P o s t S c r i p t tumourigenesis of such lesions. In the present case, no manifestations of immu- nodeﬁciency were observed. Furthermore, HHV-8 was only detectable in KS cells. Therefore, the concurrent occurrence of the two neoplastic components seemed more likely coincidental rather than aetiologically related. Clinically, chemotherapy with radiotherapy seems a promising way for the treatment of such cases, and the ABVD regimen looks like a proper choice. He-Qin Zhan,1,2 Xiao-Qiu Li,1,2 Xiong-Zeng Zhu,1,2 Ye Guo,2,3 Hong-Fen Lu,1,2 Feng Li4 1Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, PR China; 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, PR China; 3Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China; 4Department of Pathology, College of Medicine, Shihezi University, Shihezi, PR China Correspondence to Dr Xiao-Qiu Li, Department of Pathology, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai 200032, PR China; leexiaoqiu@hotmail.com Competing interests None. Patient consent Obtained. Provenance and peer review Not commissioned; externally peer reviewed. Published Online First 30 June 2010 J Clin Pathol 2010;63:756e758. doi:10.1136/jcp.2010.078535 REFERENCES 1. Poppema S, Delsol G, Pileri SA, et al. Nodular lymphocyte predominant Hodgkin lymphoma. In: Swerdlow SH, Campo E, Harris NL, et al, eds. WHO classiﬁcation of tumours of haematopoietic and lymphoid tissues. World Health Organization classiﬁcation of tumours. Lyon, France: IARC Press, 2008:323e5. 2. Lamovec J, Knuutila S. Kaposi sarcoma. In: Fletcher CD, Unni KK, Mertens F, eds. Pathology and genetics of tumours of soft tissue and bone. World Health Organization classiﬁcation of tumours. Lyon, France: IARC Press, 2002:170e2. 3. Mitsuyasu RT, Colman MF, Sun NC. Simultaneous occurrence of Hodgkin’s disease and Kaposi’s sarcoma in a patient with the acquired immune deﬁciency syndrome. Am J Med 1986;80:954e8. 4. Jung CP, Gurtler L, Goebel FD. Hodgkin’s disease related Kaposi’s sarcoma in a non-HIV infected male patient: a case report and review of the literature on a rare condition. Eur J Med Res 2000;5:311e17. Keratocystoma of the parotid gland: case report and immunohistochemical investigation Keratocystoma of the parotid gland was ﬁrst deﬁned and reported as an unusual patho- logical entity in 2002.1 It was not listed as an independent pathological entity in the revised World Health Organization (WHO) classiﬁcation of salivary gland tumours published in 2005.2 Recently, the designation of keratocystoma of the parotid gland was introduced as a newly recognised diagnosis.3 Here, we present a case of a benign tumour of the parotid gland diagnosed as a kerato- cystoma. CASE REPORT A 37-year-old man presented with a painless circumscribed nodule that had been gradu- ally enlarging in the left parotid gland area for six years. No cervical lymphadenopathy was detected. A subtotal parotidectomy was performed and a tumour was excised. No tumour recurrence was observed 18 months after the surgery. Grossly, the tumour was completely circumscribed within the parotid gland, measuring 20318315 mm in size. The cut surface revealed multilocular cystic spaces. No bleeding or necrosis was detected in the tumour. Histologically, the tumour consisted mainly of multiple cystic formations lined with stratiﬁed squamous epithelium lacking a granular layer, but containing keratin material and calciﬁcation (ﬁgure 1). There was no evidence of cytological atypia or abnormal mitotic activity in the epithelium. No tubules, duct-like glandular structures, or sebaceous differentiation were observed. No evidence of skin appendages was found beneath the epithelium. The stroma of the tumour was predominantly a dense Figure 1 H&E stained sections showing the keratocystoma morphology. (A) Characteristic tumour view consisting of variably sized and shaped cystic lesions ﬁlled with lamellar keratin material and calciﬁcation (320). (B) The stroma of the tumour showing predominantly a dense lymphoid element (3100). (C) The stratiﬁed squamous epithelium lacking a granular layer ﬁlled with lamellar keratin material (3200). (D) Solid squamous cell islands exhibiting uniform, bland nuclei and abundant eosinophilic cytoplasm (3400). 758 J Clin Pathol August 2010 Vol 63 No 8