210 K. Sugimoto et al. kidney disease, and cardiovascular disease. Am. J. Clin. Nutr., 86, 899–906, 2007. [3] Dwyer, J.T., Evans, M., Stone, E.J., Feldman, H.A., Lytle, L., Hoelscher, D., Johnson, C., Zive, M., and Yang, M.: Adolescents’ eating patterns influence their nutrient intakes. J. Am. Diet. Assoc., 101, 798–802, 2001. [4] Fukuda, H., Iritani, N., and Tanaka, T.: Effects of high- fructose diet on lipogenic enzymes and their substrate and effector levels in diabetic rats. J. Nutr. Sci. Vitaminol., 29, 691–699, 1983. [5] Elliott, S.S., Keim, N.L., Stern, J.S., Teff, K., and Havel, P.J.: Fructose, weight gain, and the insulin resistance syndrome. Am. J. Clin. Nutr., 76, 911–922, 2002. [6] Stanhope, K.L. and Havel, P.J.: Fructose consumption: potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance. Curr. Opin. Lipidol., 19, 16–24, 2008. [7] Stanhope, K.L., Schwarz, J.M., Keim, N.L., Griffen, S.C., Bremer, A.A., Graham, J.L., Hatcher, B., Cox, C.L., Dyachenko, A., Zhang, W., McGahan, J.P., Seibert, A., Krauss, R.M., Chiu, S., Schaefer, E.J., Ai, M., Otokozawa, S., Nakajima, K., Nakano, T., Beysen, C., Hellerstein, M.K., Berglund, L., and Havel, P.J.: Consuming fructose- sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J. Clin. Invest., 119, 1322– 1334, 2009. [8] Tanaka, K., Moriya, T., Kanamori, A., and Yajima, Y.: Analysis and a long-term follow up of ketosis-onset Japanese NIDDM patients. Diabetes Res. Clin. Pract., 44, 137–146, 1999. [9] Igarashi, K., Kawasaki, T., Ogata, N., Sakai, T., Ichiyanagi, K., Fujimori, S., and Yamanouchi, T.: A case of soft-drink ketosis concomitant with extremely elevated serum fructose concentrations. J. Jpn. Diabetes Soc., 49, 417–421, 2006 (in Japanese). [10] American Diabetes Association: Nutrition recommendations and interventions for diabetes: A position statement of the American Diabetes Association. Diabetes Care, 30, S48–65, 2007. [11] Osaki, S., Kimura, T., Sugimoto, T., Hizukuri, S., and Iritani, N.: L-arabinose feeding prevents increases due to dietary sucrose in lipogenic enzymes and triacylglycerol levels in rats. J. Nutr., 131, 796–799, 2001. [12] Gray, A.M. and Flatt, P.R.: Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J. Nutr., 128, 2319–2323, 1998. [13] Sugimoto, K., Suzuki, J., Nakagawa, K., Hayashi, S., Enomoto, T., Fujita, T., Yamaji, R., Inui, H., and Nakano, Y.: Eucalyptus leaf extract inhibits intestinal fructose absorption, and suppresses adiposity due to dietary sucrose in rats. Br. J. Nutr., 93, 957–963, 2005. [14] Kawasaki, T., Akanuma, H., and Yamanouchi, T.: Increased fructose concentrations in blood and urine in patients with diabetes. Diabetes Care, 25, 353–357, 2002. [15] Julkunen-Tiitto, R.: Phenolic constituents in the leaves of northern willows: Methods for the analysis of certain phenolics. J. Agric. Food Chem., 33, 213–217, 1985. [16] Prieto, P.G., Cancelas, J., Villanueva-Peñacarrillo, M.L., Valverde, I., and Malaisse, W.J.: Plasma D-glucose, D- fructose and insulin responses after oral administration of D-glucose, D-fructose and sucrose to normal rats. J. Am. Coll. Nutr., 23, 414–419, 2004. [17] Macdonald, I. and Turner, U.: Serum fructose levels after sucrose or its constituent monosaccharides. Lancet, 1, 841– 843, 1968. [18] Crossley, J.N. and Macdonald, I.: The influence in male baboons of a high sucrose diet on the portal and arterial levels of glucose and fructose following a sucrose meal. Nutr. Metab., 12, 171–178, 1970. [19] Topping, D.L. and Mayer, P.A.: The concentrations of fructose, glucose and lactate in the splanchnic blood vessels of rats absorbing fructose. Nutr. Metab., 13, 331–338, 1971. [20] Truswell, A.S., Seach, J.M., and Thorburn, A.W.: Incomplete absorption of pure fructose in healthy subjects and the facili- tating effect of glucose. Am. J. Clin. Nutr., 48, 1424–1430, 1988. [21] Chong, M.F.-F., Fielding, B.A., and Frayn, K.N.: Mecha- nisms for the acute effect of fructose on postprandial lipemia. Am. J. Clin. Nutr., 85, 1511–1520, 2007. [22] Pitkänen, E. and Kanninen, T.: Determination of mannose and fructose in human plasma using deuterium labelling and gas chromatography/mass spectrometry. Biol. Mass Spectrom., 23, 590–595, 1994. [23] Mayes, P.A.: Intermediary metabolism of fructose. Am. J. Clin. Nutr., 58, 754S–765S, 1993. [24] Colaco, C.A.L.S.: Sucrose as a dietary risk factor in athero- sclerosis: A biochemical addendum, in The Glycation Hypo- thesis of Atherosclerosis, ed. By Colaco, C.A.L.S., Landes Bioscience (USA) Limited, Georgetown, Texas, pp. 175– 183, 1997. [25] Bunn, H.F. and Higgins, P.J.: Reactions of monosaccharides with proteins; possible evolutionary significance. Science, 213, 222–224, 1981. [26] Schalkwijk, C.G., Stehouwer, C.D., and van Hinsbergh, V.W.: Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification. Diabetes Metab. Res. Rev., 20, 369–382, 2004. [27] Krajcovicová-Kudlácková, M., Sebeková, K., Schinzel, R., and Klvanová, J.: Advanced glycation end products and nutrition. Physiol. Res., 51, 313–316, 2002. [28] Levi, B. and Werman, M.J.: Long-term fructose consumption accelerates glycation and several age-related variables in male rats. J. Nutr., 128, 1442–1449, 1998. [29] Mikulíková, K., Eckhardt, A., Kunes, J., Zicha, J., and Miksík, I.: Advanced glycation end-product pentosidine accumulates in various tissues of rats with high fructose intake. Physiol. Res., 57, 89–94, 2008. [30] Hou, A.J., Liu, Y.Z., Yang, H., Lin, Z.W., and Sun, H.D.: Hydrolyzable tannins and related polyphenols from Eucalyp- tus globulus. J. Asian Nat. Prod. Res., 2, 205–212, 2000. [31] Amakura, Y., Yoshimura, M., Sugimoto, N., Yamazaki, T., and Yoshida, T.: Marker constituents of the natural anti- J. Clin. Biochem. Nutr.