Letizia and Gianfranco are the perfect hosts - they are extremly helpful and responsive. They explained in advance how to get to their place from the airport by public transport. Although Letizia speaks only Italian and French (Gianfranco is the one who speaks English) and I don't, she is so expresive that we manage to comunnicate. On the first day Letizia showed us where to eat and drove us by car to an absolutely magic place - when you look through the keyhole you have a wonderful view at St. Peter's Basilica.
The appartment is cosy and has an "artistic soul". It is perfect for two people and has everything you need. We were pleasently surprised to find some food in the fridge, coffee, tea and fruits.
As to the public transport - we do not mind walking, so the location was ok for us. There is a bus stop very close to the place, however the only bus that stops there (no 16 to Termini) drives relatively rarely. In 500 meter distance you have another bus stop where you can take a bus no 51 to Piazza Venezia. When you walk 1200 meters distance you can reach Metro A station Re di Roma via Termini, to Vatican.