There is no place in Rome like Borgo Pio - one of the most beautiful and non-tourist (at least in Winter) streets in Rome. And Federico's apartment is as atmospheric as the street. If you do not want to feel like toursit, stay here. The apartment has everything you need with some extras (like the second bathroom). And Amanda and Federico are super hosts welcoming you with bottle of wine and delicous Italian coffee. Ypu will get to Vatican in 3 minutes and cross Tevera via Pont d'Angelo in 5 (so it means that you will see one of Europe's best views in 4 minutes - lokk from the brodge towards St. Peter's basilica, especially on sunset). No better place I know. The only small disadvantage is the noice from the street at night and in the morning. But just bring you earplugs and you will be fine