imperative that signiﬁcant populations at risk and important trends be identiﬁed. Such iden- tiﬁcation will help health care clinicians apply recommendations from the scientiﬁc literature to the patients they see in their communities, where appropriate. Conclusion Study subjects in NHANES who self-identi- f i e d a s A s i a n , P a c i f i c I s l a n d e r , N a t i v e American, or multiracial had a higher preva- lence of elevated blood mercury than all other racial/ethnic participants in the survey. It is important that both patients and clinicians be aware that members of this group are at increased risk for methylmercury exposure. Future studies should address reasons for the high mercury levels in this group and explore possible interventions for lowering risk of methylmercury exposure in this population. CORRECTION The standard error of 0.4% that appeared in the text and Table 1 of the original manu- script published online was incorrect. It has been corrected here to 4.0. REFERENCES AMA. 2004. Report 13 of the Council on Scientiﬁc Affairs (A-04) Mercury and Fish: Consumption: Medical and Public Health Issues 2004. Chicago, IL:American Medical Association. Available: http://www.ama-assn.org/ama/pub/category/ 13619.html [accessed 27 February 2005]. Bagenstose LM, Salgame P, Monesteir M. 1999. Murine mer- cury-induced autoimmunity: a model of chemically related autoimmunity in humans. Immunol Res 20(1):67–78. Bernier J, Brousseau P, Krystyniak K, Tryphonas H, Fournier M. 1995. Immunotoxicity of heavy metals in relation to Great Lakes. Environ Health Perspect 103(suppl 9):23–34. Beuter A, Edwards R. 2004. Effect of chronic exposure to methylmercury on eye movements in Cree subjects. Int Arch Occup Environ Health 77(2):97–107. Bigazzi PE. 1994. Autoimmunity and heavy metals. Lupus 3(6):449–453. Bjerregaard P, Hansen JC. 2000. Organochlorines and heavy metals in pregnant women from the Disco Bay area in Greenland. Sci Total Environ 245:195–202. CDC (Centers for Disease Control and Prevention). 2004. Blood mercury levels in young children and childbearing-aged women—United States, 1999–2002. MMWR Morb Mortal Wkly Rep 53(43):1018–1020. CDC. 2005. Public Use Data Files. Analytical Guidelines. Atlanta, GA:Centers for Disease Control and Prevention, National Center for Health Statistics. Available: http://www.cdc.gov/ nchs/about/major/nhanes/datalink.htm [accessed 6 May 2005]. Choy CM, Lam CW, Cheung LT, Briton-Jones CM, Cheung LP, Haines CJ. 2002. Infertility, blood mercury concentrations and dietary seafood consumption: a case-control study. Br J Obstet Gynaecol 109(10):1121–1125. Clarkson TW. 1976. Exposure to methylmercury in Grassy Narrows and White Dog Reserves: An Interim Report. Ottawa, Ontario, Canada:Ottawa Health and Welfare Canada. Dickman MD, Leung KMC. 1998. Mercury and organochlorine exposure from fish consumption in Hong Kong. Chemosphere 37(5):991–1015. Dye BA, Schober SE, Dillon CF, Jones RL, Fryar C, McDowell M, et al. 2005. Urinary mercury concentrations associated with dental restorations in adult women aged 16–49 years: United States, 1999–2000. Occup Environ Med 62:368–375. Frustaci A, Magnavita N, Chimenti C, Caldarulo M, Sabbioni E, Pietra R, et al. 1999. Marked elevation of myocardial trace elements in idiopathic dilated cardiomyopathy compared with secondary cardiac dysfunction. J Am Coll Cardiol 33(6):1578–1583. Fukuda