This is a good place, particularly if you are going to be spending a lot of time in and around the Vatican. It is a short and beautiful walk to the Vatican and to the Tiber, and feels quite safe at any time of day. The guidebooks and maps in the apartment were useful even after I had spent considerable time planning our visit, and the hosts were accommodating in allowing us to check in early at 11am. It is some distance from the metro stops (25-30 minute walk) so if carrying luggage it will be worth calling a taxi. The host offered help booking transport services, which we did not take advantage of but it was a nice touch.
The apartment is as advertised and offers a good value. Considering the extra cleaning fee, the only issues we had were: I would have hoped for better maintenance (the bathroom door did not fully close during our stay and the washer sputters water) and one or two more domestic supplies (there was only one washer soap pod and no paper towels). Overall, for the price and location it was a good experience.