Close to the Vatican (walking distance) and there is a metro stop right outside of the place for fast travel to all the tourist spots you'd want to go. We didn't have any trouble getting anywhere. The 24/7 store next door was fantastic, helped us save a lot of money by buying a simple meal to cook for breakfast or a small dinner. The elevator has a 400 pound weight limit which for us did not work. I'm a bit on the heavy side lol. Great place would recommend!! Bring your own towels, there was only two provided!