Everything about Margarita and her property exceeded our expectations.
First the property: It is a beautiful, very recently renovated property. The pictures do not do it justice. We had a private balcony with our own jacuzzi. The common pool is a gorgeous infinity pool that is shared between the other 4 units looking over the vineyards below to the sea. The rooms are all well appointed and kept very very clean. The kitchen has what you need for light cooking. Perfect rental for 2 couples. Could also sleep 2 more in the livingroom (in singles) if needed.
The apartment is approximately 10 min walk to the town of Pyrgos. Very charming town with some shops, really fantastic restaurants (better food and much better value for money than in Oia and Thera) and a beautiful church. You will need to have a car or scooters to do much of anything else on the island - but that would be the case no matter where you stay. There is so much to do on Santorini and there is not really any public transit system to speak of. The central location is perfect for visiting Kamari and Perissa beaches on the east coast, Akrotiri and the Red Beach in the south and even with bad traffic you are only 30 minutes to Oia in the north. 15 mins to both the port and the airport. Unless you are going to rent in Kamari or Perissa and only spend all your days on the beaches there (which I wouldn't recommend) you will need a car.
As for Margarita, she is not only one of the nicest people I have met on AirBnB, but one of the nicest people I have ever met. She was always quick to reply to my questions when setting up the reservation. She was very accommodating - booked us a transfer from the airport, offered to set up car and boat rentals. We were traveling with a newlywed couple finishing their honeymoon on Santorini and she even offered to source roses for their room.
We would definitely stay here again.