We really enjoyed our stay at Paola's Casa Oddo. It was centrally located, halfway between the Colosseum and Vatican. Other top sights were extremely close-by. Plenty of cafés within minutes walking distance. Everything could be walked to, but if not up for it, taxis are very reasonable. The apt was very spacious, cozy, clean and tidy. Loved the neighborhood and it's everyday rhythms, including a little grocery market and coffee shop/bar right across the street. Paola was a very friendly host and check-in/check-out went very smoothly. I would stay there again if ever in Rome!