Journal of Proteome Research Table 3. Selected Up- and Down-regulated Genes and Proteins between S. acidocaldarius, S. solfataricus and S. tokodaii during Bioﬁlm Mode of Growtha fold change (log2) proteomic microarray functional group Energy production and conversion Cytochrome c oxidase polypeptide I Cytochrome b558/566, subunit A Cytochrome b Rieske iron sulfur protein (SoxL) Quinol oxidase-2, sulfocyanin (SoxE) V-type ATP synthase subunit B V-type ATPase, alpha subunit ATP synthase subunit E Acetyl-coenzyme A synthetase Lactate/malate dehydrogenase Succinyl- CoAsynthetase betasubunit NADP dependent glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate synthase Acyl-CoA dehydrogenase related protein (acd-like2) Carbon monoxide dehydrogenase subunit G Sulfurtransferase enoyl-CoA hydratase Carbon monoxide dehydrogenase large chain Oxidoreductase Thiosulfate reductase electron transport protein (PhsB) Pyridine nucleotide-disulﬁde oxidoreductase Formate dehydrogenase subunit alpha Indolepyruvate oxidoreductase, subunit A Anaerobic glycerol-3-phosphate dehydrogenase subunit C Diphosphomevalonate decarboxylase Dehydrogenase (ﬂavoprotein) 3-hydroxybutyryl-CoA Dehydrogenase Inorganic pyrophosphatase Anaerobic dimethylsulfoxide reductase Putative thiosulfate sulfurtransferase Sulfurtransferase enoyl-CoA hydratase Carbohydrate transport and metabolism Sugar-related transporter Sugar transporter proline/betaine transporter Maltose-binding protein Lipid transport and metabolism 3-oxoacyl-(acyl carrier protein) reductase (fabG-1) ORF Saci_0097 ST2595 SSO2801 ST0137 Saci_1860 SSO2972 Saci_1549 Saci_1548 SSO0563 ST1436 SSO0561 Saci_2062 ST1803 Saci_0246 ST0963 ST2477 Saci_1417 SSO2497 ST0085 SSO2430 ST0048 Saci_2117 SSO3009 SSO2794 ST1839 Saci_0331 ST0615 ST0081 ST0732 ST2369 Saci_1245 ST0977 Saci_0292 Saci_1109 SSO2390 ST1789 ST2564 ST0048 Saci_1782 SSO2057 Saci_2111 SSO2716 SSO2938 ST1103 Saci_1792 SSO0975 ST1299 4111 1.31 0.9 n.d n.s. 2.57 0.59 0.5 n.s. n.s. n.s. n.s. 0.94 0.76 n.s. n.d. n.s. n.s. 0.27 0.69 1.19 n.s. 0.51 0.3 0.32 0.67 n.s. n.s. n.s. n.s. n.s. n.s. n.d. n.s n.s. n.s. n.s. n.s. n.s. 0.59 0.93 0.71 0.66 0.31 n.s. 1.72 0.64 0.21 ARTICLE p-value microarray 0.006 0.017 0.001 0.034 0.006 0.025 0.044 0.051 0.075 0.029 0.002 0.046 0.021 0.022 0.381 0.023 0.006 0.012 0.056 0.003 0.012 0.032 n.d. n.s. 1.41 0.43 n.d. n.d. 0.35 0.55 1.03 0.47 1.01 n.d. n.s. 1.03 0.54 0.61 0.56 n.d. n.s. n.d. 2.01 n.s. n.d. n.d. n.d. 1.16 0.71 0.3 0.62 0.65 1.08 1.02 0.61 0.5 1.16 1.06 1.22 2.01 n.d. n.d. n.d. n.d. n.d. 0.44 n.d. n.d. n.d. dx.doi.org/10.1021/pr2003006 |J. Proteome Res. 2011, 10, 4105–4119