We had a wonderful stay in B&B Domus Aurea, which is in a quiet street with a small park to stroll through to get to the Coliseum, metro, trams and buses. Fantastic location!
The bed was comfortable, the room spotless (cleaned daily) with lovely high ceilings and the bedroom window opening onto the little courtyard garden. Breakfast was good coffee, home baked cakes, toast, hard boiled eggs, fruit, yogurt and cereal, mostly local organic produce. For a small extra charge we were picked up and dropped off at the city airport, which made it very easy for us. Highly recommended.