I stayed with Dora for a month. She was an extremely gracious hostess who helped with everything from how to get around Buenos Aires to patiently dealing with my attempts at Spanish.
The apartment is beautifully decorated with art (Dora's among others) and painted in lovely colours. Everything is nice and clean and the building is safe (24-hour security who are very friendly) and modern.
Almagro is very central and if you enjoy walking (which is helpful in Buenos Aires) you can get to most places of interest in under an hour, faster by public transport (but ask Dora, Google Maps is usually wrong). For those on a budget there is a (albeit very slow) bus from the International airport that stops in front of the house.
The area is very Porteno, the experience very local. I hardly ever noticed other tourists. You do want to use common sense, but (as in most of Buenos Aires) I felt safe here.
Solely the internet was a bit temperamental at times (better in mornings).