Eleonora's apartment is cosy and has all the needed amenities so we felt really confortable while staying there. Also the neighborhood is really nice with supermarket and other stores/places to eat only a few blocks away.
It takes around 10 minutes to walk to Trastevere's main area. Also the Vatican is within a walking distance. For other parts of the city you might take tram or bus, taking into account that depending on which option you pick there are going to be a few stairs in your way.