Del Pup L et al. / Vaginal cytology in gynecological cancer 169 The effectiveness of vaginal vault cytology in the above mentioned studies could have been different, if performed with the cytobrush. We used both the cytobrush and the Ayre’s spatula for vaginal vault sampling. Smear preparation was made according to standard pathological operative procedures. In our study, we did not use liquid based cytology to increase the whole number of collected cells be- cause the main goal of the study was to compare two sampling methods conducted by means of two different devices. In conclusion, our data revealed that, in women with gynecological cancers, vaginal vault cytology conducted with the cytobrush appeared more effi- cient than its conventional counterpart, the Ayre’s spatula, as it allowed the collection of a more ad- equate sample. References 1. Velenik V. Post-treatment surveillance in colorectal cancer. Radiol Oncol 2010; 44: 135-41. 2. Strojan Flezar M. Urine and bladder washing cytology for detection of urothelial carcinoma: standard test with new possibilities. Radiol Oncol 2010; 44: 207-14. 3. Cooper AL, Dornfeld-Finke JM, Banks HW, Davey DD, Modesitt SC Is cyto- logic screening an effective surveillance method for detection of vaginal recurrence of uterine cancer? Obstet Gynecol 2006; 107: 71-6. 4. Kew FM, Roberts AP, Cruickshank DJ. The role of routine follow-up after gynecologic malignancy. Int J Gynecol Cancer 2005; 15: 413-9. 5. Martin-Hirsch P, Lilford R, Jarvis G, Kitchener HC. Efficacy of cervical-smear collection devices: a systematic review and meta-analysis. Lancet 1999; 354: 1763-70. 6. Gemmell J, Holmes DM, Duncan I. How frequently need vaginal smears be taken after hysterectomy for cervical intraepithelial neoplasia? Br J Obstet Gynaecol 1990; 97: 58-61. 7. Mouithys P, Papadopoulos C, Allier G, Lanta S, Delpierre C, Najas S, et al. Faut-il poursuivre les frottis de dépistage après hystérectomie? Gynecol Obstet Fertil 2003; 31: 620-3. 8. Agboola O, Grunfeld E, Coyle D, Perry GA Costs and benefits of routine follow-up after curative treatment for endometrial cancer. Can Med Assoc 1997; 157: 879-86. 9. Bristow RE, Purinton SC, Santillan A. Cost-effectiveness of routine vaginal cytology for endometrial cancer surveillance. Gynecol Oncol 2006; 103: 709-13. 10. Allsop JR, Preston J, Crocker S. Is there any value in the long term follow up of women treated for endometrial cancer? Br J Obstet Gynaecol 1997; 104: 119-22. 11. Shumsky AG, Stuart G., Brasher PM, Nation JG, Robertson DI, Sangkarat S. An evaluation of routine follow-up of patients treated for endometrial carcinoma. Gynecol Oncol 1994; 55: 229-33. 12. Ackerman I, Malone S, Thomas G, Franssen E, Balogh J, Dembo A. Endometrial carcinoma - relative effectiveness of adjuvant irradiation vs therapy reserved for relapse. Gynecol Oncol 1996; 60: 177-83. 13. Ball HG. Do we know the best therapy for early endometrial cancer? Gynecol Oncol 1996; 60: 173-5. 14. Fung-Kee-Fung M, Dodge J, Elit L, Lukka H, Chambers A, Oliver T. Follow-up after primary therapy for endometrial cancer: A systematic review. Gynecol Oncol 2006; 101: 520-9. Radiol Oncol 2012; 46(2): 166-169.