Casa Clodio was perfect for our stay in Rome. It really is cosi and comfortable, clean, and has everything we needed. We met Gabriele once, when we arrived, he was very helpful and gave us some fresh fruit, water and pasta for welcoming gift. The neighborhood was clean and not crowded, and very near to Vatican, 10 minutes by foot. You can go to the city very easily by bus, the bus stop is right there in the front of the apartment. Also we went to the city by foot once, to piazza Popolo, then Trevi Fountain. But I didn't recommend to go to the city by foot every day, specially in the summer :).
The apartment also has wifi connection which is really fast and useable, if you need it.
The street where the place is, has a lot of restaurants, some mini market and also a wine store. There is a carrefour express one block away, and some bigger stores 10-12 minutes away, you can easily find them with google maps.
We'll really recommend the place for anyone.