We had a great stay at Andrea's place in Ortigia. The location was a block or two from everything! The water, the market, great restaurants, and even ancient ruins.
Andrea is a very helpful host who was quick to respond to all of my questions. My only drawback would be having to take a very quick 5 minute shower or you would have a cold shower. Max 2 people. There's no way you could fill the big tub even half way with hot water. I imagine a cold shower would feel great in the summer however!
We were pleasantly surprised to see a well stocked kitchen and happy with the quiet streets, and comfy beds.