We travel to CZ at least twice a year and prefer staying in this area. The Metro B line is right around the corner and you’re downtown in less than 30 minutes. Metro B also stops at Anděl which is a hoping area with shops, restaurants, Staropramen Brewery and a major bus stop where busses go to other regions of CZ and neighboring countries.
Around the apartment called the ‘British Section’ there are small specialty shops, hairdressers and restaurants. A short 8 minute walk will get you to a bigger shopping area where there’s an IKEA and Tesco. We also went there to get our mandatory Covid test to return to the USA.
If you have a car I highly recommend paying extra for a parking spot in the building’s garage. Parking on the street is a nightmare because people who work in nearby office buildings use the street parking. Plus, many Czechs drive to this Metro stop, park their cars for free and use the metro to get downtown.
A personal tip download the Mapy.cz app. This app is far more detailed than Apple Maps, Google maps and WAZE. It can be used in several languages.