A nice apartment just a few minutes walk from the Vatican. Shops, including a great deli, restaurants and a great gelataria are even closer. The Cipro metro station is a few minutes walk but most of the main historical locations are not much more than 30 minutes walk. The apartment doesn't have a good seating area for relaxing in the evening so don't plan to spend too much time indoors (but why would you!). Four people would seem a reasonable maximum occupancy.