The apartment is fantastic! The area is very nice and we felt safe at all times. There is a bus stop directly in front of the apartment so transport should not be a problem. The Vatican is accesible by foot in less than 10 minutes, in around 30-45 minutes you should be able to reach the coliseum. Communication was very smooth with Flaviana, she got in touch with me 30 minutes after I made the booking and was very accommodating. When I go back to Rome I will make sure to look for Flavianas apartment.