D592 Nucleic Acids Research, 2009, Vol. 37, Database issue of Biochemistry and Molecular Biology on the Nomenclature and Classifcation of Enzymes. Academic Press, New York, NY. 6. Boutet,E., Lieberherr,D., Tognolli,M., Schneider,M. and Bairoch,A. (2007) UniProtKB/Swiss-Prot: the manually annotated section of the UniProt knowledgeBase. Methods Mol. Biol., 406, 89–112. 7. Wheeler,D.L., Barrett,T., Benson,D.A., Bryant,S.H., Canese,K., Chetvernin,V., Church,D.M., Dicuccio,M., Edgar,R., Federhen,S. et al. (2008) Database resources of the national center for biotechnology information. Nucleic Acids Res., 36, D13–D21. 8. Gene Ontology Consortium. (2008) The Gene Ontology project in 2008. Nucleic Acids Res., 36, D440–D444.