Spyros and Anthi's place is very well located. You can easily walk across to the Acropolis. My tip is to get to there early, before the heat and the crowds. The other great thing to do is to walk up to Pyxis, the hill between the apartment and the Acropolis with a couple of cold beers and a picnic from the supermarket near the train station and watch the sunset on the white marble of the big A. There's also a great bakery just up Alkifronus towards the railway line. Nice to pop up there and grab some fresh baked goods for breakfast and have a chat to the Baker. There's a great square just around the corner too, to hang out of an evening and soak up the Rowdy crowd that is Athenians at leisure.