I had a great stay at Michalis and Kleio's place. It's in a neighborhood close enough to all the major sights, but away from all the tourist crowds. As long as you're okay with walking some walking up and down hills, it's an excellent choice for a solo traveler or couple.
The area is 100% local, with plenty of cafes, restaurants, grocery shops, and even a donut shop if you look carefully. Apartment is conveniently on the ground floor, but facing the inner area so it's not too noisy. It's clean and modern, with all the touches you expect of a contemporary urban dwelling. Kleio was always helpful and quick with her responses, and gave some great tips for places to visit.
I would definitely stay here again without reservations, and look forward to the opportunity in the near future!