CLINICS 2011;66(3):493-499 Silva JH et al. Figure 2 - Body mapping of a male patient, 34 years of age, 256 nevi selected for follow-up. Presents 3 criteria for AMS: more than 100 nevi, presence of more than 2 clinically dysplastic nevi and nevi on the buttocks. three are considered carriers of AMS phenotype1 (Figure 2). Other classifications have also been described, including the so-called Classical AMS which includes patients with over 100 nevi, at least one lesion with clinical features of an atypical nevus and one nevus 8 mm or more in its largest diameter.3,28 The classification devised by the National Institutes of Health (NIH) includes only those patients with a familial history of melanoma (Table 1).29 The Kraemer16 and Rigel15 classifications indicate the magnitude of the risk of melanoma for patients with AMS, which appears to be most dependent on a personal and / or family history of melanoma and for some cases a relative risk (RR) of 1269 has been reported3 (Figure 3). According to Kraemer et al.16, AMS patients can be classified into the following types according to their heredity characteristics: type A: sporadic AMS; type B: familial AMS; type C: sporadic AMS with personal history of melanoma; type D1: familial AMS, with one family member with a history of melanoma; type D2: familial AMS with two or more family members with a history of melanoma. The different disease types indicate various risks of developing cutaneous melanoma. Rigel et al.15,30 classified AMS patients into four risk groups according to the presence or absence of a personal Figure 3 - Kraemer and Rigel Classifications. 495