Irritable bowel syndrome
Table:
Irritable bowel syndrome
Other names	Spastic colon, nervous colon, mucous colitis, spastic bowel[1]

Drawing of the pain of IBS
Specialty	Gastroenterology
Symptoms	Diarrhea, constipation, abdominal pain[1]
Usual onset	Before 45 years old[1]
Duration	Long term[2]
Causes	Unknown[2]
Diagnostic method	Based on symptoms, exclusion of other diseases[3]
Differential diagnosis	Celiac disease, non-celiac gluten sensitivity, microscopic colitis, inflammatory bowel disease, bile acid malabsorption, colon cancer[3][4]
Treatment	Symptomatic (dietary changes, medication, probiotics, counseling)[5]
Prognosis	Normal life expectancy[6]
Frequency	12.5% (developed world)[1][7]

Consulting the table, assess whether the statement is entailed, neutral, or refuted. Provide the verdict inside {"answer": "YOUR ANSWER"} as JSON.

Claim: IBS' frequency has increased over time.

answer: neutral