Donatos apartment was a perfect stay for our 4 day trip to Milan. It is located in a lively street in the Navigli district with a lot of nice shops, bars and restaurants. You will discover new things everytime you leave the house :-) The city center (Piazza del Duomo) is a 30 minutes walk away, or you can use the tram / metro (10 mins walk).
I wouldn't suggest to drive by car in Milan. We parked our car in the Linate Airport car park and used the bus to get to the apartment (1 hr). You can also use one of the many ATM car parks, but we read some bad things about security and chose this slightly more expensive option.
We would definitely stay here again!