[Effects of warming needle moxibustion on improvement of gastrointestinal and immune function in patients with postoperation of colorectal cancer]. Insomnia due to deficiency of both the heart and spleen treated by acupuncture-moxibustion and Chinese tuina. The effectiveness of moxibustion for the treatment of functional constipation: a randomized, sham-controlled, patient blinded, pilot clinical trial Comparison of heat-sensitive moxibustion versus fluticasone/salmeterol (seretide) combination in the treatment of chronic persistent asthma: design of a multicenter randomized controlled trial [Observation on therapeutic effect of acupuncture and moxibustion on hyperemesis gravidarum]. Acupuncture for Chronic Pain in Japan: A Review [Post-stroke depression treated with acupuncture and moxibustion: an evaluation of therapeutic effect and safety]. Side-effects of moxibustion for cephalic version of breech presentation. [Observation on therapeutic effect of acupuncture at "cervical three points" combined with cake-separated moxibustion on cervical hyperosteogeny]. [Observation on clinical effects of moxibustion stimulation of different sensitive status acupoints for knee osteoarthritis]. The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Moxibustion Treatment for Knee Osteoarthritis: A Multi-Centre, Non-Blinded, Randomised Controlled Trial on the Effectiveness and Safety of the Moxibustion Treatment versus Usual Care in Knee Osteoarthritis Patients Cardiovascular effects of acupuncture stimulation at point Governing Vessel 26 in halothane-anesthetized ponies. [Chronic neck pain of cervical spondylosis treated with acupuncture and moxibustion in terms of the heart and kidney theory: a randomized controlled trial]. [Treatment of knee osteoarthritis with acupuncture and moxibustion: a randomized controlled trial]. Effects of infrared laser moxibustion on cancer-related fatigue in breast cancer survivors Observation of the efficacy of acupuncture and moxibustion in 62 cases of chronic colitis. Symptom Management for Irritable Bowel Syndrome: A Pilot Randomized Controlled Trial of Acupuncture/Moxibustion Efficacy and safety of ginger-salt-indirect moxibustion for urge urinary incontinence after stroke: protocol for a pilot multicentre randomised controlled trial [Controlled study on treatment of cervical spondylopathy of the nerve root type with acupuncture, moxibustion and massage as main]. Influence of Acupuncture on the Outcomes of in Vitro Fertilisation When Embryo Implantation Has Failed: A Prospective Randomised Controlled Clinical Trial [Study on effect of moxibustion and guben yiliu III combined with chemotherapy in treating middle-late stage malignant tumor]. The different immunomodulation of indirect moxibustion on normal subjects and patients with systemic lupus erythematosus.
OBJECTIVE To verify the clinical therapeutic effect of warming needle moxibustion on improvement of the gastrointestinal and immune function in patients with postoperation of colorectal cancer . METHODS One hundred and five patients with postoperation of colorectal cancer were r and omly divided into an acupuncture and moxibustion group , a Chinese medicine group and a routine treatment group , 35 cases in each group . They were all treated with gastrointestinal decompression and fluid replacement after operation . The acupuncture and moxibustion group was also treated with warming needle moxibustion on the 1st day after operation , and Zusanli ( ST 36 ) , Shangjuxu ( ST 37 ) and Xiajuxu ( ST 39 ) etc . were selected , once a day for 10 days , and the Chinese medicine group with Simo Decoction oral solution , three times daily for 10 days . The gastrointestinal function , peripheral blood components and changes of T lymphocyte and NK cells in postoperative patients were observed . RESULTS The time of the first bowel sound , exhaust and defecation in the acupuncture and moxibustion group were all shorter than those in the Chinese medicine group and the routine treatment group ( P<0.05 , P<0.01 ) . On the 10th day after operation , the percentages distribution of lymphocyte and neutrophil in the acupuncture and moxibustion group were better than those in the Chinese medicine group and the routine treatment group ( all P<0.05 ) . The acupuncture and moxibustion group was also superior to the Chinese medicine group and the routine treatment group in improving the subgroup of T lymphocyte , NK cells and the digestive system symptoms ( all P<0.05 ) . CONCLUSION Warming needle moxibustion has a good therapeutic effect on gastrointestinal function and can regulate bidirectionally peripheral blood lymphocyte and neutrophile granulocyte and improve the T lymphocyte subgroup and NK cells so as to promote the recovery of immune function in patients with colorectal cancer after operation OBJECTIVE To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen . METHODS 92 cases were divided r and omly into the treatment group ( treated by acupuncture-moxibustion and Chinese Tuina ) and the control group ( treated by acupuncture-moxibustion ) . RESULTS The therapeutic effect of the treatment group was obviously