We enjoyed of staying at Monika's apartment - everything was perfect :)
Firstly, building is new and modern. Apartment is fancy, new, very clean, bright, beautifully decorated, fully equipped (you can cook, enjoy Nespresso, there is dishwashing machine, washer with drying option, TV with lots of channels, good WiFi, and many other things). Also, there is no personal stuff of host / owner.
House is located in Smichov (Andel) 5 mins walking to public transport stations (metro, trams...). Basically you can get where you want from this place (even by foot). We like this area - it is modern and dynamic; there are a lot of restaurants, supermarkets (tesco and others), shopping centers (Novy Smichov for example), for every taste.
I was working all the week, while my wife was staying with our 3 years old boy - she also has very positive feedback as it was fully OK for her to stay in the apartment, go outside, etc. For children apartment is also safe.