Nucleic Acids Research, 2007, Vol. 35, No. 22 7585 Table 5. Substrates known to be transported by E. coli (2-Aminoethyl)phosphonate Curlin, major subunit 1,6-AnhMurNAc 2-Dehydro-3-deoxy-D-gluconate 2-O-Alpha-mannosyl-D-glycerate 3-(3-Hydroxyphenyl)propionate 3-Aminopropylphosphonate 3-Phospho-serine 4-Aminobutyrate A C4-dicarboxylate A carbohydrate A dipeptide A drug A fatty acid A glucoronide A lipopolysaccharide A macrolide antibiotic A nucleoside A peptide A peptide antibiotic A quaternary amine Acetate Adenosine Agmatine Alpha-ketoglutarate Alpha-L-arabinose Aminomethylphosphonate Ammonia An alkylphosphonate Arbutin Arsenate Beta-alanine Beta-D-galactose Beta-D-glucose Beta-D-glucose-6-phosphate Ca2+ Cadaverine Cd2+ Cellobiose Chitobiose Chloride Choline Citrate Co2+ Cob(I)alamin Cu+ Cu2+ Cyanate Cytidine Cytosine D-alanine D-allose D-cycloserine D-galactarate D-galactonate D-glucarate D-methionine D-ribose D-serine D-sorbitol D-xylose Deoxyadenosine Deoxycytidine Deoxyinosine Deoxyuridine Enterobactin Ethylphosphonate Fe2+ Ferric coprogen Ferric dicitrate Ferric dihydroxybenzoylserine Ferric enterobactin Folded proteins Formate Fosmidomycin Fructose Fructuronate Fumarate Galactitol Galacturonate Gamma-butyrobetaine GlcNAc-1,6-anhydro-MurNAc- L-Ala-gamma-D- Glu-meso-diaminopimelic acid-D-Ala Gluconate Glucosamine Glucuronate Glutathione Glycerol Glycine Glycine betaine Glycolate Glyoxylate Guanosine H+ H2O Homoserine Homoserine lactone Hydrophilic solute or ion <600 Da Indole Inosine Iron (III) hydroxamate complex Isethionate K+ L-alanine L-arginine L-ascorbate L-asparagine L-aspartate L-carnitine L-cysteine L-fucose L-glutamate L-glutamine L-histidine L-idonate L-isoleucine L-lactate L-leucine L-lysine L-methionine L-ornithine L-phenylalanine L-proline L-rhamnose L-serine L-threonine L-tryptophan L-tyrosine L-valine Lactose Li+ Malate Maltose Mannitol Mannose Melibiose Methylphosphonate Mg2+ Mn2+ Mono-, di-, or trisaccharide <600 Da MoO42 Multidrug N-acetyl-D-glucosamine N-acetylmuramate N-acetylneuraminate Na+ NH4+ Ni2+ Nicotinamide Mononucleotide Nitrite Non-speciﬁc ion/solute O-acetyl-L-serine O-antigen Orotate Pantothenate Phenylphosphonate Phosphate Phosphite Propylphosphonate Protoheme IX Putrescine Pyridoxal Pyridoxamine Pyridoxine Salicin Shikimate Sn-glycerol-3-phosphate Spermidine Succinate Sulfate Tartrate Taurine Thiamin Thiosulfate Thymidine Trehalose Uracil Uridine Xanthine Xanthosine Zn2+ right (horizontal arrows), by smaller or larger degrees (single arrows versus double arrows). New views can also be selected by entering a gene name in the entry ﬁeld near the top and clicking Go, or by entering start and stop base pairs and clicking Go. This genome browser has several novel aspects including the multiline presentation, and the clear visual designation of diﬀerent gene types, of operons, and of promoters and terminators. Genes within the same operon are displayed in the same colour; operon boundaries are also indicated by the gray or green backgrounds behind genes. The green back- ground denotes operons with experimental evidence; gray denotes computationally predicted operons. Transcription start sites and terminators are displayed at high magni- ﬁcations. Protein-coding genes are displayed with isosceles arrowheads (such as ydiL in the second row), and RNA-coding genes are displayed with slanting heads (such as rprA in the second row). Pseudogenes contain a large X (see next to last row). (EcoCyc deﬁnes pseudo- genes both as genes that are cryptic (not expressed), and as genes that are not able to encode a functional protein product.) Moving the mouse pointer over a given gene will display information about it in a pop-up window or at the bottom of the screen. For clarity, genes with signiﬁcant overlaps are positioned above one another. The Show Tracks button in the upper right allows display tracks to be created to display regions along the genome that are deﬁned in a GFF ﬁle, as supported by other genome browsers such as Gbrowse (23) and the