transcription and enhancing iron uptake. Other Fe-S proteins are potential targets. Found at: doi:10.1371/journal.pone.0010345.s006 (0.60 MB TIF) Table S1 Top predicted mir-210 targets using tumour data plus algorithms. Found at: doi:10.1371/journal.pone.0010345.s007 (0.05 MB DOC) Table S2 Multivariate analysis of ISCU expression and relapse free survival in the Oxford: breast cancer series [14] (N = 216). Found at: doi:10.1371/journal.pone.0010345.s008 (0.05 MB DOC) Table S3 Multivariate analysis of mRNA ISCU expression and disease-specific survival in the Uppsala breast cancer series published series [27] (N = 235). Found at: doi:10.1371/journal.pone.0010345.s009 (0.05 MB DOC) Table S4 Multivariate analysis of ISCU expression and relapse free survival in the Rotterdam series of lymph-node-negative primary breast cancer [26] (N = 286). References 1. Harris AL (2002) Hypoxia–a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38–47. 2. 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