Simply put: I wish my own house was like this! It is a 'refuge' in the middle of the busy old town. A spacious apartment with 2 bedrooms and 2 bathrooms, very cosy on the attic of an old apartment building, located in the old town. Karluv Most (Charles Bridge) is at just 5 minutes walking, as is the old town square. After strolling the town for a few hours, you only need to climb the stairs (no elevator alas) to the apartment and enjoy the peace and quiet.
The only backdraws I encountered was the difficulty of parking the car (I recommend the Rudolfinum parking garage at 10 minutes walking distance, not cheap though at 600 kr/day), and the crockery (dishes, cutlery, cups) not very clean. But it's a perfect base to discover Prague!