Cushing's syndrome
Table:
Cushing's syndrome
Other names	Hypercortisolism, Itsenko-Cushing syndrome, hyperadrenocorticism

Person's facial appearance 3 months after treatment with inhaled fluticasone[1]
Specialty	Endocrinology
Symptoms	High blood pressure, abdominal obesity with thin arms and legs, reddish stretch marks, round red face, fat lump between the shoulders, weak muscles, acne, fragile skin[2]
Usual onset	20–50 years[3]
Causes	Prolonged exposure to cortisol[3]
Diagnostic method	Requires a number of steps[4]
Treatment	Based on underlying cause[5]
Prognosis	Generally good with treatment[6]
Frequency	2–3 per million people per year[7]

From the table, identify if the claim is entailed, neutral, or refuted. Give your final answer in JSON format {"answer": "YOUR ANSWER"}.

Sentence: Cushing's syndrome affects at least two million people a year.

answer: entailed