You can't get much more central in Florence than this! Stayed in the "Lonely Traveller" room =P It's exactly as it sounds, a fairly small room for one designed for you to not be it, because you're supposed to go out and enjoy the sights and sounds of Firenze, they had some spacious larger rooms that I saw while there if you need them =)
I got some great suggestions on places to go and they even offer wine trips out to the countryside sometimes, but I wasn't on any of those this time around so that'll have to be another time.
I had one or two issues pop up, mostly due to my own cluelessness, but they helped get those sorted straightaway. The kitchen was dangerous, in that it had a free-to-use coffee machine ;) Other than too much coffee, they had breakfast available every morning and some wonderful art on the walls and notes by previous stayers saying goodbye (which I forgot to do).