superior to that of the control group ( the CHI2 test showed P < 0.01 ) . CONCLUSIONS The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen Background Moxibustion is an ancient traditional medicine using burning mugworts to stimulate acupuncture points . The aim of this study was to investigate the safety and efficacy of moxibustion for the treatment of constipation using a r and omized , sham-controlled , participant-blinded , pilot trial . Methods Twenty-six participants ( identified with either qi ( vital energy ) deficiency or qi excess syndrome ) were r and omly divided into either a moxibustion or sham group . Participants were treated with real or sham moxibustion at 4 acupuncture points , ST23 and ST27 , bilaterally , 3 times per week for four weeks . The primary outcome was the frequency of defecations ; secondary outcomes were the Bristol stool form scale ( BSS ) and the constipation assessment scale ( CAS ) . Results Of the 26 participants that were r and omized , 24 completed the study .  Defecation frequency , BSS , and CAS showed no difference between the moxibustion and sham groups . The differences were -0.25 ( 95 % CI : -2.08 , 1.58 , p = 0.78 ) , -1.22 ( 95 % CI : -2.7 , 0.26 , p = 0.1 ) , 0.91 ( 95 % CI : -1.46 , 3.28 , p = 0.44 ) in defecation frequency , BSS , CAS , respectively . The defecation frequency increased from an average of 3.3 to 4.6 times per week in the moxibustion group ( 1.5[-0.5 , 2 ] , p = 0.06 ) and from 2.7 to 3.7 stools per week in the sham group ( 1[-1 , 2 ] , p = 0.15 ) after four weeks of treatment . The difference between participants with a deficiency or an excess syndrome , determined based on assessment of sweat , facial features , pain , body energy , and pulse type , was significant in only defecation frequency . The difference was 3.3 ( 95 % CI : 0.41 , 6.19 , p = 0.03 ) . Conclusion Moxibustion treatment appears safe , but showed no positive effect on constipation . The effectiveness of moxibustion treatment may depend on the syndrome pattern , and further long-term studies with a larger number of subjects are warranted . Trial registration Clinical Research Information Service , Background Asthma is a major health problem and has significant mortality around the world . Although the symptoms can be controlled by drug treatment in most patients , effective low-risk , non-drug strategies could constitute a significant advance in asthma management . An increasing number of patients with asthma are attracted by acupuncture and moxibustion . Therefore , it is of importance that scientific evidence about the efficacy of this type of therapy is regarded . Our past research es suggested heat-sensitive moxibustion might be effective in treatment of asthma . Our objective is to investigate the effectiveness of  heat-sensitive moxibustion  compared with conventional drug treatment . Methods / Design This study is comprised of a multi-centre ( 12 centers in China ) , r and omized , controlled trial with two parallel arms ( A : heat-sensitive moxibustion ; B : conventional drug ) . Group A selects heat- sensitive acupoints from the rectangle region which consist of two outer lateral lines of dorsal Bladder Meridian of Foot-Taiyang , and two horizontal lines of BL13(Fei Shu ) and BL17 ( Ge Shu);6 inch outer the first and second rib gap of anterior chest . Group B treats with fluticasone/salmeterol ( seretide ) . The outcome measures will be assessed over a 3-month period before each clinic visit at days 15 , 30 , 60 , and 90 . Follow-up visit will be at 3 , 6 months after the last treatment session . Adverse event information will be collected at each clinic visit . Discussion This trial will utilize high quality trial method ologies in accordance with CONSORT guidelines . It may provide evidence for the effectiveness of heat-sensitive moxibustion as a treatment for chronic moderate persistent asthma . Moreover , the result may propose a new type moxibustion to control asthma . Trial Registration The trial is registered at Chinese Clinical Trials Registry : OBJECTIVE To search for the best method for treatment of hyperemesis gravidarum . METHODS One hundred and fifty cases of hyperemesis gravidarum were r and omly divided into 3 groups , acup-moxibustion group , Chinese drug group and Western medicine group , 50 cases in each group . The acup-moxibustion group were treated with acupuncture at Zhongwan ( CV 12 ) , Neiguan ( PC 6 ) , Zusanli ( ST 36 ) and Yinlingquan ( SP 9 ) , and after arrival of qi , mild warming moxibustion of 10 - 15 min was added ; the Chinese drug group with oral administration of modified Suye Huanglian Decoction , and the Western medicine group with oral administration of phenobarbital and supplement of water and electrolyte . RESULTS The total effective rate was 86.0 % in the acup-moxibustion group , 42.0 % in the Chinese drug group and 38.0 % in the Western medicine group with a significant difference among the 3 groups ( P < 0.05 ) , the therapeutic effect in the acup-moxibustion group being the best . CONCLUSION Acup-moxibustion is the best method for hyperemesis gravidarum Many Japanese