Trastevere is a beautiful place to stay that is far enough out of the city to experience the authenticity of Italy but close enough that a 5 minute walk to the bus or tram gets you to all the sites. The neighborhood is full of life, lots of delicious restaurants and shops.
The only reason I’m leaving a 4-star review is because we weren’t anticipating the street noise. Though the apartment is on one of those small lovey Italian streets, the pedestrian and scooter traffic went well into the night.