This Bed & Breakfast is the perfect place to stay for those who like to walk. While it is close to the metro & buses, within less than 5 minutes you are standing right in front of the Colosseum. We didn't feel the need to take the metro because we wanted to be able to take advantage of seeing everything.
Over the course of our 3 night stay we saw everything that we wanted to. We also did a day excision via bus to Napoli & Pompeii. (The company even picked us up from there).
I highly recommend staying here and would definitely come back.