Kupert et al. BMC Cancer 2011, 11:513 http://www.biomedcentral.com/1471-2407/11/513 Author details 1Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA. 2Department of Pathology, University of Cincinnati College of Medicine, UC Metabolic Diseases Institute, 2120 E. Galbraith Road, Building A, Room 259, Cincinnati, OH 45237-0507, USA. 3Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA. 4Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA. 5Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA. Authors’ contributions EK, MA, KW, PC, SP, ZD, SS, and TM participated in patient specimens and data collection. JW and KW performed pathology analysis. PS and LL performed statistical analysis. YL carried out immunohistochemistry analysis and ELISA. 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