reports of acupuncture and moxibustion for chronic pain are not listed in medical data bases such as Medline . Therefore , they are not easily accessible to research ers outside of Japan . To complement existing review s of acupuncture and moxibustion for chronic pain and to provide more detailed discussion and analysis , we did a literature search using ‘ Igaku Chuo Zasshi We d ’ ( Japana Centra Revuo Medicina ) and ‘ Citation Information by National Institute of Information ’ covering the period 1978–2006 . Original articles and case reports of acupuncture and moxibustion treatment of chronic pain were included . Animal studies , surveys , and news articles were excluded . Two independent review ers extracted data from located articles in a pre-defined structured way , and assessed the likelihood of causality in each case . We located 57 papers written in Japanese ( 20 full papers , 37 case reports ) . Conditions examined were headache ( 12 trials ) , chronic low back pain ( 9 trials ) , rheumatoid arthritis ( 8 trials ) , temporom and ibular dysfunction ( 8 trials ) , katakori ( 8 trials ) and others ( 12 trials ) . While 23 were described as clinical control trials ( CCTs ) , 11 employed a quasi-r and om method . Applying the 5-point Jadad quality assessment scoring system , the mean score was 1.5 ± 1.3 ( SD ) . Eleven ( 52 % ) of the CCTs were conducted to determine a more effective procedure for acupuncture ; these compared a certain type of acupuncture with another type of acupuncture or specific additional points . In particular , the trigger point acupuncture was widely used to treat chronic low back pain in Japan . Many reports of chronic pain treatment by acupuncture and moxibustion are listed in Japanese data bases . From the data , we conclude that there is limited evidence that acupuncture is more effective than no treatment , and inconclusive evidence that trigger point acupuncture is more effective than placebo , sham acupuncture or st and ard care OBJECTIVE To evaluate the efficacy and safety of acupuncture and moxibustion in the treatment of post-stroke depression ( PSD ) by regulating the liver and strengthening the root prescription . METHODS In light of the r and om controlled trial principle , 123 cases were r and omized into an acupuncture-moxibustion group ( 42 cases ) , a medication group ( 40 cases ) and an acupuncture + medication group ( 41 cases ) . In the acupuncture-moxibustion group , the therapy of regulating the liver and strengthening the root was applied . Acupuncture was given at Hegu ( LI 4 ) , Taichong ( LR 3 ) , Baihui ( GV 20 , Yintang ( GV 29 ) , etc . The granule moxibustion was applied at Zhongwan ( CV 12 ) , Xiawan ( CV 10 ) , Guanyuan ( CV 4 ) and Qihai ( CV 6 ) . The treatment was given once a day and stopped in weekend . In the medication group , paroxetine hydrochloride tablets were prescribed for oral administration , 20 mg each day after breakfast . In the acupuncture + medication group , the therapies were adopted as the acupuncture-moxibustion group and the medication group . In the 2nd and 4th week of treatment , HAMD was used as the primary index and Barthel index as the secondary one for the efficacy assessment in the three groups respectively . The spleen and stomach syndrome scale of TCM was used for the assessment of TCM syndrome efficacy . Treatment emergent symptom scale ( TESS ) was applied for the safety assessment . RESULTS In the 4th week of treatment , the markedly effective rates were 69.0 % ( 29/42 ) , 65.0 % ( 26/40 ) and 70.7 % ( 29/41 ) in the acupuncture-moxibustion group , the medication group and the acupuncture + medication group respectively . The efficacies of anti-depression were similar in comparison among groups ( P > 0.05 ) . In the 2nd week of treatment , the improvement of HAMD score was significant in the acupuncture + medication group as compared with that before treatment and in comparison with the medication group ( P < 0.05 , P < 0.01 ) . As for improving Barthel index , reducing the spleen and stomach symptom score of TCM and decreasing the score of TESS , the results in the acupuncture-moxibustion group and the acupuncture + medication group were superior to those in the medication group ( P < 0.05 , P < 0.01 ) . CONCLUSION The therapy of acupuncture and moxibustion with regulating the liver and strengthening the root achieves the definite efficacy of anti-depression and presents the quite high safety in treatment OBJECTIVES Moxibustion , a Traditional Chinese Medicine technique related to acupuncture , was proposed to facilitate cephalic version of breech presentation . Several trials were conducted to evaluate the efficacy , but there are few reports on the safety of moxibustion . Our objective was to assess the side-effects and acceptability of this intervention . DESIGN We are conducting a r and omized controlled trial to evaluate the efficacy of moxibustion for breech version . The first 12 participants r and omized in the moxibustion group had additional fetal surveillance by electronic monitoring . SUBJECTS Pregnant women with a fetus in breech presentation are included in