Table:
Change in clearance hemofiltration vs hemodialysisa
Molecular substance	Number of trials; number of patients randomized	Effect estimate	95% confidence interval	P-value	Heterogeneity (I2)
Smaller molecules
Urea (60 Da)	4 [33,36-38]; 49	+1%b	-2% to +3%	0.60	0%
Phosphate (95 Da)	1 [37]; 18	0%c	-4% to +4%	1.00	n/a
Creatinine (113 Da)	3 [33,37,38]; 43	+1.8%b	-0.4% to +4.1%	0.12	0%
Uric acid (168 Da)	2 [33,37]; 28	+4%	+1% to +7%	0.01	0%
Larger molecules
Vancomycin (1.8 kDa)	1 [33]; 10	+18%	+8% to +28%	0.0003	n/a
β2-microglobulin (11.8 kDa)	2 [37,38]; 33	+94%d	+78% to +112%	<0.0001	0%
IL-1 Receptor Agonist (16-18 kDa)	1 [24]; 12	+77%e,f	+24% to +153%	0.002	n/a
Retinol Binding Protein (21.2 kDa)	1 [37]; 18	+42%	+4% to +94%	0.03	n/a
IL-6 (26 kDa)	2 [24,34]; 22	+6%f,g	-62% to +191%	0.91	89%

Convert the figure to Markdown syntax.

|  |  | <COLSPAN=4> Change in clearance hemofiltration vs hemodialysisa | 
 | Molecular substance | Number of trials; number of patients randomized | Effect estimate | 95% confidence interval | P-value | Heterogeneity (I2) | 
 | --- | --- | --- | --- | --- | --- | 
 | <COLSPAN=6> Smaller molecules | 
 | Urea (60 Da) | 4 [33,36-38]; 49 | +1%b | -2% to +3% | 0.60 | 0% | 
 | Phosphate (95 Da) | 1 [37]; 18 | 0%c | -4% to +4% | 1.00 | n/a | 
 | Creatinine (113 Da) | 3 [33,37,38]; 43 | +1.8%b | -0.4% to +4.1% | 0.12 | 0% | 
 | Uric acid (168 Da) | 2 [33,37]; 28 | +4% | +1% to +7% | 0.01 | 0% | 
 | <COLSPAN=6> Larger molecules | 
 | Vancomycin (1.8 kDa) | 1 [33]; 10 | +18% | +8% to +28% | 0.0003 | n/a | 
 | β2-microglobulin (11.8 kDa) | 2 [37,38]; 33 | +94%d | +78% to +112% | <0.0001 | 0% | 
 | IL-1 Receptor Agonist (16-18 kDa) | 1 [24]; 12 | +77%e,f | +24% to +153% | 0.002 | n/a | 
 | Retinol Binding Protein (21.2 kDa) | 1 [37]; 18 | +42% | +4% to +94% | 0.03 | n/a | 
 | IL-6 (26 kDa) | 2 [24,34]; 22 | +6%f,g | -62% to +191% | 0.91 | 89% |