Perfect room right in Old Trastevere! I lived right around the corner a few years back for 4 months and can vouch that it’s a great area. I was traveling solo in Rome and my stay felt very homey because the hosts were so great. They met me in person for check in to show me how to use the keys and they had lots of little details in the room that made me feel comfortable - to name a few: a mini fridge with a few drinks, some snacks and tea, charging converter, earplugs, towels, a hair dryer, and even a little bottle of Prosecco as a welcome gift. They gave me advice about what time I should leave for the airport and were very kind overall.
About the area: Right near the best restaurants / cobblestone streets of Trastevere, a close walk to Campo de’ Fiori and the Pantheon, and right by a really convenient tram and bus stop. If you have to get to Fiumicino airport from there, you can simply take the tram to Roma Trastevere train station and then the Leonardo Express will take you straight to the airport for only 8 euros. The hosts are very kind and would likely offer any advice or directions.