the trial between 34 and 36 weeks of gestation . INTERVENTIONS We performed a cardiotocogram during 10 minutes before , 20 minutes during , and 10 minutes after each session . A maximum of 9 sessions were scheduled every other day , and stopped when cephalic version was diagnosed . The recordings were assessed by 3 independent readers using the Fischer scoring system . OUTCOME MEASURES Fetal well-being was evaluated by the cardiotocogram ; effect on the mother was evaluated by blood pressure recorded before and after each session ; maternal views , contractions , and perceived changes in fetal movements were assessed using a question naire . RESULTS A total of 65 cardiotocograms were analyzed . All scores were considered as normal , being at 8 or more on a 0 - 10 scale . Acceptability for the women and compliance to the intervention were good . No significant maternal or fetal side-effect was observed . CONCLUSIONS We have not detected alterations of fetal and maternal well-being or other side-effects associated with moxibustion applied to the BL 67 for cephalic version of breech presentations . Moxibustion appears to be safe for both the mother and the fetus OBJECTIVE To compare therapeutic effects of acupuncture at " cervical three points " combined with cake-separated moxibustion and routine acupuncture at Jiaji ( EX-B 2 ) on cervical hyperosteogeny . METHODS Single blind , r and omized and controlled methods were used and 91 cases were divided into an observation group of 46 cases and a control group of 45 cases . The observation group was treated by acupuncture at " cervical three points " combined with cake-separated moxibustion , i.e. acupuncture at Chonggu ( EX ) , Dazhui ( GV 14 ) , Taodao ( GV 13 ) and moxibustion at pain points with cake made by Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba ; the control group was treated with acupuncture at Jiaji ( EX-B 2 ) . Changes of sourness and pain of the neck , the shoulder and back , pressure pain and cervical activity scores were used for assessment of therapeutic effects . RESULTS The markedly cured rate of 76.1 % in the observation group was better than 42.2 % in the control group ( P<0.05 ) . After treatment , the scores of all the items were significantly improved in the two groups ( all P<0.05 ) , and the observation group in sourness and pain of the neck , the shoulder and back , and cervical activity were better than the control group ( all P<0.05 ) . CONCLUSION The therapeutic effect of acupuncture at " cervical three points " combined with cake-separated moxibustion on cervical hyperosteogeny is superior to routine acupuncture at Jiaji ( EX-B 2 ) OBJECTIVE To observe the clinical effect of moxibustion of different acupoints undergoing heat-sensitive state and resting state in the treatment of knee osteoarthritis ( KOA ) patients . METHODS A total of 60 cases of KOA patients were enrolled in the present trial . They were divided into heat-sensitive moxibustion ( heat-sensitive ) group and non-sensitive moxibustion group ( resting group ) . Moxibustion was applied to Neixiyan ( EX-LE 4 ) , Waixiyan ( i.e. Dubi , ST 35 ) and Heding ( EX-LE 2 ) for about 45 min , once daily for 20 days . The heat-sensitive state was evaluated according to the patient 's feeling . After moxibustion stimulation at the acupoint area , if the patient feels the heat penetrating from the skin surface to the deep tissue , or/ and extending peripherally around the moxibustion site , or/ and transmitting toward a certain direction , it is considered to be heat sensitization state . The therapeutic effect was evaluated by using visual analogue scale ( VAS ) for pain severity changes and by Guiding Principles for Clinical Trials of New Drugs of Chinese Materia Medica for evaluating functional activity of the knee-joint . RESULTS After 20 sessions of treatment and after a half year 's follow-up , the total integrated scores of VAS in the heat-sensitive group were all lower than those of the resting group ( P < 0.01 ) . Following 20 sessions of treatment , of the two 30 KOA patients in the heat-sensitive group and resting group , 14 ( 46.67 % ) and 5 ( 16.67 % ) experienced a marked improvement , 10 ( 33.33 % ) and 9 ( 30.00 % ) were effective , 6 ( 20.00 % ) and 16 ( 53.33 % ) were invalid , with the effective rates being 80.00 % and 46.67 , respectively . Half-year 's follow-up showed that the effective rates of the heat-sensitive group and resting group were 79.17 % ( 19/24 ) and 42.86 % ( 6/14 ) , respectively , suggesting a better therapeutic effect of heat-sensitive moxibustion . CONCLUSION The clinical n effect of heat-sensitive moxibustion is significantly superior to that of non-sensitive moxibustion in the treatment of KOA patients , being worthy of clinical application Acupuncture , one of the Oriental medical therapeutic techniques that can be traced back at least 2500 years , is growing in popularity all over the world . Korea has continued to develop its own unique tradition of medicine throughout its long history , and has formed different types of acupuncture methods . The purpose of this review is to summarize