Luigi and Paula's place is in a great location a short walk from metro stations. The neighborhood is great with not very many tourists so you can get access to several good restaurants that serve mostly locals. Would definitely stay with Luigi and Paola again.
The room we had was very large, perfect for dropping off your luggage and exploring the city. You get a nice private bathroom, across the hallway from your room (we found this to be common in Rome). There is a bit of street noise in the early evening but it seemed to taper off and didn't affect our sleep, but we are heavy sleepers.