The apartment is very central (in front of Galleria dell'Accademia) and with walking distance from the main sights. However, for being an old building, expect a LOT of noise from early morning until late night in the two bedrooms facing the street.
The only problem we had was related to the check-in: the person responsible to check us in (Lidio) spoke very little English (only Italian and Spanish). He agreed on an early check-in (after 12:30), but was late to arrive. Once there, he realized he had forgotten the keys. Another man then came to bring the keys and we finally had access to the apartment at 13:47, only to notice that the place hadn't been cleaned after the previous guests left. The two men told us to come back after 30 minutes so that they would have "enough time" to clean the apartment.