Alexio is a great host with a lovely apartment in the heart of Trastevere close to all the action yet secluded enough for your peace and quiet. His suggestions for places to eat around town were excellent and we felt that the Pistachio Gelato at Gelateria dei Gracchi was the best we had in Rome!
The apartment is close to public transport and you could be in Vatican or Colosseo within 20 minutes by bus/tram or 30-35 mins walking.
The apartment itself is an older one (in keeping with the neighbourhood) with a spacious layout. As long as you are OK with the slightly older look & feel, Alexio's place is a great one!