Finch et al. Journal of Medical Case Reports 2012, 6:148 http://www.jmedicalcasereports.com/content/6/1/148 Authors’ contributions TF performed the histological examination of the ovary, and was the major contributor in writing the manuscript. CP performed the histological examination of the odontogenic keratocyst. KB performed the right salpingo- oophorectomy and followed our patient clinically. YEG performed the histological examination of the ovary. All authors read and approved the final manuscript. Acknowledgment We would like to acknowledge Dr Robert H. Young of Massachusetts General Hospital for consultation in this case. Author details 1Discipline of Laboratory Medicine, Faculty of Medicine, Memorial University, 300 Prince Philip DriveSt John’s, NL A1B 3V6, Canada. 2Janeway Children's Hospital and Rehabilitation Centre, Faculty of Medicine, Memorial University, 300 Prince Philip Drive, St John’s, NLA1B 3V6Canada. 3Discipline of Obstetrics and Gynecology, Faculty of Medicine, Memorial University, 300 Prince Philip Drive, St John’s, NLA1B 3V6Canada. Received: 6 January 2012 Accepted: 27 February 2012 Published: 12 June 2012 References 1. Gorlin RJ: Nevoid basal-cell carcinoma syndrome. Medicine (Baltimore) 1987, 66:98–113. 2. Evans DGR, Ladusans EJ, Rimeer S, Burnell LD, Thakker N, Farndon PA: Complications of the naevoid basal cell carcinoma syndrome: results of a population based study. J Med Genet 1993, 30:460–464. 3. Shanely S, Ratcliffe J, Hockey A, Haan E, Oley C, Ravine D, Martin N, Wicking C, Chenevix-Trench G: Nevoid basal cell carcinoma syndrome: review of 118 affected individuals. Am J Med Genet 1994, 50:282–290. 4. Gailani MR, Bale SJ, Leffell DJ, DiGiovanna JJ, Peck GL, Poliak S, Drum MA, Pastakia B, McBride OW, Kase R, Greene M, Mulvihille JJ, Bale AE: Developmental defects in Gorlin syndrome to a putative tumor suppressor gene on chromosome 9. Cell 1992, 69:111–117. 5. Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr, Scott MP: Human homolog of patched, a candidate gene for basal cell nevus syndrome. Science 1996, 272:1668–1671. 6. Kimonis VE, Goldstein AM, Pastakia B, Yang ML, Kase R, DiGiovanna JJ, Bale AE, Bale SJ: Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome. Am J Med Genet 1997, 69:299–308. 7. Khalifa MA, Patterson-Cobbs G, Hansen CH, Hines JF, Johnson JC: The occurrence of endometrial adenocarcinoma in a patient with basal cell nevus syndrome. J Natl Med Assoc 1997, 89:549–552. 8. Kraemer BB, Silva EG, Sneige N: Fibrsarcoma of ovary a new component in the nevoid basal-cell carcinoma syndrome. Am J Surg Pathol 1984, 8:231–236. 9. Chen YJ, Hsieh CS, Eng HL, Huang CC: Ovarian fibroma in a 7-month old infant: a case report and review of the literature. Pediatr Surg Int 2004, 20:894–897. 10. Roth LM, Czernobilsky B: Perspectives on pure ovarian stromal neoplasms and tumor-like proliferations of the ovarian stroma. Am J Surg Pathol 2011, 35:e15–e33. 11. Raggio M, Kaplan AL, Harberg JF: Recurrent ovarian fibromas with basal cell nevus syndrome (Gorlin syndrome). Obstet Gynecol 1983, 61(3 Suppl):95S–96S. 12. Seracchioli R, Bagnoli A, Colombo FM, Missiroli S, Venturoli S: Conservative treatment of recurrent ovarian fibromas in a young patient affected by Gorlin syndrome. Hum Reprod 2001, 16:1261–1263. doi:10.1186/1752-1947-6-148 Cite this article as: Finch et al.: Gorlin syndrome presenting with a unilateral ovarian fibroma in a 22-year-old woman: a case report. Journal of Medical Case Reports 2012 66:148148. Page 5 of 5 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color ﬁgure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit