Baseline Post-baseline Moxifloxacin Baseline Post-baseline Comparators Data are based on patients where ECGs were recorded at baseline and post baseline for PO; Day 1 and Day 3 for IV/PO CAP and cSSSI. The shaded box indicates the inter-quartile range (IQR). The drawn from the upper edge of the box extends to the largest observed QTcB value within the upper fence (located at 1.5 IQR above the upper quartile; the fences are not displayed in the graph) and from the lower edge of the box extends to the smallest observed QTcB value within the lower fence (located at 1.5 IQR below the lower quartile). * = mean; x = observations outside the upper/lower fence; horizontal bar = median. IV/PO CAP 158 Current Drug Safety, 2012, Vol. 7, No. 2 Haverkamp et al. PO All Studies 600 550 500 450 ) s (m400 B c T Q350 300 250 600 550 500 450 ) s (m400 B c T Q350 300 250 600 550 500 450 ) s (m400 B c T Q350 300 250 Baseline Day 1 Day 3 Baseline Day 1 Day 3 Moxifloxacin Comparators The shaded box indicates the interquartile range (IQR). The drawn from the upper edge of the box extends to the largest observed QTcB value within the upper fence (located at 1.5 IQR above the upper quartile; the fences are not displayed in the graph) and from the lower edge of the box extends to the smallest observed QTcB value within the lower fence (located at 1.5 IQR below the lower quartile). * = mean, x = observations outside the upper/lower fence, horizontal bar = median. IV/PO cSSSI Baseline Day 1 Day 3 Baseline Day 1 Day 3 Moxifloxacin Comparators The shaded box indicates the interquartile range (IQR). The drawn from the upper edge of the box extends to the largest observed QTcB value within the upper fence (located at 1.5 IQR above the upper quartile; the fences are not displayed in the graph) and from the lower edge of the box extends to the smallest observed QTcB value within the lower fence (located at 1.5 IQR below the lower quartile). * = mean, x = observations outside the upper/lower fence, horizontal bar = median. For a list of comparator agents for each treatment group see Table 1. Fig. (2). Boxplots for QTcB Intervals in Randomized Active-Controlled Phase II to IV Studies where ECG was Recorded at Baseline and Post baseline (PO) and Baseline, Day 1 and Day 3 (IV/PO) of Treatment with Moxifloxacin or Comparators.