The whole trip was hassle free. Maria helped to organise a taxi from the airport to the apartment and was there to meet us. She quickly and efficiently showed us around the lovely apartment and pointed out a few places to get dinner in the local area.
The apartment is close to the Metro and Tram and the Vatican is about a 10-15 minute walk away.
There is a bit of noise from the tram when it passes but didn't seem to keep us from sleeping.
Loved the area and whilst it's a bit of a walk to places like the Spanish Steps and Pantheon it's not prohibitive.
For awesome coffee, go to Sciascia caffe on Via Fabio Massimo. For great pastries go to Dolce Maniera. Both are only a couple of minutes walk from the apartment.
There were 3 of us staying and we all had a bathroom each.