Rafaela is a very nice host, very quick response. We love her place, surrounded with good restaurants, bars, etc.
Its only 5 minutes walk to subway, Duomo is only 2 stops from this subway.
Milano central is around 15-20 minutes walk (we walked with 2 big luggages), if you feel not to walk, you can use subway or taxi (€10).
The apartment itself is quite small, but it doesn’t really matter for us.
We certainly will stay at this place again whenever we visit Milan.