C° ešková et al grandiosity, P7 hostility, G1 somatic concern, G2 anxiety, G3 guilt feelings, G4 tension, G6 depression, G7 motor retardation). Conversely, at discharge the nonresponders had significantly higher scores of individual symptoms with the exception of P4 excitement, P5 grandiosity, P7 hostility, G3 guilt feelings, G5 mannerisms and posturing, and G14 poor impulse control; ie, the significantly higher psychopathology was observed in 25 out of 30 items (see Table 2). Association between positive and negative symptoms Delusions and hallucinations did not correlate significantly with negative symptoms. A significant positive correlation Table 2 Comparison of symptoms in responders and nonresponders (mean values) was found between conceptual disorganization and emotional and social withdrawal, poor rapport, difficulty in abstract thinking, and lack of spontaneity and stereotyped thinking. Significant negative correlation was found between excitement and blunted affect, and emotional and social withdrawal; and significant positive correlation was found between excitement, difficulty in abstract thinking, and stereotyped thinking. Significant negative correlation was observed between grandiosity and blunted affect and lack of spontaneity; and positive correlation was observed between grandiosity and difficulty in abstract thinking. Suspiciousness and hostility correlated significantly with difficulty in abstract and stereotyped thinking, and hostility correlated significantly with poor rapport (see Table 3). Responder mean SD Admission Nonresponder mean SD p-values Responder mean SD Discharge Nonresponder mean SD p-values NOTE: symptom presence–score minimally 4 for individual items; NS – significant level > 0.1. Abbreviations: Resp responders; nonresp, nonresponders; PANSS, Positive and Negative Syndrome Scale. 182 Neuropsychiatric Disease and Treatment 2005:1(2) Measure n P1 delusions P2 conceptual disorganization P3 hallucinatory behavior P4 excitement P5 grandiosity P6 suspiciousness/persecutions P7 hostility Positive subscale PANSS N1 blunted affect N2 emotional withdrawal N3 poor rapport N4 passive/apathetic social withdrawal N5 difficulty in abstract thinking N6 lack of spontaneity and flow of conversation N7 stereotyped thinking Negative Subscale PANSS G1 somatic concern G2 anxiety G3 guilt feelings G4 tension G5 mannerisms and posturing G6 depression G7 motor retardation G8 uncooperativeness G9 unusual thought content G10 disorientation G11 poor attention G12 lack of judgment and insight G13 disturbance of volition G14 poor impulse control G15 preoccupation G16 active social avoidance General subscale PANSS Total Score PANSS 76 4.8 4.3 3.7 2.7 2.0 4.5 1.9 24.0 3.5 4.0 4.0 4.0 4.7 3.8 4.1 28.1 2.8 2.9 1.9 2.9 2.5 2.4 2.6 3.0 3.8 2.2 4.5 5.1 4.0 2.1 4.1 4.0 51.0 103.1 1.8 1.4 1.8 1.7 1.5 1.2 1.4 6.6 1.6 1.6 1.7 1.6 1.8 1.8 1.5 9.1 2.0 1.6 1.4 1.5 1.4 1.5 1.6 2.0 1.3 1.5 1.2 1.3 1.2 1.4 1.4 1.5 11 22 28 4.0 2.9 3.0 1.8 1.5 3.9 1.5 18.6 2.6 3.2 2.6 3.2 3.0 2.7 3.3 20.6 2.1 2.8 1.8 2.5 1.7 2.5 2.8 1.7 2.9 1.3 3.4 4.2 3.2 1.4 3.0 3.0 40.4 79.7 1.4 1.2 1.7 1.0 1.0 1.0 0.7 3.4 1.1 0.8 0.8 1.1 1.4 1.1 0.9 4.8 1.0 1.1 1.2 1.1 1.0 1.4 1.1 0.9 1.0 1.1 0.7 1.0 1.1 0.7 1.0 0.9 7.6 12.6 0.0445 < 0.001 NS 0. 0186 NS 0.0223 NS < 0.001 0.005 0.0223 < 0.001 0.0160 < 0.001 0.0036 0.0135 < 0.001 NS NS NS NS 0.0112 NS NS 0.0014 0.0019 0.0045 < 0.001 0.0037 0.0042 0.0145 < 0.001 0.0016 < 0.001 < 0.001 76 1.5 1.6 1.1 1.1 1.2 1.9 1.0 9.4 2.3 2.4 2.1 2.2 2.2 2.0 2.1 15.6 1.5 1.3 1.4 1.3 1.5 1.6 2.0 1.1 1.7 1.0 2.5 3.3 2.3 1.1 2.1 2.0 27.8 52.7 0.8 0.8 0.3 0.5 0.6 0.8 0.3 2.5 1.0 1.0 1.0 1.0 1.2 1.0 0.9 5.5 0.9 0.7 0.8 0.6 0.9 0.9 1.0 0.4 0.8 0.0 0.8 1.0 0.9 0.4 0.9 0.8 6.6 12 28 2.1 2.4 1.6 1.4 1.5 2.6 1.2 12.7 3.2 3.3 3.2 3.2 2.9 2.8 3.2 21.8 2.0 1.7 1.6 1.7 1.9 2.2 2.7 1.5 2.2 1.2 3.0 3.8 3.1 1.2 3.0 2.8 35.9 70.6 1.0 1.1 0.9 0.8 1.0 0.9 0.4 3.9 0.8 0.6 1.0 0.9 1.0 1.2 0.7 4.5 1.0 1.0 1.2 0.9 1.0 1.1 0.9 0.8 0.8 0.5 0.7 0.8 1.1 0.6 0.8 0.8 8.2 14.2 0.0026 < 0.001 < 0.001 NS NS < 0.001 NS < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 0.0059 0.0022 < 0.001 < 0.001 0.0228 0.0163 NS 0.0068 NS 0.0061 < 0.001 0.0052 0.0059 0.0050 0.0020 0.0078 < 0.001 NS < 0.001 < 0.001 < 0.001 < 0.001