Cat Orientation Plasticity 28. Kasamatsu T, Schmidt EK (1997) Continuous and direct infusion of drug solutions in the brain of awake animals: implementation, strengths and pitfalls. Brain Res Protocols 1: 57–69. 29. Olson CR, Freeman RD (1980) Profile of the sensitive period for monocular deprivation in kittens. Exp Brain Res 39: 17–21. 30. O’Hashi K, Miyashita M, Tanaka S (2007) Experience-dependent orientation plasticity in the visual cortex of rats exposed to a single orientation. Neurosci Res 58: 86–90. 31. Rauschecker JP (1991) Mechanisms of visual plasticity: Hebb synapses, NMDA receptors, and beyond. Physiol Rev 71: 587–615. 32. Buller AL, Monaghan DT (1997) Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes. Eur J Pharmacol 320: 87–94. 33. Fagiolini M, Katagiri H, Miyamoto H, Mori H, Grant SGN, et al. (2003) Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc Nat Acad Sci USA 100: 2854–2859. 34. Tran DH, Gong R, Tang S-J (2007) Differential roles of NR2A and NR2B subtypes in NMDA receptor-dependent protein synthesis in dendrites. Neuropharmacol 53: 252–256. 35. Mower GD, Chen L (2003) Laminar distribution of NMDA receptor subunit (NR1, NR2A, NR2B) expression during the critical period in cat visual cortex. Brain Res Mol Brain Res 119: 19–27. 36. Huang Y, Yasuda H, Sarihi A, Tsumoto T (2008) Roles of endocannabinoids in heterosynaptic long-term depression of excitatory synaptic transmission in visual cortex of young mice. J Neurosci 28: 7074–7083. 37. Liu C-H, Heynen AJ, Hussain Shuler MG, Bear MF (2008) Cannabinoid receptor blockade reveals parallel plasticity mechanisms in different layers of mouse visual cortex. Neuron 58: 340–345. 38. Creutzfeldt OD, Heggelund P (1975) Neural plasticity in visual cortex of adult cats after exposure to visual patterns. Sicence 188: 1025–127. 39. Dragoi V, Sharma J, Sur M (2000) Adaptation-induced plasticity of orientation tuning in adult visual cortex. Neuron 28: 287–298. 40. Godde B, Leonhardt R, Cords SM, Dinse HR (2002) Plasticity of orientation preference maps in the visual cortex of adult cats. Proc Nat Acad Sci USA 99: 6352–6357. 41. Fregnac Y, Shulz D, Thorpe S, Bienenstock E (1988) A cellular analogue of visual cortical plasticity. Nature 333: 367–370. 42. Ringach DL, Sapiro G, Shapley R (1997) A subspace reverse-correlation technique for the study of visual neurons. Vision Res 37: 2455–2464. 43. Tsunoda K, Yamane Y, Nishizaki M, Tanifuji M (2001) Complex objects are represented in macaque inferotemporal cortex by the combination of feature columns. Nature Neurosci 4: 832–838. 44. Movshon JA, Thompson ID, Tolhurst DJ (1978) Spatial and temporal contrast sensitivity of neurones in areas 17 and 18 of the cat’s visual cortex. J Physiol 283: 101–120. 45. Ohki K, Matsuda Y, Ajima A, Kim D-S, Tanaka S (2000) Arrangement of orientation pinwheel centers around area 17/18 transition zone in cat visual cortex. Cereb Cortex 10: 593–601. 46. Imamura K, Kasamatsu T, Shirokawa T, Ohashi T (1999) Restoration of ocular dominance plasticity mediated by adenosine 39,59-monophosphate in adult visual cortex. Proc R Soc Lond B Biol Sci 266: 1507–1516. PLoS ONE | www.plosone.org 10 April 2009 | Volume 4 | Issue 4 | e5380