Fantastic location, fantastic apartment, and fantastic people! Monika and Jaroslav are wonderful hosts; I had a great time sharing drinks with them at a lovely bar near the apartment.
The apartment itself is basically perfect -- it's in a perfect location as it is literally steps from the Old Town square (and in Prague's beautiful and historic Jewish district) but still quiet enough to be restive even on weekend nights. You also get a view of Kafka's birthplace from your bedroom window which is exciting for the nerdy part of me. Most of tourist attraction are an easy (and picturesque) walk from the city, and Monika and Jaroslav helped me with directions to find the few things I couldn't find.
Also, based on how great the bar they took me out was and the delicious Bakeshop recommendation, I would trust their recommendations on food and going out places too.

Great experience overall!