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Neuron 64: 173–187 The EMBO Journal is published by Nature Publishing Group on behalf of European Molecular Biology Organization. This work is licensed under a Creative Commons Attribution-Noncommercial- No Derivative Works 3.0 Unported License. [http://creative commons.org/licenses/by-nc-nd/3.0] 1704 The EMBO Journal VOL 30 | NO 9 | 2011 & 2011 European Molecular Biology Organization