This is a great option if you want to have a space and luxury as if you would stay in a resort in Thira or Oia (the most commercial and crowded parts of the island), but on a quiet and relaxed environment.
Make sure you rent a car on your arrival to Santorini so you can move freely.
The best aspect of our stay was our hosts; they are kind and respectful, and we received very useful recommendations to make plans for our whole stay.