Won-Suk Lee, et al. Table 1. Demographic Data and Outcomes for Patients with Splenic Abscess No Gender / age No of abscess Microbiological etiology Leukocyte count, mm3 Size, cm 4 3 - - 4 5 7 5 4 10 - - - Predisposing factors DM/steroid Single Dental abscess Single Alcoholic Multifocal CHF/DM/HTN Multifocal Pancreatitis Single NHL Single Infective endocarditis Single Pancreatitis Single DM Single Aortic Stenosis Single AML Multifocal Angina Multifocal AML Multifocal 1 F / 70 E.coli 8,800 Splenectomy Recovered 2 M / 65 Streptococcus viridians 28,200 Antibiotics Recovered 3 M / 34 Negative 11,680 Antibiotics Recovered 4 M / 61 Negative 13,350 Splenectomy Recovered 5 M / 39 Actinomycosis 20,490 Antibiotics Recovered 6 M / 69 Negative 22,700 Splenectomy Expired 7 F / 67 Streptococcus viridians 5,590 PCD Recovered 8 M / 47 Negative 10,630 Antibiotics Recovered 9 M / 69 Klebsiella pneumoniae 8,548 Splenectomy Recovered 10 F / 71 Streptococcus viridians 13,200 Antibiotics Recovered 11 M / 21 Negative 2,960 Antibiotics Recovered 12 M / 70 Streptococcus viridians 28,920 Antibiotics Recovered 13 M / 49 Negative 770 Splenectomy Recovered Splenect/ 14 F / 62 HTN Multifocal 16 Klebsiella pneumoniae 10,770 Recovered nephrectomy 15 M / 76 Stomach cancer/DVT Single 8 Klebsiella pneumoniae 13,710 PCD Expired 16 M / 40 Pancreatitis Single 3 Negative 18,310 Antibiotics Recovered 17 M / 54 Stomach cancer Single 8 Klebsiella pneumoniae 4,220 PCD Expired 18 M / 67 Infective endocarditis Single 5 Streptococcus viridians 16,500 PCD Recovered DM, diabetes Mellitus; CHF, congestive heart failure; HTN, hypertension; NHL, non-Hodgkin’s lymphoma; AML, acute myelocytic leukemia; DVT, deep vein thrombosis; PCD, percutaneous drainage. Treatment Outcome Table 2. Comparison of the Three Treatment Modalities Treatment modality Antibiotics Percutaneous drainage Splenectomy s, single abscess; m, multiple abscesses. n 8 4 6 Table 3. Results from Series Evaluating Splenic Abscess in Different Countries Lead author Year published Llenas-García, et al.18 2009 Ferraioli, et al.23 2009 Thanos, et al.13 2002 Westh, et al.24 1990 Chang, et al.4 2006 Tung, et al.14 2006 Current series - n, number; GNB, gram-negative bacteria. Country Spain Italy US Denmark China Taiwan Korea n 22 16 11 20 67 51 18 Mean age 48.4 66.0 63.3 Dates of the study 1998 - 2006 1979 - 2005 1997 - 2000 1982 - 1987 1984 - 2004 1998 - 2003 1993 - 2008 Abscess (s / m) 4 / 4 4 / 0 3 / 3 Most common microbiological etiology M. Tuberculodis GNB GNB - K. pneumoniae K. pneumoniae S. viridans scesses was 12 cm (range: 3-16), while the average size of multiple abscesses was 3.7 cm (range: 2-5.5)(Fig. 2) DISCUSSION Splenic abscess is an uncommon entity. The incidence of splenic absess in various autopsy series has been estimated to be between 0.2% and 0.7%.15 The rare occurrence of splenic abscess is further evidenced by the fact that no splen- ic abscess was reported in a review of 540 intraabdominal abscesses.5 However, this uncommon disease is recently being reported more frequently. Two main contributing fac- tors to the apparent increase in the incidence of splenic ab- 290 Yonsei Med J http://www.eymj.org Volume 52 Number 2 March 2011