The apartment itself is in a good location for Vatican and then making connections from there but you can also get bus and underground not far away.
Although it is a lovely building and very nice layout inside, We were a bit disappointed with the apartment, but that might be high standards set by describing as "luxury".
Also, I am a tea addict and there was no kettle, so when there was no sparker or lighter for the gas hob, this was also a problem. Probably someone removed the lighter previously and I had to buy another one late in the evening from a local shop.
It was those sorts of things that annoyed though. The bath and shower we found complex to use without instruction because there were many controls.
All in all, it is a nice apartment in a good location but just needs a bit of a deep clean of shower areas, more time of check in and a kettle and few bits and pieces and it will be all good!!