356 JY Choi, et al. • Neuro-Behçet disease presented diplopia with hemiparesis of NBD but an unusual finding in MS. The lack of pulmonary neurologic onset before any other symptom of BD was seen in 3% of abnormalities and the MRI findings also support the exclusion of the cases. Concomitant manifestation of neurologic symptoms with neurosarcoidosis. The differentiation of MRI findings in NBD from other symptoms of BD was seen in 7.5% of all patients. those found in MS and neurosarcoidosis is based on predilection for different regions. Kocer et al.7) reported that the most commonly NBD has a remarkable impact on the quality of life and needs to be treated as early as possible. However, because of the insidious affected regions of the NBD were the mesodiencephalic area (46%), nature of the disease, BD is hardly to be diagnosed until it is fully the pontobulbar region (40%), and the hypothalamic-thalamic region developed. Therefore, specific diagnostic criteria for childhood BD should (23%). On the other hand, the lesions seen in MS affect predominantly be established through the consortium of the cases of BD. The brain the periventricular area and corpus callosum8). And there is predilection for hypothalamus, pituitary gland, leptomeninges, and cranial nerves in neurosarcoidosis9). The MRI image of our patient was compatible with the characteristic of adult NBD. MRI was indispensable for establishing diagnosis and follow-up. In conclusion, we should consider the possibility of NBD as the cause of neurologic manifestations developed by minor head trauma in patients who have no alternative diagnosis. In addition we have to The patient had no symptoms of fever, neck stiffness or viral fully evaluate the evidence of BD if someone has typical features of illness. And the vasculitis outside the brain was absent. Fujikawa and NBD on the brain MRI with neurological abnormalities. Suemitsu10) described the clinical characteristics of BD in children based on a retrospective study of patients with BD. They reported that entero-BD was more frequent in children than adults, while ocular complication and NBD were less frequent. The frequency of HLA-B51 was lower (14.4%) in children than adults. Four among 31 Japanese children with BD had developed NBD. The age of onset was variable (from 10 months to 13 years), and they had various type of NBD, such as transverse myelitis, meningitis, encephalitis, and convulsions. Fujikawa and Suemitsu10) suggested periodontitis, recurrent tonsilitis and rubella were estimated to be inducing factors for the onset of disease. Our patient had a history of minor head trauma. Jones et al.11) suggested a causal relationship between CNS trauma and the onset of autoimmune pathology in genetically susceptible animals by explaining the overwhelming increase in the Th1:Th2 cytokines ratios in mice with traumatic injury. Hirohata et al.12) demonstrated that CNS inflammation play a critical role in the pathogenesis of progressive neuropychiatric manifestations of BD by the elevated CSF level of interleukin-6. An international collaboratory study has also reported that patients who did not fulfill the international criteria of BD had significantly less frequencies of genital aphthosis, skin lesions hypersensitivity, or uveitis and more frequent neurologic manifestations13). In 33% of children who did not fulfill the international criteria of BD had neurologic symptoms, such as benign intracranial hypertension, hemiparesis, encephalopathy, brainstem syndrome, meningitis and cerebellar syndrome while 15% of children with BD had neurologic symptoms. We described the clinical course of a 9-year-old patient who do not fulfill the diagnostic criteria for BD, but show the typical features of NBD. Hentati et al suggested terms 'probable neuro-Behçet’ and ‘possible neuro-Behçet’ for such cases14). 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