Table:
Clinical trial	Patient population	Restrictive strategy (Hb trigger – target) (g/dl)	Liberal strategy (Hb trigger – target) (g/dl)	Reduction in blood utilization	Primary outcome
Event	Restrictive strategy incidence (%)	Liberal strategy incidence (%)	Pvalue
Hébert and colleagues [3] (n = 838)	Critically ill (adults)	7 to 8.5	10 to 10.7	54% less RBC units transfused	30-day mortality	18.7	23.3%	0.11
Hajjar and colleagues [5] (n = 502)	Cardiac surgery (adults)	8 to 9.1	10 to 10.5	58% less RBC units transfused	Composite endpoint	11	105	0.85
• 30-day mortality	6	6	0.93
• Cardiogenic shock	9	1	0.42
• ARDS	2	5	0.99
• Acute renal injury requiring dialysis	4	0.99
Carson and colleagues [7] (n = 2,016)	Femur fracture (older adults)	8.0 to 9.5	10.0 to 11.0	65% less RBC units transfused	Composite endpoint	34.7	35.2	NS
• 60-day mortality	28.1	27.6	NS
• 60-day inability to walk	6.6	7.6	NS
Villanueva and colleagues [9] (n = 921)	Gastrointestinal bleeding (adults)	7 to 9.2	9 to 10.1	59% less RBC units transfused	45-day all-cause mortality	5	9	0.02
Holst and colleagues (n = 998) [8]	Sepsis in the ICU (adults)	<7.0	7.0 to 9.0	50% less RBC units transfused	90-day all-cause mortality	43	45	0.44

Interpret the illustration as Markdown format.

| Clinical trial | Patient population | Restrictive strategy (Hb trigger – target) (g/dl) | Liberal strategy (Hb trigger – target) (g/dl) | Reduction in blood utilization | <COLSPAN=4> Primary outcome | 
 |  |  |  |  |  | Event | Restrictive strategy incidence (%) | Liberal strategy incidence (%) | Pvalue | 
 | --- | --- | --- | --- | --- | --- | --- | --- | --- | 
 | Hébert and colleagues [3] (n = 838) | Critically ill (adults) | 7 to 8.5 | 10 to 10.7 | 54% less RBC units transfused | 30-day mortality | 18.7 | 23.3% | 0.11 | 
 | Hajjar and colleagues [5] (n = 502) | Cardiac surgery (adults) | 8 to 9.1 | 10 to 10.5 | 58% less RBC units transfused | Composite endpoint | 11 | 105 | 0.85 | 
 |  |  |  |  |  | • 30-day mortality | 6 | 6 | 0.93 | 
 |  |  |  |  |  | • Cardiogenic shock | 9 | 1 | 0.42 | 
 |  |  |  |  |  | • ARDS | 2 | 5 | 0.99 | 
 |  |  |  |  |  | • Acute renal injury requiring dialysis | 4 |  | 0.99 | 
 | Carson and colleagues [7] (n = 2,016) | Femur fracture (older adults) | 8.0 to 9.5 | 10.0 to 11.0 | 65% less RBC units transfused | Composite endpoint | 34.7 | 35.2 | NS | 
 |  |  |  |  |  | • 60-day mortality | 28.1 | 27.6 | NS | 
 |  |  |  |  |  | • 60-day inability to walk | 6.6 | 7.6 | NS | 
 | Villanueva and colleagues [9] (n = 921) | Gastrointestinal bleeding (adults) | 7 to 9.2 | 9 to 10.1 | 59% less RBC units transfused | 45-day all-cause mortality | 5 | 9 | 0.02 | 
 | Holst and colleagues (n = 998) [8] | Sepsis in the ICU (adults) | <7.0 | 7.0 to 9.0 | 50% less RBC units transfused | 90-day all-cause mortality | 43 | 45 | 0.44 |