10 [51] T. O. Kiviniemi, A. Saraste, J. O. Toikka et al., “A moderate dose of red wine, but not de-alcoholized red wine increases coronary ﬂow reserve,” Atherosclerosis, vol. 195, no. 2, pp. e176–e181, 2007. [52] A. Imhof, I. Plamper, S. Maier, G. Trischler, and W. Koenig, “Eﬀect of drinking on adiponectin in healthy men and women: a randomized intervention study of water, ethanol, red wine, and beer with or without alcohol,” Diabetes Care, vol. 32, no. 6, pp. 1101–1103, 2009. [53] S. N. Blair, W. B. Kannel, H. W. Kohl, N. Goodyear, and P. W. F. Wilson, “Surrogate measures of physical activity and physical ﬁtness. Evidence for sedentary traits of resting tachycardia, obesity, and low vital capacity,” American Journal of Epidemiology, vol. 129, no. 6, pp. 1145–1156, 1989. [54] R. P. Murray, J. E. Connett, S. L. Tyas et al., “Alcohol volume, drinking pattern, and cardiovascular disease morbidity and mortality: is there a u-shaped function?” American Journal of Epidemiology, vol. 155, no. 3, pp. 242–248, 2002. [55] R. Clarke, C. Frost, R. Collins, P. Appleby, and R. Peto, “Dietary lipids and blood cholesterol: quantitative meta- analysis of metabolic ward studies,” British Medical Journal, vol. 314, no. 7074, pp. 112–117, 1997. [56] C. L. Hart and G. D. Smith, “Alcohol consumption and mortality and hospital admissions in men from the Midspan Collaborative cohort study,” Addiction, vol. 103, no. 12, pp. 1979–1986, 2008. [57] I. H. M. Friesema, P. J. Zwietering, M. Y. Veenstra, J. A. Knottnerus, H. F. L. Garretsen, and P. H. H. M. Lemmens, “Alcohol intake and cardiovascular disease and mortality: the role of pre-existing disease,” Journal of Epidemiology and Community Health, vol. 61, no. 5, pp. 441–446, 2007. [58] L. W. Gibbons, T. L. Mitchell, M. Wei, S. N. Blair, and K. H. Cooper, “Maximal exercise test as a predictor of risk for mortality from coronary heart disease in asymptomatic men,” American Journal of Cardiology, vol. 86, no. 1, pp. 53–58, 2000. [59] G. J. Balady, M. G. Larson, R. S. Vasan, E. P. Leip, C. J. O’Donnell, and D. Levy, “Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic per- sons as a function of the Framingham risk score,” Circulation, vol. 110, no. 14, pp. 1920–1925, 2004. Journal of Aging Research