Gaia's place is perfectly located for your trip to Rome. We walked EVERYWHERE from her place, but if need be, metro is very close by. Vatican is right around the corner. It's about a 30 min walk away from the Colosseum and other main attractions, but this actually plays into your favour as Rome is very busy and hectic. We lucked out and felt much safer and enjoyed our stay much more being slightly outside of the main touristy stuff. Plus, we got the "locals" experience which is far more important. Gaia was a fantastic host and we absolutely loved our stay in Rome. Couldn't ask for anything more from her.