Health as a Program of Excellence in Nanotechnology ( HHSN- 268201000046C), and the National Science Foundation under Grant Number DMR-1032267. The Welch Foundation is grate- fully acknowledged for support through the W. T. Doherty-Welch Chair in Chemistry, Grant No. A-0001. This work was also supported by financial support from Knut and Alice Wallenberg Foundation, Karolinska Institutet, Jeanssons Foundation, Åke Wibergs Foundation, Eva and Axel Wallstro€ms Foundation, Carl Bennet AB, The Swedish Research Council ( VR) 2009-3259, The Swedish Medical Nanoscience Center and The Swedish Governmen- tal Agency for Innovation Systems ( Vinnova). BIOGRAPHICAL INFORMATION Andreas M. Nystro€m received his M.Sc. in Chemical Engineering and Polymer Technology in 2002 from the Royal Institute of Technology (KTH) in Stockholm, Sweden, after which he continued with his Ph.D. (engineering) in dendrimer chemistry under the guidance of Prof. Anders Hult at KTH. In 2006, Andreas joined Prof. Karen L. Wooley at Washington University in Saint Louis for a 2 year postdoctoral position, financed by a distinguished assistant professor and postdoctoral grant from Knut and Alice Wallenberg foundation. In 2009, Andreas joined the faculty at Karolinska Institute (KI) of Medicine as an assistant professor working with polymeric nanosystems for cancer therapy and imaging, and in 2010 joined the Swedish Medical Nanoscience Center at KI as an Associate Professor of Nanomedicine. Andreas serves as interna- tional reviewer for the Czech National Science Foundation and is a part-owner and member of the management of Polymer Factory AB, a company that is commercializing polyester based dendrimers. Karen L. Wooley holds the W. T. Doherty-Welch Chair in the Department of Chemistry at Texas A&M University, with a joint appointment in the Department of Chemical Engineering. She received a B.S. in chemistry from Oregon State University in 1988 and then studied under the direction of Professor Jean M. J. Frechet at Cornell University, obtaining a Ph.D. in polymer/ organic chemistry in 1993. She began an academic career as an assistant professor of chemistry at Washington University in St. Louis, Missouri, was promoted in 1999 to full professor with tenure, and was installed as a James S. McDonnell Distinguished University Professor in Arts & Sciences in 2006. In 2009, she relocated to Texas A&M University. Research areas include the synthesis and characterization of degradable polymers, unique macromolecular architectures and complex polymer assemblies, and the design and development of well-defined nanostructured materials, for which she has received several awards, including an Arthur C. Cope Scholar Award, a Herman F. Mark Scholar Award, and awards from the National Science Foundation, the Office of Naval Research, and the Army Research Office. Karen serves as an Editor for the Journal of Polymer Science, Part A: Polymer Chemistry. 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