GAT: Graph Analysis Toolbox for Brain Networks Figure 5. Changes in global network measures as a function of network density. Normalized clustering (top), normalized path length (middle), and small-world index (bottom) of both the ALL and CON networks. Both the networks follow a small-world organization, i.e. normalized clustering of greater than 1 and normalized path length of close to 1. doi:10.1371/journal.pone.0040709.g005 Figure 6. Between-group differences in global network mea- sures as a function of network density. The 95% confidence intervals and between-group differences in normalized clustering (top), normalized path length (middle) and small-world index (bottom). The + marker shows the difference between CON vs. ALL networks; the + signs falling out of the confidence intervals indicate the densities in which the difference is significant. The positive values indicate CON . ALL and negative values indicate CON , ALL. Relative to CON network, the small-world index in ALL network was significantly lower in various network densities. The AUC of the small-world index was also significantly lower in the ALL network. doi:10.1371/journal.pone.0040709.g006 PLoS ONE | www.plosone.org 9 July 2012 | Volume 7 | Issue 7 | e40709