We had a great stay in Rome at Maria-Rita's apartment. She was very welcoming when she met us even though we arrived late in the evening. She told us all about the public transport and some restaurant recommendations. The bus to the centre is just across the road and the metro station a 10/15 min walk. The Vatican is walkable approx 20 mins.
The apartment is clean and spacious and the air conditioning was great as it was very hot. There is a supermarket next door to the apartment block which is extremely well stocked.
The only slight down side was that the shower cubicles were very small and the water temperature could be a little temperamental!!!
Apart from that would thoroughly recommend.