Luisa is a fantastic host! She gave us excellent tips on restaurants in the neighborhood (osteria scaloni was our favorite!) and was very helpful. Location wise, we were right around the corner from a bus stop which is convenient since we took it a few times (remember to validate your bus ticket). We preferred taking the Metro which is a 10 min walk and right near the Vatican. Definitely book if you want to be near the Vatican. Loved how spacious and comfortable her place was.