Table 3. cont. Table 3. cont. miRNA Group ID C. elegans miRNA Sequence-related Drosophila miRNAs miRNA Group ID C. elegans miRNA Sequence-related Drosophila miRNAs MicroRNAs of Worms and Flies Full Sequence miR-269 miR-273 miR-356 miR-357 miR-358 miR-359 miR-785 miR-787 miR-790 miR-791 miR-793 cel-miR-269 cel-miR-273 cel-miR-356 cel-miR-357 cel-miR-358 cel-miR-359 cel-miR-785 cel-miR-787 cel-miR-790 cel-miR-791 cel-miR-793 miR-795 cel-miR-795 miR-796 miR-797 cel-miR-796 cel-miR-797 miR-1018 miR-1022 cel-miR-1018 cel-miR-1022 59 Sequence dme-miR-31b dme-miR-31a dme-miR-31b dme-miR-100 dme-miR-87 dme-miR-277 dme-miR-9c dme-miR-3 dme-miR-318 dme-miR-987 dme-miR-993 dme-miR-263b dme-miR-263b dme-let-7 dme-miR-977 dme-miR-984 dme-let-7 dme-miR-963 dme-miR-977 dme-miR-984 dme-let-7 dme-miR-963 dme-miR-977 dme-miR-984 dme-miR-1 dme-miR-2a dme-miR-2b dme-miR-2c dme-miR-6 dme-miR-11 dme-miR-13a dme-miR-13b dme-miR-308 dme-bantam dme-bantam dme-miR-306* miR-794 cel-miR-794 dme-miR-977 miR-244 cel-miR-244 miR-231 miR-232 miR-233 miR-234 miR-235 miR-236 miR-237 miR-238 miR-239a miR-239b miR-240 miR-241 miR-245 miR-247 miR-249 miR-250 miR-251 miR-252 miR-256 miR-259 miR-260 miR-266 miR-267 miR-268 cel-miR-231 cel-miR-232 cel-miR-233 cel-miR-234 cel-miR-235 cel-miR-236 cel-miR-237 cel-miR-238 cel-miR-239a cel-miR-239b cel-miR-240 cel-miR-241 cel-miR-245 cel-miR-247 cel-miR-249 cel-miR-250 cel-miR-251 cel-miR-252 cel-miR-256 cel-miR-259 cel-miR-260 cel-miR-266 cel-miR-267 cel-miR-268 59 Sequence dme-miR-263b dme-miR-993 dme-miR-277 dme-miR-87 dme-miR-137 dme-miR-92a dme-miR-92b dme-miR-310 dme-miR-311 dme-miR-312 dme-miR-313 dme-miR-8 dme-miR-125 dme-miR-305 dme-miR-305 dme-miR-305 dme-miR-193 dme-let-7 dme-miR-963 dme-miR-977 dme-miR-984 dme-miR-9a dme-miR-9b dme-miR-9c dme-miR-133 dme-miR-279 dme-miR-286 dme-miR-996 dme-miR-308 dme-miR-2a dme-miR-2b dme-miR-2c dme-miR-6 dme-miR-11 dme-miR-13a dme-miR-13b dme-miR-308 dme-miR-1002 dme-miR-1002 dme-miR-1 dme-miR-277 dme-miR-304 dme-miR-989 dme-miR-31a dme-miR-31b dme-miR-100 dme-miR-31a Full Sequence dme-miR-137 dme-miR-92a dme-miR-92b dme-miR-310 dme-miR-311 dme-miR-312 dme-miR-313 dme-miR-8 dme-miR-12 dme-miR-133 dme-miR-996 dme-miR-1007 dme-miR-252 dme-miR-1 87 C. elegans miRNAs are 59 related to 62 Drosophila miRNAs (sequence alignments shown in Dataset S7), whereas 31 C. elegans miRNAs have $70% overall similarity to 37 Drosophila miRNAs (Dataset S8). Group IDs correspond to C. elegans miRNAs with sequence-related miRNAs in Drosophila. Nematode-fly miRNAs with weaker identity (60–69.9%) over full sequence are listed in Dataset S9. doi:10.1371/journal.pone.0002818.t003 posted in previous works and in the miRBase page listing of sequence relationships among miRNA precursors. The two homology search approaches we used identify a substantially overlapping list, although clearly not all miRNAs fit both 59 end and overall similarity criteria. Of the 139 C. elegans miRNAs analyzed, 77 miRNAs exhibit high identity at the 59 end PLoS ONE | www.plosone.org 6 July 2008 | Volume 3 | Issue 7 | e2818