Right in the heart of Palermo and we were able to walk everywhere we needed to get to during the trip. There are numerous restaurants, cafe and empanada shops that you won’t need anything else in that regard. Palermo is also close enough to San Telmo and Recoleta that if you’re willing, walking is worth it to see all the different buildings and sites along the way. The room had everything you’d need for a stay.
Had no problem getting Ubers very quick which helped for some further away areas.
With that said, you’re in the city and their is plenty of noise. Bring earplugs and it’s not a problem, they also have some in the room. It’s a busy city and things start early (buses/trucks) and run late (people). Set expectations accordingly and it’s a non issue.
Would happily stay again.