I had ( Eva) a Perfect experience at Marzia's place! Is right by the Vatican and you can see it from the window! Pretty amazing!,
The area is safe and I walked to all the places. But you can definitely use the bus and taxis( I took some cabs actually and was always around 8 €). I arrived and left by train which was very convenient since she is blocks away from the station( forgot the name). The room is lovely. Very clean, beautiful and harmonious. It was a pleasure getting there after a long day. The bed is super comfortable. The shower fantastic. There are Rome guides in the shelves which was very useful. The entrance to the room is independent from the rest of the apartment which I thought it was cool. Everything better than expected. I loved it. Marzia is just an amazing host. I entered her place as a guest and left as a friend. Lovely. Thank you very much Marzia!.
P.S: for the Vatican visit I highly suggest to use the company " dark Vatican tour". It's fantastic. Smart, young and knowledgable guides. Very dynamic and exiting, fun :)