Table 1 Characteristics of Hispanic patients with eyelid pigmented basal cell carcinoma Case Sex/age Location Duration Bleeding Ulceration Madarosis Initial size Number of Defect Type of (cm) mohs stages size (cm) closure needed No Yes No Yes No Yes No Yes 0.5 × 0.4 1.2 × 1.0 4.2 × 2.0 1.0 × 0.8 1 2 2 2 0.5 x 0.7 2.2 x 2.0 5.0 x 3.0 2.5 x 2.0 Second intention Hughes Hughes Hughes 1 2 3 4 M/57 M/75 M/57 M/63 Left upper lid 2 yrs Right lower lid 7 mos Left lower lid 6 years Left medial 3 yrs canthus No Yes No Yes melanoma. Pigmented basal cell carcinoma is more likely to have mottled appearance since the pigment is often located superﬁcially in the dermis (Bigler et al 1996). Melanoma, on the other hand, tends to have intense or masking pigment (Haye and Duﬁer 1976). Other features that help differentiate PBCC from melanoma include a translucent or pearly sheen, ﬁrm or indurated lesions, areas of ulceration, and raised edges (Hornblass and Stefano 1981; Bigler et al 1996). Clinicians should be aware that PBCC of the eyelid occurs more frequently in Hispanics, a population less frequently affected by other skin carcinomas, and consider PBCC on their differential diagnosis of all pigmented eyelid lesions. Disclosure The authors received no ﬁnancial support nor do they have any proprietary or conﬂicting interests in the materials dis- cussed in this manuscript. References Abreo F, Sanusi ID. 1991. Basal cell carcinoma in North American blacks. Clinical and histopathologic study of 26 patients. J Am Acad Dermatol, 25:1005–11. Bart RS, Schnall S. 1973. Eye color in darkly pigmented basal cell carcino- mas and malignant melanomas. An aid in their clinical differentiation. Arch Dermatol, 107:206–7. Bigler C, Feldman J, Hall E, et al. 1996. Pigmented basal cell carcinoma in Hispanics. J Am Acad Dermatol, 34:751–2. Bleehan SS. 1975. Pigmented basal cell epithelioma. Light and electron microscopeicc studies on tumours and cell cultures. Br J Dermatol, 93:361–70. Charles NC. 1975. Basal cell carcinomas of the eyelids: pitfalls in diagnosis and therapy. J Dermatol Surg, 1:28–32. Duke-Elder S, MacFaul PA. 1974. Carcinoma (epithelioma). In: System of Ophthalmology. Vol 13, Part I. The Ocular Adnexa, Diseases of the Eyelids. St. Louis: CV Mosby Co., pp. 420–42. Harris RB, Grifﬁth K, Moon TE. 2001. Trends in incidence of nonmela- noma skin cancers in southeastern Arizona, 1985–1996. J Am Acad Dermatol, 45:528–36. Haye C, Duﬁer JL. 1976. Pigmented epitheliomas of the eyelids [in French]. Arch Ophtalmol (Paris), 36:633–44. Hornblass A, Stefano JA. 1981. Pigmented basal cell carcinoma of the eyelids. Am J Ophthalmol, 92:193–7. Kalter DC, Goldberg LH, Rosen T. 1984. Darkly pigmented lesions in dark- skinned patients. J Dermatol Surg Oncol, 10:876–81. Pathak DR, Samet JM, Howard CA, et al. 1982. Malignant melanoma of the skin in New Mexico 1969–1977. Cancer, 50:1440–6. Scotto J, Fears, TR, Fraumeni JF. 1983. Incidence of nonmelanoma skin cancer in the United States. NIH Publication 83-2433.Bethesda, MD: US Dept. of Health and Human Services, National Institutes of Health; NIH Publication 83-2433. Smith LM, Garrett HD, Hart MS. 1960. Pigmented basal- cell epithelioma: a comparison of its incidence and characteristics in the Latin-American and Anglo-American populations. Arch Dermatol, 81:95–102. Eyelid pigmented BCC in hispanics Follow up 2 yrs 2 yrs 1 yr 7 mos Clinical Ophthalmology 2008:2(3) 643