Korean J Ophthalmol Vol.26, No.2, 2012 was a gross delay in implicit time in both eyes with 30 Hz f licker. Fundus f luorescein angiography (FFA) revealed window defects corresponding to areas of atrophy of the retinal pigment epithelium (RPE). The patient underwent laser photocoagulation to the lattice in his left eye. The patient returned for a follow-up visit 18 months later. His visual acuity was stable. Cataract formation was noted in his right eye. He had developed a bicycle wheel pattern of foveal schisis in his left eye. Imaging with spectral do- main optical coherence tomography (SD-OCT; Coperni- cus, Optopol Technologies, Zawierci, Poland) of the right eye revealed lamellar macular holes with macular schisis, microcystic spaces, and vitreo-macular traction. SD-OCT imaging of the left eye revealed cystoid macular edema with inner layer schisis. Foveal thickness was 77 microns in the right eye and 672 microns in the left eye. Micro- perimetry (Nidek Technologies, Padova, Italy) showed a reduced mean retinal sensitivity of 0.0 db in the right eye and 5.5 db in the left eye, with a central dense scotoma in both eyes (Fig. 1). Pedigree construction and venous blood sampling was done for cytogenetic analysis. The chromosomes were stained by Giemsa-trypsin banding and scanned using IKAROS sof tware (MetaSystems, Altltussheim, Ger- many). The pedigree showed an autosomal recessive in- heritance pattern with one additional affected male in the family. Twenty-five plates, which were screened for the proband, revealed normal karyotypes. However, genetic analysis could not be performed. A 144 Case 2 A 41-year-old male presented with decreased vision, haloes, and visual distortion that he had been experienc- ing for the past 13 years. His brother (case 3) was known to have the same problems. The patient’s best corrected visual acuity, with +0.50 DS / -4.50 DC ×100, was 6 / 36 in the right eye, and, with +0.50 DS / -4.00 DC ×80, was 6 / 15 in the left eye. Anterior segment examination was nor- mal. Indirect ophthalmoscopy revealed vitreous f loaters, macular schisis, and diffuse RPE alterations in both eyes. Also revealed was a peripheral hole in the inferotemporal quadrant in the left eye. The patient’s color vision was analyzed with the Farn- sworth D-15 test [6]. The total error score for the Farn- sworth test was 36 in the right eye and 19 in the left eye. The test results revealed tritanomaly in the right eye and diffuse color defect in the left eye. SD-OCT imaging of both eyes showed incomplete posterior vitreous detach- ment, elevated foveal contours, and foveal schisis. It also showed alteration of the photoreceptor layer. Foveal thick- ness was 292 microns in the right eye and 490 microns in the left eye. Microperimetry showed a reduced mean reti- nal sensitivity of 7.7 db in the right eye and 8.2 db in the left eye, with a central dense scotoma in both eyes (Fig. 2). Case 3 A 36-year-old male presented with decreased vision, haloes, and visual distortion that he had been experienc- B Fig. 1. (A) Fundus of the right eye shows lamellar macular holes with microcystic spaces and clumping of retinal pigment epithelium. Microperimetry shows grossly reduced retinal sensitivity. At the time of examination, time domain (Stratus) optical coherence tomogra- phy (OCT) showed confluent macular cystoid changes and foveal retinoschisis. Spectral domain OCT (SD-OCT) on the patient’s follow- up visit revealed lamellar macular holes with macular schisis, microcystic spaces, and vitreomacular traction. (B) The left eye fundus shows a bicycle wheel pattern of foveal schisis. Microperimetry shows dense central scotomas. Images from time domain OCT and SD- OCT show cystic maculopathy with foveal schisis. SD-OCT images were taken at the time of the follow-up visit revealed cystoid macular oedema with inner layer schisis.