Alberto and Camilla's apartment is very central. You can walk to the Duomo easily, the Uffizi Gallery, Ponte Vechio, Boboli Gdns, Palazzo Pitti, leather market etc. We don't like driving in cities, so the aspect of walking everywhere suited us very well.
Alberto is a very responsive host. If you have questions he will get back to you very quickly, and he doesn't mind how small your question is.
One thing to be aware of is if you need a taxi you may need to book in advance. We didn't do this on check out day and couldn't get a taxi. I was anxious because I didn't want to be late checking out. So I texted Camilla who ordered us a taxi, which arrived straight away. She said to get down stairs quickly as the taxis don't wait. We clattered the cases down as fast as we could and got there in time.
Also, don't take tons of luggage (like we did) as the apartment is on the 3rd floor and the stone steps are very steep!