This is a wonderful wonderful place to stay if you are doing a short stint in Rome! It's only a few minutes walk from St. Peter's Basilica and and Vatican City. It's also close to the metro station and bus line. We stayed for three nights, and used the city bus (64) to get to all the monuments. A bus stop is just outside Gianluca's apartment and the other lines all pick up just a few minutes down the street. Gianluca is so welcoming, friendly, and so accommodating. He lives just up the street from us so it was easy to ask for help if necessary. He provided us some coupons and complimentary things so that we could get a nice feel for the neighborhood. There were so many amenities available (even a printer in case you have to print out tickets!) in his modern apartamento, we never wanted for anything! The neighborhood was quiet and conveniently close to a lot of restaurants. The only thing I can even complain slightly about is that the shower is a bit tricky when it comes to keeping the temperature steady, but I'm sure it was just us.
If you're coming from the airport and have a lot of luggage, you can take a taxi arranged by Gianluca to get to the house. It'll help you worry less about logistics in a new place if you've never used the metro system. Then you can learn while sightseeing and take public transport on your way back. We have already tried to book with Gianluca again for a return stay but his place is just so popular it was already snapped up! I am sure we will return some day :)