we cannot recommend Federico's highly enough, by far the best Airbnb accommodation we have stayed in.
location wise you couldn't get better just a 5 minute stroll from the Colosseum with plenty of restaurants nearby, also a carrefour express at the end of the road which is open 24 hours.
we were met on arrival by our hosts who were extremely informative and were gifted a beautiful calender and a bottle of wine on arrival. Any and all queries were answered in minutes, so no stress just a relaxing chilled break.
p.s. the bed is huge