Nucleic Acids Research, 2006, Vol. 34, Web Server issue W229 Figure 3. Target page showing a target list. The selected targets are ranked according to the order and priority specified for the different annotations, and a table of prioritized targets is built using the annotations that were chosen for display. In this case, a list of 49 targets (selected from M.genitalium’s genome with the criteria specified in Figure 1) was ranked by decreasing coverage by NRDB database proteins, and a table constructed showing the target’s identifier (in sgTarget), accession number, name, molecular weight, length, GRAVY score, isoelectric point, coverage by NRDB database proteins (including the span of the alignments on the target and the top taxonomic group which encompasses all reported alignments) and function annotation (the top InterPro hit and its GO high-level molecular function) (as specified in Figure 2). Figure 4. P.falciparum annotation wheel, with an emphasis on structural annotation. Annotations are displayed anti-clockwise as follows: A total of 1055 proteins have structural annotations, 691 high-confidence and 364 low-confidence (PDB SEQRES, release 05/2002); Of the remaining proteins, 3714 are likely to be intractable: 1475 have transmembrane regions, a further 2131 have disordered regions and the other 108 have fibrous regions; For the remainder of the proteome, 187 proteins have function annotations, although only 97 of these are classified by GO; Most other proteins are found in other organisms (295), except for 16 ORFan proteins.