Casa Salazar is a beautiful, modern and very tastefully renovated apartment (Demetrio is an architect) in an old Palazzo with high ceilings and lots of space, every comfort and fancy details. It is very nice to stay there and relax from the hustle of the city. It is located quite far from the centro storico ( it takes about 30 min. to walk to the center of the restaurant and shopping district Chiaia), but the train/metro station is just one minute away. Within two metro stops you get near the main shopping road Toledo (Montesanto) and within three stops (Dante) to the centro storico. The neighbourhood of Mergellina is good, with some very nice restaurants and you are at the lungomare in just about 7 minutes walking.
If you are travelling by car, the location is very convenient, as it is easy to reach from the autostrada and there is a parking in front of the apartment for the arrival (when the gate of the palazzo is open, you can even drive in the court to drop the luggage) and a garage within 3 minutes walking, where you can leave the car safely during your stay (20 euros per 24 hours).
Another plus: If you plan to visit Pompeji, its perfect by direct train from Mergellina (to Salerno, not the circumvesuviana to Sorrento! ) because you can avoid the tourist crowds at the main entrance and get to the site at the entrance of anfiteatro (7 Minutes walking from train station).