Serum BPA concentrations in diet-exposed mice the Challenge Phenol, 4,4’‑(1‑methylethylidene) bis‑ (Bisphenol A). Chemical Abstracts Service Registry Number 80‑05‑7. Available: http://www.ec.gc.ca/substances/ese/ eng/challenge/batch2/batch2_80‑ 05‑ 7.cfm [accessed 18 March 2011]. FDA (Food and Drug Administration). 2008. Food and Drug Administration Draft Assessment of Bisphenol A for Use in Food Contact Applications, 14 August 2008. Available: http://www.fda.gov/ohrms/dockets/AC/08/briefing/2008‑ 0038b1_01_02_FDA%20BPA%20Draft%20Assessment.pdf [accessed 1 August 2011]. Food and Agriculture Organization of the United Nations and the World Health Organization. 2010. Joint FAO/WHO Expert Meeting to Review Toxicological and Health Aspects of Bisphenol A. Available: http://www.who.int/ foodsafety/chem/chemicals/bisphenol_release/en/index. html [accessed 1 August 2011]. Galloway T, Cipelli R, Guralnik J, Ferrucci L, Bandinelli S, Corsi AM, et al. 2010. Daily bisphenol A excretion and associations with sex hormone concentrations: results from the InCHIANTI adult population study. Environ Health Perspect 118:1603–1608. Gies A, Heinzow B, Dieter HH, Heindel J. 2009. Bisphenol A workshop of the German Federal Environment Agency— March 30–31, 2009: work group report: public health issues of bisphenol A. Int J Hyg Environ Health 212(6):693–696. Hanioka N, Takeda Y, Tanaka‑ Kagawa T, Hayashi K, Jinno H, Narimatsu S. 2008. Interaction of bisphenol A with human UDP‑glucuronosyltransferase 1A6 enzyme. Environ Toxicol 23(3):407–412. He Y, Miao M, Herrinton LJ, Wu C, Yuan W, Zhou Z, et al. 2009. Bisphenol A levels in blood and urine in a Chinese popula‑ tion and the personal factors affecting the levels. Environ Res 109(5):629–633. Inoue H, Tsuruta A, Kudo S, Ishii T, Fukushima Y, Iwano H, et al. 2005. Bisphenol A glucuronidation and excretion in liver of pregnant and nonpregnant female rats. Drug Metab Dispos 33(1):55–59. Institute of Laboratory Animal Resources 1996. Guide for the Care and Use of Laboratory Animals. 7th ed. Washington, DC: National Academy Press. Kavaliers M, Hirst M, Teskey GC. 1985. Nocturnal feeding in the mouse—opiate and pineal influences. Life Sci 36(10):973–980. Kurebayashi H, Betsui H, Ohno Y. 2003. Disposition of a low dose of 14C‑ bisphenol A in male rats and its main biliary excretion as BPA glucuronide. Toxicol Sci 73(1):17–25. Matsumoto A, Kunugita N, Kitagawa K, Isse T, Oyama T, Foureman GL, et al. 2003. Bisphenol A levels in human urine. Environ Health Perspect 111:101–104. Nepomnaschy PA, Baird DD, Weinberg CR, Hoppin JA, Longnecker MP, Wilcox AJ. 2009. Withinp‑erson variability in urinary bisphenol A concentrations: measurements from specimens after long‑term frozen storage. Environ Res 109(6):734–737. Padmanabhan V, Siefert K, Ransom S, Johnson T, Pinkerton J, Anderson L, et al. 2008. Maternal bisphenol‑A levels at delivery: a looming problem? J Perinatol 28(4):258–263. Pottenger LH, Domoradzki JY, Markham DA, Hansen SC, Cagen SZ, Waechter JM. 2000. The relative bioavailability and metabolism of bisphenol A in rats is dependent upon the route of administration. Toxicol Sci 54(1):3–18. Sakamoto H, Yokota H, Kibe R, Sayama Y, Yuasa A. 2002. Excretion of bisphenol A‑glucuronide into the small intes ‑ tine and deconjugation in the cecum of the rat. Biochim Biophys Acta 1573(2):171–176. Stahlhut RW, Welshons WV, Swan SH. 2009. Bisphenol A data in NHANES suggest longer than expected half‑life, substan ‑ tial non‑food exposure, or both. Environ Health Perspect 117:784–789. Tam YK. 1993. Individual variation in first‑pass metabolism. Clin Pharmacokinet 25(4):300–328. Taylor JA, Vom Saal FS, Welshons WV, Drury B, Rottinghaus G, Hunt PA, et al. 2011. Similarity of bisphenol A pharmaco‑ kinetics in rhesus monkeys and mice: relevance for human exposure. Environ Health Perspect 119:422–430. Teeguarden JG, Calafat AM, Ye X, Doerge DR, Churchwell MI, Gunawan R, et al. 2011. 24‑ Hour human urine and serum profiles of bisphenol A during high dietary exposure. Toxicol Sci doi:10.1093/toxsci/kfr160 [Online 24 June 2011]. Tominaga T, Negishi T, Hirooka H, Miyachi A, Inoue A, Hayasaka I, et al. 2006. Toxicokinetics of bisphenol A in rats, monkeys and chimpanzees by the LC‑MS /mS method. Toxicology 226(2–3):208–217. Vandenberg LN, Chahoud I, Heindel JJ, Padmanabhan V, Paumgartten FJ, Schoenfelder G. 2010a. Urinary, circu‑ lating, and tissue biomonitoring studies indicate wide‑ spread exposure to bisphenol A. Environ Health Perspect 118:1055–1070. Vandenberg LN, Chahoud I, Padmanabhan V, Paumgartten FJ, Schoenfelder G. 2010b. Biomonitoring studies should be used by regulatory agencies to assess human exposure levels and safety of bisphenol A. Environ Health Perspect 118:1051–1054. Vandenberg LN, Hauser R, Marcus M, Olea N, Welshons WV. 2007. Human exposure to bisphenol A (BPA). Reprod Toxicol 24(2):139–177. Vandenberg LN, Maffini MV, Sonnenschein C, Rubin BS, Soto AM. 2009. Bisphenol‑A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Rev 30(1):75–95. Volkel W, Colnot T, Csanady GA, Filser JG, Dekant W. 2002. Metabolism and kinetics of bisphenol A in humans at low doses following oral administration. Chem Res Toxicol 15(10):1281–1287. vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M, et al. 2007. Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol 24(2):131–138. Wilkinson GR. 1997. The effects of diet, aging and disease‑ states on presystemic elimination and oral drug bioavail‑ ability in humans. Adv Drug Deliv Rev 27(2–3):129–159. Willhite CC, Ball GL, McLellan CJ. 2008. Derivation of a bis‑ phenol A oral reference dose (RfD) and drinking‑water equivalent concentration. J Toxicol Environ Health B Crit Rev 11(2):69–146. Environmental Health Perspectives • volume 119 | number 9 | September 2011 1265