Rrd1 Regulates Elongation of RNA Polymerase II Figure 3. rrd1D deletion affects RNAPII localization in response to rapamycin. (A) Linear correlation of RNAPII median enrichment of WT (x- axis) and rrd1D mutant (y-axis) under normal growth conditions (2RAP) (left panel) and rapamycin treated conditions (+RAP) (right panel). The trend line and the R2 value are displayed for each condition. (B) Mapping of RNAPII from WT cells (green line) and rrd1D mutant cells (red line) under normal growth conditions (full line) and rapamycin treated conditions (dotted line) on cluster W1–W6 from figure 2A. Mappings are sorted for unaffected genes (green) upregulated genes (red) and downregulated genes (blue). doi:10.1371/journal.pone.0023159.g003 PLoS ONE | www.plosone.org 5 August 2011 | Volume 6 | Issue 8 | e23159