Found at: doi:10.1371/journal.pgen.1000462.s008 (0.04 MB PDF) Table S1 Oligonucleotide sequences. Found at: doi:10.1371/journal.pgen.1000462.s009 (0.07 DOC) MB Table S2 p53 response elements used to build position weight matrix. Found at: doi:10.1371/journal.pgen.1000462.s010 (0.10 MB DOC) Acknowledgments We appreciate the support of the Intramural Research Program of the National Institute of Environmental Health Sciences, National Institutes of References 1. Espinosa JM (2008) Mechanisms of regulatory diversity within the p53 transcriptional network. Oncogene 27: 4013–4023. 2. Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, et al. (2003) Phosphorylation site interdependence of human p53 post-translational modifi- cations in response to stress. J Biol Chem 278: 37536–37544. 3. el-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B (1992) Definition of a consensus binding site for p53. Nature Genetics 1: 45–49. 4. 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