We (young German couple) loved to stay at Monica's great apartment! It's in the Jewish Gettho, right next to the historic center of Rome. Nearby are lots of historic attractions and plenty restaurants. You can nearly visit all the great monuments by foot (Roman Forum, Colloseum, Pantheon, Trevi fountain, ...). Just for visiting the Vatican and Castel S. Angelo we used the bus. So I can highly recommend a stay at this wonderful place.