Our stay at the appartment of Nick and Jenny was very nice. The appartment was within walking distance to the central train station and had everything we needed. It is located in a quiet neighborhood with some good restaurants close by and a small supermarket directly in the street. If you want to relax after a long day of sightseening you can go to the nearby park.
Our communication with our hosts was always pleasant and they answered to our questions very fast. If you stay in Prague, I definetly recommend you to select one of the flats of Nick and Jenny.