Drosophila Mitotic Genes Figure 2. RNAi phenotypes elicited by the genes detected in the screen (CS and CC phenoclusters). Colors refer to the strength of the phenotype: pale blue, weak; blue, strong. The numbers in the CAB column are frequencies of chromosome aberrations per cell. The other numbers refer to relatively rare phenotypic traits. PHC, phenocluster: CS, chromosome segregation; CC, chromosome condensation. Main phenotypic traits: NDC no dividing cells; CAB chromosome aberrations; ACC abnormal chromosome condensation; PCS precocious sister chromatid separation; DCC defective chromosome congression at metaphase; HCC hypercontracted chromosomes; LFA, low relative frequency of anaphases; DCS defective chromosome segregation following sister chromatid separation; NSS no sister chromatid separation with scattered chromosomes; NSC no sister chromatid separation with chromosomes at the center of the cell; CBA chromatin bridges at anaphase; DDA, chromosome decondensation during anatelophase; LTS long anatelophase spindles; MPS monopolar spindles; DSP defective spindle poles (defective asters and/or broad poles); SSP short spindles; LMD, spindles with low MT density; OSD other spindle defects; BIN binucleated cells (cytokinesis failure); OMD, other mitotic defects. Other phenotypic traits: (1) metaphase-like figures contain unreplicated chromosomes; (2) many anaphase-like figures but few telophase-like figures; (3) endoreduplicated metaphases (diplochromosomes); (4) lack of sister chromatid cohesion in the heterochromatic regions of the chromosomes. doi:10.1371/journal.pgen.1000126.g002 PLoS Genetics | www.plosgenetics.org 4 July 2008 | Volume 4 | Issue 7 | e1000126