Organize an interesting trip (yes), call a friendly company (yes), find a spacious apartment in the city center (YES!).
We stayed with 8 people, and I can say there is enough space for a big company. Milano is a tourist city, so anyway, you will be out for most of your day.
3 rooms with twin beds, 1 with two single, modern living room with tv, PS2 :) and sound speaker, kitchen with everything you need, 2 just great bathrooms (I fell in love with the far one), and a hall connecting everything together.
Right across the road, there is a small supermarket, where you can buy everyday supplies.
The nightlife of Milano, Navigli is in 5 minutes by walk. Stay for drinks, food is better to find on neighbors' streets. Duomo and other architectural places are about 20 minutes walk.
Summarizing, roomy apartments within walking accessibility of touristic places, ah yes, and a great value!