D1272 Nucleic Acids Research, 2012, Vol. 40, Database issue Figure 1. Example Gene-centric page for PhoQ product(s). (A) Overall page, showing the structure of coliWiki pages with tables (red arrows), ﬁgures, jmol viewer (blue arrow) and text notes (yellow arrows). (B–E) Show expanded views of page areas. (B) Simulated tabs for navigation between pages related to PhoQ, and links to page sections. (C) User-editable table for GO annotations for PhoQ. This table is periodically repopulated with annotations from EcoCyc. (D) Domains and motifs table and associated ﬁgures. The motifs diagram is generated from the content of the domains table to its left, and from the alleles and phenotypes table on the PhoQ:Gene page. The TMHMM (24) diagram is automatically generated for all genes. (E) References and categories. References are automatically generated from a software extension that recog- nizes PMIDs in the tables and embedded via markup in the text notes sections. The Gene Product(s) page includes information about the protein or RNA. A major focus of EcoliWiki is the table for functional annotation using the Gene Ontology (GO) (26). This table allows users to add and correct GO annotations that we share with EcoCyc (8) and regular- ly deposit with the GO consortium (Figure 2). The Gene Product(s) page also includes sections for physical inter- actions, domains and motifs, structures, physical