Great location near the Vatican and away from all the hordes of tourist crowds. Maybe a 10 minute walk to St. Peters Square/Basilica. Easy to catch a bus (just a few minutes away) to get to every where you need to go.
There was a 24 hour supermarket about a 5 minute walk down the street, which was convenient. Washing machine and wifi worked well. We used the kitchen a few nights to cook dinner at home, which was great.
Overall I'd feel comfortable recommending this unit to friends headed to Rome.