The location is absolutely great. A couple of blocks from the Vatican Museums (2 minutes walking), ten minutes to St. Peter's and five minutes to the metro (which in turn gets you to Termini in 10 minutes or the Colosseum/Forum in 20 minutes. Alessandor was great as a host, we have three children and he also helped with a Pack&Play for our little one.
The kids loved the lively neighborhood and the water fountain plus the elevator in the building.
Yes, there is street noise, yes, that's to be expected in a city like Rome if you want to be in a central location.
The neighborhood is great for kids, supermarket and restaurants within 5 minutes of walking.
The place is very, very clean and safe for kids, people in the building very helpful and friendly.