This is the perfect place to stay at if you want to cover a lot of places in Vancouver. There isn't much around the airbnb, but the drive to all of the places we wanted to go to (Gastown, Granville, Richmond Night Market, etc) were all within a 20 minute drive. Taxi-wise, the most we spent was around $30 which was to the airport.
They also have a washer and drier that comes handy. This is very useful if you don't want to take dirty clothes home, or if you want to wear or re-wear can toss it into the wash. Didn't realize how much of a benefit it is until I used it
If you go during the fall, the neighbourhood is perfect for pictorials. The trees are just full of vibrant fall colour!