This is a really excellent studio apartment right in the middle of town, 10mins walk from port, 5 mins to the beach bar and swimming spot 'Vaporia' and 1 min walk to the Apollo Theatre and main square. There is a small balcony which is perfect for breakfast. You may get woken by the church bells (esp on weekends) but it's a nice way to wake up. The washing machine was very useful.
We were in town for the Animosyos Animation festival and being so close to the main venue was a delight. We would highly recommend the following places to eat: Kouzina (stunning food and wine) and Ousya (great pizza) both in Kiparissou area (the walking area with all the restaurants). Ano Syros old town is really wonderful for walking and seeing authentic houses but be warned it will test your fitness as very steep.. the whole town is basically narrow, atmospheric alleyways and steps.. great views. We found the only Taverna in Ano Syros open in late Sept, can't recall the name but it was just down the from the Markos Vamvakaris Museum (worth the 1 euro entry). There are cats everywhere and they are beautiful - very friendly.
A note re: the Island Buses. The timetables seem to change all the time so best thing is to walk to the main bus stop by the gas station, passed the ferry port and ask the drivers. There are a few routes around the Island's beaches - we loved Finikas (excellent food there too) but Kini is also lovely. if you get stuck a taxi back would be 12-20 euro dep on location.