While I enjoyed Rome, I really enjoyed the comforts of Dario's B&B. It was very comfortable, spacious and homey! He even allowed me to leave my luggage for quite some time until I was done with my ventures. I would stay here again.
The place was hard to find at first but there is bus 51 which drops right outside and its near the St Giovanni Metro which can be a bit of walk if you have a lot of luggage.