This was my first trip to Italy and I felt extremely comfortable with all aspects of this loft. Check-in was easy, very safe residential neighborhood, and communication was great leading up to our arrival. It is about a 15-20 minute walk to the southern downtown area, the less touristy portion of the city. This is where the taxi parking lot is as well, however there is a taxi service you can call for a taxi pickup.
This is a beautiful loft in a beautiful area, I would return for another stay.