I have been to Rome many times; it can be a noisy place, especially the ambulances. Because I have been to Rome many times, I wanted a place where I could relax or wander the sites if I chose to. The Borgo neighborhood is not in the center of Rome's nightlife, but a cab station is around the corner. There is also a nearby street where many busses stop that can take you anywhere in the city. I enjoy walking the few minutes to St Peter's Basilica in the early morning or late evening. Visit the basilica about an hour before closing. The crowds will be gone, and it will only take a few minutes to go through security.
I loved my stay at Claudia's and know you will too.