Domus Avi was a good stay. Everything was clean and as pictured. Our room was the smallest of the rooms pictured (and smaller than they appear in the photos), but since we spent most of our time out and about this wasn't a major issue. The bathroom was quite small though, the second smallest of our Italy tour, not so comfortable.
We had requested a 7 am taxi from the front desk upon check-in and did not receive confirmation of this, so we ended up just Ubering to the airport. They apologized for not confirming (and said they had in fact reserved a taxi for us) but this did make for a bit of a stressful wake up (once we realized we never got a response and needed such an early ride). Thankfully Uber works in Rome and we woke up early enough to schedule the pick up through the app. We understand it was an honest mistake but it was quite critical to our experience.
Location wise this is a short walk from the Colosseum but we did prefer staying closer to Piazza Navona & the Vatican for dining and exploring, so we did end up on that side of the city and had a longer 25-minute walk back at the end of the night (which is a lot if you've been walking all day). Just our personal preference, but something to keep in mind (also the main reason we would not stay here again).