Being here is just like being at home. Incredible cafes and restaurants around. Supermarket is very close by. They have a special table per room and breakfast, they have an espresso machine, which is a fenomenal add if you love coffee.
You can walk or get to the Vatican by Metro (just one Metro stop Cipro-Ottaviano/San Pietro direction to Anagnina). Walking to the Vatican is 15-20 min. Pretty safe area. Eugenia is an incredible host.