Reduction in Visceral Adiposity is Highly Related to Improvement in Vascular Endothelial Dysfunction among Obese Women however, some questions have been raised about the validity and clinical utility of pulse wave analysis. Wide margins of error were found when comparing centrally measured and peripherally derived AIx.30 AIx was also found to be depen- dent on heart rate and blood pressure during IV infusion of beta-adrenergic drugs, such as isopro- terenol.31 However, the inhalation of albuterol was not accompanied by significant alterations in heart rate and MAP.5 We also confirmed in a previous study that a substantial change in heart rate or MAP was not induced by NTG or salbutamol. In the present study, changes in AIx-Salb by weight reduction were not related to a small change in heart rate or diastolic or systolic pres- sure (Table 3). 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