Blake's apartment was a perfect fit for us - a couple staying four days in Vancouver. Check in was seamless and the apartment clean and well appointed. The view over the city is quite nice too.
We were looking for something central and Yaltown was a good balance. The apartment is a short two minute walk from the train station which will take you pretty much anywhere you want to go (including the airport, Gastown, or Downtown.
We spent most of our time out of the apartment in Gastown and down main street, nothing is really too far away in Vancouver. My only tip would be to bring ear plugs. Like any city, at night can be noisy even on the 23rd floor when you have the windows open.