The accomodation is perfect for a trip to rome. It is very well located. I only used the bus to go to Termini for trips outside of rome.
I figured the best way is to get there by sitbus shuttle from Fiumicino. It is very cheap and you can make the rest of the way (from vatican city - approx 18 min) to the appartment by foot right past castel st. angelo. So its a really nice area for a walk.
Alessio and his partner Martina were very welcoming and helpful. They give you tips about the area and you can ask them anything. I couldn't imagine a better place to stay.
The room is quiet, clean and cosy. I really enjoyed staying there. Absolute recommendation!