This is a super cool apartment in a neighborhood which, at first blush, seems like it might be mostly a tourist area. Don't be fooled; there are lots of locals, and lots of spots for locals, and many of the "tourist" places (restaurants, e.g.) are way nicer than they "need" to be to get business. (O Thanasis for souvlaki, Zuccherino for pastries and ice cream, Dia Tafta or Cherchez La Femme for Greek traditional food, T.A.F. for drinks, etc etc). The location is truly central, making it very easy to get to all the major sites/sights.
The apartment itself is a very nice place to stay, and Grigoris was a thoughtful host.