A A C B B D So-Young Jin. Sclerosed hemangioma of the liver 411 Figure 1. Gross appearance of the sclerosed hemangioma. A gray-white sunken nodule is noted in the subcapsular area (A). The cut surface discloses a well-demarcated homogenous gray-white solid nodule, measuring 2.1 cm at its greatest dimension, with tiny red spots (B). Figure 2. (A) Histologic features of the sclerosed hemangioma nodule in the right lobe. A hyalinized mass is identified from the surrounding liver. (B) This mass consists of collapsed vascular spaces on the rich paucicellular fibrous stroma. (C) The vascular spaces are easily identified on immunohistochemistry for an endothelial marker. (D) Sclerosis is highlighted with a special stain, Masson’s trichrome (A: H-E, ×12.5; B: H-E, ×200; C: factor-VIII-related antigen, ×100, D: Masson’s trichrome, ×40). cm. A bulging mass lesion was present that measured 3.5×2.7 hepatocellular carcinoma of Edmondson-Steiner grade II with cm. On sectioning, the mass was well circumscribed from the foci of portal vein invasion. surrounding noncirrhotic liver and its cut surface was yellow- The wedge-resected liver from segment 6 weighed 8 g ish/greenish-gray in color. Microscopic examination disclosed a and measured 3.8×2.8×2.0 cm. The external Glisson’s capsule