Inhibition of Tumor Angiogenesis by Phloroglucinol Figure 5. Effect of phloroglucinol on EPC mobilization in LLC tumor-bearing mice. (A) Schematic experimental schedule of in vivo EPC mobilization kinetics. After subcutaneous injection with 56106 LLC, the mice were orally administered DMSO vehicle (control) or 0.94 mg/kg phloroglucinol daily for 5 days after the initiation of therapy. Circulating MNCs were harvested at day 5 by Ficol-gradient centrifugation. (B) A PLoS ONE | www.plosone.org 7 April 2012 | Volume 7 | Issue 4 | e33618