Ondřej's apartment was lovely and Ondřej was a perfect host. The apartment is well located adjacent to Wenceslas Square, and within walking distance to Old Towne, Charles Bridge, and the Jewish Quarter, although we bought passes and used the trams. There is a terrific restaurant 'Styl & Interier' right in the building and several more in the neighborhood.
We recommend Ondřej’s location as a terrific space but would recomend assigning the more nimble of your party to the loft space.