pISSN: 1011-8942 eISSN: 2092-9382 Korean J Ophthalmol 2011;25(5):352-354 http://dx.doi.org/10.3341/kjo.2011.25.5.352 Case Report Unilateral Peters’ Anomaly with Chorioretinal Coloboma in the Other Eye Dooyoung Cho, Donggyu Choi, Wooho Nam Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea An 18-year-old man presented with poor vision in both eyes that had been present since birth. Central corneal opacity and inferior peripheral sclerocornea with iridocorneal adhesion were observed upon anterior segment examination of the left eye. A coloboma of the iris was observed in the patient’s right eye, which manifested as a small notch in the inferior pupillary margin and cataract. Fundus examination of the right eye showed a large inferior chorioretinal coloboma involving the optic disc and macula. It is essential to examine the fundus in detail, if possible, in cases of Peters' anomaly, because these patients may have congenital anomalies such as chorioretinal coloboma. Key Words: Chorioretinal coloboma, Peters’anomaly, Retinal detachment right eye had an iris coloboma that manifested as a small notch in the inferior pupillary margin and cataract (Fig. 2). Fundus examination of the right eye showed a large inferior chorioretinal coloboma involving the optic disc and macula (Fig. 3). Staphyloma was observed in the right eye by B-scan ultrasonography (Fig. 4A). We did not detect any systemic malformations and there was no relevant family history. Discussion Since Peters’ original description in 1906 [3], many others have reported ocular abnormalities now known as Peters’ Peters' anomaly is characterized by central corneal opacity with defects in the corneal endothelium, Descemet's mem- brane, and posterior stroma. Variable degrees of iridolenticu- locorneal adhesions are often also present [1]. Peters' anomaly may be isolated or accompanied by other ocular malforma- tions such as chorioretinal coloboma, a congenital defect caused by faulty closure of the embryonic fissure, and asso- ciated with other ocular and systemic abnormalities [2]. Here, we describe a case of unilateral Peters’ anomaly in the left eye and chorioretinal coloboma in the right eye. Case Report An 18-year-old man presented with poor vision in both eyes that had been present since birth. On presentation, his visual acuity was 60 / 200 in the right eye and light percep- tion only in the left eye. The refractive error in the right eye was -11.0 diopters, and we were unable to measure the re- fractive error of the left eye because of sclerocornea. Intraocular pressure was 27 mmHg in the right eye and 21 mmHg in the left eye. Central corneal opacity and inferior peripheral sclerocornea with iridocorneal adhesion were ob- served in the anterior segment of the left eye (Fig. 1). The Received: July 13, 2010 Accepted: August 26, 2010 Reprint requests to Wooho Nam, MD. Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, #948-1 Daerim-dong, Yeongdeungpo-gu, Seoul 150-950, Korea. Tel: 82-2-829-5193, Fax: 82-2-848-4638, E-mail: wooho.nam@gmail.com Fig. 1. Central cornea. opacity and inferior peripheral sclerocornea with iridocorneal adhesion in the left eye. ⓒ 2011 The Korean Ophthalmological Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses /by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. 352