Pediatr Nephrol (2008) 23:541–551 b. Insulin-dependent diabetes early in the early gesta- tional period c. Insulin dependency later in the pregnancy d. Exposure to progestational agents later in the pregnancy e. None of the above 8. Which of the following statements is most true about sacral agenesis? a. Motor function in the lower extremities and sacral area are normal b. Motor function in the lower extremities and sacral area are impaired c. The abnormality can be diagnosed in the newborn period due to an abnormal gluteal cleft d. Sensation in the lower extremities and sacral area are normal e. Sensation in the lower extremities and sacral area are impaired 9. Most children with cerebral palsy have what type of lower urinary tract function on urodynamics testing? a. b. c. d. e. A hyperactive bladder with denervation in the external urethral sphincter A hyperactive bladder with bladder sphincter dyssynergy during voiding An underactive bladder with denervation in the external urethral sphincter An underactive bladder with a normally innervated external urethral sphincter A normally reflexic bladder with bladder sphincter synergy during voiding 10. The most common cause of a traumatic spinal cord injury in babies is a. A motor vehicle accident involving a child who is not wearing a seat belt b. An inadvertent fall from a high place c. A hyperextension injury to the cervical spine during delivery d. Spinal column surgery to correct either an intra- spinal process or scoliosis e. A sports related injury References 1. Palomaki GE, Williams JR, Haddow JE (1999) Prenatal screening for open neural-tube defects in Maine. N Engl J Med 340:1049– 1050 2. Centers for Disease Control and Prevention (2004) Spina bifida and anencephaly before and after folic acid mandate—United 549 States, 1995–1996 and 1999–2000. MMWR Morb Mortal Wkly Rep 53:362–365 3. Williams LJ, Rasmussen SA, Flores A, Kirby RS, Edmonds LD (2005) Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995–2002. Pediatrics 116:580–586 4. Rothenberg SP, da Costa MP, Sequeira JM, Cracco J, Roberts JL, Weedon J, Quadros EV (2004) Autoantibodies against folate receptors in women with a pregnancy complicated by a neural- tube defect. N Engl J Med 350:134 5. Neveus T, von Gontard A, Hoebeke P, Hjalmas K, Bauer S, Bower W, Jorgensen TM, Rittig S, Vande Walle J, Yeung CK, Djurhuus JC (2006) The standardization of terminology of lower urinary tract function in children and adolescents: report from the standardization committee of the International Children’s Conti- nence Society. J Urol 176:314–324 6. Bauer SB, Labib KB, Dieppa RA, Retik AB (1977) Urodynamic evaluation in a boy with myelodysplasia and incontinence. Urology 10:354–362 7. Gierup J, Ericsson NO (1970) Micturition studies in infants and children: intravesical pressure, urinary flow and urethral resistance in boys with intravesical obstruction. Scand J Urol Nephrol 4:217–230 8. Blaivas JG, Labib KB, Bauer SB, Retik AB (1977) Changing concepts in the urodynamic evaluation of children. J Urol 117:778–781 9. Bauer SB (2003) Urodynamics in Myelodysplasia. Bladder and Bowel Dysfunction in Myelodysplasia Symposium, 3 April 2003, Aachen, Germany 10. McGuire EJ, Wang CC, Usitalo H, Savastano J (1986) Modified pubovaginal sling in girls with myelodysplasia. J Urol 135:94–96 11. Bauer SB, Hallet M, Khoshbin S, Lebowitz RL, Winston KR, Gibson S, Colodny AH, Retik AB (1984) The predictive value of urodynamic evaluation in the newborn with myelodysplasia. JAMA 152:650–652 12. Sidi AA, Dykstra DD, Gonzalez R (1986) The value of urodynamic testing in the management of neonates with myelo- dysplasia: a prospective study. J Urol 135:90–93 13. Perez LM, Khoury J, Webster GD (1992) The value of urodynamic studies in infants less than one year old with congenital spinal dysraphism. J Urol 148:584–587 14. Bauer SB (1984) Vesico-ureteral reflux in children with neuro- genic bladder dysfunction. In: Johnston JH (ed) International perspectives in urology, vol 10. Williams & Wilkins, Baltimore, pp 159–177 15. Seki N, Akazawa K, Senoh K, Kubo S, Tsunoda T, Kimoto Y, Naito S (1999) An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia. Br J Urol 84:679–682 16. Hopps CV, Kropp KA (2003) Preservation of renal function in children with myelomeningocele managed with basic newborn evaluation and close followup. J Urol 169:305–308 17. Teichman JMH, Scherz HC, Kim KD, Cho DH, Packer MG, Kaplan GW (1994) An alternative approach to myelodysplasia management: aggressive observation and prompt intervention. J Urol 152:807–811 18. Geranoitis E, Koff SA, Enrile B (1988) Prophylactic use of clean intermittent catheterization in treatment of infants and young children with myelomeningocele and neurogenic bladder dysfunc- tion. J Urol 139:85–86 19. Edelstein RA, Bauer SB, Kelly MD, Darbey MM, Peters CA, Atala A, Mandell J, Colodny AH, Retik AB (1995) The long-term urologic response of neonates with myelodysplasia treated proactively with intermittent catheterization and anticholinergic therapy. J Urol 154:1500–1504 20. Wu H-Y, Baskin LS, Kogan BA (1997) Neurogenic bladder dysfunction due to myelomeningocele: Neonatal versus childhood treatment. J Urol 157:2295–2297