My friends and I stayed 3 nights and the location of this house was perfect! You may walk to Centro; it doesn't take long. We used to walk for everywhere. As you know, Centro means hub for everywhere.
Plus, the owner of this house, Fernando, didn't make any complain though he had to wait for us for four hours!!!
Though the house was narrow than our expectation and many locks were hassle for us to open and close, Fernando was kind enough and seemed he likes things neat and tidy. Plus, he wanted to help us a lot and there was a chance! When we needed later check-out, he loved to help us! On behalf of us, he delayed our check out for almost a day!!! We didn't need to use coin locker at the bus terminal.
If, furthermore, you want to watch the tango show near your stay, this house can be the answer because there is a famous tango & dinner place in the same building. So, we, three women, could enjoy the show and back to house safely though the show ended almost midnight! Hope to enjoy your time in Buenos Aires as much as we did!