Great accommodation! I stayed there for nine days and really enjoyed it! Room is isolated from the rest of the apartment and has private bathroom. It's totally silent, I was working almost every day and that was important for me.
Location is perfect, if you want to explore downtown you don't need public transport at all, but if you need metro for further locations, metro station Narodni Trida is close. If you are hungry, you can find food 24/7 in Spalena street, but if you want real meals during the day, I could recommend "U Pravdu" restaurant in Zitna street.
Also, if you want to walk by the river or to jump, Vltava and bridges are close, 300 m from apartment and view is beautiful.