We stayed for two weeks as a family of 5 (3 young kids). It worked well for us. Good location. It is close to the Orange Grove, one of Rome's best views and parks.
Quiet neighborhood, apart from weekly concerts at the Circus Maximus (but these wrapped up relatively early).
The only thing we would have liked to add is screens on the windows. I know this isn't very common in Italy! No screens meant we used air conditioning more than we would have otherwise, since we were keeping the windows closed.
I can imagine some groups might find the fact that the bathroom is entered through one of the bedrooms inconvenient. For us, no problem.
We would recommend it.