Amazing location if you're looking to walk to historical sites easily, be in the center of the nightlife, have tons of food options surrounding you from the moment you step out the main door (although most have the exact same items, of different qualities) and be helped by an awesome host.
My husband broke his foot a few months ago and is still recovering from his injuries so like other reviewers said, Lorenzo helping bring luggage up was incredibly helpful on such a ridiculously hot and humid day. The place was so clean (hotel quality) and comfy. We only slept in the "main" bedroom but the bed and pillows were fantastic. We had stayed in a few places in Italy who had questionable cleanliness so it was greatly appreciated. Bathroom, kitchen and living room were exactly what we hoped for. Definitely enough room for 4 people even though it was only 2 of us who stayed there.
The stairs are definitely not the easiest to deal with (we knew this when booking) but the location and accommodations make up for it 100%, and checking out and going DOWN the stairs was a breeze =)