Table:
Study	QA score	Quality rating	Adherence definition	Adherence is primary outcome?	Data on predictors of adherence?	Data on adherence and outcomes?	N	MTX adherence rate	95% CI/SD
MEMS
de Klerk et al22	12	Low	Per cent of adherence (ratio)	Yes	Yes	No	23	107%	98 to 117
Waimann et al30	15	High	Per cent of adherence (ratio)	Yes	Yes	Yes	76	63%	20%
Pharmacy refill
Harley et al21	8	High	Per cent of adherent (MPR ≥80%)	Yes	No	No	1668	64%	24 to 102
Grijalva et al23	15	High	Per cent of adherence (MPR)	Yes	Yes	No	2933	80%	NP
Grijalva et al25	9	High	Per cent of adherence (MPR)	No	No	No	NP	59%	31 to 82
de Thurah et al26	14	High	Per cent of non-adherence (CMG)	Yes	Yes	No	941	12%	1113
Cannon et al28	15	High	Per cent of adherent (MPR ≥80%)	Yes	No	Yes	384	84%	NP
Self-report
Contreras-Yanez et al24	11	Low	Per cent of adherent (7-day DRR ≥80%)	Yes	Yes	Yes	10	78%	NP
de Thurah et al27	14	High	Per cent of non-adherent (CQ-R ≤25th centile)	Yes	Yes	No	8565	BL 23%9 mo 23%	NPNP
Salt and Frazier29	9	Low	Per cent of adherent (MARS ≥39)	Yes	Yes	No	77	92%	NP

Convert the image to Markdown syntax.

| Study | QA score | Quality rating | Adherence definition | Adherence is primary outcome? | Data on predictors of adherence? | Data on adherence and outcomes? | N | MTX adherence rate | 95% CI/SD | 
 | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | 
 | <COLSPAN=10> MEMS | 
 | de Klerk et al22 | 12 | Low | Per cent of adherence (ratio) | Yes | Yes | No | 23 | 107% | 98 to 117 | 
 | Waimann et al30 | 15 | High | Per cent of adherence (ratio) | Yes | Yes | Yes | 76 | 63% | 20% | 
 | <COLSPAN=10> Pharmacy refill | 
 | Harley et al21 | 8 | High | Per cent of adherent (MPR ≥80%) | Yes | No | No | 1668 | 64% | 24 to 102 | 
 | Grijalva et al23 | 15 | High | Per cent of adherence (MPR) | Yes | Yes | No | 2933 | 80% | NP | 
 | Grijalva et al25 | 9 | High | Per cent of adherence (MPR) | No | No | No | NP | 59% | 31 to 82 | 
 | de Thurah et al26 | 14 | High | Per cent of non-adherence (CMG) | Yes | Yes | No | 941 | 12% | 1113 | 
 | Cannon et al28 | 15 | High | Per cent of adherent (MPR ≥80%) | Yes | No | Yes | 384 | 84% | NP | 
 | <COLSPAN=10> Self-report | 
 | Contreras-Yanez et al24 | 11 | Low | Per cent of adherent (7-day DRR ≥80%) | Yes | Yes | Yes | 10 | 78% | NP | 
 | de Thurah et al27 | 14 | High | Per cent of non-adherent (CQ-R ≤25th centile) | Yes | Yes | No | 8565 | BL 23%9 mo 23% | NPNP | 
 | Salt and Frazier29 | 9 | Low | Per cent of adherent (MARS ≥39) | Yes | Yes | No | 77 | 92% | NP |