Table:
Item	Baseline	Week 2	Week 4	Week 8	P (2,0)	P (4,0)	P (8.0)
Pain severity
With tenderness	7.60 ± 1.14	3.60 ± 1.14	5.00 ± 0.71	5.60 ± 1.14	< 0.001	< 0.001	< 0.001
Without tenderness	7.21 ± 1.03	3.47 ± 1.43	4.63 ± 1.38	5.21 ± 1.03	< 0.001	< 0.001	< 0.001
p-value	0.515	0.840	0.425	0.515	< 0.001	< 0.001	< 0.001
Pain frequency	< 0.001	< 0.001	< 0.001
With tenderness	14.40 ± 1.34	7.40 ± 2.41	9.00 ± 2.12	1.00 ± 1.58	< 0.001	< 0.001	< 0.001
Without tenderness	11.58 ± 3.73	6.26 ± 1.63	7.21 ± 1.96	9.47 ± 3.70	< 0.001	< 0.001	< 0.001
p-value	0.067	0.364	0.140	0.242	< 0.001	< 0.001	< 0.001
Drug use	< 0.001	< 0.001	< 0.001
With tenderness	14.60 ± 1.34	7.00 ± 1.22	9.00 ± 1.22	12.60 ± 1.34	< 0.001	< 0.001	< 0.001
Without tenderness	12.21 ± 3.10	6.05 ± 1.93	7.47 ± 2.34	10.21 ± 3.10	< 0.001	< 0.001	< 0.001
p-value	0.111	0.208	0.069	0.111	< 0.001	< 0.001	< 0.001

Express the image as Markdown code.

| Item | Baseline | Week 2 | Week 4 | Week 8 | P (2,0) | P (4,0) | P (8.0) | 
 | --- | --- | --- | --- | --- | --- | --- | --- | 
 | Pain severity |  |  |  |  |  |  |  | 
 | With tenderness | 7.60 ± 1.14 | 3.60 ± 1.14 | 5.00 ± 0.71 | 5.60 ± 1.14 | < 0.001 | < 0.001 | < 0.001 | 
 | Without tenderness | 7.21 ± 1.03 | 3.47 ± 1.43 | 4.63 ± 1.38 | 5.21 ± 1.03 | < 0.001 | < 0.001 | < 0.001 | 
 | p-value | 0.515 | 0.840 | 0.425 | 0.515 | < 0.001 | < 0.001 | < 0.001 | 
 | Pain frequency |  |  |  |  | < 0.001 | < 0.001 | < 0.001 | 
 | With tenderness | 14.40 ± 1.34 | 7.40 ± 2.41 | 9.00 ± 2.12 | 1.00 ± 1.58 | < 0.001 | < 0.001 | < 0.001 | 
 | Without tenderness | 11.58 ± 3.73 | 6.26 ± 1.63 | 7.21 ± 1.96 | 9.47 ± 3.70 | < 0.001 | < 0.001 | < 0.001 | 
 | p-value | 0.067 | 0.364 | 0.140 | 0.242 | < 0.001 | < 0.001 | < 0.001 | 
 | Drug use |  |  |  |  | < 0.001 | < 0.001 | < 0.001 | 
 | With tenderness | 14.60 ± 1.34 | 7.00 ± 1.22 | 9.00 ± 1.22 | 12.60 ± 1.34 | < 0.001 | < 0.001 | < 0.001 | 
 | Without tenderness | 12.21 ± 3.10 | 6.05 ± 1.93 | 7.47 ± 2.34 | 10.21 ± 3.10 | < 0.001 | < 0.001 | < 0.001 | 
 | p-value | 0.111 | 0.208 | 0.069 | 0.111 | < 0.001 | < 0.001 | < 0.001 |