We loved staying at Vatican loft. It has a good location, very close to metro so it’s only a few minutes to Piazza di Spagna or Fontana di Trevi. It’s also 10 min walk to Vatican museums.
It’s very good neighborhood, with bars, restaurants and pasticcerie (we recommend La Sicilliana!)
Giulia is a great host, she explained everything when we arrived and even helped us find taxi when we were leaving.