Glutamate Receptors Editing Figure 7. Effects of pretreatment with celecoxib on KA-induced mRNA expression of NMDA receptor subunits in the hippocampus of wild type mice. Quantitative real time-PCR analysis of NR1 (A), NR2a (B), NR2b (C), NR2c (D), NR2d (E) NR3a (F), NR3b (G) in WT mice, after two weeks treatment with celecoxib, followed by an i.p. injection of KA or vehicle 24 hours later. Data are means 6 SEM (n = 9). Statistical analysis was performed using a one-way ANOVA and Bonferroni’s post-hoc test. *P,0.05, **P,0.01, ***P,0.001 compared to vehicle-injected WT mice; #P,0.05, ##P,0.01, ###P,0.001 compared to KA-injected WT mice. doi:10.1371/journal.pone.0019398.g007 PLoS ONE | www.plosone.org 11 May 2011 | Volume 6 | Issue 5 | e19398