Karyotypic and fluorescent in-situ hybridization study of the centromere of chromosome 7 in secondary myeloid neoplasms neoplasias (n= 19), aplastic anemia (n= 11), solid tumors (n= 6), autoimmune diseases (n= 4) and solid organ transplantations (n=2). The treatments of the previous diseases are listed in Table 1. The median latency between the previous disease and secondary MN was 85.4 months (range: 23.8- 221.3 months). Rev Bras Hematol Hemoter. 2011;33(6):425-31 427