We loved the decor and how spacious the apartment was, everything we needed was there, it was great! It was very clean and the security of the entrance was a plus for us. While it is a walk to all the major sights, we did enjoy it as we took a different turn every time and discovered different things, and the exercise also helped to keep off the weight after eating all the food and gelati!! There's a bus stop at Piazza Fiume which will take you to a stop close to Vatican City, then it is just a short walk. If you wanted to catch a taxi, there is a taxi rank at Piazza Fiume as well. It was close to walk to termini station which was good for us as we took a couple of day trips to other places.
There are heaps of restaurants around too, Ristorante Checco e Lina was the best! And lets not forget about the gelati, Gelateria La Romana is the best! A couple of great coffee shops / bakeries are nearby too, we loved our neighbourhood bar/coffee across the road, which we would stop in to have our quick macchiato to start the day. A great bakery is La Gioia del Pane which had delicious pizzas to grab and go. There is also a supermarket around the corner.