inducer of hemolysis, at doses of 60 mg/kg body weight for NOD/ shi-scid Jic mice and 80 mg/kg body weight for C57BL/6NCrj mice. The second induction of hemolysis shown in Figure 4B was performed at a dose of 80 mg/kg body weight in NOD/shi-scid Jic mice. Transplantation of cells Cells (26107 cells/mouse) were injected into the tail vein of an 8- week-old female mouse. Blood count Peripheral blood samples were obtained from the retro-orbital venous plexus. We estimated the number of white blood cells, red blood cells, and platelets, in addition to the hemoglobin concentration and hematocrit, using an automated Celltac a MEK-6358 counter (NIHON-KODEN, Tokyo, Japan). Statistical analysis All statistical analyses were performed using Statcel (OMS company, Saitama, Japan) analysis software. As for the two- sample t-test, the data were analyzed by the F test for variance followed by the Student’s t-test. 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