Our stay at Flavia's Airbnb was great. Her place is in a great location for seeing all the major sights. it is right next to the metro to easily get to areas of Rome with the tourist sighs, but it is separated enough from the tourist areas to avoid the crowds. The Prati neighborhood has a nice local vibe with great restaurants and shops.
One word of caution - the steps up to the loft area are steep. It wasn't a problem for us. But, if you have balance or mobility issues then you should be very careful.