color, and any Shar-Pei with a 'flower-coat' (white with either black or blue patches) is a disqualification. Dogs with allergic skin disease often get allergy-induced skin infections. Shar-Pei are also at an increased risk of demodicosis, a disease which happens when Demodex canis mites proliferate and cause skin irritation, inflammation and infection.Familial Shar-Pei fever (FSF) is a serious congenital disease that causes short fevers lasting from 24 hours to sometimes up to three days and usually accompanied by accumulation of fluid around the ankles (called Swollen Hock Syndrome). Amyloidosis, a long-term condition, is most likely related to FSF, caused by unprocessed amyloid proteins depositing in the organs, most often in the kidneys or liver, leading eventually to kidney failure. The disease is associated with the western type and it is estimated that 23% are affected. The Australian breed standard was changed in 2009 to discourage breeding for heavy wrinkling.A common problem is a painful eye condition, entropion, in which the eyelashes curl inward, irritating the eye.