Analysis of the Elephant Immunoglobulin Genes Figure 8. The six elephant germline JH gene segments. Nucleotide and deduced amino acid sequences of six JH segments, along with RSSs, are shown. The amino acid residue W is replaced by a stop codon in the JH1 segment. doi:10.1371/journal.pone.0016889.g008 Figure 9. The elephant IgL locus. The elephant Igk locus is distributed over three scaffolds (202, 50, and 86), and the Igl locus is located on scaffold 68. Overall configurations are drawn approximately to scale. The potentially functional Vk and Vl genes are shown as filled bars, while pseudogenes are represented by open bars and indicated with the letter p. Double slashes indicate gaps .10 kb. The unidirectional arrowheads below Vk gene segments on scaffold 86 indicate that their transcriptional direction is opposite to downstream Jk segments. However, the unidirectional arrowheads on scaffolds 202 and 50 do not represent different transcriptional directions from the identified Jk gene segment; they merely indicate a transcriptional direction different from that of the remaining Vk gene segments in the scaffold. doi:10.1371/journal.pone.0016889.g009 PLoS ONE | www.plosone.org 9 February 2011 | Volume 6 | Issue 2 | e16889