332 [5] [6] [7] [8] [9] M. Jenny et al.: Crinum latifolium, a promising and highly effective treatment for BPH, health and life. The Journal of Health Ministry of Vietnam, 2002, N 207. Doan TN. Crinum latifolium in treatment of Benign Hypertrophy of prostate and cancers. Journal of Health and Life of Vietnamese Health Ministry, 2002, N 148. Tram NTN, Yanchev I, Zvetkova E, Dineva J, Katzarova E, Kostov G, Svilenov D, Ilieva I, Shalamanov P. Retarded growth of chemically induced with 20-methylcholanthrene tumours in rats under the action of cold-hot aqueous extracts (decoctions) from Vietnamese plant Crinum latifolium (L.). Exp Pathol Parasitol. 2001; 4: 9–12. Tram NTN, Zvetkova E, Nikolova E, Katzarova E, Kostov G, Yanchev I, Baicheva O. A novel in vitro and in vivo T-lymphocyte activating factor in Crinum latifolium (L.) aqueous extracts. Exp Pathol Parasitol. 1999; 3: 21–26. Zvetkova E, Wirleitner B, Tram NTN, Schennach H, Fuchs D. Aqueous extracts of Crinum latifolium (L.) and Camellia sinensis show immunomodulatory properties in human peripheral blood mononuclear cells. Int Immunopharmacol. 2001; 1: 2143–2150. doi:10.1016/S1567-5769(01)00140-0 [10] Nathan CF. Peroxide and pteridine: a hypothesis on the regulation of macrophage antimicrobial activity by interferon gamma. Interferon. 1986; 7: 125–143. PMid:3102389 [11] Wirleitner B, Neurauter G, Schroecksnadel K, Frick B, Fuchs D. Interferon-γ-induced conversion of tryptophan: immunologic and neuropsychiatric aspects. Curr Med Chem. 2003; 10: 1581–1591. PMid:12871129 [12] Fuchs D, Hausen A, Reibnegger G, Werner ER, Dierich MP, Wachter H. Neopterin as a marker for activated cell-mediated immunity: application in HIV infection. Immunol Today. 1988; 9: 150–155. PMid:3076770 [13] Pfefferkorn ER, Eckel M, Rebhun S. Interferon-gamma suppresses the growth of Toxoplasma gondii in human fibroblasts through starvation for tryptophan. Mol Biochem Parasitol. 1986; 20: 215–224. PMid:3093859 [14] Ozaki Y, Edelstein MP, Duch DS. Induction of indoleamine 2,3-dioxygenase: a mechanism of the antitumor activity of interferon-gamma. Proc Natl Acad Sci U S A. 1988; 85: 1242–1246. PMid:3124115 [15] Munn DH, Shafizadeh E, Attwoodn JT, Bondarev I, Pashinem A, Mellor AL. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med. 1999; 189: 1363–1372. PMid:10224276 [16] Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J Exp Med. 2002; 196: 459–468. PMid:12186838 Sci Pharm. 2011; 79: 323–335