Etoz, Demirbas, Bulbul, Akay which had grown in size in the last few months. follow-up period, there were no complaints or re- Clinical examination revealed a red-bluish nodule, currences. sessile lesion located on the anterior mandibular alveolar crest (Figure 6). The lesion measured DISCUSSION 1x0.5 cm in size and had no ulcerated surface. Peripheral giant cell granuloma (PGCG) is a Radiological exploration showed no evidence of benign hyperplastic reactive lesion which is a bony involvement. The lesion was resected and relatively uncommon lesion of the oral mucosa. the wound was closed with a mucosal graft. Post- PGCG originates from the periodontal ligament operative healing was uneventful (Figure 7). Histo- or mucoperiosteum and is usually caused by lo- pathological examination confirmed the diagnosis cal irritation or chronic trauma. The etiology of of PGCG (Figures 8 and 9). Through the one-year PGCG is unknown. Local irritation factors such as Figure 4. Clinical view of the postoperative healing of the second patient. Figure 5. Histopathological view of the lesion of the second patient (A- hematoxylin eosin X40). Figure 6. Clinical view of the lesion of the third patient. Figure 7. Clinical view of the postoperative healing of the third patient. Figure 8. Histopathological view of the lesion of the third patient (hematoxylin eosin X40). Figure 9. Histopathological view of the lesion of the third patient (hematoxylin eosin X200). July 2010 - Vol.4 331 European Journal of Dentistry