This place is very close to the Roma Termini station - about 5 minutes walk. We were a family of four with two kids and it was an easy walk to this place from the station. As others have noted the suite is on the ground floor (1st floor in US) but check in is on the 5th floor at Hotel Marcantonio. It took a bit of asking around to figure out where to check in. But once I was at there I was greeted by Lauro who was very warm and friendly. We had arrived almost 3 hours earlier than the check-in time and Lauro was very accommodating and had the housekeeping prioritize our suite and got it ready in an hour. In the mean time he helped put our luggage in storage.
The place is very spacious, sparkling clean, wifi worked great. Having two bathrooms was really helpful (although the shower in one of them wasnt working but it really didnt impact us). We had an early morning flight the next day and they even had breakfast packed for take-away!
Overall we had a very comfortable stay and it was a good experience with Lauro and Simona.