For our Trip to Rome this was the perfect location! The Vatican is around the corner and the apartment is more than beautiful - plus the host, Valentina, is very engaged and open minded. She answers very fast and is very keen to help, if it's needed. She welcomed us personally, showed us the main things of the flat and gave use the best insider advice where to go (e.g. restaurants, bars..)
Our tip for everyone, who wants to go there: Use the metro to the station "Ottaviano", so you can drive from the Main Station (Termini) to the flat in around 15-20 Minutes ;)