TGF-b Inhibition in Myeloma Figure 7. TGF-b inhibition suppresses MM cell growth in bone as well as bone destruction. INA6-bearing SCID-rab mice were given food containing either the TGF-beta type I receptor kinase inhibitor Ki26894 or a vehicle control. A. Mouse serum samples were collected 6 weeks after the PLoS ONE | www.plosone.org 12 March 2010 | Volume 5 | Issue 3 | e9870