We liked staying in an area that wasn't full of tourists. It was a long walk to get to the more historical sites but the bus system was straightforward to use when using online maps -- gave you specific information about what busses to take. We liked being in close walking distance to Trastevere, a great place for dining. The Tiber River was just a half block away and my wife enjoyed running along the path a couple of times. I took a Lime scooter on the path as well, which was a lot of fun. Had a great meal across the street at MaSandro Ristorante Pizzeria on our last night.