Table 3. cont. Systolic BP 1 10 18.8 2 7 156.6 3 10 18.8 4 10 18.8 5 7 156.6 Diastolic BP 1 5 171.0 2 10 17.0 Fasting plasma glucose 1 10 50.2 Thyroid Stimulating Hormone 1 9 97.8 2 7 3.7 3 9 97.7 4 12 2.8 5 9 97.7 6 7 3.7 7 7 3.7 8 9 97.6 9 9 97.7 10 7 3.7 11 7 3.7 12 7 3.7 13 9 97.6 14 9 97.6 15 9 97.8 16 7 3.7 17 9 97.6 18 7 3.6 19 7 3.7 20 9 97.7 21 7 3.6 22 9 97.4 23 7 3.7 24 9 97.6 25 9 97.7 26 6 98.8 27 9 97.6 28 7 3.7 C-reactive protein 1 19 50.1 2 12 112.4 3 12 119.7 4 2 24.2 5 12 119.7 6 12 112.4 7 2 24.0 8 12 119.7 PLoS Genetics | www.plosgenetics.org rs7069923 rs2527866 rs4237348 rs4628581 rs2527865 rs254893 rs10508517 rs10745259 rs755109 rs6462411 rs10983893 rs10848704 rs4743136 rs10241703 rs6958535 rs925488 rs10983932 rs6959674 rs11514766 rs7804166 rs1877431 rs1588635 rs10984516 rs1962785 rs2805809 rs12531984 rs10243770 rs10119795 rs12539695 rs2805810 rs6956479 rs2668804 rs7036589 rs6909430 rs2808693 rs10245389 rs4420638 rs11066587 rs1039302 rs7561273 rs10437838 rs11066595 rs17711796 rs10431387 C C T A T A A T C C C C G T C G T C T C A A T C A G C C G T G A A G G C G G T A T G C G T A C C C G G C T T T T C C T A A T C T G C C G G A T T C C C C T A A T A C C G A C T A Rank Chr Position (Mb) SNP A1 A2 MAF P-value b Var expl Nearest Gene(s) GWAS on the Island of Kosrae 1.9E-05 0.19 1.5% c10orf71 0.49 0.23 0.50 0.49 0.23 0.06 0.43 0.29 0.23 0.20 0.15 0.35 0.25 0.20 0.20 0.19 0.15 0.20 0.20 0.20 0.19 0.19 0.13 0.20 0.18 0.20 0.18 0.27 0.19 0.16 0.20 0.18 0.14 0.08 0.18 0.20 0.21 0.16 0.36 0.32 0.35 0.16 0.35 0.36 1.1E-06 2.9E-06 3.1E-06 3.7E-06 3.8E-06 5.5E-06 6.1E-06 9.9E-07 1.3E-06 1.6E-06 1.7E-06 1.7E-06 2.1E-06 2.6E-06 2.6E-06 2.6E-06 3.2E-06 3.4E-06 3.4E-06 3.5E-06 3.9E-06 4.0E-06 4.2E-06 4.3E-06 4.5E-06 4.7E-06 4.9E-06 5.6E-06 5.7E-06 6.0E-06 6.1E-06 7.2E-06 8.1E-06 9.6E-06 9.9E-06 1.6E-06 4.5E-06 5.2E-06 6.1E-06 6.2E-06 6.8E-06 7.3E-06 8.0E-06 9 0.19 1.8% 20.27 2.5% 0.18 1.5% 0.18 1.5% 20.27 2.5% 20.58 4.1% 20.18 1.5% 20.31 3.3% 20.36 4.2% 20.31 2.4% 20.29 3.7% 20.29 3.0% 20.34 3.7% 20.34 3.7% 20.29 2.7% 20.31 2.4% 20.33 3.6% 20.34 3.7% 20.34 3.7% 20.29 2.7% 20.29 2.6% 20.33 2.4% 20.34 3.6% 20.28 2.3% 20.34 3.7% 20.37 4.0% 20.27 2.8% 20.34 3.6% 20.28 2.2% 20.34 3.7% 20.28 2.3% 20.30 2.2% 20.49 3.8% 20.28 2.3% 20.34 3.7% 20.28 2.6% 0.26 1.8% 0.21 2.0% 20.22 2.1% 0.21 2.0% 0.26 1.8% 20.22 2.2% 0.21 2.0% hemgn,c9orf156 sdk1 ensg00000118975,fkbp4 cacnb2 ube3c cacnb2 cacnb2 ube3c cubn sdk1 sdk1 sdk1 sdk1 sdk1 hemgn,anp32b sdk1 sdk1 sdk1 c9orf156 sdk1 tmod1 sdk1 c9orf156 ensg00000188515 sdk1 tomm40, apoc2, apoe, apoc4, apoc1 sppl3 ensg00000173957, ubxd4, fkbp1b, flj21945 sppl3 ensg00000163019 sppl3 February 2009 | Volume 5 | Issue 2 | e1000365