1802 water diffusion by means of magnetic resonance imaging. Magn Reson Med 53:1432–1440 15. Wu EX, Cheung MM (2010) MR diffusion kurtosis imaging for neural tissue characterization. NMR Biomed 23:836–848 16. Farrell JA, Zhang J, Jones MV et al (2010) q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy. Magn Reson Med 63:1323–1335 17. Raab P, Hattingen E, Franz K, Zanella FE, Lanfermann H (2010) Cerebral gliomas: diffusional kurtosis imaging analysis of micro- structural differences. Radiology 254:876–881 18. Jansen JF, Stambuk HE, Koutcher JA, Shukla-Dave A (2010) Non-Gaussian analysis of diffusion-weighted MR imaging in head and neck squamous cell carcinoma: a feasibility study. AJNR Am J Neuroradiol 31:741–748 19. Jensen JH, Falangola MF, Hu C et al (2010) Preliminary observa- tions of increased diffusional kurtosis in human brain following recent cerebral infarction. NMR Biomed 24:452–457 20. Helpern JA, Adisetiyo V, Falangola MF et al (2011) Preliminary evidence of altered gray and white matter microstructural devel- opment in the frontal lobe of adolescents with attention-deficit hyperactivity disorder: a diffusional kurtosis imaging study. J Magn Reson Imaging 33:17–23 21. Clark CA, Le Bihan D (2000) Water diffusion compartmentation and anisotropy at high b values in the human brain. Magn Reson Med 44:852–859 Eur Radiol (2012) 22:1797–1802 22. Lu H, Jensen JH, Ramani A, Helpern JA (2006) Three-dimensional characterization of non-Gaussian water diffusion in humans using diffusion kurtosis imaging. NMR Biomed 19:236–247 23. Song T, Chen WJ, Yang B et al (2011) Diffusion tensor imaging in the cervical spinal cord. Eur Spine J 20:422–428 24. Ries M, Jones RA, Dousset V, Moonen CT (2000) Diffusion tensor MRI of the spinal cord. Magn Reson Med 44:884–892 25. Inano S, Takao H, Hayashi N, Abe O, Ohtomo K (2011) Effects of age and gender on white matter integrity. AJNR Am J Neuroradiol 32:2103–2109 26. Facon D, Ozanne A, Fillard P, Lepeintre JF, Tournoux-Facon C, Ducreux D (2005) MR diffusion tensor imaging and fiber tracking in spinal cord compression. AJNR Am J Neuroradiol 26:1587– 1594 27. al-Mefty O, Harkey HL, Marawi I et al (1993) Experimental chronic compressive cervical myelopathy. J Neurosurg 79:550– 561 28. Graham DI, Lantos PL (2002) Greenfield’s neuropathology, 7th edn. Oxford University Press, New York 29. Cheung MM, Hui ES, Chan KC, Helpern JA, Qi L, Wu EX (2009) Does diffusion kurtosis imaging lead to better neural tissue char- acterization? A rodent brain maturation study. Neuroimage 45:386–392 30. Lätt J, Nilsson M, Wirestam R et al (2008) In vivo visualization of displacement-distribution-derived parameters in q-space imaging. Magn Reson Imaging 26:77–87