The location is good. There are bus stops and the metro close by. The metro takes you straight to vatican city in like 20 mins. The colloseum is about a 30 min walk. The apartment itself is small and cozy. David( host) was very responsive in any questions we had. You need a key to enter building as well.. so it felt pretty safe. We would get back around dark and never felt unsafe walking around the area. Plenty of resturants, coffee shops, and gelato around. Only complaint is no hot water on last day( but since we were leaving it was not a big deal).