Chen et al. Journal of Experimental & Clinical Cancer Research 2010, 29:13 http://www.jeccr.com/content/29/1/13 Page 7 of 8 Author details 1Department of Dermatology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022 PR China. 2Institute of Dermatology, Guangdong Medical College, Zhanjiang, 524023, PR China. Authors’ contributions RC carried out the design of the study and molecular biological experiments; HC drafted the manuscript; JL performed the statistical analysis; PJ carried out the pathologic examination studies and western blot analysis; WS carried out the animal experiments; LX carried out the RT-PCR and immunohistochemistry; YT carried out the design of the study. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: 16 October 2009 Accepted: 16 February 2010 Published: 16 February 2010 References 1. 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