Morland BJ, Barley J, Boehm D, Flavell SU, Ghaleb N, Kohler JA, Okayama K, Wilkins B and Flavell DJ (1994) Effectiveness of HB2(anti-CD7)-saporin immunotoxin in an in vivo model of human T-cell leukaemia developed in severe combined immunodeficient mice. British Journal of Cancer 69: 279–285 Pilarski LM, Hipperson G, Seeberger K, Pruski E, Coupland RW and Belch AR (2000) Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice. Blood 95: 1056–1065 Prochazka M, Gaskins HR, Shultz LD and Leiter EH (1992) The non-obese diabetic scid mouse:model for spontaneous thymomagenesis associated with immunodeficiency. PNAS 89: 3290–3294 Serreze DV and Leiter EH (1988) Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies. J Immunol 140: 3801–3807 Serreze DV, Gaskins HR and Leiter EH (1993) Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. J Immunol 150: 2534–2543 Shpitz B, Fernandes BJ, Mullen JBM, Roder JC and Gallinger S (1994) Improved engraftment of human tumours in SCID mice pretreated with radiation and anti-asialo GMI. Anticancer Research 14: 1927–1934 Shultz L, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL and Leiter EH (1995) Immunotherapy in immunodeprived mice 1761 Multiple defects in innate and adaptive immunologic function in NOD/LtSz- scid mice. The Journal of Immunology 154: 180–191 Thorpe PE, Brown ANF, Jr, JAGB, Foxwell BMJ and Stirpe F (1985) An immunotoxin composed of monoclonal anti-Thy 1.1 antibody and a ribosome- inactivating protein from Saponaria officinalis: potent antitumor effects in vitro and in vivo. Journal of National Cancer Institute 75: 151–159 Wang JCY, Lapidot T, Cashman JD, Sirard C, Doedens M, Laraya P, Addy L, Minden M, Keating A, Eaves AC, Eaves CJ and Dick JE (1995) Engraftment of primitive normal and leukemic hematopoetic cells from chronic phase CML patients in immunodeficient mice. Blood 86: 601a Workman P, Twentyman P, Balkwill F, Balmain A, Chaplin D, Double J, Embleton J, Newell D, Raymond R, Stables J, Stephens T and Wallace J (1998) United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia (second edition). Br J Cancer 77: 1–10 Yu J, Dialynas DP, Shao LE, Lee MJ, Gold DP and Yu AL (1999) Fetal cord blood facilitates engraftment of primary childhood T-cell acute lymphoblastic leukaemia in immunodeficient mice and enhances leukaemia colony formation in vitro. Proc Am Assoc Cancer Res 40: 660 (abstract #4352) © 2000 Cancer Research Campaign British Journal of Cancer (2000) 83(12), 1755–1761