Sandra's place was an absolute gem! There were 4 of us in the group (two couples) and the 2 bedroom/2 bathroom scenario was perfect! The apartment was very comfortable and very well situated. Just a few minutes to the Vatican, and a 2 minute walk to the closest metro (which is easy to navigate). Additionally, down the street, there is a grocery store, bread shoppe, and lots of cafés, so it was easy to stock up on a few things for afternoon snacks/breakfast in case you wanted to save a few euro by eating at home. Sandro gave us a printout of the way to get around, as well as restaurant recommendations, and was overall very helpful!
A bonus was having a washing machine- we were able to wash out clothes and hang out to dry easily, which made life a lot easier than having to find a laundry facility.
A few things to note about the property:
1. The apartment does not have air conditioning. It was relatively hot while we were there, and while opening the windows and using the fans Sandro provided helped considerably, it was still very warm. We were staying in the room off of the Main Street, and so opening the window meant hearing everything going on, which is a lot, late into the night and early in the morning. Coming from city living ourselves, this wasn't a big problem for my husband and me, but something to consider.
2. The area, as expected, was not as bustling as say, Centro Storico. We liked this because it made it easier to relax. However, keep that in mind because after coming back later in the night, the roads are relatively empty, and some of the restaurants closed relatively early (like 10/10:30 as opposed to later).
Overall, a wonderful stay!
P.S. My husband and I took the bus to the Vatican instead of a cab from the airport. This took us only about 30-35 minutes, and dropped us off north of Castel Sant'Angelo, which was maybe a 7-8 minute walk to the apartment. The bus was 6 euros per person vs. nearly 50 euro to take a cab :)