Myelin Induces Inflammation Figure 3. Expression of inflammatory mediators at transcriptional and translational levels in bone marrow-derived macrophages regulated by myelin. (A) Cytokines and chemokines in the cells detected by qRT-PCR. (B) Cytokines in the supernatants of cell culture detected by ELISA. Data were expressed as mean 6 SEM and similar results were obtained from three independent experiments. (n = 3. *P,0.05 vs. control; one way ANOVA with Dunnett’s post-test). doi:10.1371/journal.pone.0009380.g003 PLoS ONE | www.plosone.org 6 February 2010 | Volume 5 | Issue 2 | e9380