Highly suggested apartment in the centre. It is located at the top floor of a building in the heart of the city centre, precisely in Vucciria. That makes it quite noisy during the night, but I did not find it disturbing at all. Just go in the streets and enjoy the night vibes. The best bit is the two level terrace on the top: great view on the city!
Being in the center means you cannot get there with your car, so you need to leave it at foro italico and walk 5 min from there.