The only inconvenience is... that you won't want to leave the house. It's clean and beautiful. It's perfect for couples, better than any hotel for families.
It's at 5 min walk from metro linea A and that's the line Vatican and Piaza del Popolo and Piaza Spagna are and the metro runs until 11pm, even more in weekends.
Maria is an artist and you will thank her for that because the house is decorated splendidly. Excellent communication and the price better than any hotel.
We couldn't have made a better choice.