NADPH Oxidase and Intermittent Hypoxia Figure 2. gp91phox_/Y mice exposed to IH do not exhibit any deficits in learning and memory functions. (A and B) Mean latencies (s) and pathlengths (cm) to locate the target platform during place training in C57BL6/J and gp91phox_/Y either exposed to intermittent hypoxia (IH) or maintained in room air (RA) (n = 12 per group. (C) Swim Speed (D) Mean percentage time in the target quadrant during probe trial after completion of water maze testing in either C57BL6/J and gp91phox_/Y exposed to IH or maintained in RA. (n = 12/experimental group; *P,0.05). doi:10.1371/journal.pone.0019847.g002 Figure 3. gp91phox_/Y mice exposed to IH do not exhibit any deficits in retention. (A) Mean latencies (s) and (B) pathlengths (cm) to locate the target platform during retention in C57BL6/J and gp91phox_/Y either exposed to intermittent hypoxia (IH) or maintained in room air (RA) during retention of the Morris water maze task. (n = 12/experimental group; *P,0.05). doi:10.1371/journal.pone.0019847.g003 PLoS ONE | www.plosone.org 4 May 2011 | Volume 6 | Issue 5 | e19847