The house is very close the the University of Rome, so there is a really cool student vibe to the neighborhood. The vibe on weekend nights was very similar to that of Bologna or other italian student areas: everyone is out drinking in the squares with music and a really lively atmosphere. There is a 24 hour supermarket near by which we found really useful. There were plenty of options for dinner that are around 10 euros for a main dish with more than enough food.
It's about a 20 minute walk to the Coloseum with a lovely park to relax in before you arrive there. There is a stop for bus 71 two blocks away that takes you directly to Termini in a couple minutes (otherwise a 15 minute walk). From there you can take the metro or bus to any other place you want to go. That being said, the city is very walkable if you have the right shoes.
The flat is perfect for a couple (as was the case with my boyfriend and I), and comes equipped with all the cooking essentials. I am seeing a lot of complaints about the shower on the reviews here, but honestly isn't that big of a deal. There is a washer right outside the door you could set your toiletries on so you don't have to bend over to grab things.
Ludovica was very accommodating with our check in as details about our specific arrival time kept changing with flight difficulties. Overall, it was a lovely experience, and I can highly recommend a stay at this flat.