This "skyline" flat in the attic of a 18th century building is really an amazing space. My wife and I thoroughly enjoyed the location, the views, and the authentic shops in the neighborhood. A glance out the window identifies four very close reference points--the Duomo and its bell tower (3 min walk) and the Bargello/Museo Nazionale and the church steeple near it (2 min walk).
One tip to any of you Americans, close the windows at night to avoid the notorious Florentine mosquitoes.
Final tip, be prepared to climb 92 stairs to the flat. It is well worth the climb!