Although this was our first time staying in Rome, I wish our experience was better.
Every single night the bar across the small street played loud music from 10pm through 4am. We enjoy going to bed early and wake up early to avoid crowds at main attractions. There are sound proof Windows, but it only does so much. The walls are thin so it allows the music to come through. When we first brought it up the host he just seemed to shrug it off asked to collect the city tax for staying in Rome. We also emailed him a few days later and the response we received just didn't make us feel any better.
Yes, we stayed inside the heart of Rome, but having music going until 4am is just a horrible experience.
If you enjoy going out late at night and more of a party person then sure this apartment is for you.
Location: Everything can easily be walked to. You really don't need to take a taxi or even get a bus pass. At most it's all within 15 minutes, expect the colosseum is about a 30 minute walk which is decent.
Again, if you value your sleep just like us on vacation this perhaps this place might not be for you.