Supporting Information Table S1 Shown are results from pathway analyses using SAFE to investigate KEGG pathways, GO keywords (BP = biological process, CC = cellular component, and MF = molecular function), and PFAM protein family groupings. These all had an empirical p- value (from permutation) ,0.005 and were composed of $10 transcripts. Found at: doi:10.1371/journal.pone.0005805.s001 (0.11 MB DOC) Figure S1 Quantile-quantile (QQ) plots from the planned paired analyses contrasting monozygotic (MZ) twins affected with chronic References 1. Fukuda K, Strauss SE, Hickie I, Sharpe MC, Dobbins JG, et al. (1994) The chronic fatigue syndrome: a comprehensive approach to its definition and study. Annals of Internal Medicine 121: 953–959. 2. Reeves WC, Lloyd A, Vernon SD, Klimas N, Jason LA, et al. (2003) Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution. BMC Health Serv Res 3: 25. 3. 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