The closeness to the colosseum is great but trying to sleep is difficult as the bars near by make a lot of noise late at night. Make sure you take some good earbuds!!
The whole house smells like a smokers house, we bought an air freshener and not even that helped much.
The good thing is that rooms have their own AC unit which kept the house nice and cool. Try not to open the windows as Rome has some very feisty mosquitos.
The electricity of the house went out twice and we had to go to the break room on the first floor to reset the breaker. Besides that the beds were comfy and the house was clean.