We have a wonderful stay at the Vatichouse. Location is close to Cipro metro and a bus stops out front. (Easy access to city transportation.) Room was good size for two people, a nice studio size. Room and Bathroom were clean. Location felt safe and quiet. I was able to walk to a grocery store near by for food. It's about a 10-15 min walk to the Vatican and a 5 min walk to the Vatican Museum entrance. You can get to the Colosseum in 20min via Cipro stop.
Barbara was a spectacular host. We had several questions and she answered them promptly.