710 B. K. Nanjwade et al.: Drug in oil Gastric lipase antral contraction Emulsification in stomach SEDDS in triglycerides Drug in SEDDS containing glycerides Intestinal pancreatic lipase Lipid digestion (Lipolysis) Yields Monoglycerides and fatty acids Micellar solubilisation of lipolytic products by bile salts Micellar diffusion across the aqueous boundary layer Microclimate adjacent to intestinal membrane Uptake into enterocytes Sci Pharm. 2011; 79: 705–727 Fig. 2. Schematic diagram of the fate of lipids in the gut. SEDDS in monoglyceride