The apartment is in a good location with a lot of shops, restaurants, and cafes around. I recommend cafefin which I particularly enjoyed for breakfast. There is a supermarket ( Albert ) close by too.
This airbnb is not too far from the historical centre. You can take the metro which is very close to the stay. It's cheap and fast ( around 3 stops ) and easy to use. There are also many tram connections. You can walk into old town ( if you enjoy walking ) and that will take about half an hour.
The room looked cool and I appreciated the desk and small sofa which I found very handy for working on the laptop. There is a good amount of space for storing clothing and personal items. The door locks which is good for security. The Internet connection was very good!
However, it is not perfect. I would say the bathroom could be a little bit cleaner. For me, it's not a problem, I don't care at all, but just mentioning it if you are a super clean freak. Personally, I was okay with it. I am not sure what is going on with the heating. Sometimes it turns on and sometimes not?
The biggest negative I would say is that I found the bed very uncomfortable. It's not a proper bed. It's a thin ( un-sprung ) mattress laying on top of hard wood. While staying here I didn't get a good night's sleep once because it is very uncomfortable. This did impact the quality of my time in Prague as I was constantly tired. Because of the bed I would only really recommend this as a short term stay.