Reliable host, very big appartment with everything you need. Walking distance to Aventino Hill, Circus Maksimus, Palatino Hill, Roman Forum and Colloseum. You have buses (1,5 €) for 100 consecutive minutes to take you everywhere (bus 715, 716 stops just 20m from appartment- tickets at the kiosk). There are shops all around just on the same street as well as Eataly and small Ikea.
For tourists I recommend to avoid to big cue to visit 2 km away Palatino Hill entrance to buy ticket (for PALATINE/FORUM and COLLOSEUM for only 12 € ). For Coloseum you get an hour when you can enter and take the much shorter line for entrance with ticket. Palatine/Forum can be visited also the next day.
And do not forget to explore the northern part of Rome as well. Recommendable with bus.
For cars - if you arrive in the morning it is not hard to find a free parking just on the street by the entrance.