Very nice appartment. We were a group of seven men, coming to Prague for a three-day-visit to experience a brewery tour and enjoying the night life. We didn't miss anything in the appartment, it was very calm and had a lot of space for sleeping.
You need ca. 15 min by foot to the national museum, where you can visit some clubs, museums, restaurants etc. (you can also go by metro for one stop) and for example ca. 25 min by foot to the karls bridge.
We definately would stay in this appartment again next time. ;-)
One note for big groups: There's just one toilet, which is seperated from the bathroom.