Nothing beats living in an authentic house right in the heart of Ghent. Lots of cafes nearby, everything's at a walking distance. Trui put quite some effort into her guide here on Airbnb (also has plenty of tourist info for you and will answer any questions you might have), so make sure to check it out. Trui's a great host, truly treats guests like, well, guests, and a pleasure to chat with (mostly listen to, though, since I'm not much of a talker). Can't recommend this place enough. :)