Casa guido is a great option for the ones who want to enjoy Florence on foot. All city highlights are located within 10-20 min walking distance. There are plenty of trattorias and even grocery shops nearby.
The place itself is cozy and fully furnished, and Lorella even provided us with some starters.
As our train arrived early morning, we could check in about 8, and got enough time to recover. Also, Lorella was always responsive and absolved our demands fastly.
Notice that the appartment is located in the 4th floor, so it may serve you as training to climb Brunelleschi's dome :)
All and all great place to crash!