Simona's place is beautifully finished with great attention to detail. The kitchen was extremely well-equipped and included both a toaster and an American-style coffee maker, a somewhat rarity in the land of espresso. : ) The apartment is about a mile E/SE of the train station and roughly 15 - 20 mins walking to the Duomo. Included were provided 4 sets of luxury bath products and the softest towels, all of which were greatly appreciated!
Simona's apartment is on the third floor (no elevator) but steps are not too narrow or steep. Both bedrooms face the street, and although it is not too crowded, cars, buses and motorcycles go by regularly. If you are used to sleeping in a quiet environment, this will be a bit of a change. Additionally, the upstairs neighbor had a number of people over one night and paced across the floor for over an hour at 3am. It was a disruption given our jet lag on the first night, but after that we slept reasonably well.
Regarding location, we loved the restaurant immediately downstairs, Trattoria Cesarino, as well as the nearby Sant'Ambrogio market. Overall, I'm not sure you'll find a nicer place in Florence. One last quick tip, the washer's Eco setting took HOURS, so recommend putting it on Cotton instead.