Recommended!
We used the three-person room and it is bigger and nicer than the photos suggest. The beds were very comfortable. I did not mind, but the shower power was quite low.
The breakfast was okay, don't expect a whole breakfast buffet. We got a nice sweet croissant and 4 crackers, while Emanuela's sister prepared fresh coffee/cappuccino/espresso for us.
The guesthouse is very close to the airport buses, metro and train station. If you're on a tight budget, the colloseum is quite within walking distance.
We arrived at different times, but check-in went smoothly.
In short, I'd definitely stay here again if I'll return to Rome.