Prion Disease Biomarker Figure 3. Urinary a1-ACT and creatinine levels. a1-ACT levels (mg/L) were plotted relative to creatinine levels (g/L) for (a) sCJD patients together with Control group A, AD, and Control group C patients and (b) vCJD patients together with respective Control group B patients. Error bars represent s.e.m. doi:10.1371/journal.pone.0003870.g003 PLoS ONE | www.plosone.org 6 December 2008 | Volume 3 | Issue 12 | e3870