Casa Colonna is an extra walk to the Duomo area but that's what also makes it nice and quiet, away from the tourist crowd. There are plenty of restaurants, grocery stores and bakery nearby. The rooms are cozy, and we enjoyed the balcony with great views of the torres and Duomo. It's also nice to have a half bath in the main bedroom.
Rosy and Ramona were very responsive and gave us plenty of suggestions. Rosy also got us a cab right on our doorstep on our last day. They helped make our stay in Firenze memorable.