We stayed at Luigi's appt for 3 nights at the beginning of our holiday in Italy. The room was lovely, clean, comfortable - and COOL (Rome was mid-heatwave, and I am pregnant, so the aircon was much appreciated!) We also loved having the free WiFi to keep in touch with the Olympics back home!
Luigi was very welcoming when we arrived - we met him at his restaurant nearby, and had drinks before heading to the appt. He took time to show us what we needed, and also to point out areas/restaurants that he recommends. We did not see him for the rest of our stay - but had several ways of contacting him if we needed.
It is very convenient for the Vatican - only about 5 mins walk, and for Ottaviano metro (5-10mins). It takes 15-20 mins (walking) to get to areas such as the pantheon, and getting on for an hour to walk to/from the Colloseum (but you can take the metro).
We ate at Luigi's restaurant once, and it was very very tasty and great value for money.
I would recommend both the appt and a meal or two in his restaurant!