Right in the middle of Leslieville, close to some amazing restaurants, and only 16-60 min walk to downtown Toronto (depending on where you are trying to go). I stayed at Heather's place to attend a course for work, while also having a bit of a holiday, and it was absolutely perfect for me. It was homely, had everything I needed in terms of a kitchen and bathroom. The only thing it is missing is a washing machine, but there are many public laundromats only 5 mins walk away so I didn't find it to be a huge inconvenience at all. There's an aerial/circus studio and many gyms only 10 mins walk away, and the house is located on a quiet street so it is ideal if you are a light sleeper or prefer your own privacy.
Heather is such a lovely host, very friendly and welcoming and super prompt with all her responses. I would highly recommend her place to stay if you are looking for somewhere quieter that is still a walking distance away from the main city.