Emanuela's guesthouse couldn't be more perfect for staying near the Rome Termini. It's only one block away from the station so extremely easy to get to at any time of day, and it had virtually everything we needed to sleep and stay comfortably. Her husband Antonio met us and was very friendly and kind, and they are very attentive to guest safety as far as a lock on the door to the suite of 3 rooms and then each room itself (as well as the lock to get into the building). The common area was very spacious and had any amenity needed, and of course air conditioning and the elevator (super tiny but works!) were a major plus. Also there are non-stop trains to get from the station to the airport so it could not have been easier to get to the airport by 6:30AM for a 9:30 flight. The last time we stayed in Rome overnight before heading home from Europe I booked a room near the airport, thinking that would be the most convenient. But now we know that Emanuela's guesthouse is definitely the preferable solution. (Not just for convenience to the airport but also because it was super easy to take an Uber from it into the city for a few hours around the Trevi Fountain/Spanish Steps.) We will definitely be back to Emanuela's if we travel out of Rome again!