We spent four days in Manuela's nice apartment. The apartment is close to the Vatican in an adorable little local environment with good restaurants and bars.
The apartment has everything you need and is neat and clean. It is close to the Metro and good bus links to the sights of Rome, but outside the "touristhell".
Manuela is a fantastic host, helpful and informative with a high level of communication.
The apartment and Manuela get our very best recommendations.