www.kjurology.org DOI:10.4111/kju.2011.52.5.335 Voiding Dysfunction Efficacy and Safety of the TVT-SECUR and Impact on Quality of Life in Women with Stress Urinary Incontinence: A 2-Year Follow-Up Ⓡ Yu Seob Shin1, Jai Seong Cha1, Min Woo Cheon3, Young Gon Kim1,2, Myung Ki Kim1,2 1Department of Urology, Chonbuk National University Medical School, 2Institute for Medical Sciences of Chonbuk National University, 3Department of Urology, Presbyterian Medical Center, Jeonju, Korea Purpose: As recently reported, the short-term results of the tension-free vaginal tape SECURⓇ (TVT-S) procedure seem to be similar to those of the conventional trans- obturator tape (TOT) procedure. However, results of efficacy and satisfaction with TVT-S are insufficient in patients with more than 1 year of follow-up. Therefore, we evaluated the results of the TVT-S procedure in women with stress urinary incon- tinence (SUI) during 2 years. Materials and Methods: We evaluated 51 patients with clinical and urodynamic diag- noses of SUI who underwent the TVT-S procedure from March 2008 to February 2009. Preoperative evaluation included a history, cough stress test with full bladder, urody- namic study, and incontinence quality of life (I-QoL) questionnaire. Following the post- operative period, urinary incontinence status was examined through a physical exami- nation and the I-QoL questionnaire was completed in an outpatient setting or by telephone. Results: Data from 2 years of follow-up were available for 46 of 51 patients. The cure rate was 80.4% at 1 month after TVT-S and 76.0% at 2 years after TVT-S. The cure or improvement rate was 93.5% at 1 month after TVT-S and 86.8% at 2 years after TVT-S. The mean total I-QoL score increased by 42 points at 1 month after TVT-S (p＜0.026) and by 32 points at 2 years after TVT-S (p＜0.013). Most patients reported significant improvements in quality of life. At the 2-year follow-up, there were no significant com- plications related to TVT-S. Conclusions: The results of this study suggest that TVT-S is an efficient and safe proce- dure for the improvement of both the quality of life of the patients and the SUI itself. Key Words: Minimally invasive surgical procedures, Treatment outcome, Urinary stress incontinence This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Article History: received 3 March, 2011 accepted 25 April, 2011 Corresponding Author: Myung Ki Kim Department of Urology, Medical School, Chonbuk National University, 634-18, Geumam-dong, Deokjin-gu, Jeonju 561-712, Korea TEL: +82-63-250-2574 FAX: +82-63-250-1564 E-mail: mkkim@jbnu.ac.kr INTRODUCTION Stress urinary incontinence (SUI) adversely affects the quality of life and well-being of approximately 15% of the female population [1]. The treatment options for SUI in- clude retropubic suspensions and slings, transobturator tape procedures, injectable bulking agents, and less com- monly, artificial urinary sphincter placement [2]. The ret- ropubic tape has been shown to be effective for many years, but exposes the patient to serious complications, such as bladder perforation, principally because of the use of the retropubic space for the fixation of the tape [3]. In an at- tempt to avoid the retropubic space, the second generation of slings, the transobturator tape, was introduced. The re- cent generation of midurethral slings, the tension-free vag- inal tape SECURⓇ (TVT-S, Gynecare, Ethicon, Somerville, Korean Journal of Urology Ⓒ The Korean Urological Association, 2011 335 Korean J Urol 2011;52:335-339