You can't get more central in rome than this place. It's a block away from the Pantheon and within 5 minute walk to restaurants, bars, gelato, pharmacy, grocery store and taxi cab stop.
The place is very large and nicely laid out for maximum privacy. We had 4 people in our group and were very comfortable. The place has a few quirks like odd keys and a downstairs restaurant that can be loud at night. But that is part of the experience of visiting Rome.
Dario was an excellent host. He was super communicative and followed up to make sure we were all comfortable.
I'd definitely look to stay here again if I get back to Rome.