We loved the apartment and it was a lot larger than expected. We felt right at home here. The photos don't do it justice! It's perfect for couples and families because of the "split level" living space, with having one bedroom on each side of the house. The one thing we had to get accustomed to ... and it's only because we live in a very quiet neighborhood in the US ... was the bottle collection from the restaurants and bars on the streets as well as remembering we were in the city and the noise from party-revelers can be a distraction.
The central location is fabulous in the Old City. We were able to walk everywhere. For US who don't want to turn on your phones, here is a tip for navigating your way around since the streets in and out wind about. While in the wifi range of the apartment, map your destination through your GPS and hit start. Then turn off wifi ... the directions will still come and talk you through getting from the apartment to your destination. Works like a charm.
My other suggestion is based upon your arrival. Set a SPECIFIC time to meet the hosts. They don't live on sight and must meet you in order to let you into the apartment. The suggested driver was great and the transfer time from FCO to the apartment is about 45 minutes. He will stop and make a phone call to tell the hosts how close he is to dropping you off but you need to know what time that is. Otherwise you are dropped off in front of the door with no idea what comes next. The neighborhood is safe ... that is not the issue. It's simply not knowing what comes next so be specific in your plans. The driver may open the door to the building but there is not much space for waiting.
One absolutely DELIGHTFUL HIGHLIGHT was the local coffee shop around the corner (almost a fish hook "around the corner") to the right as you exit the building. It's called Forno Monteforte and the coffee and pastries are brilliant! Great place to people watch too! The staff are welcoming and so efficient. We went daily for our morning start and within a few days, they recognized our faces and preferences to the point where we didn't have to order, just pay! Also there is a small supermarket around the corner too ... come out of the apartment, take a left and then your first right. It's up past the corner restaurant. Small deli, small selection of wine and beer but enough to get you started with some essentials for your stay.
Beyond that the Pantheon is a 10 minute walk. The Vatican is a 20 minute brisk walk. Trastaverre is 15-20 minutes. Just to give you a better idea of the central location.