Nicolo's place was absolutely amazing! It was much larger than expected and was outrageously clean and my kids kept telling me how much they liked the fast wi-fi. My favorite part of the home was its proximity to the Vatican and every night coming home with a view of the city. If we ever come back, I would strongly recommend staying here.
Evidently there is a 'head tax' so be aware that you'll have to pay five euros per day per person in cash in addition to the Airbnb fees so add this to your estimated budget.
One last thing, two doors down is an amazing cafe where you can get a great cup of espresso for just over a euro. My wife and I went down there every day and just soaked in the experience enjoying the great coffee.