This place is great for a weekend in Milan! The nearest metro stop is a 10 minute walk, and then just a few minutes on the metro to get to the center. It's also a 10 minute walk in the other direction to the Garibaldi station so that's convenient as well. The neighborhood, Isola, is great for a launching point. It's lively at night but not too loud; there's plenty of restaurants that are really nice but also some local spots with great pistachio croissants!! The people were super kind in the area as well. I'd recommend going to Miscusi during your trip, it's a chain in Milan but it's soooo delicious and basically across the street from Andrea's airbnb.
The large bed on the loft portion was super comfy and despite being a loft, it was actually super fun to sleep up there. The apartment feels spacious enough for 3 people easily. Bathroom is clean as well. We didn't really use the kitchen but it seemed good as well based on size and accessibility. The apartment is on the 4th floor but there's an elevator so that's nice. Check-in was simple and Andrea was kind and responsive to our messages. Definitely suggest staying here!