The location is the best. The Colosseum was a 15 minute walk, the Pantheon was less than 10 minute walk. Lots of places to eat right in the area and grocery stores if you want to take advantage of the kitchen. There’s a mini mart right next door which is very convenient for anything you may need quickly. There’s amazing architecture and history on every street, you won’t have to search for things to see or do.
The apartment was spacious for two people, we ended up spending a lot of time relaxing in the apartment because it was so nice. Highly recommend picking up a local wine, cheese, olives and deli meats from a store and snacking at “home” while thumbing the pages of the many books about Rome provided by the host.
The area felt really safe, even for walking around late at night/early morning (there is no one around so you can get really great pictures of monuments/landmarks).