Tension cost and contractility changes Moreira CM et al. Table 2 - Measurements of final body weight (g), left ventricular weight (mg), and the left ventricular weight/ body weight (LVW/BW) ratio (mg/g) in myocardial infarction (MI) and sham-operated (Sham) rats; spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY), diabetic; nephrectomized (Nefrec), salt-treated (salt), DOCA-treated, DOCA-Salt (DOCA), and L-NAME- treated rats. Groups Sham (23) MI (21) WKY (10) SHR (22) Control (12) Diabetic (12) Nefrec (12) Salt (12) DOCA (15) DOCA-Salt (10) Control (12) L-NAME (7) Final Body Weight (g) 347¡9.9 331¡7.9 296¡7.6 251¡7.8* 289¡4.2 262¡3.9* 285¡6.5 288¡8.7 289¡8.0 249¡7.7* 340¡7.8 319¡12.7 Left Ventricular LVW/BW ratio Weight (mg) (mg/g) 660¡20 670¡40 600¡20 700¡30* 550¡20 552¡10 540¡10 570¡20 600¡20 790¡30* 670¡20 660¡20 1.90¡0.05 2.04¡0.13 2.05¡0.04 2.82¡0.09* 1.91¡0.06 1.99¡0.03 1.89¡0.04 1.96¡0.04 2.07¡0.03 3.19¡0.16* 1.97¡0.05 2.08¡0.05 Values represent the means ¡ SEM. ANOVA one-way and t-test: *p,0.05 vs. controls of the respective groups. The number of animals is indicated in parentheses. 1.77¡0.22 0.80¡0.10* 0.87¡0.14* 0.97¡0.13* 1.79¡0.30 0.92¡0.17* 1.97¡0.14 2.08¡0.23 2.20¡0.25 1.06¡0.25* 1.71¡0.18 2.30¡0.42 Groups Sham (23) MI (21) WKY (10) SHR (22) Control (12) Diabetic (12) Nefrec (12) Salt (12) DOCA (15) DOCA-salt (10) Control (12) L-NAME (7) Values represent the means ¡ SEM. ANOVA one-way and t-test: *p,0.05 vs. controls of respective groups. The number of animals is indicated in parentheses. CLINICS 2012;67(5):489-496 Table 3 - Changes in plateau tetanic tension (g/mm2) as observed in papillary muscles obtained from myocardial infarction (MI) and sham-operated (Sham) rats; spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY), diabetic; nephrectomized (Nefrec), salt-treated (salt), DOCA-treated, DOCA-salt-treated (DOCA), and L- NAME-treated rats. Plateau Tetanic Tension (g/mm2) Figure 3 - Effects of myocardial infarction (A), hypertension (B), diabetes (C), DOCA-salt-induced hypertension (D), and chronic L-NAME treatment (E) on myosin ATPase activity (nmol/Pi/min/mg) in the rat left ventricle. The results represent the means ¡ SEM, and N indicates the number of experiments. *p,0.05 vs. control (t-test or one-way ANOVA, repeated measurements). 494