I highly recommend Filip's apartment. It has everything you may need, a lift to bring up the luggage, a lot of space, fully equipped kitchen, 2 bathrooms and 2 toilets, a lot of towels, washing machine, small things like tea, coffee and sugar. There were 4 of us, and we all felt very welcome, home away from home.
The location is perfect - short walk to the centre of Prague, but away from the chaos of the tourist centre. Quiet and spacious, with comfortable bedding, we had a great sleep every night.
Local restaurants and pubs are amazing, authentic and not as expensive as in the tourist route.
Overall - great, highly recommended family friendly place and thoughtful host.