I've been staying with Piero and his family for one week. I was very surprised when I've moved in by the huge separated area I was going to stay in. This is not just the room, but the whole penthouse with king size bed, huge windows and your own private bathroom, terrace with a place to chill, big table, sofa and wardrobe. Also Piero's house is very beautiful and well designed. I really appreciate the privacy during air bnb stays and with this family you feel perfect balance in privacy respect and friendliness. The house is very clean, there is a nice garden, I didn't use kitchen much but it's super equipped.
About the area I think every tourist will appreciate that the house is located in Navigli area, cause this is one of the most interesting and fool of life areas in Milan. Lots of restaurants and bars are here. 1 minute walk to the Lidl supermarket. Tram #2 will take you directly to the city center and Duomo in 15 minutes. But the house is located inside the street, it is a small super pretty private street with the same houses, so there is absolutely quite and safe. Also you can find the best ice cream in Milan in the Gelateria della Musica.
As for me, it is one of the best options to stay in Milano, both for couples and individuals. Highly recommended