Breast cancer
Table:
Breast cancer

Mammograms showing a normal breast (left) and a breast with cancer (right, white arrows).
Specialty	Oncology
Symptoms	Lump in a breast, change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly inverted nipple, red scaly patch of skin[1]
Risk factors	Female, obesity, lack of exercise, alcohol, hormone replacement therapy during menopause, ionizing radiation, early age at first menstruation, having children late or not at all, older age, prior breast cancer, family history, Klinefelter syndrome[1][2][3]
Diagnostic method	Tissue biopsy[1]
Treatment	Surgery, radiation therapy, chemotherapy, hormonal therapy, targeted therapy[1]
Prognosis	Five-year survival rate ≈85% (US, UK)[4][5]
Frequency	2.1 million affected as of 2015[6]
Deaths	627,000 (2018)[7]

From the table, state whether the hypothesis is entailed, neutral, or refuted. Provide the verdict inside {"answer": "YOUR ANSWER"} as JSON.

Hypothesis: As of 2015, over 2 million people have been affected by breast cancer.

answer: entailed