clinical case studies in acupuncture and related therapies , such as acupressure , electric acupuncture , auricular acupuncture and moxibustion in Korea . A survey of Korean journals revealed that a total of 124 studies were published from 1983 to 2001 . Results obtained from the survey showed that most clinical studies using acupuncture , electric acupuncture , moxibustion and other traditional therapies could alleviate a relatively broad range of medical problems . However , it should be emphasized that almost all clinical case studies published in various local journals did not follow the ‘ good clinical practice ’ with respect to regulatory aspects . Since they were not conducted using the r and omized double-blinded controls with a large sample size , all the results should be considered as therapeutic indications . This review is an attempt to show the scope of acupuncture in our country and the kind of diseases , after many years of clinical experience , that were deemed valid targets for clinical trials Introduction This study tested the effectiveness of moxibustion on pain and function in chronic knee osteoarthritis ( KOA ) and evaluated safety . Methods A multi-centre , non-blinded , parallel-group , r and omised controlled trial compared moxibustion with usual care ( UC ) in KOA . 212 South Korean patients aged 40–70 were recruited from 2011–12 , stratified by mild ( Kellgren/Lawrence scale grade s 0/1 ) and moderate-severe KOA ( grade s 2/3/4 ) , and r and omly allocated to moxibustion  or UC  for four weeks . Moxibustion involved burning mugwort devices over acupuncture and Ashi points in affected knee(s ) . UC was allowed . Korean Western Ontario and McMaster Universities Question naire ( K-WOMAC ) , Short Form 36 Health Survey ( SF-36v2 ) , Beck Depression Inventory ( BDI ) , physical performance test , pain numeric rating scale ( NRS ) and adverse events were evaluated at 5 and 13 weeks . K-WOMAC global score at 5 weeks was the primary outcome . Results 102 patients ( 73 mild , 29 moderate-severe ) were allocated to moxibustion , 110 ( 77 mild , 33 moderate-severe ) to UC . K-WOMAC global score ( moxibustion 25.42+/−SD 19.26 , UC 33.60+/−17.91 , p<0.01 , effect size = 0.0477 ) , NRS ( moxibustion 44.77+/−22.73 , UC 56.23+/−17.71 , p<0.01 , effect size = 0.0073 ) and timed-st and test  ( moxibustion 24.79+/−9.76 , UC 25.24+/−8.84 , p = 0.0486 , effect size = 0.0021 ) were improved by moxibustion at 5 weeks . The primary outcome improved for mild but not moderate-severe KOA . At 13 weeks , moxibustion significantly improved the K-WOMAC global score and NRS .  Moxibustion  improved SF-36 physical component summary ( p = 0.0299 ) , bodily pain ( p = 0.0003 ) , physical functioning ( p = 0.0025 ) and social functioning ( p = 0.0418 ) at 5 weeks , with no difference in mental component summary at 5 and 13 weeks . BDI showed no difference ( p = 0.34 ) at 5 weeks . After 1158 moxibustion treatments , 121 adverse events included first ( n = 6 ) and second degree ( n = 113 ) burns , pruritus and fatigue ( n = 2 ) . Conclusions Moxibustion may improve pain , function and quality of life in KOA patients , but adverse events are common . Limitations included no sham control or blinding . Trial Registration Clinical Research Information Service ( CRIS ) The acupuncture point Governing Vessel ( GV-26 ) is used commonly in the Orient to treat shock in human beings and other species . The cardiovascular effects of stimulation of GV-26 were studied in healthy ponies during 2 episodes of halothane anesthesia .  During one anesthetic episode , electrical stimulation ( electrostimulation ) of GV-26 was performed , and during the other anesthetic episode , heat stimulation ( moxibustion ) of GV-26 was performed . The order of the stimulations was r and om . A nonacupuncture point was selected for comparable control stimulation during each experiment . Control and acupuncture stimulations were of equal intensity . There were no significant changes in cardiac output , systemic arterial pressure , or heart rate associated with either electrical or heat acupuncture stimulation OBJECTIVE To evaluate the clinical efficacy of acupuncture and moxibustion on chronic neck pain of cervical spondylosis in terms of the heart and kidney theory . METHODS One hundred and eleven cases were r and omized into a heart-kidney acupuncture group ( 55 cases ) and a conventional acupuncture group ( 56 cases ) . In the heart-kidney acupuncture group , acupuncture was applied to Bailao ( EX-HN 15 ) , Shenmen ( HT 7 ) and Wangu ( SI 4 ) . Afterwards , the direct moxibustion was applied to Dazhui ( GV 14 ) , Xinshu ( BL 15 ) and Shenshu ( BL 23 ) . After moxibustion , the intradermal needling therapy was provided at Bailao ( EX-HN 15 ) , Xinshu ( BL 15 ) and Shenshu ( BL 23 ) . In the conventional acupuncture group , acupuncture was applied to Bailao ( EX-HN 15 ) and Zhongzhu ( TE 3 ) at first . Afterwards , the direct moxibustion was done at Dazhui ( GV 14 ) , Bailao ( EX-HN 15 ) and Jianzhongshu ( SI 15 ) . After moxibustion , the interdermal needling therapy was provided at Bailao ( EX-HN 15 ) and