This is a truly spectacular place to stay on Santorini. Just a quick walk outside the quiet village of Imerovigli and right on the main road. There is a bus stop just outside the house so you do not have to rent a car. The main hiking path that connects Fira to Oia runs right in front of the house and I highly recommend the hike - gorgeous views and not too terribly strenuous (My 60 year old parents did it with us).
While there is a decent amount of road noise it is not too noisy most of the time. It was really wonderful getting to sit outside and have such a beautiful views across the caldera to Oia. I highly recommend this house for a convenient, quiet stay while on Santorini.