Pretty excellent location. Abour two mins from Lepanto station and actually walkable distance to the Vatican. Neighbourhood itself seemed pretty safe with a few nice places to eat nearby. The only problem I had was with check in where I was waiting for a while to decipher how to do the check in. But the host luckily responded so manages to sort it out, just had to wait 30 mins so that kinda messed up my plans. But otherwise it was excellent :)