Gastric Schwannoma Fig. 1. Barium upper gastrointestinal study shows a large submucosal tumor noted in gastric angle without mucosal ulceration (black arrows). Fig. 3. Abdomen sonography reveals a homogeneous, hypoechoic and kidney bean shaped mass. Fig. 2. Abdomen computed tomography reveals a large soft tissue mass lesion along lesser curvature side of stomach (black arrow). The patient underwent a subtotal gastrectomy. On gross inspection, the tumor was an exophytic, intramural, fungating, nodular, solid mass mea- suring 6 × 5.5 × 4 cm with whirling trabeculation seen in cross section (Fig. 4). Immunohistochemically, the tumor was positive for S-100 protein, while desmin and smooth muscle actin were negative. These morphologic features were identical to those of previously reported digestive tract schwannomas (Fig. 5). Three years after surgery, the patient is well and without evidence of recurrent disease. Fig. 4. Surgical specimen is seen a intramural fungating nodular solid mass. Fig. 5. Immunochemistry stain shows the bundles of spindle cell with brown color, positive to S-100 protein (S- 100 stain, × 200). Yonsei Med J Vol. 49, No. 6, 2008