Martina was waiting for us at the front gate as we checked in, and she thoroughly explained everything we'd need to know for a great stay. She remained available via text, and made some tasty restaurant suggestions (we can vouch for Rossopomodoro, which is a nice stroll away from the apartment!).
The street has a several restaurants and cafes that are not overpriced, like the city center ;).
Depending on where you want to go, it will take you about 25-45 minutes to reach it via public transport (closer to the Vatican, further to the Colosseum).
Be sure to check out the rooftop view, and if you have more time, take a chair up there and a drink to enjoy as well :).