Nucleic Acids Research, 2009, Vol. 37, Database issue D843 Figure 1. An example of data integration and gene information page. (A) Functional menu on the head of each page. (B) Data browser by method or dataset. (C) Data integration page. (D) An example of data integration. (E) Detailed information of each gene identiﬁed by the data integration (partial page). Third, BLAST search against the nucleotide or protein sequences of the ethanol-related genes in each organism or all the ﬁve organisms is available in ERGR. DATA INTEGRATION One current opportunity and challenge is the increasing large amount of public data that can be applied to the study of alcohol-related traits. Given the growth and scale of these data, eﬃcient integration is necessary in studying a complex disorder such as alcohol dependence. Currently, ERGR provides the users data union and inter- section functions for data integration; however, more functions are being developed in this ongoing project. Moreover, ERGR provides candidate gene selection results based on the evidence in multiple datasets and multiple organisms.