Supporting Information Table S1 Genes up-regulated in sik1flp/flp ES cells, FDR,5%. Found at: doi:10.1371/journal.pone.0009029.s001 (0.06 MB XLS) Table S2 Genes down-regulated in sik1flp/flp ES cells, FDR,5%. Found at: doi:10.1371/journal.pone.0009029.s002 (0.07 MB XLS) Table S3 Gene Ontology analysis on the gene-set transcription- ally affected in sik1flp/flp ES cells. Found at: doi:10.1371/journal.pone.0009029.s003 (0.04 MB DOC) Table S4 Detection of functional DNA binding sites on genes differentially expressed between wt and sik1flp/flp ES. Found at: doi:10.1371/journal.pone.0009029.s004 (0.02 MB XLS) References 1. Srivastava D, Olson EN (2000) A genetic blueprint for cardiac development. Nature 407: 221–226. 2. Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP (1993) Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119: 969. 3. 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PLoS ONE | www.plosone.org 12 February 2010 | Volume 5 | Issue 2 | e9029