Location location location! As far as finding a central place in Rome is concerned, you can't do better than the Pantheon Domus Valentino apartment. Literally a stone throw from the Pantheon, which means that a lot of Rome's major sites are an easy stroll away. This central location is simply fantastic, not just for the sites, but also for an endless choice of restaurants, gelaterie, coffee places (tazza d'oro is literally just around the corner), you name it.
But it doesn't stop there. The apartment is clean, modern and has everything you need. The noise from outside disappears when you close the windows, the air conditioning is modern, quiet and very effective. The shower is great, wifi is excellent and the owner, Fabio, even left an iPad in the apartment for us to use should we need to.
As for the host, he was extremely helpful, offered to pick us up from the airport to save us the hassle of public transport, gave us loads of tips for good places to eat and where to get the best coffee and was warm and welcoming. Needless to say, our long weekend in Rome was a success and next time we visit, I hope we'll find this place available. No brainer.