Y, Ushijima K, Kitano T, Sakamoto M, Futatsuka M. 1999. An analysis of subjective complaints in a population living in a methylmercury-polluted area. Environ Res A 81:100–107. Girard M, Noel F, Dumont C. 1996. Varying mercury exposure with varying food source in James Bay Cree community. Arctic Med Res 55(2):69–74. Guallar E, Sanz-Gallardo I, Van’t Veer P, Bode P, Aro A, Gomez- Aracena J, et al. 2002. Mercury, fish oils, and the risk of myocardial infarction. N Eng J Med 347(22):1747–1754. Harnly M, Seidel S, Rojas P, Fornes R, Flessel P, Smith D, et al. 1997. Biological monitoring for mercury within a com- munity with soil and fish contamination. Environ Health Perspect 105:424–429. Hightower JM, Moore D. 2003. Mercury levels in high-end con- sumers of ﬁsh. Environ Health Perspect 111:604–608. Knobeloch L, Anderson HA, Imm P, Peters D, Smith A. 2005. Fish consumption, advisory awareness, and hair mercury levels among women of childbearing age. Environ Res 97(2):219–226. Leung TY, Choy CM, Yim SF, Lam CW, Haines CJ. 2001. Whole blood mercury concentrations in sub-fertile men in Hong Kong. Aust N Z J Obstet Gynaecol 41(1):75–77. Mahaffey KR. 2005. Mercury Exposure: Medical and Public Health Issues. Trans Am Clin Climatol Assoc 116:127–154. Mahaffey KR, Clickner RP, Bodurow CC. 2004. Blood organic mercury and dietary mercury intake: National Health and Nutrition Examination Survey, 1999 and 2000. Environ Health Perspect 112:562–570. Marsh DO, Turner MD, Crispin Smith J, Wun Choi J, Clarkson TW. 1974. Methylmercury (MeHg) in human population eating large quantities of marine ﬁsh. II. American Samoa: cannery workers and fishermen. In: Proceedings of the First International Mercury Conference, May 1974, Barcelona. Vol 2. Madrid:Fabrica de Moneda y Timbre, 235–239. McKeown-Eyssen GE, Ruedy J, Neims A. 1983. Methylmercury exposure in northern Quebec. II. Neurologic findings in children. Am J Epidemiol 118(4):470–479. Mergler D, Belanger S, Larribe F, Panisset M, Bowler R, Baldwin M, et al. 1998. Preliminary evidence of neurotoxi- city associated with eating fish from the Upper St. Lawrence River Lakes. Neurotoxicology 19(4–5):691–702. Muckle G, Ayotte P, Dewailly É, Jacobson S, Jacobson J. 2001. Prenatal exposure of the northern Québec Inuit infants to environmental contaminants. Environ Health Perspect 109:1291–1299. National Center for Health Statistics. 2005. NHANES 1999–2000 and NHANES 2001–2002 Public Use Data Files. Hyattsville, MD:National Center for Health Statistics. Available: http:// www.cdc.gov/nchs/about/major/nhanes/nhanes01-02.htm [accessed 27 February 2005]. Nielsen JB, Hultman P. 2002. Mercury induced autoimmunity in mice. Environ Health Perspect 110(suppl 5):877–881. Rice DC. 2004. The US EPA reference dose for methylmercury: sources of uncertainty. Environ Res 95:406–413. Rice DC, Schoeny R, Mahaffey KR. 2003. Methods and rationale for derivation of a reference dose for methylmercury by U.S. EPA. Risk Anal 23:107–115. Blood mercury reporting in NHANES Rissanen T, Voutilainen S, Nyyssönen K, Lakka TA, Salonen JT. 2000. Fish oil-derived fatty acids, docosahexaenoic acid and docosapentanoic acid, and the risk of acute coronary events. Circulation 102:2677–2679. Salonen JT, Seppänen K, Lakka TA, Salonen R, Kaplan GA. 2000. Mercury accumulation and accelerated progression of carotid atherosclerosis: a population-based prospec- tive 4-year follow-up study in men in Eastern Finland. Atherosclerosis 148:265–273. Salonen JT, Seppänen K, Nyyssönen K, Korpela H, Kauhanen J, Kantola M, et al. 1995. Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation 91(3):645–655. Sechena R, Liao S, Lorenzana R, Nakano C, Polissar N, Fenske R. 2003. Asian American and Paciﬁc Islander seafood con- sumption-a community-based study in King County, Washington. J Expo Anal Environ Epidemiol 13(4):256–266. Sheiner EK, Sheiner E, Hammel RD, Potashnik G, Carel R. 2003. Effect of occupational exposures on male fertility: litera- ture review. Ind Health 41(2):55–62. Silva IA, Nyland JF, Gorman A, Perisse A, Ventura AM, Santos EC, et al. 2004. Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon popula- tions in Brazil: a cross sectional study. Environ Health 3(1):11. Available: http://www.ehjournal.net/content/pdf/ 1476-069X-3-11.pdf [accessed 19 December 2005]. Sørensen N, Murata K, Budtz-Jørgensen E, Weihe P, Grandjean P. 1999. Prenatal methylmercury exposure as a cardio- vascular risk factor at seven years of age. Epidemiology 10:370–375. Stejskal J, Stejskal VDM. 1999. The role of metals in autoimmu- nity and the link to neuroendocrinology. Neuro Endocrinol Lett 20:351–364. Stejskal VDM, Danersund A, Lindvall A, Hudecek R, Nordman V, Yaqob A, et al. 1999. Metal-speciﬁc lymphocytes: biomarkers of sensitivity in man. Neuro Endocrinol Lett 20(5):289–298. Stern AH, Smith AE. 2003. An assessment of the cord blood: maternal blood methylmercury ratio: implications for risk assessment. Environ Health Perspect 111:1465–1470. U.S. Census Bureau. 2002a. The American Indian and Alaskan Native Population: 2000. Washington, DC:U.S. Census Bureau. Available: http://www.census.gov/prod/2002pubs/ c2kbr01-15.pdf [accessed 14 May 2005]. U.S. Census Bureau. 2002b. The Asian and Pacific Islander Population in the United States. Washington, DC:U.S. Census Bureau. Available: http://www.census.gov/prod/2003pubs/ p20-540.pdf [accessed 14 May 2005]. Ventura SJ, Hamilton BE, Sutton PD. 2003. Revised Birth and Fertility Rates for the United States, 2000 and 2001. National Vital Statistics Reports 51(4). Atlanta, GA:Centers for Disease Control and Prevention. Available: http://www.cdc.gov/ nchs/data/nvsr/nvsr51/nvsr51_04.pdf [accessed 12 January 2005]. Via CS, Nguyen P, Niculescu F, Papadimitriou J, Hoover D, Silbergeld E. 2003. Low dose exposure to inorganic mer- cury accelerates disease and mortality in acquired murine lupus. Environ Health Perspect 111:1273–1277. Virtanen JK, Voutilainen S, Rissanen TH, Mursa J, Tuomainen TP, Korhonen MJ, et al. 2005. Mercury, ﬁsh oils, and risk of acute coronary events and cardiovascular disease, coro- nary heart disease, and all-cause mortality in men in east- ern Finland. Arterioscler Thromb Vasc Biol 25(1):228–233. Weihe P, Hansen JC, Murata K, Debes F, Jorgensen P, Steuerwald U, et al. 2002. Neurobehavioral performance of Inuit children with increased prenatal exposure to methyl- mercury. Int J Circumpolar Health 61(1):41–49. Yokoo EM, Valente JG, Grattan L, Schmidt SL, Platt I, Silbergeld EK. 2003. Low level methylmercury exposure affects neu- ropsychological functioning in adults. Environ Health 2:8. Available: http://www.ehjournal.net/content/pdf/1476-069- 2-8.pdf [accessed 19 December 2005]. Environmental Health Perspectives • VOLUME 114 | NUMBER 2 | February 2006 175