If you're thinking of booking this space: do it! You won't regret it. I stayed at Derrick's loft for an entire month and I couldn't have chosen a better place to stay while in Vancouver.
The loft itself is exactly as pictured and more. It is bright and spacious, beautifully designed, and comes equipped with everything you could need for a long term stay. The hosts are also extremely responsive and available; from check in to any minor questions, they were quick and replied with care.
The location is as the other reviews describe. It is minutes away from the heart of Gastown, filled with incredible bars, restaurants, cafes, and shopping. If you're unfamiliar with the area, there can be rough spots, but I had no issues at all during my stay and generally Gastown is very lively and touristy and I'd say it's quite safe.
I'd absolutely stay here again and I can't recommend this accommodation enough.