We have spent the last week of April 2022 in Manuela's apartment and I can say that the previous reviews and photos are very accurate.
Manuela was very communicative throughout our booking process and then during our stay. She helped us with advice on how to navigate the surrounding areas, where to go and eat and what were the best options for visiting the important landmarks of Catania and the area.
The location of the apartment, as others have said, is about 25-30 mins walk to central train station and maybe 15-20 mins to the city center, so bear that in mind. We found busses to be very unreliable, and they depend on the city traffic, so your suggested option is to walk from the apartment to the central train station and from there go to any destination of your choosing. We visited many cities on the east coast (1-2-3h distance by train).
The apartment is very clean. I mean religiously clean. And we loved that. It is by far the most important element of our choosing an AirBnb location. You have everything you need in the kitchen if you want to cook (we never cook on trips, but good to know) and also the bathroom has a walk-in shower and spacious area for sink, with large mirror. As others have mentioned, the noise from outside is indeed very loud; but if you only come back after a full day of visiting places, and you will be tired and get to sleep, I don't think you'll care much. However, it is an element you should consider if you are sensitive about noises from the street.
My other 2 decision elements (apart from cleanliness) are shower pressure and comfortable mattress, which this apartment met with high colors, so we were very happy about this.
If we return to Catania, we hope to stay here again.