Int. J. Environ. Res. Public Health 2009, 6 1003 status were not significantly different between GG and GC genotypes in the present study (Table 1), where these were known confounding variables for ALAD enzyme activity [24,25]. Furthermore, in Figure 1, the prevalence of blood lead levels from 1μg/dL to 5 μg/dL in GG genotype was much higher than that in GC genotype, but a 7μg/dL blood lead level was more prevalent in GC than that in GG genotype. Even in the all non-occupationally lead exposed participants, the blood lead level was shifted from the left to the right in ALAD2 carrier genotype (GC). Our finding is similar to that of the other studies [16-19]. Table 1. Basic characteristics of non-occupationally lead exposed subjects. All non lead exposed ALAD genotype participants GG GC (N=101) (N=84) (N=17) Demographics and Clinical Sex (Male/Female) Age (years) Smoking (Yes/No) Height, cm Weight, kg Body mass index, kg/m2 SBP, mmHg DBP, mmHg Complete Blood Counts White blood cell count, 103/μL Red blood cell count, 106/μL Hemoglobin, g/dL Hematocrit, % Platelet count, 103/μL Biochemical AST/GOT, IU/l # ALT/GPT, IU/l # γ-GTP, IU/l 73/28 43.4 (11.9) 55/46 166.3 (8.3) 65.0 (13.7) 23.4 (4.1) 130.2 (18.8) 78.8 (13.0) 61.2 (14.7) 465.6 (41.6) 14.4 (1.6) 43.7 (4.0) 24.9 (4.9) 22.2 (1.4) 22.7 (1.8) 34.0 (2.1) 61/23 43.2 (11.9) 45/39 166.4 (8.2) 65.3 (14.4) 23.4 (4.2) 128.7 (17.4) 78.3 (12.6) 59.7 (13.8) 465.1 (42.2) 14.3 (1.6) 43.6 (4.0) 24.9 (4.6) 22.1 (1.4) 22.8 (1.9) 32.8 (2.0 12/5 44.5 (12.2) 10/7 165.5 (9.2) 63.8 (9.6) 23.3 (3.6) 137.7 (23.9) 81.1 (15.1) 68.4 (17.6) 468.1 (40.0) 14.7 (1.7) 44.1 (4.3) 25.0 (6.1) 22.4 (1.4) 22.0 (1.6) 40.9 (2.6) P 0.54 0.68 0.81 0.66 0.68 0.94 0.15 0.43 0.02 0.79 0.37 0.65 0.94 0.90 0.81 0.38