Antonio's apartment is near the Vatican, but the walk to St Peter's is about 25 mins... including many steps/uphill. It is near buses and Metro, grocery stores and many restaurants.
Antonio very kindly answered all my questions quickly. There may have been a couple of communication gaps (language). He offered to book a car service to pick us up upon arriving by train, but the driver came with the wrong size car, was unclear about where to meet, and ended up having my husband and son take the metro, but we were still charged the same fare. The whole ordeal of finding the driver and then getting a car took over an hour. He also told me they would take credit card but the driver insisted on cash. The car service does not provide contact info so I had to go thru Antonio to communicate - while it seemed like a good idea at first, turned out to be a hassle. I would skip this and make your own arrangements or take public transport.
Elevator is great for bringing luggage up and down, though the rest of the time, it was not bad to walk the stairs. The apt has basic furniture and kitchenware (no bowls, and most importantly, no corkscrew!!!) There were just a few glasses. Toiletries are just big bottles, not individually sealed. There was one roll of toilet paper per bathroom (which I asked about based on previous reviews, so we brought our own extra). The good thing is the air conditioners work great and silently! Two bathrooms are hard to find and a definite bonus with more than 2-3 people. The rooms are all pretty big and one bedroom and living room have doors that open to terraces where there are 2 chairs if you wish to sit outside. The outer gate downstairs seems to have a lock problem. Our key bent, and a quick message to Antonio a few minutes later, he had his colleague bring another. Bedroom 1 is listed as having a queen and a single bed but the single bed is actually in the entryway right next to the door. The beds were all comfortable, as well as the sofa bed.