Highly recommend Zikihouse..
Emanuella and Andrea are kind and welcoming hosts. Place is very clean.. spotless. Simple and modern in old but very well kept building. Quiet, safe neighborhood.
Tram is just around the corner and it takes you in 10min. to Central Station from where you are connected with subway to the rest of the city.
If you prefer walking, city center is 20-25min. walk with obligatory stop at Piazza Risorgimento for gelato..
Enjoy Milano.