Anna's place was amazing! It was literally next to the Vatican. It's not as central, but the bus is right in front. Check in was smooth and any questions we had, Anna responded immediately (even at night-Sorry Anna!). She left us a map of places to eat at and even a bottle of wine. The place has two bedrooms and baths and a cute outside patio. This place was even better than the photos. Definitely recommend this place.
Thanks Anna!