Having lived in Rome for one year, I had priorities for where to stay with regard to what I like to do. I love the Gionocolo and Monteverde. Luigi and Maria Pia's door is just outside the entrance to the Parco di Villa Pamphili. This is a favorite spot for me as a runner, but even for those who aren't runners, I recommend spending time in the park and walking to the Villa. Along with sweeping views under the Stone Pines, you'll find rusticated seventeenth century ruins, exquisite fountains, a grotto, and the magnificent villa surrounded by a sculpted hedge maze. Although they were built to look like antique ruins, age, neglect and damage have added mystery to the sculptures that emerge from forests and stone.
Being situated on the hill, Luigi and Maria Pia's place can offer exercise for those who enjoy it; but if you simply want to be away from the noise and commercialism of the Centro Storico, it is easy to take a taxi or public transportation.
You'll find kind, friendly hosts who communicate quickly and thoroughly, a comfortable and sparkling clean room and bath, a thoughtfully prepared breakfast, and the world's nicest dog, Marilyn. I highly recommend this accommodation and would stay again.