We really enjoyed our stay at Irene's apartment last week in Rome. We did not meet Irene, but Menella was great at getting us set up. We were VERY late due to a late plane arrival, but I kept Menella up to date and she gladly stayed and got us settled in.
We are a family of 4 and had enough space for the little amount of time we were in the apartment. The apartment is just a couple of blocks from the Colosseum and not far from a metro as well. We were just a block away from the main street of Monti, but it was very quiet in the evenings.
Would recommend staying at Irene's apartment when visiting Rome!