Immunoglobulin Genomics in the Guinea Pig Figure 6. The alignment of deduced amino acid sequences of guinea pig 94 functional VH genes. The sequences of functional V genes were analyzed by Megalign software and BioEdit programe. The Designation of framework regions (FR) and complementarity determining regions (CDR) referred to IMGT numbering system, and the CDR region are indicated by grey-squared background. amino acid sequences that are the same as the top segment, VH1-75-54, are indicated with dots. Dashes mean gaps introduced to make the alignment. doi:10.1371/journal.pone.0039298.g006 PLoS ONE | www.plosone.org 6 June 2012 | Volume 7 | Issue 6 | e39298