Anna and her daughter were lovely hosts, really friendly and helpful but happy to give us our space as well. The apartment is gorgeous, with lots of character and great art, very clean, and in the perfect location for us. We're quite keen walkers (we averaged 30,000 steps a day during our stay!) so for us, both the Vatican and the Colosseum were within walking distance (about 20-30 mins away each), but there are also trams and buses which go directly, and the Trastevere area itself is also great - there was an open air theatre nearby and lots of cafes, restaurants and bars offering aperitivo in the evening. Can't recommend highly enough!