Table:
Interaction covariate	One‐stage	Two‐stage
Amalgamated interaction (95% CI), p‐value	Within‐trial interaction (95% CI), p‐value	Across‐trial interaction (95% CI), p‐value	Within‐trial interaction (95% CI), p‐value
Age	−0.067 (−0.094 to −0.040), <0.001	−0.050 (−0.116 to 0.017), 0.142	−0.071 (−0.100 to −0.041), <0.001	−0.049 (−0.115 to 0.017), 0.142

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| <ROWSPAN=2> Interaction covariate | <COLSPAN=3> One‐stage | Two‐stage | 
 | Amalgamated interaction (95% CI), p‐value | Within‐trial interaction (95% CI), p‐value | Across‐trial interaction (95% CI), p‐value | Within‐trial interaction (95% CI), p‐value | 
 | --- | --- | --- | --- | --- | 
 | Age | −0.067 (−0.094 to −0.040), <0.001 | −0.050 (−0.116 to 0.017), 0.142 | −0.071 (−0.100 to −0.041), <0.001 | −0.049 (−0.115 to 0.017), 0.142 |