Jianzhongshu ( SI 15 ) . The northwick park pain question naire ( NPQ ) was adopted as the main efficacy index for the evaluation . RESULTS After the intervention and during the follow-up visit period , NPQ scores were all reduced remarkably as compared with those before the intervention for the patients in two groups ( all P < 0.001 ) , but the differences were not statistically significant in groups ( all P > 0.05 ) . By the age stratification analysis for the patients in two groups , the program in terms of the heart and kidney theory achieved the superior efficacy for the patients over 45 years old as compared with those in the conventional acupuncture group ( P < 0.05 , P < 0.01 ) . By the stratification analysis of the sick duration , the program in terms of the heart and kidney theory achieved the superior efficacy for the patients with over 7 years sick duration as compared with those in the conventional acupuncture group ( P < 0.05 , P < 0.01 ) . CONCLUSION The acupuncture and moxibustion therapeutic program in terms of the heart and kidney theory achieves the superior efficacy on chronic pain of cervical spondylosis for the patients over 45 years old and with over 7 years sick duration . It is one of the optimized programs for the treatment of this disease OBJECTIVE To compare the difference of the efficacy on  knee osteoarthritis ( KOA )  between the combined therapy of acupuncture and moxibustion and western medication , and explore the better therapeutic method for KOA . METHODS One hundred and sixty patients were divided into a combined therapy group and a western medication group , 80 cases in each one according to the visit sequence , with the r and om number table adopted . In the combined therapy group , the main points were selected from the local painful sites , combined with the acupoints based on the syndrome differentiation and distal acupoints on the affected meridians . The lifting , thrusting or rotating technique was used and the reinforcing or reducing manipulation was applied according to the syndrome differentiation . " Duanci " or " Shuci " needling technique was used specially at the extra points and Ashi points . The needling sensation relied on the patients ' tolerance . After acupuncture , the heat-sensitive moxibustion with pure moxa stick was applied over the local painful sites around knee joint and Shenshu ( BL 23 ) to detect the heat-sensitized points . Acupuncture and moxibustion were given once every day . The treatment of 5 days made 1 session . There were 2 days at the interval between two sessions . In the western medication group , glucosamine sulfate capsules were prescribed for oral administration , 2 capsules each time , three times a day . Additionally , the joint cavity injection was combined . On the first day , sodium hyaluronate 25 mg and triamcinolone acetonide acetate 50 mg were injected . Afterwards , on the 8th , 15th , 22nd and 29th days , sodium hyaluronate injection 25 mg was used only . The treatment was for 5 weeks totally in the two groups . The efficacy was analyzed statistically in 5 weeks . The follow-up visit was conducted in 3 months and 6 months after 5 weeks treatment , respectively . The Western Ontario and Mcmaster Universities Osteoarthritis Index ( WOMAC ) and visual analogue scale ( VAS ) were adopted to assess the recovery of joint function . RESULTS The efficacy in 5 weeks of treatment was different significantly between the two groups ( P < 0.05 ) . The efficacy in the western medication group was better than that in the combined therapy group . The difference in the safety assessment was remarkable ( P < 0.01 ) . The result in the combined therapy group was superior remarkably to the western medication group . In 3-month follow-up visit after treatment , the knee joint function was not different obviously between the two groups ( P > 0.05 ) . In 6-month followup visit after treatment , the knee joint function was different obviously between the two groups ( P < 0.01 ) . The result in the combined therapy group was better remarkably than that in the western medication group . CONCLUSION The combined therapy of acupuncture and moxibustion achieves the safe and effective therapeutic effect with less adverse reactions in the treatment of KOA . The immediate effect in the combined therapy group is not so obvious as compared with the western medication , but the long-term efficacy is remarkably superior to western medication Abstract Background : Cancer-related fatigue ( CRF ) is the most common and distressing symptom associated with cancer treatment that breast cancer survivors ( BCS ) experience . We previously found that laser moxibustion may be efficacious for CRF . The primary aim of this study is to determine the specific efficacy of 10.6 μm infrared laser moxibustion on CRF . The secondary aim is to evaluate the effect of infrared laser moxibustion on co-existing symptoms that BCS experience . Methods : We will conduct a r and omized , sham-controlled , three-arm trial of infrared laser moxibustion ( ILM ) against sham ILM ( SILM ) and waitlist control ( WLC )  among BCS with moderate to