This was my first time in Rome and I would strongly recommend this unit to other first-time or repeat Rome travelers.
This is a large unit with more than enough space for 6 people. The location is very central (to the tourist area) and very safe. There is shopping and good food all around - if you are not sure where to go, use the Internet to find the best places. You can definitely walk to all of the major tourist sites - and I would recommend walking as the area is packed with things to do/see while on foot.
The unit itself was in a historic building (really cool!!) but also very clean and organized, with powerful AC in every room. The unit is located on a small street that is very quiet even though it is very close to restaurants and bars that are open late. I had no trouble with noise at all, and I would definitely come back again to stay here.