Gene Signature 64. Chen T, Turner J, McCarthy S, Scaltriti M, Bettuzzi S, et al. (2004) Clusterin Mediated Apoptosis is Regulated by APC and is P21 Dependent but P53 Independent. Cancer Res 64: 7412–19. 65. Montironi R, Mazzucchelli R, Scarpelli M, Lopez-Beltran A, Fellegara G, et al. (2005) Gleason Grading of prostate cancer in needle biopsies or prostatectomy specimens: contemporary approach, current clinical significance and sources of pathology discrepancies. BJU Int 95: 1146–52. PLoS ONE | www.plosone.org 9 October 2008 | Volume 3 | Issue 10 | e3617