Harding lived in rural Ohio all his life, except when political service took him elsewhere. As a young man, he bought The Marion Star and built it into a successful newspaper. In 1899, he was elected to the Ohio State Senate; he spent four years there, then was elected lieutenant governor. He was defeated for governor in 1910, but was elected to the U.S. Senate in 1914. Harding died of a heart attack in San Francisco while on a western tour and was succeeded by Vice President Calvin Coolidge.