We really lucked out in booking a spot in Cameron's place in Palmero Soho in Buenos Aires. The place is fantastic, with two bedrooms, 1.5 baths and a full kitchen that was easy to use. Safety wasn't a concern; the security staff was nice and it's a few floors up. You're a few blocks from the Plaza Italia and if you're inclined to take on the taxi mafia in BA, you shouldn't have a problem getting a taxi.
The best part of this apartment is picking a street and seeing what restaurants and bars popped up. This neighborhood is the place to be for most residents. Also, ask Cameron for a list of where to go and what to do and you will be set for your duration in the city. Cameron is a great host, he is prompt, attentive and knows what he's doing and knows the city. You're really enjoy this place in Buenos Aires.