Very central, which comes of course with some sounds at night. We loved the fact that we could walk to the Phanteon and also Spanish Steps. The buus for Vatican, Colosseum, AS Roma stadium, and railway station, is right in front of the house, so is a Pizza place, and a grocery store 5 min away. For AS Roma fans, there is a fan store 5 min from the house. Bus tickets you can buy at a kiosk close by. If you get out of the building go to the right there is a small restaurant where you can eat and get coffee and pastry in the morning. The only draw back is the train in front of the house, I couldn't sleep while it was running, I would hear and feel the rumbling of the train. Walking overtired with kids in Rome was a challenge, gut you can't have both super central and quiet at night. The bedroom on the first level is towards a court yard there must be a bar or so that kept us awake one night. The site opposite the apartment is now a kitty sanctuary, something for cat lovers, my wife enjoyed it. you can go an pet the cats.
One last thing, if you leave the house when checking out, you have to keep the two doors down stairs open, you can't open the first door without key, at least I couldn't figure out. We had to have a neighbor let us out. Something to remember if you leave the keys in the apartment. We got stuck in the hallway for 20 min figuring out how to leave the building. Neighbor opened the door for us.