This studio apartment is located on a excellent location if you want to be close to the city centre but still want to be in a fairly quiet place. You can be in the centre of the city in around 10 minutes by foot. Keep in mind that the apartment is on a hill. If you don't want to walk a lot I believe there is a tram nearby.
The communication is top notch. Every time we had a question it would be answered really fast. One of the better hosts I've had with airbnb. Even if Daniela isn't near it's still easy to check-in and out via a lockbox with a code.
The apartment is small, but certainly big enough for two people. It's clean with everything you need for a few days in Prague.
The taxi from the airport to the apartment is relatively cheap so I would advice taking one. Daniela even offered us to order one for us which we did on the way back.