Manuela is an AMAZING host. And her husband is very helpful as well! Manuela was delayed getting to the apartment to let us in, and her husband arrived 5 minutes later. He apologized for his English, but he was very clear and helpful. Manuela arranged for drivers to take us to the airport (two separate cars, my mother and I left on different days), and they were prompt and courteous. She even arranged to reserve a table at a nice restaurant nearby for us when we arrived, as we were uncertain where to go. It can be hard for a foreigner to know which are good and which are not great.
The apartment is a lovely home. It has everything we needed. Just a few blocks from Vatican City and the entrance to the Vatican museum, walking distance to many attractions. The neighborhood can be lively, but quiet enough that we had no trouble sleeping. Being so near Vatican City, it is surrounded by many restaurants, cafes, souvenir shops, and most importantly, gelaterie - I could have eaten gelato for every meal!
When I return to Rome again in the future (I hope I will!) I would be glad to stay here again.