Lorenzo's apartment is 15 mins by walk from the Rome termini station. He suggested me to walk it down but it was a real pain carrying the luggage along cobbled roads. I suggest you should cab it down if you have luggage. Otherwise, the location is good. The colosseum is a 7-8 min walk. The main streets are around and easily accessible. Lorenzo was waiting outside the apartment to receive us and helped with the luggage. He provided with a map of Rome and with some basic information. Overall had a good stay.