Francesco's place is close to the Navigli area. It's a very active area at night, so if you are looking for fun things to do close by this place is recommended. Beware that it can get a bit loud at night. The room I stayed in had 2 separate beds, so if you are traveling with a partner, keep this in mind.
Francesco and his wife are excellent hosts, they were very nice to talk to and offered be a delicious breakfast every day.