Location, location, location! We did use the airport transfers arranged by Giacomo but once we were there we walked everywhere except for one subway ride to the Vatican (and then we walked back) The streets are just too interesting and so much was close by. Gelato was a requirement for my kids and we tried a different place every evening. The back bedroom is the darkest and quietest. Kids were in the front rooms and slept fine. Grocery store is less than 2 minutes away.