Really well located, but consider that this is the town centre and many young people come here to drink. We had some 6 Brits hollering in the apartment above us till 1AM, ignoring our requests for quiet. Fortunately we speak Czech, so we called 156 to alert the police and three burly officers brought the guys to order withing a few minutes. I think they will respond to a call in English as well, but not sure.
The company office, however, was unresponsive for two days and only responded to our multiple attempts to contact them (through their system, Airbnb, email, and phone) after we had escalated to Airbnb just 3 hours before our arrival to Prague.
Other than that, the apartment was really nice and I would get it again if the company can improve the customer service at the officed. The surprising thing was that the young man who handed over the key (you need to pick it up at the office - different location in Praha 1), did not think he should apologise for the inconvenience they caused us by not responding.