You won't find a more central location--seriously. You can walk *anywhere* or catch a cab or bus one block away. The block below the unit is full of restaurants and shops and evening strollers, but the unit is settled at the back of the courtyard and the only noise we heard was lovely music from a neighbor's window. If you have trouble with mobility, this might not be the best, as it does feel like a long ladder from one room up to the next up to the next, but if you are up to the stairs, it is a delightful trip back in time with the beautiful, old, dark wood beams and staircase. We LOVED it. Even the spacious bathroom, though you might plan on only bathing (not showering), as the shower is only about 5 ft or 1.6 m high! Beds were very comfortable, linens were crisp and clean and new, and the kitchen was well-equipped (we even made a special Easter dinner in the space).
What you can't quantify or adequately describe is HOW INCREDIBLY HELPFUL Luca was. We have stayed in a dozen AirBNBs with great experiences in each one, but Luca went far above and beyond for us, more than I would even want to ask of a host. The airline lost our luggage, and he essentially tracked down the delivery truck and made them commit to a delivery time for us which meant texting with us and calling several places on our behalf late into the evening. I'm not suggesting that all of you take advantage of him like that! ;) But I did want to share how kindly and hospitably he treated us beyond what is expected.
If you're traveling with kids (over 6), this is awesome--they'll love the loft!, and if you're a group of adults, you'll appreciate the separate spaces available to have some privacy yet feel like you're on the adventure together. We were 3 generations, and we each claimed a level!