I highly recommend staying with Maddalena. Not only is the room and en-suite beautiful, modern and clean, Maddalena herself is friendly and welcoming. The evening I came in, she showed me everything in the room, and checked that it was all to my liking. She offered me something to drink right away, and even taught me how to make Italian coffee! (It was lovely.) The location is amazing - her home is within walking distance of the Vatican Museums, and if you want to visit the Colosseum and other historic sites her home is also only a block and a half (if that) from the Cipro Metro stop which will quickly put you in the center of Rome. Cipro has a lift, which is great if you have luggage, and if you're coming from Roma Termini (most airport shuttles come and go from here) you can go directly from Termini to Cipro. There's also a 24-hour grocery store within about five minutes of walking. I don't speak any Italian, but Maddalena is fluent, and she made me feel incredibly welcome during my stay. If I ever have the chance to visit Rome again, I'd be glad to stay with her.