Everything I could want in an AirBnb... clean, soft bed, private deck and gracious, helpful host. I can't imagine much of a better location at least for my first-time Rome visit. 20 minute walk to the Vatican one direction. 20 minute walk to the Colisseum and Forum the other direction. The Panthenon is just a couple of blocks away as is the Trevi fountain. Short cab ride or 30ish minute walk from the train station. And the neighborhood is full of great restaurants and gelato places.
Only possible downside... it's a four or five floor walk-up. Wasn't a big deal to me but if you're not especially mobile, might not be the best spot.