the Work Area. Berlin. www2.dupont.com/Plastics/en_US/assets/ downloads/processing/FETEG_Facts.pdf. Main DM, Hogan TJ. (1983). Health effects of low-level exposure to formaldehyde. J Occup Med 25:896–900. Malaka T, Kodama AM. (1990). Respiratory health of plywood workers occupationally exposed to formaldehyde. Arch Environ Health 45:288–294. Marsh GM, Youk AO. (2004). Reevaluation of mortality risks from leukemia in the formaldehyde cohort study of the National Cancer Institute. Regul Toxicol Pharmacol 40:113–124. Marsh GM, Youk AO. (2005). Reevaluation of mortality risks from nasopharyngeal cancer in the formaldehyde cohort study of the National Cancer Institute. Regul Toxicol Pharmacol 42:275–283. Marsh GM, Youk AO, Buchanich JM, Cassidy LD, Lucas LJ, Esmen NA, Gathuru IM. (2002). Pharyngeal cancer mortality among chemical plant workers exposed to formaldehyde. Toxicol Ind Health 18:257–268. Marsh GM, Youk AO, Buchanich JM, Erdal S, Esmen NA. (2007). Work in the metal industry and nasopharyngeal cancer mortality among formaldehyde-exposed workers. Reg Toxicol Pharmacol 48:308–319. McGregor D, Bolt H, Cogliano V, Richter-Reichhelm HB. (2006). Formaldehyde and glutaraldehyde and nasal cytotoxicity: Case study within the context of the 2006 IPCS Human Framework for the Analysis of a cancer mode of action for humans. Crit Rev Toxicol 36:821–35. McGwin G Jr, Lienert J, Kennedy JI Jr. (2010). Formaldehyde exposure and asthma in children: A systematic review. Environ Health Perspect 118:313–317. Meek ME, Bucher JR, Cohen SM, Dellarco V, Hill RN, Lehman- McKeeman LD, Longfellow DG, Pastoor T, Seed J, Patton DE. (2003). A framework for human relevance analysis of information on carcinogenic modes of action. Crit Rev Toxicol 33:591–653. Meininghaus R, Kouniali A, Mandin C, Cicolella A. (2003). Risk assessment of sensory irritants in indoor air—A case study in a French school. Environ Int 28:553–557. Meng F, Bermudez E, McKinzie PB, Andersen ME, Clewell HJ 3rd, Parsons BL. (2010). Measurement of tumor-associated mutations in the nasal mucosa of rats exposed to varying doses of formaldehyde. Regul Toxicol Pharmacol 57:274–283. Michielsen P, Vandewoude M. (2010). Liver diseases in the older adult. Acta Gastroenterol Belg 73:1–4. Moeller BC, Lu K, Doyle-Eisele M, McDonald J, Gigliotti A, Swenberg J.A. (2011). Determination of N2-hydroxymethyl-dG adducts in nasal epithelium and bone marrow of non-human primates following 13CD2-formaldehyde inhalation exposure. Chem Res Toxicol 24:162–164. Monticello TM, Swenberg JA, Gross EA, Leininger JR, Kimbell JS, Seilkop S, Starr TB, Gibson JE, Morgan KT. (1996). Correlation of regional and nonlinear formaldehyde-induced nasal cancer with proliferating populations of cells. Cancer Res 56:1012–1022. Moser B, Bodrogi F, Eibl G, Lechner M, Rieder J, Lirk P. (2005). Mass spectrometric profile of exhaled breath—Field study by PTR-MS. Respir Physiol Neurobiol 145:295–300. National Academy of Sciences (NAS). (2000). Clearing the Air: Asthma and Indoor Air Exposures. Washington, DC: Institute of Medicine. Available at: http://www.nap.edu/books/0309064961/html National Academy of Sciences (NAS). (2007a). Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment. Washington, DC: Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment, National Research Council. National Academy of Sciences (NAS). (2007b). Emergency and Continuous Exposure Guidance Levels for Selected Submarine Contaminants. Washington, DC: Subcommittee on Emergency and Continuous Exposure Guidance Levels for Selected Submarine Contaminants, Committee on Toxicology, National Research Council. National Academy of Sciences (2011). Review of the Environmental Protection Agency’s Draft IRIS Assessment of © 2011 Informa Healthcare USA, Inc. Indoor air exposure limit for formaldehyde 719 Formaldehyde. National Research Council, National Academy of Sciences, Washington, DC. http://www.nap.edu/catalog. php?record_id=13142 National Industrial Chemicals Notification and Assessment Scheme (NICNAS). (2006). Formaldehyde. Priority Existing Chemical Assessment Report. xx: Australian Department of Health and Ageing. Sydney. National Toxicology Program (NTP). (2009). Formaldehyde Expert Panel Report. Part B. Recommendation for Listing Status for FormaldehydeandScientificJustificationfortheRecommendation. Research Triangle Park, NC: NTP. Neuss S, Moepps B, Speit G. (2010). Exposure of human nasal epithelial cells to formaldehyde does not lead to DNA damage in lymphocytes after co-cultivation. Mutagenesis 25:359–364. Nielsen GD, Hougaard KS, Larsen ST, Hammer M, Wolkoff P, Clausen PA, Wilkins CK, Alarie Y. (1999). Acute airway effects of formaldehyde and ozone in BALB/c mice. Hum Exp Toxicol 18:400–409. Nielsen GD, Wolkoff P. (2010). Cancer effects of formaldehyde: A proposal for an indoor air guideline value. Arch Toxicol 84:423–446 Noisel N, le Bouchard M, Carrier G. (2007). Evaluation of the health impact of lowering the formaldehyde occupational exposure limit for Quebec workers. Regul Toxicol Pharmacol 48:118–127. Nordman H, Keskinen H, Tuppurainen M. (1985). Formaldehyde asthma—Rare or overlooked? J Allergy Clin Immunol 75:91–99. Office of Environmental Health Hazard Assessment (OEHHA). (2008). Chronic Toxicity Summary: Formaldehyde. Sacramental: California Environmental Protection Agency (Cal/EPA). Organization for Economic Cooperation and Development (OECD). (2002). Formaldehyde; SIDS Initial Assessment Profile at 17-18. Paris: UNEP Publications. Orsière T, Sari-Minodier I, Iarmarcovai G, Botta A. (2006). Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes. Mutat Res 605:30–41. Overton JH, Kimbell JS, Miller FJ. (2001). Dosimetry modeling of inhaled formaldehyde: The human respiratory tract. Toxicol Sci 64:122–134. Paustenbach DY, Alarie Y, Kulle T, Schachter N, Smith R, Swenberg J, Witschi H, Horowitz SB. (1997). A recommended occupational exposure limit for formaldehyde based on irritation. J Toxicol Environ Health 50:217–263. Paustenbach DJ, Gaffney SH. (2006). The role of odor and irritation as well as risk perception in the setting of occupational exposure limits. Int Arch Occup Environ Health 79:339–342. Pazdrak K, Gorski P, Krakowiak A. (1993). Changes in nasal lavage fluid due to formaldehyde inhalation. Int Arch Occup Environ Health 64:515–519. Pinkerton LE, Hein MJ, Stayner LT. (2004). Mortality among a cohort of garment workers exposed to formaldehyde: An update. Occup Environ Med 61:193–200. Pross HF, Day JH, Clark RH. (1987). Immunological studies of subjects with asthma exposed to formaldehyde and urea-formaldehyde foam insulation (UFFI) off products. J Allergy Clin Immunol 79:797–810. Pyatt D, Natelson E, Golden R. (2008). Is inhalation exposure to formaldehyde a biologically plausible cause of lymphohematopoietic malignancies? Reg Toxicol Pharmacol 51:119–133. Reaven GM, Reaven EP. (1980). Effects of age on various aspects of glucose and insulin metabolism. Mol Cell Biochem 31:37–47. Rhomberg LR, Bailey LA, Goodman JE, Hamade A, Mayfield D. (2011). Is exposure to formaldehyde in air causally associated with leukemia?—A hypothesis-based weight-of-evidence analysis. Crit Rev Toxicol In press. Riess U, Tegtbur U, Fauck C, Fuhrmann F, Markewitz D, Salthammer T. (2010). Experimental setup and analytical methods for the non-invasive determination of volatile organic compounds