We very much enjoyed our stay in Trastevere. The apartment was very modern and comfortable. Check in was easy and they were all so very helpful, they even arranged a car for us to the airport at the end of our stay. The tram line a couple blocks down the street will take you near the Colosseum and/or into town and to all the main sights you are most likely hoping to see. We were a tad bit further away from the Vatican but we chose a short cab ride there.
There is a nice restaurant two doors down but the apartment is still very quiet and in a great neighborhood away from the hustle and bustle. There are also many other places to go just down the street. We took a 10 minute walk to restaurant Roma Sparita and enjoyed it very much as well. The only drawback we felt was having to take out our garbage at the end of our stay. Other than that we really liked it here.