Overall, this is a great place for the price!
First off, we were greeted by Isabella, Patrizia's sister-in-law, and she couldn't have been more welcoming. She showed us where to go for the tram and gave suggestions for local pubs and groceries, and she offered to take us to the train station when we left. Five stars for Isabella!
As for the place, adequate space for four people, hot showers, very clean and tidy. We appreciated the tram stop right around the corner. We took the tram to Trastavere and the Colosseum directly, and to get to the Vatican, we took the tram to the Metro and made the switch. No problem as long as you know which direction you're going!
The area looks rough around the edges. Lots of noise (kept us awake at times), pot holes, and graffiti. I would not want to walk alone at night, but I felt safe with friends. This is the university area, so there are a lot of young people out, which actually made us feel better at night. Definitely a good find if you're on a budget!