I had a business conference in a big hotel nearby that was charging a fortune per night... but I am very happy I booked Vanella Rome Domus B&B instead! It was conveniently located, also to visit Rome after business hours since it's close to Termini and metro station. The room itself was super convenient, well equipped, very clean and made my stay pleasant and easy. I stayed for one full week and it was perfect. Did not hear noise from other rooms, although I know there were some people in. The little garden in the building makes it a very calm and nice place. Dorina and Ion are also very considerate and attentive hosts, available and ready to help. I was greated the night of my arrival (at 22.00) by a very nice person who gave me the keys and explained to me everything, and Ion met with us when we left, and transported our luggage already. As I said, they really make your stay hassle-free!
PS: I did not have the chance to test the breakfast (which is not served in teh premisces but in a 5-min walk located place) as I could not get myself out of bed in time before my meetings.