Screening tests Pap smear Negative Positive Cervicogram Negative Positive Histology Negative Positive Total Young Tae Kim, et al. Table 2. Outcome of Screening Tests and Histology No. of cases Percent (%) Result N ASC-US ASC-H LSIL HSIL SCC N1, N2 B1, B2 S1, S2 PL, PH, PC CNI CIN I CIN II CIN III CIS SCC 130 45 4 46 46 23 55 147 80 12 131 48 11 25 31 48 294 44.2 15.3 1.4 15.6 15.6 7.8 18.7 50.5 27.2 4.1 44.6 16.3 3.7 8.5 10.5 16.3 100.0 N, negative for intraepithelial lesion or malignancy; ASC-US, atypical squamous cells of undetermined significance; ASC-H, atypical squamous cells can not exclude HSIL; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; SCC, squamous cell carcinoma; CIN, cervical intraepithelial neoplasia. (4.1%). The histopathological diagnosis were cervicitis in 131 cases (44.6%), CIN I in 48 cases (16.3%), CIN II in 11 cases (3.7%), CIN III in 25 cases (8.5%), carcinoma in situ of cervix in 31 cases (10.5%), and invasive cervical carcinoma in 48cases (16.3%) (Table 2). The correlation of screening tests and histology Among 294 women, the Pap test was negative in 130 cases (44.2%) and positive in 164 cases (55.8%). The sensitivity of the Pap test was 72.0%, the specificity was 64.6%, the positive predictive value was 72.0%, the negative predictive value was 64.6%, the false positive rate was 28.0%, and the false negative rate was 35.4%. The instances of a positive result on the Pap test and negative in histology were 46 cases (15.6 %). The instances of Yonsei Med J Vol. 46, No. 2, 2005 a negative result on the Pap test and positive on the histology were 46 cases (15.6%). The cervico- graphies were negative in 202 cases (68.7%) and positive in 92 cases (31.3%). The sensitivity of cervicography was 39.6%, the specificity was 79.2%, the positive predictive value was 70.7%, the negative predictive value was 31.0%, the false positive rate was 29.3%, and the false negative rate was 49.0%. The instances of a positive result on cervicography and a negative result on his- tology were 27 cases (9.2%), and the instance of a negative result on cervicography and a positive result on histology were 99 cases (33.7%). 101 cases (34.4%) were normal by both tests, and 193 cases (65.6%) were positive by either of the two screening tests. When combining the two scre- ening tests, the sensitivity was 79.3%, the speci- ficity was 51.5%, the positive predictive value was