The central location is within easy walking distance of literally everything -- the port, the shopping on Via Toledo, the wonderful restaurants in Centro Storico, the National Museum, the Circumvesuviana -- everything.
As we stayed here in summer, we really really really appreciated that there were air conditioners in the bedrooms. Do note that the second bedroom is up a small flight of stairs. My two boys slept there.
The kitchen is big enough to sit and enjoy a coffee in the morning and has a sweet patio out its door and the beds were comfortable.
We would definitely stay here again.