Cardiac output monitoring Vol. 60, No. 4, April 2011 The patients’ characteristics are listed in Table 1. All the patients (Table 3, Fig. 1). were in normal sinus rhythm throughout the study period. The results of the subgroup analyses according to the LVEF, The hemodynamic data is listed in Table 2. The CVP and SVRI CCI, MAP, SVRI and norepinephrine use are listed in Table 4 were significantly increased, and the SvO2, CCI and FCI were all significantly decreased at T3 compared to each baseline value. Overall, the CCI and FCI values were 2.7 ± 0.5 L/min/m2 (range: 1.4-4.5) and 2.6 ± 0.4 L/min/m2 (range: 1.6-4.1), respectively. Bland-Altman analysis of the FCI and CCI values demonstrated an overall mean bias and a limit of agreement of -0.07 and 0.67 L/min/m2, respectively, resulting in a percentage error of 26.9%. and Fig 1. The data pairs of the patients with a decreased LVEF (< 40%) or CCI ≤ 2.4 L/min/m2 all demonstrated a percentage error of < 30%. The data pairs divided according to a MAP of 60-80 mmHg and norepinephrine use also demonstrated a percentage error of < 30%. However, the data pairs of a SVRI of either < 1,600 or > 2,600 dyne s/cm5/m2 demonstrated a percentage error of 40.2% in contrast to the percentage error of The bias, limit of agreement and percentage error at various 15.5% for the data pairs of a SVRI between 1,600 and 2,600 dyne predefined time points of measurement were all acceptable. s/cm5/m2. Table 3. Bland-Altman Analyses of the Cardiac Index Bias (L/min/m2) Limit of agreement (L/min/m2) % error T1 -0.23 0.78 28.9 T2 -0.12 0.52 19.6 T3 0.10 0.56 26.4 T4 -0.05 0.60 23.5 T5 -0.08 0.60 24.1 Total -0.07 0.67 26.9 The table presents the Bland-Altman analyses of the cardiac index as measured by the FloTrac/VigileoTM system and the pulmonary artery catheter. T1: 15 min after induction of anesthesia, T2: during Y-graft construction with opened pericardium, T3: 5 min after applying stabilizer for creating an obtuse marginalis branch anastomosis, T4: 15 min after completion of grafting with opened pericardium, T5: 15 min after sternum closure. Fig. 1. Modified Bland-Altman analysis for repeated measures of agreement between the continuous cardiac index as measured by the FloTrac/VigileoTM system (FCI) and a pulmonary artery catheter (CCI). (A) Overall, 250 data pairs, (B) 20 patients with a left ventricular ejection fraction < 40%, 100 data pairs, (C) 30 patients with left ventricular ejection fraction ≥ 40%, 150 data pairs. The 2 unit of bias and the limit of agreement are L/min/m . 240 www.ekja.org