Number22 is a great basecamp to scout out Antwerp city. It is not large but nicely decorated and situated in a beautiful old building with lots of character. The location is very central, in the heart of the south part of the centre, which is a very nice area with lots of theatres, cafe's restaurants, alternative boutiques, and small shops. If you want to stay away form the mainstream and more touristic shopping streets than this is a great place to start. Frederic is a nice guy, relaxed and helpful so no complaints there :)