Fantastic location, on the opposite corner of the Spanish Steps in Piazza di Spagna. Short 3 min walk from Spagna metro station, smack in the middle of the Spagna designer shopping district (Prada, etc). Great for access to public transport. Lots of decent boutique restaurants, pharmacies, tabacchis (smoke shops), convenience stores in the adjoining street.
There aren't many cafes in the immediate area, nor do they open early (usually 9+AM) since they cater to the shopping crowd. There was the random drunk patron at 1AM (noted by other reviewers), but it was a one-off instance for us and was otherwise relatively quiet at night. Facilities are a little dated, but within expectations for the location. Apartment is on 2nd floor about 25-30 steps up, not a difficult climb for aged parents.