Lorenzo's place was fantastic for our recent stay in Rome. It is very centrally located, right in the Jewish Quarter, but also close to the major tourist sites. We walked everywhere from the Vatican to the Colosseum, and only used taxis for one out-of-town dinner and getting to and from the airport. The place itself was gorgeous, extremely well furnished, and it was great to have a kitchen for morning espresso and breakfast. As some other reviews mentioned, the shower and toilet room has a particular odor, but air freshener was provided and between opening the window and closing the door, it wasn't bad at all.
The space was always very warm and inviting - very nice to come back to for an afternoon nap or to retire for the evening. I would highly recommend for anyone looking to explore the city and have a wonderful place to relax afterwards.