International Journal of Pediatrics 5 Table 3: Immunophenotypic proﬁles of 275 de novo acute lymphoblastic leukaemia.∗ Markers T-cell ALL (n = 59) pB-cell ALL (n = 216)∗∗ CD1a+ 45/56 (80.4) — sCD3+ 49/59 (83.1) 0/216 (0.0) cCD3+ 57/57 (100) 0/216 (0.0) CD4+ 42/51 (82.4) — CD5+ 54/55 (98.2) — CD7+ 59/59 (100) 7/216 (3.2) CD8+ 32/52 (61.5) — CD10+ 10/47 (21.3) 197/216 (91.2) cyCD79a+ 0/48 (0.0) 162/162 (100) CD19+ 1/59 (1.7) 216/216 (100) CD20+ 0/8 (0.0) 26/48 (54.2) CD22+ 1/47 (2.1) 216/216 (100) CyIg+ — 18/58 (31.0) SIg+ — 2/58 (3.5) TdT+ 31/44 (70.5) 142/158 (89.8) CD34+ 25/59 (42.4) 160/216 (74.1) HLA-DR+ 4/39 (10.3) 152/155 (98.1) CD13+ 13/59 (22) 100/216 (46.3) CD33+ 9/49 (15.3) 75/216 (34.7) CD13+,CD33+ 2/59 (3.4) 51/216 (23.6) CD13−,CD33+ 7/59 (11.9) 24/216 (11.1) CD13+,CD33− 11/59 (18.6) 49/216 (22.7) CD13+ and/or CD33+ 20/59 (33.9) 124/216 (57.4) CD13−, CD33− 39/59 (66.1) 92/216 (42.6) CD45+ 59/59 (100) 187/216 (87) ALL: acute lymphoblastique leukaemia, −: not applicable, MPO: myeloperoxidase, TdT: terminal deoxynucleotidyl transferase, cy: cytoplasmique, s: surface, +: positive, −: negative, Ig: immunoglobulin. ∗Result are given as number positive/number tested (% positive). ∗∗Mature B-cell ALL excluded. Table 4: Clinical and biological features according to CD10 expression in children with ALL. No. of patients (%) pB-cell ALL (n = 216) Features Total of patients CD10− CD10+ Gender F 113 9 (9.09) 90 (90.91) M 150 10 (8.55) 107 (91.45) Leukocyte count (×109/L) <50 177 12 (4.71) 150 (92.59) >50 85 7 (13.21) 46 (86.79) FAB subtype L1 135 10 (9.09) 100 (90.91) L2 98 5 (6.33) 74 (93.67) Age (Y) <1 6 0 (0.00) 5 (100) 1–10 147 11 (7.24) 141 (92.76) >10 83 8 (13.56) 51 (86.44) ALL: acute lymphoblastic leukaemia, F: female, M: male, Y: year. ‡P ≤ .05 (statistically signiﬁcant). P value .92 .31 .67 .27 CD10− 9 (64.29) 28 (84.85) 11 (73.33) 26 (81.25) 19 (76.00) 15 (78.95) 0 (0.00) 20 (90.91) 17 (70.83) T-cell ALL (n = 47) CD10+ 5 (35.71) 5 (15.15) 4 (26.67) 6 (18.75) 6 (24.00) 4 (21.05) 1 (100) 2 (9.09) 7 (29.17) P value .24 .81 .89 .038‡