My wife and I stayed here for 10 days in June, the place is located in a quiet residential section of the city, and from the port there are 111 steps (depending on the road you take) going up the hill. This can be a challenge with suit cases but we managed. Going up and down was not too much trouble, 5 minutes to go down to the main street and 10 minutes to climb up those stairs. Even in the middle of the night, the stairs are very well lit and we never had any issues.
The apartment is an authentic feel to living in Greece, and it has all the appliances needed so cooking and doing laundry was very easy.
Public transport was easy, especially on the weekends when they had frequent runs to the various beaches. The locals were all very helpful and courteous, and the island is not as expensive as the neighbouring touristy islands like Mikonos and Paros.
The host was very helpful and quick to respond to all of our questions.