Could not be more central. An amazing view from the roof terrace looking onto the Duomo. The apartment is on the top floor and is quiet, we couldn't hear anything from the streets below. The apartment is big and clean and lovely. Reading other reviews I was expecting the stairs up to the apartment to be a killer but they totally weren't, and we climbed them with suitcases no problem. 2 minute walk to Duomo, about 4 to the river. Everything is really close.