Value for the location was great. Air conditioning in bedroom a godsend with days in June hitting 90's. Also does a great job blocking out street noise at night. As others have noted, it's a popular street for walking tours and some late night revelers and our visit was inadvertently timed with the famed Calcio Storico at the end of the street (soccer meets rugby meets mixed martial arts) so it was never dull.
Pay attention to the stairs- 76 stone stairs and you'll want to plan accordingly! (Our mistake was one large heavy suitcase!)
We loved having the kitchen to make meals with a range of products from Conad (local grocery 5 mins away) to Sant 'Ambrogio market (7 mins?) which was far closer and less touristy than Mercato Centrale (although it's a good spot for A/C, wifi and a cool drink while you plan your food shopping from the vendors below.)
Mosquitoes not too bad but we closed up frequently.
As others noted, might suggest new mattresses but the one on the futon was super.
Very clean and crisp and nice shower to enjoy at the end of sweaty exploring.
Guido let us know about "Ditta Artisanale" coffee place at corner of Via Rustica and de Neri. Two mins away.
Our favorite gelato place was on Via dei Benci with crisp green/white sign across from Red Garter Steakhouse.