A great location right in city center which allows easy access to all the attractions, restaurants and shopping. Our party of 6 were comfortable in the apartment relaxing and sleeping. Weekend days can be more noisy in the late evenings, so would recommend having the shutters closed (per Nicola), which was helpful.
We walked almost everywhere, however if you need a taxi, you will need to walk 3-4 blocks to a main street to locate. Nicola did set up transport for us to the airport, so you could always work with Nicola to get a contact to set up public transport when needed as well.
All in all a very nice three day stay for us.