This place is an excellent springboard for exploring Rome. First of all, Raffy not only allowed us to check in a bit early so we could drop off our luggage from the airport, but was also incredibly friendly and gave us some great suggestions for exploration/food/etc.
The place was clean, nice, spacious, and most of all well-situated. You might think it being close to a major roadway that it would be loud, but I found the noise to be no issue (although I am used to living with noise in Chicago). Even so, Raffy & Michy were kind enough to leave out earplugs.
From the place you're minutes away from all the Vatican has to offer, and I have to say the two restaurants on either side of the front door are quite good.
I would absolutely recommend this spot.