Staying at Frank's Guesthouse was certainly one of the best decisions we made during out trip to Rome! Frank warmly welcomed us upon arrival (and was very gracious about a communication mix-up), gave us a tour of the lovely space, and then proceeded to share all the secrets to a great stay in Rome. His explanations and tips for seeing all of Rome's sights, not to mention his restaurant suggestions were invaluable! The neighbourhood gelateria he recommended was especially great- we ate there every night.
The guesthouse is very close to the metro, but for the most part we were able to walk everywhere. The park across the street was also a nice surprise as a fun place to eat a breakfast pastry and people-watch.
If we are lucky enough to visit Rome again, we will absolutely stay here again.