Deviance Detection in Rat Auditory Cortex Figure 6. Responses as a function of Df. A. LFP and the corresponding MUA responses to the two frequencies in a paradigm with Df = 10%. B. Df = 21% (from another animal). C. Df = 96% (another animal). Same conventions as in Fig. 4. doi:10.1371/journal.pone.0023369.g006 The model is inspired by models of adaptation by depletion of synaptic resources [18]. The relationship between the model which is heuristically developed below and a formal model of resource depletion is clarified in Text S1. The model assumes that each tone presentation depletes synaptic resources available to produce responses. The interplay between synaptic depletion and recovery during the silence between two stimuli (considered as fixed here, since only the data with ISI = 300 ms was modeled) Figure 7. Summary of the responses at all Df. A. The population average of normalized LFP responses to the six conditions for four different values of Df. B. Scatter plots of SI2 vs. SI1 for LFP data from all recording sites as a function of Df. C,D. Same as A,B, but for MUA data. The scatter plots of SI2 vs. SI1 at Df = 44% are those appearing in Fig. 2A, and have been replotted here as well for completeness. doi:10.1371/journal.pone.0023369.g007 PLoS ONE | www.plosone.org 7 August 2011 | Volume 6 | Issue 8 | e23369