Mucke Patent number wO/2011/008001 Assignee and country CJ Cheiljedang (KR) wO/2011/004040 wO/2011/004038 Universidad de Sevilla (eS) wO/2010/150921 Teijin Pharma (JP) wO/2010/148411 entelos (US) Table 1 international patent applications concerning arterial hypertension, July 2010 to January 2011 wO/2010/137336 Kowa (JP) wO/2010/146551 wO/2010/143059 wO/2010/142794 wO/2010/129379 wO/2010/127096 wO/2010/124201 wO/2010/124120 Ranbaxy Laboratories (iN) Generex Pharmaceuticals (CA) Bios international (iT) Merck Sharpe and Dohme (US) Midwestern University (US) invasc Therapeutics (US) Mercator Medsystems (US) wO/2010/119700 Kowa (JP) wO/2010/116282 Pfizer (US) 268 submit your manuscript | www.dovepress.com Dovepress Subject Antihypertensive composition containing a ginsenosides enriched fraction of ginseng extract Captopril or L-carnitine for controlling the cardiac inflammatory process that accompanies arterial hypertension A 2-phenylthiazole agent for hypertension or high-normal blood pressure Novel computer models of hypertension comprising a renin- angiotensin-aldosterone system (RAAS) pathway module, a renal function module, and a blood pressure regulation module Orally disintegrating compositions comprising angiotensin ii receptor antagonists for hypertensive crisis Geum japonicum plant extracts for preventing or treating hypertension Non-enzymatic in vitro method for detecting gp91phox as a marker of oxidative stress, including hypertension, atherosclerosis, cardiac hypertophy, and stroke Alpha-phenoxybenzeneacetic acid derivatives that are angiotensin ii receptor antagonists and PPARgamma agonists, for hypertension and metabolic syndrome inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1) with diuretic and natriuretic action for hypertension and chronic and acute heart failure Centhaquin and related adrenergic agents for treating hypertension, pain, and resuscitative hemorrhagic shock Methylenedioxyphenyl ferulate, ferulylproline, and derivatives thereof as myeloperoxidase inhibitors and vasodilators for cardiovascular diseases Minimally invasive surgery with local application of guanethidine into the adventitia to reduce the activity of the sympathetic nerves surrounding the renal artery, for the treatment of renal and arterial hypertension Dual angiotensin ii receptor antagonist and PPARgamma agonist, for hypertension and metabolic syndrome 4,5-Dihydro-1H-pyrazole mineralocorticoid receptor antagonists for diabetic nephropathy and hypertension Dovepress Companion paper None J Inlfamm (Lond). 2010;7:21 and J Physiol Biochem. 2010;66(2):127–136 None Published January 20, 2011 January 13, 2011 December 29, 2010 December 23, 2010 None December 23, 2010 None December 16, 2010 December 16, 2010 None None December 2, 2010 None November 11, 2010 None November 4, 2010 October 28, 2010 None None October 28, 2010 None October 21, 2010 None October 14, 2010 J Med Chem. 2010;53(16):5979–6002 (Continued) Vascular Health and Risk Management 2011:7