Manuela's flat is ideally located in the historical neighbourhood of Palermo. Fully equipped with all you need to cook if you stay for a few days, it also has a beautiful rooftop where you can have a meal or just read in the sun. The bedding is comfortable and the flat is very clean. You'll find a lot of bars, restaurants and markets in the area (particularly recommend Funnaco PizzaLab for amazing pizza, Osteria Nonna for fresh and copious seafood meals, and Ai Bagnoli for a tremendous aperitivo with original cocktails) and will be within walking distance from most sights, the historical quarter, the harbour, or the more recent part of the town.
If you fly to Palermo, the easiest is to take the train from the airport to Palermo Centrale (6 euros per person) and walk about 10/15 minutes to the flat.
Fully recommend it to a group of 2-3 people for a lovely stay in Sicily!