Fantastic space! Will definitely stay here again when I am back in Florence.
In terms of location, you cannot find anything more central and convenient. It is around the corner from the Domo and any other site or museum. There's a cute cafe next door for breakfast, a grocery store at the end of the street. It's literally in the middle of Florence!
The apartment itself is beautiful! Tall ceilings that are extraordinarily painted which really add to the Italian feel. It is very clean and comfortable - the building is also very safe and beautiful.
For recommendations nearby the flat I had the best pasta of my life at Il Vezzo (make sure you make reservations - this goes for most places in Florence though!). Best Aperol Spritz at La Mangere (do not go for breakfast though - it is very crowded!) and best cocktail bar is Vanilla (so good!) and likewise at Rasputin (a speak easy). You can get an amazing view from the Continental rooftop and a drink at the St. Regis is likewise recommended!
For museums make sure you book tickects ahead (I suggest the Uffizi in the morning and the Academi). The Biboli Gardens and Piazza Pitti were my favorite though! Likewise, book ahead online.