Granules Movement in NK Cells Figure 2. Rab27a mutant decreased straightness and displacement but increased length of LG tracking at the PM. The length (A and B), displacement (C and D), and straightness (E and F) of LG trajectories from Ashen (red) and CH3 mice (black) are compared using histograms and cumulative probability plots. The data is derived from granules that travel within 10 seconds. The relative occurrence of each type of movement for each indicated condition is summarized in a bar plot (G). The numbers of tracking events (n) are listed on the right. The data are representative of at least two independent experiments. doi:10.1371/journal.pone.0012870.g002 PLoS ONE | www.plosone.org 3 September 2010 | Volume 5 | Issue 9 | e12870