Sandra 's house is in the centre of the city. Uffizi is behind, galileo museum is about 300m away, etc. There are plenty of eateries and shops, it is about 100m from the famous sandwich store, All' Antico Vinaio. I could go anywhere by walking.
The house has 2 bedrooms and 2 bathrooms and a comfortable living area with kitchen. There are oil, salt, spices provided if you wanna cook.
The only thing you've to worry is to bring up the suitcase in a narrow stairs to level 1 but that is only twice. I will still choose to stay in Sandra's house if I am going back to Florence!