Case Reports in Obstetrics and Gynecology early, to decrease the morbidity and mortality. Speciﬁed dosages and protocols should be used for limited time and alternative methods employed if it fails. Chances of recurrence of rupture in next pregnancy will be high that is, 4%–19%. So, either tubal ligation should be done or advice elective caesarean section in next pregnancy [11]. 4. Conclusion In the present days, there is a gradual increase in second trimester pregnancy termination, due to prenatal screening for diagnosis of severe fetal cardiovascular and skeletal malformations and also due to social reasons. Misoprostol which is the commonly used method for second trimester termination of pregnancy should be used cautiously, as life-threatening complications are associated with this. If it fails, alternative methods should be used. Patient should be counseled about the complications, and obstetricians should be aware about the uncommon but inevitable complications like uterine rupture, postabortal bleeding needing hystero- tomy and blood transfusions. Also the second trimester terminations of pregnancy should be done in a place where facilities for dealing with the above complications are available. References [1] M. Behrashi and M. Mahdian, “Vaginal versus oral misopros- tol for second-trimester pregnancy termination: a randomized trial,” Pakistan Journal of Biological Sciences, vol. 11, no. 21, pp. 2505–2508, 2008. [2] V. Goyal, “Uterine rupture in second-trimester misoprostol- induced abortion after cesarean delivery: a systematic review,” Obstetrics and Gynecology, vol. 113, no. 5, pp. 1117–1123, 2009. [3] S. A. Tayade, S. Samal, and A. T. Tayade, “Prostaglandin ana- logues and Ethacridine lactate for 1st and 2nd trimester induced abortion,” International Journal of Biological and Medical Research, vol. 2, no. 4, pp. 1075–1077, 2011. [4] S. Syed, H. Noreen, L. E. Kahloon, and R. Chaudhri, “Uterine rupture associated with the use of intra-vaginal misoprostol during second-trimester pregnancy termination,” Journal of the Pakistan Medical Association, vol. 61, no. 4, pp. 399–401, 2011. [5] V. Berghella, J. Airoldi, A. O’Neill, K. Einhorn, and M. Hoﬀman, “Misoprostol for second trimester pregnancy termi- nation in women with prior caesarean: a systematic review,” An International Journal of Obstetrics and Gynaecology, vol. 116, no. 9, pp. 1151–1157, 2009. [6] A. Beheram, G. Sanjay, S. Nozer, and T. Jaydeep, “Consensus statement for medical termination of pregnancy,” 2004, http:// icogonline.org.blue.mysitehosted.com/innerpage/images/pdf /gcpguidelines/Medical Termination of Pregnancy.pdf. [7] “Misoprostol in obstetrics & gynecology—2nd trimester induced abortion,” 2009, http://www.misoprostol.org/File/ Guide2triabn.php. [8] W. J. LeMaire, C. Louisy, K. Dalessandri, and F. Muschenheim, “Placenta percreta with spontaneous rupture of an unscarred uterus in the second trimester,” Obstetrics and Gynecology, vol. 98, no. 5, pp. 927–929, 2001. 3 [9] R. L. Herting and C. H. Nissen, “Overview of misoprostol clinical experience,” Digestive Diseases and Sciences, vol. 31, no. 2, pp. 475–545, 1986. [10] S. J. Chapman, M. Crispens, J. Owen, and K. Savage, “Com- plications of midtrimester pregnancy termination: the eﬀect of prior cesarean delivery,” American Journal of Obstetrics and Gynecology, vol. 175, no. 4 I, pp. 889–892, 1996. [11] Y. Herabutya and P. O-Prasertsawat, “Misoprostol in the management of missed abortion,” International Journal of Gynecology and Obstetrics, vol. 56, no. 3, pp. 263–266, 1997.