Table 6. Seroprevalence among patients of diseases other than Liver Disease. Author Year Place Disease Medical Diseases Khan 2004 Mardan General 700 Mumtaz & Aftab 2005 Rawalpindi General 264 Gul & Iqbal 2003 Lahore Renal Failure 50 Khokar et al. 2005 Islamabad Renal Failure 97 Qazi et al. 2004 Bahawalpur Diabetes 2 250 Bilwani et al. 2004 Karachi Lymphoprolifrative 143 Total 1504 Number Karachi Peshawar (Thalassemia) Islamabad Islamabad Peshawar Total Islamabad Karachi Nawabshah Abbottabad Jacobabad Total β-Thalassemia β-Thalassemia β-Thalassemia β-Thalassemia Haemophillia Depression Surgical Diseases Surgical Diseases Orthopaedic Diseases Surgical Diseases Haematological Diseases Moatter et al. Muhammad J Younus et al. Burki et al. Hussain Psychological Diseases Shah & Dar Surgical Diseases Hussain & Fatima Talpur et al. Khan et al. Daudpota & Soomro Dental Diseases Khitab et al. 1999 2003 2004 2005 2001 2004 2005 2006 2007 2008 2005 Author Pregnant Women Khan Parker Zafar et al. Bilal Rizvi Fayyaz Khokar et al. Jaffery Yousafani et al. Hakeem et al. Batool et al. 100 80 75 180 40 475 135 750 180 1630 150 2710 1,498 Muhammad Umar et al. 209 Anti HCV (%) Reference 9.0 (10) 28.6 (70) 68.0 (71) 23.7 (72) 27.6 (73) 29.2 (89) 20.4 (95% CI = 18.4-22.5) 35.0 (106) 36.2 (126) 42.0 (94) 41.7 (74) 25.0 (14) 38 (95% CI = 33.6-42.5) 22.9 (80) 16.2 (81) 11.9 (82) 3.1 (83) 14.0 (84) 7.9 (95% CI = 6.9-9.0) Peshawar Dental Diseases Diseases 1.3 (85) Table 7. Seroprevalence among Pregnant women. Year Place Number Anti HCV (%) Reference 1996 1999 2001 2002 2002 2004 2004 2005 2006 2006 2008 Total Lahore Lahore Lahore Peshawar Karachi Lahore Islamabad Islamabad Hyderabad RY Khan Lahore 417 417 300 352 120 100 503 947 103 450 2,439 6,148 9.3 (56) 4.0 (90) 6.0 (88) 5.1 (74) 6.6 (80) 7.0 (91) 4.8 (92) 3.3 (93) 29.1 (94) 18.2 (41) 7.3 (99) 7.3 (95% CI = 6.7 – 8.0) 36.25%. The mean frequency was 1.8% (95% CI = 4.6 – 7.5). One study from Lahore in 1996 reported a 4.1% perinatal transmission of HCV in children of HCV- positive mothers. The serofrequency of HCV in thalassemics, and hemophiliacs was 35-42% (75- 78) and 25% (79), respectively. Discussion Many researchers have tried to derive a national or regional figure for HCV serofrequency based on the available data (99-101). In 2005, Umar M and Khaar HTB (99), from Rawalpindi, collected data from various studies and reported a 9.8% frequency in 79,192 individuals. In 2006, Hafeez (99), from Islamabad, collected data from 98 studies and produced an estimate of 5.3%. Raja and Janjua (101), from Essex (UK), analyzed studies available on Medline from 1970 to 2005, and observed that the prevalence of HCV infection ranges from 0.4% in children, to 1.2% in healthy blood donors. Ali et al. Hepatitis Monthly, Summer 2010; 10(3): 205-214