I stayed here for 3 nights for an interview and the location was perfect. It was no more than a 20-minute walk to the heart of the city (with faster options of the streetcar which was very close). The neighbourhood is very quiet, right next to a park.
Jon made my first AirBnB experience very pleasant, and not once did I feel uncomfortable or wary. He went out of his way to offer an umbrella (for about the one rainy day they've had all summer in Toronto! ;) and he even accommodated me when I needed to leave my suitcase for a few hours after checkout (at my own risk of course).
Overall I would definitely recommend Jon and his perfect location downtown.