The loft is very large, clean, and comfortable - we stayed with four adults and two kids and there was more than enough space. The views are fantastic from the balcony.
The crib/cot provided for our ten month old was very nice and saved us the trouble of bringing one. A high chair was provided as well.
The location is great for sightseeing, close to the metro and an easy walk from tram 22, which is very convenient to many sights. Romana arranged an excellent walking tour for us the first morning after we arrived which was wonderful- we were able to get a feel for the city right away.
We had a bit of trouble with the airport pickup but called Romana and she got it sorted out for us quickly. We definitely recommend this loft for your stay in Prague!