Jane can help you with transfer from airport till the apartment. Till the Vatican is about 10 minutes to go and 7 till the metro, however we walked all time, since everything located really close. In the flat you may find all what is needed for your comfort, however the wi fi is really poor. Also, think in advance if you need a supermarket, since they close around 7pm, but the nearest one is also about 10 min to go, nevertheless there are some restaurants not far away from the apartment.