Albumin-Oleic Acid Treatment of Spinal Cord Injury Figure 6. Albumin-Oleic Acid Decreases Microglia Activation and Reduces NMDA NR1 Phosphorylation after SCI. Alb-OA treatment (C and F, 20x) reduced microglia reactivity (OX-42, B and E, 20x) observed after SCI within both dorsal laminae I–II (C) and lamina V (F) when compared to na¨ıve animals (A and D). Quantification of OX-42 area within laminae I–II (G) and lamina V (H) supported the qualitative inhibitory effect of Alb-OA treatment on increased microglia reactivity area following T9 contusion SCI when compared to na¨ıve animals. Alb-OA treatment (K, 10x) reduced the accentuated number of cells with NR1 NMDA receptor phosphorylation (pNR-1) within the dorsal horn observed after SCI (J, 10x) when compared to normal tissue (I). Quantification of pNR1-positive cell number within the dorsal laminae I–II (L) and lamina V (M) supported the inhibition of NMDA receptor phosphorylation with Alb-OA. 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