We spent three nights in Naples and had a generally good experience here.

Positives:
--the unit is recently renovated and has a lot of natural light. The The bedrooms are loft-style, so if you have a hard time with stairs, this is not the unit for you. However, we found it to be generally good, even with moving the baby up and down the stairs. There is an old lift that moves you up and down which doesn't have too much space in it, but i think it helped highlight some of the original character of the building.
--There is a grocery (Carrefour express) a few blocks away that allows you to get most items you need. You are also a few blocks away from the metro and a taxi stand is across the main street (by the hotel), so transportation options are very accessible.
--Manuela and her sister had a great collection of books for adults and toys for kids. They were even kind enough to set up a baby cot for us before we arrived. They also greeted us with the famous Sfogliatele dessert that Naples is known for.

Negatives:
--wifi was a big issue here initially. The wifi isn't actually in the unit, but rather is shared with the unit next door. As a result, the signal only works in a small section of the apartment. if having wifi access is critical, this would be an issue, but if it is not critical, they you might not notice this problem too much. We did let manuela know about the issue and she did point out that there is also a wired connection you can use in the unit too, but this again only is in the upper bedroom.
--Naples is a gritty city to begin with and this is probably one of the safer areas given that you are right across from the university. Being from New York which has similar areas, I didn't feel too uncomfortable, but the area didn't necessarily feel like one you'd be wanting to walk around alone at night in.
--the unit is part of an apartment complex and has a balcony that doesn't have the prettiest view (it looks down onto an alumnium room and is surrounded by the balconies of other units and outdoor clotheslines for those units). The floors and walls didn't really block out too much sound.
--Not having air conditioning was a negative because the neighborhoods were too loud at times to leave the window open (at least for our baby) and there were a couple of mosquitos that would get it too.