My husband and I were on our honeymoon and we loved our stay at Maria's place. It has the most gorgeous view of the Caldera from two chairs that are just above the room itself. We sat out for most of the day trying to soak in the view, reading, and having drinks before dinner. It was the best price we could find in Oia for a room with such a beautiful view.
The room is also near shops and restaurants but it is a little removed from all the tourists that visit Oia. On your way down to the airbnb, there is a beautiful church that many tourists take pictures near (I snapped one or two myself-it is a very beautiful area!) but this tapers off before you get to the room itself. We felt lucky to stay in such a scenic area!