Hala M. Koura, Nagwa Abdallah Ismail, Ashraf F. Kamel, Azza M. Ahmed, Amal Saad-Hussein, Laila K. Effat Table III. Growth and Phe comparison at baseline and follow-up study Table IV. Bone mineral status at baseline and follow-up study Weight_2007 Weight_2009 Height_2007 Height_2009 BMI_2007 BMI_2009 BMI_percentile_CDC_2007 BMI_percentile_CDC_2009 Egyptian BMI percentile 2007 Egyptian BMI percentile 2009 WAZ 2007 WAZ 2009 HAZ 2007 HAZ 2009 Phe [mg/dl] 2007 Phe [mg/dl] 2009 *Wilcoxon signed ranks test (Z-test) FN_BMD 2007 FN_BMD 2009 FN_BMC 2007 FN_BMC 2009 FN_Z-score_2007 FN_Z-score_2009 BMD_L2_L4_2007 BMD_L2_L4_2009 BMC_L2_L4_2007 BMC_L2_L4_2009 Z-score_L2_L4_2007 Z-score_L2_L4_2009 N 32 32 32 32 32 32 32 32 32 32 32 32 32 32 32 32 N 32 32 32 32 32 32 32 32 32 32 32 32 Mean 28.2 35.5 121.8 132.5 17.8 19.2 59.2 70.3 51.8 62 –0.29 1.12 –0.95 0.18 12.3 11.7 Mean 0.6 0.7 2.0 2.4 –0.7 –0.5 0.5 0.6 14.9 19.1 –0.4 –0.2 SD 2.43 2.67 4.20 3.91 2.75 3.06 5.20 4.58 5.13 4.17 0.22 0.57 2 0.65 0.95 0.98 SD 0.03 0.02 0.18 0.19 0.12 0.10 0.03 0.03 1.65 1.82 0.12 0.10 Paired t-test 11.653 Value of p < 0.0001 14.337 5.443 2.797 2.479 3.116 1.306* 0.8 8.97 5.048 2.777 9.959 9.312 1.378 Paired t-test < 0.0001 < 0.0001 < 0.01 < 0.05 < 0.005 NS NS Value of p < 0.0001 < 0.0001 < 0.01 < 0.0001 < 0.0001 NS 2009 (r = –0.4, p ≤ 0.05). No correlation was found between the duration of dietary compliance and lumbar and femoral BMD and its Z-scores in both evaluations. The individual progression of the femora and lumbar Z-scores on both occasions is shown in Figures 1 and 2 and Table V. It can be seen that femoral BMD Z-score declined in 9/32 patients (28%); 4/9 were off diet, 3/9 were irregularly compliant and 2/9 were strictly diet adherent; for the lumbar area 11/32 patients (34.37%) had a decreased lumbar Z-score; 4/11 were off diet, 3/11 strictly diet adherent, and 4/11 were irregularly compliant. At baseline, femoral osteopenia was present in 10 patients (31.25%) and 3/10 had osteopenia of the lumbar area as well; 5/10 were under the age of 7 years, and the other 5/10 aged from 9 to 16 years. Five (5/10) patients were on a strict diet, 3/10 were off diet, and 2/10 were irregularly compliant. At follow-up, improvement with an increase in Z-score was present in all 10 patients. Another 2 patients (6.25%), 19 and 21 years old, were not osteopenic at the start of the study but developed osteopenia (–1.11 and –1.8) at the end of the study. Among the osteopenic patients 5/10 were given oral drug supplement (calcium + vitamin D3) in 496 Arch Med Sci 3, June / 2011