This is a really nice apartment, furnished in Italian style, in a building with lots of atmosphere. It is very close to everything which needs to be seen - if you are OK with walking then you can walk everywhere easily. For example; Pantheon is less than 10 minutes walk, Imperial Forum less than 15 minutes, St. Peter's about 15 minutes. We did not use public transport at all. Our experience in dealing with Adriana was excellent - she gave advice on good places to eat / drink and gave confidence that she was only a phone call away if we needed her. She arranged a driver to collect us and take us back to the airport and I would recommend this because it is cheaper than a taxi and much more convenient. The apartment is very close to Trastevere (just 5 minutes walk away) which is a very pleasant area to spend an evening eating and drinking and much better than the very touristy Campo de' Fiori.
If you want to avoid some of the more touristy eating/drinking venues, I would advise paying attention to Adriana's recommendations.
I have no hesitation in recommending Adriana's apartment for a wonderful Roman experience.