We loved Mirta's place. It was in a neighborhood about a 10 minute tram ride to Trastavere and 20 to Piazza Venezia (from there most of the major sites are accessible). The tram is at the corner about 1/2 block away and there is a bus stop as well (#14) in front of the apartment building.
We also loved that we could come home to a nice neighborhood where you could find a good restaurant, good coffee, local grocery store across the street, a good local bar, and a short walk to drop off laundry for pick-up the next day!
If leaving Rome by plane, the tram takes about 10 minutes to get to the Trastevere Train station for a 28 minute train ride to FCO Airport for 8 euros. Trains leave every 15 minutes!
We would definitely stay again!
Thank you
Pamela and Eugene