This home is pretty far removed from the hustle and bustle of central Rome. It is in fact located in a quiet neighbourhood a little more to the east. That is not to say it's not well connected via public transport, it's only a quick tram ride to the termini station (a central station wherein you can catch the metro or a bus or a train to anywhere) but the charm of this place is the restaurants and shops that are scattered around it and the different overall feeling from a more centralized location; my wife and I split our time in Rome at two different Airbnb's, one right by Vatican City and this one. Our hosts explained that it was originally a working class neighbourhood but it's starting to burgeon as a community for young families and it definitely shows; it's quiet and it's quaint.
Even though we visited during a colder part of the year and we weren't able to utilize it, Alessandro has a wonderful yard that would be lovely to enjoy during the warmer months.
The hosts themselves were very kind and welcoming. Roberta received us with a nice cup of coffee and homemade biscotti while Alessandro was able to answer and and all my questions!
It was a very positive experience staying here and I highly recommend their place to anyone visiting Rome.