LTP-Related Gene Networks Figure 5. IPA Categorization of LRG sets according to their Biological Functions. doi:10.1371/journal.pone.0040538.g005 SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4), a member of the CREST- BRG1 transcriptional coactivator complex [43], ROCK1, an activator of SRF [44] and CAMKI otherwise known as CREB kinase. Such molecular correlates of repression of gene expression are consistent with our observation that after the rapid LTP- induced increase in expression observed 20 min post-LTP (Figure 2; [13]) there is an attenuation of gene expression. The PLoS ONE | www.plosone.org 6 July 2012 | Volume 7 | Issue 7 | e40538