Daniela made us feel extremely welcome in her B&B. Every morning she brought us breakfast and fresh coffee if we wanted it and every evening we came back to a lovely clean room and fresh made bed.
Because of the day we arrived (Saint Stephens day) we had trouble finding transport to Daniela's house, and even though we were late she waited up for us and told us not to worry. When we arrived she even recommended places we could get food before going to bed and gave us a map.
Daniela is a really lovely woman and she keeps her B&B extremely clean. It is about a 7 minute walk to a metro station and from there you can get a 15 minute metro to the main termini and go on to any of the main tourist spots (metro tickets are very cheap so this method is excellent for seeing everything without waiting for buses). The B&B is also just a 15 minute walk to the vatican city.
I would highly recommend Danielas place, not only for comfort and location but for Daniela herself, she is a lovely woman who does everything she can to make you feel at home.