Location, location - we did NOT want to be in the center of the tourists, so this neighborhood (Kolonaki) was perfect for us. You can tell it’s a more affluent area, and safe. Great restaurants and shopping very close by.
It was about 25 minute walk to the Acropolis for us. We visited all the “busy” areas without staying in the middle of it.
The neighborhood is on a hill, so you should be prepared to walk up hill / up stairs. Not very difficult, just something to be aware of if you will stay here.
Apartment was clean and well kept. Hosts were responsive and left detailed instructions for check-in.