Lovely old converted distillery building right in the centre of the historic city. Lots of cafes, bars and restaurants in the locality and close to the main shopping area just down from Stroget; you can walk the whole city from there.
The house was perfect for our large family group with a large kitchen/dining/living space with a big table for family meals.
You do need to be prepared for the fact that being a tall building there are a lot of stairs.