Effectiveness Compliance Baseline Wed Tue+Thur Mon+Wed+ Fri 100% 90% 75% 50% 100% 90% 75% 50% 100% 90% 75% 50% 18.61 (18.54, 18.71) 16.53 (16.42, 16.64) 16.76 (16.60, 16.90) 17.10 (16.98, 17.21) 17.70 (17.54, 17.87) 14.43 (14.30, 14.58) 15.00 (14.87, 15.16) 15.73 (15.63, 15.83) 16.90 (16.79, 17.02) 5.49 (1.59, 6.88) 9.23 (8.11, 9.80) 11.92 (11.64, 12.27) 14.95 (14.72, 15.28) 0.00 0.11 0.10 0.08 0.05 0.22 0.19 0.15 0.09 0.69 0.50 0.36 0.20 Mao BMC Public Health 2011, 11:522 http://www.biomedcentral.com/1471-2458/11/522 Table 3 Sensitivity of discontinuous weekend-extension strategies to compliance levels R0 = 1.4 Overall attack rates % (95%CIa) Relative effectivenessb R0 = 2.0 Overall attack rates % (95%CI) 26.43 (26.36, 26.53) 25.67 (25.58, 25.75) 25.73 (25.67, 25.79) 25.86 (25.77, 25.95) 26.08 (26.01, 26.14) 24.77 (24.68, 24.84) 24.93 (24.83, 25.00) 25.23 (25.17, 25.29) 25.70 (25.62, 25.77) 21.41 (21.27, 21.52) 22.07 (21.95, 22.23) 23.00 (22.81, 23.11) 24.42 (24.32, 24.56) Page 7 of 10 Relative effectiveness 0.00 0.03 0.03 0.02 0.01 0.06 0.06 0.05 0.03 0.19 0.16 0.13 0.08 a95%CI stands for the 95% confidence intervals from 50 model realizations. bRelative effectiveness = (Baseline attack rate -Strategy-specific attack rate)/Baseline attack rate. Table 3 compares the overall attack rates and relative effectiveness resulted from three discontinuous weekend-extension strategies (Wed, Tue+Thur, and Mon +Wed+Fri). Sensitivity analysis was conducted on each strategy under five compliance levels of 0%, 50%, 75%, 90%, and 100%. a high intensity above 200 infections per km2. The ‘Tue +Thur’ strategy (Figure 6b) slightly changed the spatial patterns and produced small improvement as opposed to the ‘Wed’ extension strategy. The ‘Mon+Wed+Fri’ strategy (Figure 6c) eliminated infections in most parts of the suburb, but the CBD and transition zone remained at a moderate intensity of around 100 infections per km2. Geographically, this strategy failed to isolate the affected area into small clusters of infections. Shares of infections by location It is also noteworthy to compare how these weekend- extension strategies move the foci of infections between the four types of location, i.e., home, workplace, service Figure 6 Discontinuous weekend-extension strategies (2). Spatial patterns of infections resulted from the three discontinuous weekend- extension strategies given R0 = 1.4 and compliance level = 100%: (a) Wed, (b) Tue+Thur, and (c) Mon+Wed+Fri. Each 50 m × 50 m cell value indicates the total number of infections during the 200 days at the cell location (infections/per km2). All cell values are averages of 50 randomly seeded simulation runs.