My wife and I recently spent 4 nights in Prague and stayed at Anna's place on Sokolovska. The apartment is perfect. Spotless. Plenty large enough and inviting.
We met Anna and her husband right away (they live upstairs). They were pleasant and helpful.
The location is, in my mind, perfect. It is not downtown, so the crowds of tourists are absent. Getting downtown is about a 20 minute walk. A tram, which stops two doors down, will take you to Wenceslaus Square in about 5 minutes.
And right across the street, there is a quiet park with a playground and huge old church.
We would stay there again in a minute.