During the early 1790s, Madison came to oppose the economic program and accompanying centralization of power favored by Secretary of the Treasury Alexander Hamilton. Along with Thomas Jefferson, Madison organized the Democratic-Republican Party, which was, alongside Hamilton's Federalist Party, one of the nation's first major political parties. After Jefferson won the 1800 presidential election, Madison served as Secretary of State from 1801 to 1809. In that position, he supervised the Louisiana Purchase, which doubled the size of the United States. Unlike most college-bound Virginians of his day, Madison did not attend the College of William and Mary, where the lowland Williamsburg climate - thought to be more likely to harbor infectious disease - might have strained his delicate health. Instead, in 1769, he enrolled at the College of New Jersey (now Princeton University).His studies at Princeton included Latin, Greek, theology, and the works of the Enlightenment.