de Godoy Journal of Medical Case Reports 2010, 4:295 http://www.jmedicalcasereports.com/content/4/1/295 As what I have described is a series of case reports, further controlled studies, including randomized double- blind controlled trials, which aim to reproduce the results and define the optimal time and efficacy rate of treatment are necessary. Conclusions Aminaphtone may be a novel option in the long-term treatment of stasis purpura when capillary fragility is identified. Consent This case series was approved by the local ethics com- mittee (protocol n04248/2009). Written informed con- sent was obtained from the patients for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Edi- tor-in-Chief of this journal. Competing interests The author declares that they have no competing interests. Received: 24 October 2009 Accepted: 31 August 2010 Published: 31 August 2010 References 1. Bergan J: Molecular mechanisms in chronic venous insufficiency. Ann Vasc Surg 2007, 21(3):260-266. 2. Worley CA: ’It hurts when I walk:’ venous stasis disease-differential diagnosis and treatment. Dermatol Nurs 2006, 18(6):582-583. 3. Barron GS, Jacob SE, Kirsner RS: Dermatologic complications of chronic venous disease: medical management and beyond. Ann Vasc Surg 2007, 21(5):652-662. 4. Kim D, Kang WH: Role of dermal melanocytes in cutaneous pigmentation of stasis dermatitis: a histopathological study of 20 cases. J Korean Med Sci 2002, 17(5):648-654. 5. Godoy JMP, Batigália F, Mendes RN, Paiva JV, Oliveira JD: Aminaftona no tratamento da epistaxe. Rev bras hematol hemoter 2003, 25(1):65-71. 6. Pereira de Godoy JM: Aminaphtone in idiopathic cyclic oedema syndrome. Phlebology 2008, 23(36):118-119. doi:10.1186/1752-1947-4-295 Cite this article as: de Godoy: Treatment of stasis dermatitis using aminaphtone: a case series. Journal of Medical Case Reports 2010 4:295. Page 3 of 3 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color ﬁgure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit