Great location: 2 mins from subway stop “Lepanto” on the A line. Piazza del Popolo, Vatican City, Castel Sant’Angelo are within walking distance (but there’s also the option to take public transports). Medium-sized supermarket 3 mins away with everything you can possibly need.
The apartment is at the top floor of the building in a wealthy and quiet neighborhood, with many locals and few tourists. Friendly neighbors in the building, no annoying street vendors in the area, no shady people around. Even at night, even on a Saturday night everything was calm and safe. During the day you’ll see many locals going to work/school.
The building has an old-fashioned elevator that I liked (and I think most tourists looking for a step back in time will like) but that can also be frustrating at times. The apartment itself can comfortably suit 4 guests, with two large bedrooms and two bathrooms. Comfortable couch and big table in the living room with fairly large kitchenette.
Federico welcomed me on the first day and explained me everything there was to know. He and his brother were easily reachable and will solve any issue you may have. Super quick check out on the last day (just leave the keys inside and shut the door behind you).
The only negative aspect I have to mention are the vibrations from the subway you may feel once in a while (so not every time it passes) if you are in absolute silence and doing nothing. If you are eating, cooking, talking, or doing anything else you won’t notice them.
I’ll definitely go back next time I’m in Rome.