Domus Navona was a wonderful stay on our trip in Italy. The flat was spacious and the most comfortable we had in the four cities we visited. What helped was the fact they put a 2 inch memory foam cushion on top of the mattress. Italians love hard mattresses and this cushion helped a lot with making the bed more comfortable.
Domus was warm and welcoming. While it was up several flights of stairs, there was a small elevator that got us there quickly. The neighborhood was quiet with a couple of local shops and restaurants nearby.
It was centered in Rome near all the major attractions so walking wasn't too much of an issue. Be it going down the street to the Pantheon or taking a 15 minute walk up the street to the Colosseum.
A good sized grocery store was located just down the street from us and the flat had both a washer and a dryer for handling small loads. My biggest complaint was the lack on instructions on how to use the washer or the fact that the dryer has a water container that must be emptied occasionally. We left written instructions for the next guest on how to use the washer. Just remember to check the bottom panel of the dryer, at the bottom of the unit is a removable bottle of waste water that must be emptied.
Other than that, it was a VERY pleasant stay and I highly recommend Domus Navona to anyone that is staying in Rome.