We had a fantastic stay at Kosta's house. You will definitely need a car as it is set away from the main Karteros village area - we had a tough time finding the house at first as we missed the small right turning however Kostas came out and found us (thanks Kostas!).
It is only a 10 minute drive from the airport - some may be put off by this but we loved watching the planes arrive and depart.
The villa is a great location for getting around Crete as it is a 2 minute drive from the national road - we particularly loved Heraklion and Elounda.
The villa was spotless on arrival, very spacy over three floors, with 3 double bedrooms and a large open living and dining area.
The pool is amazing, very big and immaculately clean. The sunsets from the upstairs balcony are simply breath-taking. There was no refrigerant type air conditioning however this wasn't really an issue as there are good quality fans in each room.
All in all i would not hesitate to recommend Kosta's villa if you are looking for something quiet but is also a fantastic base to explore the island.