. Fridge is good size as well.
Overall we were really happy to stay at this place, we were able to use it as a home base and come back in the afternoon after a lot of walking before heading out for the night again! :D