Only stayed for one night but the place seemed solid, certainly in a good location for anyone utilizing public transport and taking the SkyBus to/from the airport. So, if you have heavy luggage this will save you quite a bit of hauling things around. Some nice breakfast spots around the area and within walking distance of a ton of Melbourne's attractions.
Only real issue is with the building, the elevators are crazy slow and seem to constantly be packed. The elevator on the way down seems to stop every four or five floors which will really slow you down coming from 43rd floor. Make sure you allow some extra time for this if you have a dinner reservation or something.