severe fatigue . The two intervention groups will receive either real or sham infrared laser moxibustion on four acupoints ( i.e. , ST36 [ bilateral ] , CV4 , and CV6 ) for 20 minutes each session for 6 weeks ( twice per week ) . The primary endpoint is the change in fatigue score from Baseline to Week 6 as measured by the Chinese version of the Brief Fatigue Inventory ( BFI-C ) . Our secondary aim is to compare the severity of co-morbidities ( e.g. , depression , insomnia , and pain ) among the 3 groups . Discussion : The results of our trial will establish evidence for the efficacy of infrared laser moxibustion for CRF , a very common and challenging symptom . Trial registration number : NCT03553355 62 patients with chronic colitis were r and omly divided into two groups . Acupuncture and moxibustion at acupoints such as Tianshu ( St 25 ) , Guanyuan ( Ren 4 ) were applied in the treatment group , and western drugs were applied in the control group . The results showed that acupuncture and moxibustion had a marked curative effective with few side effects , and therefore was readily acceptable to the patients The purpose of this pilot study was to assess the effect of an individualized traditional Chinese medicine ( TCM ) acupuncture and moxibustion ( Acu/Moxa ) treatment on symptom control in patients with irritable bowel syndrome ( IBS ) in a preliminary , r and omized , sham/placebo-controlled trial . Twenty-nine men and women with IBS were r and omized to either  individualized Acu/Moxa (  treatment  group ) or sham/placebo Acu/Moxa ( control group ) . All subjects were assessed by a diagnostic acupuncturist for a TCM evaluation and individualized point prescription . Only those subjects assigned to the experimental group received the individually prescribed treatment . The diagnostic acupuncturist did not administer treatments and was blind to treatment assignments . All subjects kept a symptom diary for the duration of the study , enabling measurement of symptom frequency , severity , and improvement . The Clinical Global Impression Scale was administered preintervention to establish baseline severity and on completion of the 4-week , eight-session treatment intervention . After 4 weeks of twice-weekly Acu/Moxa treatment , average daily abdominal pain/discomfort improved whereas the control group showed minimal reduction . This between-group difference adjusted for baseline difference was statistically significant . The intestinal gas , bloating , and stool consistency composite score showed a similar pattern of improvement . The findings indicate that Acu/Moxa treatment shows promise in the area of symptom management for IBS Introduction Ginger-salt-indirect moxibustion is widely applied to treat urge urinary incontinence after stroke , which is a common complication in stroke survivors . Moxa cone moxibustion and moxa box moxibustion are the main techniques of ginger-salt-indirect moxibustion . Our previous study had shown that ginger-salt-indirect moxibustion using moxa cones was feasible and effective for urination disorders post-stroke . This pilot study aims to assess the feasibility of conducting research to evaluate the efficacy and safety of ginger-salt-indirect moxibustion for patients with post-stroke urge urinary incontinence . Methods and analysis This is a multicentre , prospect i ve , single-blinded , pilot r and omised controlled trial . 120 eligible patients will be r and omly allocated to three groups . Treatment group A ( n=40 ) will receive moxa cone moxibustion and routine care ; treatment group B ( n=40 ) will receive moxa box moxibustion and routine care ; control group ( n=40 ) will only receive routine care for stroke recovery . The entire moxibustion treatment will consist of a total of 28 sessions during the course of 4 weeks . The primary outcome measure will be the increase in mean volume per void assessed at week 4 from the first moxibustion session ( baseline ) . Secondary outcome measures will include mean frequency of urination per day and quality of life assessment s measured by completion of the Incontinence Quality of Life Question naire and Barthel Index . All outcome measures will be assessed at baseline and at 4 and 16 weeks from baseline . Adverse events in the three groups will be recorded to assess the safety of moxibustion . Ethics and dissemination Research ethics was approved by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University ( ref : 2013BL-094 ) . Written informed consent will be obtained from all participants . Study results will be published in peer review ed journals . Trial registration number IS RCT N 44706974 OBJECTIVE To probe into clinical value of comprehensive program of acupuncture , moxibustion and massage as main for treatment of cervical spondylopathy of the nerve root type . METHODS Five centers , single blind , r and omized controlled method were used , 660 cases were divided into a treatment group of 317 cases and a control group of 311 cases . They were treated respectively with comprehensive program of acupuncture , moxibustion and massage as main , and comprehensive program of physical