Vadim's apartment is super central - we walked everywhere, even to the (main) train station. nevertheless it is calm during the night, due to the apartment being in a courtyard rather than being right at the street.
The apartment has everything that is needed for a short stay, just I wouldnt try overly complicated cooking sessions-which is not a problem, because due to that you can try some of the many restaurants in Prague :)
i would come again