Prague is a such a lovely place and visiting is must do. Having hosts like Renata and her family will definitely add much to your experience there. The house is situated about 20-25 minutes from the city centre by bus and metro. There are several good restaurants in this area Battista brickyard and Restaurace Červený Mlýn.
All members of her family speak great English and are very responsive and willing to give you great suggestions on what to see and do in Prague.
All in all, highly recommend staying with them when visiting Prague.