I had a great stay at Jakub's Hotel! The location is great: a 5-10 minute walk away from a metro station, and about one minute away from a tram stop (very efficient in Prague).
The bed is very comfortable, and the blackout blinds will help you sleep super comfortably. Great service overall, I got my room cleaned and new towels every other day, the bathroom and shower are very comfortable, and Jakub gave me a larger desk to work from my room.
Highly recommended if you're staying in Prague for a week or so, don't hesitate to book!