Compliance with antihypertensive treatment Ortega KC et al. Table 2 - Blood pressure (mmHg) at the beginning and end of the 12-month treatment in the ‘‘uncomplicated’’ and ‘‘complicated’’ groups, according to the ‘‘traditional’’ and ‘‘current’’ treatments and randomization into the ‘‘phone calls’’ and ‘‘no phone calls’’ groups. Group Randomization Visit Final Visit Uncomplicated (n = 179) 155¡12/91¡10 126¡14*/73¡11* ‘‘Traditional’’ Treatment (n = 90) 155¡12/91¡9 126¡14*/71¡11* ‘‘Current’’ Treatment (n = 89) 155¡12/92¡10 126¡15*/74¡11* ‘‘No Phone Calls’’ (n = 119) 156¡13/91¡10 127¡16*/73¡12* ‘‘Phone Calls’’ (n = 60) 154¡11/92¡9 125¡11*/73¡10* Complicated (n = 175) 163¡24/102¡20 131¡19*/78¡14* ‘‘Traditional’’ Treatment (n = 86) 164¡24/102¡21 132¡21*/77¡16* ‘‘Current’’ Treatment (n = 89) 161¡23/102¡19 130¡18*/78¡12* ‘‘No Phone Calls’’ (n = 127) 162¡23/102¡19 132¡20*/79¡15* ‘‘Phone Calls’’ (n = 48) 163¡25/103¡22 127¡18*/75¡11* Data are shown as mean¡s.d.; *p, 0.00001 – Randomization Visit versus Final Visit. The percentage of patients with controlled blood pressure (,140/90 mmHg) was also high at the end of treatment (74%). On the other hand, the percentage of patients with blood pressure reduced to ,120/80 mmHg was only 29%. There was no difference in the percentage of patients with controlled blood pressure between the ‘‘phone calls’’ and ‘‘no phone calls’’ groups or in the reduction of blood pressure and the percentage of patients with controlled blood pressure among the ‘‘traditional’’ and ‘‘current’’ treatments. However, patients in the ‘‘phone calls’’ group (80%) had better blood pressure control than those in the ‘‘no phone calls’’ group (71%), though the difference was not statistically significant. The ‘‘uncomplicated’’ and ‘‘complicated’’ groups had statistically significant differ- ences in the percentage of patients with controlled blood pressure (,140/90 mmHg) (80% vs. 67%, respectively; p,0.000001). At the next to last study visit (visit 7), 90% CLINICS 2010;65(9):857-863 Table 3 - Percentage of patients with controlled blood pressure at the beginning (randomization visit), at the next-to-last visit (visit 7) and at the end (visit 8-final) of the 12-month treatment period. Group ‘‘Uncomplicated’’ ‘‘Complicated’’ ‘‘Traditional’’ Treatment ‘‘Current’’ Treatment ‘‘Phone Calls’’ ‘‘No Phone Calls’’ Total Randomization Visit Visit 7 Final Visit 0*/0** 16/6 8/3 11/3 8/3 8/3 8/3 90*/31 66/31 75/32 81/30 84/32 75/30 78/31 80/30 67/28 73/31 74/27 80/33 71/27 74/29 Controlled blood pressure: , 140/90 mmHg/120/80 mmHg. p .0.05, except: N *Uncomplicated versus complicated: Randomization visit - x21 = 28.94; p,0.000001 (SBP,140/DBP,90) N **Uncomplicated versus complicated: Randomization visit - x21 = 8.55; p = 0.0035 (SBP,120/DBP,80) N Uncomplicated versus complicated: Visit 7 - x21 = 28.84; p,0.000001 (SBP,140/DBP,90) and 66% of patients had blood pressure measurements ,140/90 mmHg in the ‘‘uncomplicated’’ and ‘‘compli- cated’’ groups, respectively. However, there was no difference in the percentage of patients with blood pressure ,120/80 mmHg (31% on the final visit in both groups, Table 3). Among patients with a blood pressure ,140/90 mmHg at the final visit, only 3% had received only one type of antihypertensive medication; most patients (56%) received 2 (34%) or 3 (22%) types of antihypertensive medication (Table 4). b) Treatment Discontinuation A significantly lower number of patients in the ‘‘phone calls’’ group quit the treatment compared to the ‘‘no phone Figure 1 - IASH 2009 How to avoid discontinuation of antihypertensive treatment: the experience in S a˜o Paulo, Brazil. 860