The location is perfect--literally across the street of the Accademia (this means that you roll out of bed and 10 min later, you're looking at the statue of David). Lots of great cafes and shops in the immediate vicinity. Daniela's recommendations (posted conveniently on a board in the entry way) were golden--esp the Skipper!
There were some minor downsides (it's an older building, so sometimes there was an odor from the bathroom sewer pipes--not the host's fault, but still unpleasant). The ornate headboard we loved, it turns out, was not actually attached to the bed (which we learned the hard way). None of this was a huge deal--we spent most of our time out and about.
All and all, a good space and a fantastic host.