Nucleic Acids Research, 2012, Vol. 40, Database issue D59 Figure 2. Screenshot of a Genome Sequencing project that is a component of an umbrella project that encompasses data generated from an E. coli pathogen outbreak (upper panel) (17) and a corresponding sample record (lower panel). The records display the project title, summary, data type, locus_tag preﬁx and various project attributes including the scope and capture method (A). The Project Data section (B) lists the availability of corresponding sequence and assembly data in the Nucleotide and SRA databases where the data can be downloaded. Navigation panels assist users to link to Genome-level resources for that organism (C), or to ‘Navigate Up’ to the parent umbrella project, or to ‘Navigate across’ to sibling projects that are part of that umbrella project, as well as any additional projects related by organism (D). The ‘Related Information’ panel (E) contains full list of linkages for that record; clicking the BioSample link directs the user to the sample record shown in the lower panel, which lists the attributes that were collected for that sample including the collection date, isolation source, country and strain and serovar (F). perspective (Figures 1 and 2). This organization supports the ability to collect and organize metadata at both the level of the subproject and the larger collaboration while grouping them together to ﬂexibly support access to the project information and submitted archival data. In addition, projects can be cross-linked to represent other types of relationships between data sets such as reuse of a predeﬁned reference genome standard by an independ- ent research initiative, or biologically relevant rela- tionships or dependencies at the organismal level such as host–parasite. Examples of BioProjects include: (i) PRJNA59457, a metagenome project investigating