Very good location just north of the river and close to the Vatican. The breakfast is outstanding and with a generous bedroom and bathroom this venue is hard to beat.
Take bus 40 or 64 or Metro to stop Ottaviano from Termini.
NOTE- avoid the eateries close to the Vatican, they are overpriced, clip joints. We patronised ‘Mamas’ a little further down Via di Porta Castello and it was excellent.