Tiziano's loft is THE best place to stay in Milano if you're searching for a central location. It's really just no more than a few meters away from the duomo. The subway stations are also real close and It's really easy to get around in Milano that way.
The loft itself is very confortable, everything was clean, and is well furnished, plus the entrance is quite classy.

Pros :
- Very central location
- Very quiet, even next to the trams and busy central-city life
- Completely furnished, laundry and towels provided
- etc..

Cons :
- ..... none that I can think of...