Definitely the place to go if you're looking for a small room in a calm neighborhood. Sarah is a wonderful host ready to help you with anything.
The subway is a 10 minute bus ride from her house (bus stop right by her house) or alternately you can walk 10 minutes to the street car (tramway). Both can bring you downtown within 40-50 minutes.
There is also a brand new shopping mall right by her house (5 minute walk).