Novel CCR2-RFP Mice in EAE Figure 1. Generation and characterization of CCR2RFP mice. (A) Recombinant targeting strategy. Hatched box represents region of CCR2 deleted by recombination. Triangles represent loxP sites. (B) Southern blot analysis of WT, Ccr2RFP/+ heterozygous, and Ccr2RFP/RFP homozygous PLoS ONE | www.plosone.org 3 October 2010 | Volume 5 | Issue 10 | e13693