We left the Loft this morning - and we already miss it a lot!! We had a wonderful time there and fell in Love with Palermo.
Perfect Location in the Old Town, perfect view, perfect communication with the Hosts, Supermarket around the corner, Central Station nearby ... really nothing to complain about.
You should be good at climbing stairs (we are)! And better bring earplugs: nights at Piazza Sant'Anna can be surprisingly noisy (we did, and needed them).