Fabrizio’s place is really central in Milan with a lot of historical monument within reach by foot (including il duomo). It is in the heart of the Brera neighbourhood which is one of the best in Milan.
The neighbourhood is lively with lots of bar and restaurant (the street is crowded at night) but we hear nothing at all in the apartment from outside noise.
The only “issue” is that currently there are some works done in the building but honestly nothing that disturbed us.
I would definitely recommend as the apartment is really comfy, spacious and clean.