We (two families) spend some marvelous days in Marco's apartment in Rome. The appartment offers plenty of space for 6 persons. The location is a bit outside of the city centre but thanks to metro or bus you reach all major tourist spots within 30 minutes. Vatican city is in walking distance. There are also small supermarkets and restaurants nearby, shopping centre with giant supermarket at Valle Aurelia station. The appartment is nicely furnished and we felt very welcome.
Transportation from Fumicino airport to the appartment is a bit time consuming because regular train or shuttle goes to Termini station in the centre and from there back (!) via metro to the apartment (all together about 1,5h). A small hint is that there is a direct shuttle bus from Cornelia station to the airport. The price is unbeatable cheap with EUR 6,-- and this trip took us not more than 25 minutes. Definitly an option that should be mentioned.
Whenever in Rome again I would always try to come back to Marco's apartment :)