We had a great stay here for our visit to Rome.
The neighborhood is quiet in general, with the occasional construction, but they keep it to daylight hours, so no worries about sleep. There's a great little cafe just a few steps down the street called Retourner, excellent sandwiches and pastries, and lots of drink selections. Several options to grab a public bus about 5 minutes walk that will get you where you need to go. The home is on a slight hill, so keep that in mind when planning adventures. But it'll help walk off all the great food you'll have downtown.
Lots of other local shops and restaurants within a few minutes walk as well.
Leonardo is a great host, very welcoming, and attentive. The space is also nice, everything you could need for a stay.
We would definitely stay here again when visiting Rome!