The location is ideal for your Rome / Vatican vacation. The regional train across the street makes getting to the Airbnb from Leonardo da Vinci International Airport or Roma Termini station easy (except for a 6 AM flight).
The host provides wonderful local recommendations. Also, feel free to book the Breakfast Vatican museum tour because you are only a ten-minute walk away.
The Airbnb is large enough for a full family or three couples to travel comfortably. Additionally, I appreciated the host provides two sets of keys so while exploring Rome you are not tied to all traveling companions.