therapy as main . Establish syndrome detection scale and multiply dimensional effect assessment indexes , and evaluate the therapeutic effects and safety . RESULTS The cured rate , the cured-markedly effective rate were 42.9 % , 64.4 % in the treatment group , respectively , better than 16.7 % , 36.3 % in the control group ( P<0.01 ) ; after treatment of 2 weeks , clinical symptoms improved in the both groups , but the treatment group was better than the control group in the improvement degrees of neck-shoulder-limb pain , neck rigidity , abnormality of cervical anteflexion , etc . ( P<0.01 or P<0.05 ) ; the treatment group was shorter than the control group in the time of producing the effect and therapeutic course ( P<0.01 ) . CONCLUSION Comprehensive program of acupuncture , moxibustion and massage as main is safe and effective for treatment of cervical spondylopathy , with a better therapeutic effect compared with the comprehensive program of physical therapy Objective To evaluate the effectiveness of acupuncture and moxibustion as an adjuvant treatment in women undergoing in vitro fertilisation ( IVF ) when embryo implantation has failed . Methods A prospect i ve , r and omised controlled clinical trial was conducted with 84 infertile patients who had had at least two unsuccessful attempts of IVF . The patients were r and omised in three groups : control ( n=28 ) , sham ( n=28 ) and acupuncture ( n=28 ) . The sample size was calculated by assuming a pregnancy rate of 10 % when embryo implantation had failed . The pregnancy rates of the current IVF cycle were evaluated by measurement of blood β human chorionic gonadotrophin ( βhCG ) and subsequent transvaginal ultrasound .  Acupuncture was performed on the first and seventh day of ovulation induction , on the day before ovarian puncture and on the day after embryo transfer . In the acupuncture group , patients were treated with moxibustion at nine acupuncture points ( BL18 , BL22 , BL23 , BL52 , CV3 , CV4 , CV5 , CV7 , GV4 ) and needling at 12 points . In the sham group needles were inserted in eight areas that did not correspond to known acupuncture points . Results The clinical pregnancy rate in the acupuncture group was significantly higher than that in the control and sham groups ( 35.7 % vs 7.1 % vs 10.7 % ; p=0.0169 ) . Conclusions In this study , acupuncture and moxibustion  increased pregnancy rates when used as an adjuvant treatment in women undergoing IVF , when embryo implantation had failed OBJECTIVE To observe the complementary function of moxibustion and Guben Yiliu III ( GBYL ) , a Chinese herbal composite preparation , in combination with chemotherapy . METHODS Eighty-one patients of middle-late stage malignant tumor were r and omly divided into three groups , 16 in the control group treated with chemotherapy alone , 35 in the TCM group treated with chemotherapy combined GBYL and 30 in the TCM combined moxibustion group . The therapeutic effect of treatment was evaluated according to the immediate effect , living quality scoring , etc . RESULTS The comprehensive living quality score and Karnofsky score dropped significantly in the control group after treatment with significant increase of pain score and decrease of tongue figure score ( P < 0.05 or P < 0.01 ) . In the TCM group , the former two criteria lowered less than those in the control group , but no significant difference in the latter two criteria was shown . For those in the TCM combined moxibustion group , all the four criteria were improved better than those in the control group ( P < 0.01 or P < 0.05 ) . CONCLUSION GBYL combined or not combined with moxibustion could improve the living quality of patients received chemotherapy Moxibustion has been thought to enhance immunity in healthy condition , but suppress abnormal immune response in disease status . We collected 12 patients with systemic lupus erythematosus ( SLE ) and 12 healthy women who received indirect moxibustion on acupuncture points ST-36 ( Zusanli ) and SP-6 ( Sanyinjiao ) 20 minutes per day for 1 week . During the course , there were no changes of their regular medications or intercurrent infections in normal subjects and SLE patients . We found that indirect moxibustion for 1 week could elevate CD3 + and CD4 + T-lymphocytes in normal subjects , whereas decrease relative proportions of CD8 + T-lymphocytes in patients with SLE . This result confirms that indirect moxibustion has different immunomodulation in normal condition and autoimmune status . However , whether immunomodulatory effects of indirect moxibustion are beneficial for normal subjects and patients with SLE require further confirmation
Conclusion The evidence is limited to suggest moxibustion is an effective supportive cancer care in nausea and vomiting .
Background Moxibustion is a traditional Chinese method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points .
Considering moxibustion is closely related to acupuncture , it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer .
The objective of this review was to systematic ally assess the effectiveness of moxibustion for supportive cancer care .