The location of this apartment is really convenient to basically anything you might want to do (it was literally a 5 min walk from the Pantheon). Staying in the Jewish quarter is definitely the way to go. Cynthia and Tatsiana were very helpful in sorting out an issue with our cab driver and really took their time going through everything in the apartment when we arrived. The apartment has pretty much any supplies you could need during your stay. Cynthia is very quick to respond via the app to help with any issues or questions you have - she really goes above and beyond.
A couple of things to note about the apartment. Because it's in a very central location, there is a lot of noise outside both day and night, which of course is outside the host's control. The tram squeals around the corner of the building, there are people yelling at 2 or 3 am, ambulance sirens every night, and the neighbor starts playing music very loudly late at night (Cynthia asks that you text her if you need him to turn it off; she calls him and then he does turn it off). Some people can sleep through this, but we didn't get a proper night of sleep a single night out of the week we were there.
It does have an elevator, but you have to climb two sets of stairs before you reach the elevator that takes you up to the 4th floor - just something to note if you're coming with heavy luggage.
Another thing is that the apartment is listed as 2 bedrooms, 2 baths, but it's actually a 1 bedroom, 1.5 bath. There are 2 beds - one in the bedroom and one in the living room, but if you have someone sleeping on the bed in the living room, there's really no common area to hang out in. The bedroom is a loft - I'm 5'8" and couldn't stand up straight in it. The half bathroom (toilet and sink) attached to the bedroom is extremely tiny - just something to be aware of if you're tall.