Figure 1. The interaction and evolution of Sly and Slx/Slxl1. (A) A summary of the results from the various deficiency models generated by Cocquet et al. [7]. X and Y chromosome genotypes are given along the margin with wild-type genotypes in green and deficiency genotypes in red (shSLX and shSLY). Two transgenic constructs were made to target Slx/Slxl1 but are presented together here for clarity. For each genotype, the PLOS Genetics | www.plosgenetics.org 2 September 2012 | Volume 8 | Issue 9 | e1002955