598 Current Genomics, 2010, Vol. 11, No. 8 (Table 1). Contd….. Gene SNP Chr. Loc. SNP Location Disease/Phenotype pValue Study Population N Refs. IL1RL1 / IL18R1 IL1RL1 / IL18R1 rs12999364 102974129 intergenic BHR / asthma 0.016 / 0.021 IL18R1 rs2287037 (C-69T) 102979028 5' near-gene Coal workers' pneumoco- niosis NS Candidate gene study IL1RL1 rs1861246 102966783 intronic BHR / asthma / Total IgE IL1RL1 rs1861245 102966906 intronic Asthma 0.032 0.021 / 0.05 / Candidate gene 0.02 study Candidate gene study IL1RL1 rs4988957 102968075 cod.syn Chronic rhinosinusitis 0.03 IL1RL1 rs10204137 102968212 Cod.non.syn Chronic rhinosinusitis 0.04 IL1RL1 rs10204137 102968212 Cod.non.syn Childhood asthma 0.013 IL1RL1 rs10192157 102968356 Cod.non.syn Childhood asthma 0.013 IL1RL1 rs10206753 102968362 Cod.non.syn Childhood asthma 0.013 Akhabir and Sandford Dutch French- Canadian founder population Reijmer- ink et al. - J Al- lergy Clin 175 / 163 / Immunol 230 families 2008 Bossé et al. - Respir 101 families Res 2009 Castano et al. - Am J Rhinol Allergy 2009 Castano et al. - Am J Rhinol Allergy 2009 Amund- sen et al. - Genes Immun 2010 Reijmer- ink et al. - J Al- lergy Clin Immunol 2008 Mexican Mexican Mexican Wu et al. - J Al- lergy Clin 492 cases + Immunol both parents 2010 Wu et al. - J Al- lergy Clin 492 cases + Immunol both parents 2010 Wu et al. - J Al- lergy Clin 492 cases + Immunol both parents 2010 Dutch French 198 / 185 families Nadif et al. - Eur 200 individu- Respir J als 2006 rs13015714 102971865 intergenic Coeliac disease NS Candidate gene study_follow-up to GWAS European (Swedish, Norwegian) 325 families Candidate gene study French- Canadian 206 cases / 196 controls Candidate gene study French- Canadian 206 cases / 196 controls Candidate gene study_follow-up to GWAS Candidate gene study_follow-up to GWAS Candidate gene study_follow-up to GWAS Candidate gene study