Pros - Roberto and his wife were extremely helpful providing us with local tips around the city. Roberto even went out of his way to book a taxi for us to get to the airport. The apartment was clean and had everything we needed. The neighborhood was quiet and peaceful. Lots of good restaurants near by.
Cons - not really any downsides. It was pretty far away (not walking distance) from all the other tourist attractions besides the Vatican; however, you can either get to it by local bus or the underground metro. The metro we found was not confusing at all. It was about 1.50€ per person.
I would recommend this place to anyone and would stay again.