Maceﬁeld Modeling human postganglionic neuronal ﬁring FIGURE 1 | Model spike trains from two (A) or three (B) “preganglionic neurons” that converged onto a model “postganglionic neuron.” The lower trace shows the emulated nerve recording. The mean interspike interval was 2500 ± 5000 ms (SD). FIGURE 2 | (A–E) Spike interval distributions for a model postganglionic neuron generating 0–4 spikes per “cardiac interval” (1 s), while being driven by 1–3 model preganglionic neurons discharging at a mean interspike interval of 1000 ± 500 ms. (F) Spike distribution of real muscle vasoconstrictor neurons (data pooled from Maceﬁeld et al., 1994; Maceﬁeld and Wallin, 1999a). FIGURE 3 | (A–E) Spike interval distributions for a postganglionic neuron generating 0–4 spikes per “cardiac interval” (1 s), while being driven by 1–3 model preganglionic neurons discharging at a mean interspike interval of 2500 ± 5000 ms. (F) Spike distribution of real muscle vasoconstrictor neurons (data pooled from Maceﬁeld et al., 1994; Maceﬁeld and Wallin, 1999a). www.frontiersin.org December 2011 | Volume 5 | Article 132 | 3