I recommend Aneta & Petr's place in the heart of Prague. I'm going to stay with them next time I visit this beautiful city. Petr and Anet do their best to accommodate your every wish.
The communication is perfect, professional and in time manner. The place is super clean, very comfortable with a big TV (incl. Netflix) and a kitchen with all facilities you might need (including a washing machine). On top of that, you'll get many tips what to do and see in Prague. Thank you.