cyp6a17 Is Required for TPB in Drosophila Figure 4. cyp6a17 knockdown in the neurons results in abnormal temperature preference behavior. (A–D) Effects of tissue-specific knockdown of cyp6a17 on TPB. cyp6a17 was knockdowned by RNAi in pan-neuronal cell by Elav-Gal4 (A), whole body except head c290-Gal4 (B), ellipsoid bodies by c232-Gal4 (EB-Gal4) (C) and pars intercerebralis by dilp2-Gal4 (PI-Gal4) (D). Temperature preference profile and avoidance index (AI) are shown. Black bars, AIHigh; gray bars, AILow. One asterisks, P,0.005 and two asterisks, P,0.001. doi:10.1371/journal.pone.0029800.g004 PLoS ONE | www.plosone.org 6 December 2011 | Volume 6 | Issue 12 | e29800