If you’re going to Rome, look no further, this is definitely where you should stay. Why?
The atmosphere in Campo de Fiori is amazing. It’s bustling with a cute market, it has plenty of restaurants, gelaterias (you have to try frigidarium), bakeries, nightlife, etc.
Location wise, you’ll probably want to take a taxi or private transfer from the airport. But after that initial transportation expense, it’s very reasonable to walk everywhere. For example, it’s about 25-30 minutes to the colosseo and the Vatican. Also about 10 mins from the pantheon, plus the Trevi fountain and the Spanish steps are not much further.
Also a mention that the hosts were more than accommodating in letting us drop off our luggage earlier than our checkin. Amazing!
On a side note, take what people are saying about the stairs to heart. It’s a very steep climb and it is difficult with suitcases. If you/or someone else is not able to lift your suitcase, I think it’d be very difficult.
If I come back to Rome, I’d love to stay here again!