We can confirm everything that has already been mentioned in the previous reviews:
We came to Maria's Anatolia Villa end of september/begin of october and at this time it was absolutely quiet.
Maria gave us a very warm welcome, explained everything and everything was heartly prepared for us; she was always reachable for questions and suggestions.
The villa was fully equipped, nothing was missing, cold Beers and a tiny ouzo bootle awaited us and Maria even organized the typical 'Briki' and Greek coffe for us - fantastic! Everything was absolutely clean and in very good condition, Wifi worked perfectly well and fast.
You reach the house via small path by car, no noise from the street and the ground is spacious, and you have a fantastic view.
The Villa Anatolia is typical greek style but modern. You can see the Sunrise from the Veranda and, as well, from the window in the sleeping room.
Still we found open tavernas and small mini-markets nearby.
It is uphill from the beach, and, as we had a rent-a-car, we went down to the tavernas by car (~1 Min) and to the main golden sandy beach (~1,5 Min).
We can highly recommend Maria and the cottage, as well as Karpathos fantastic beaches.
Small hint:
The location of Amoopi is perfect for island excursions.
And, you can reach the capital, Pigadia, by car in about 12 mins: it is a lovely little authentic town,
we went there serveral times for fantastic dinner in the local taverns, very recommendable 'Ellinikon' meze taverna.
Just park your car at the central parking lot at the main taxi station.