You can’t get any better than this Airbnb location. It’s 30 seconds from the Santa Maria cathedral, it’s 10 minutes from the central market, 10 minutes from the Vecchio museum and Uffizi.
The Airbnb itself is clean and tidy, it has everything you’d need, including a clothes washer and clothes drying rack. The heater is nice and warm (10°C outside at the time I stayed). The whole apartment building is quiet, easy to get in and out, feels very secured, and has two elevators!
Our host, Azadeh, responses promptly to all messages over Airbnb, has very reasonable house rules, and extremely informative on different attractions in Florence.
I would totally recommend Azadeh with her few different Airbnb units to anyone visiting Florence.