Lee et al. BMC Genomics 2011, 12:197 http://www.biomedcentral.com/1471-2164/12/197 Group of the International Committee on Taxonomy of Viruses. Arch Virol 1992, 123(3-4):425-449. 3. Ziemann K, Mettenleiter TC, Fuchs W: Gene arrangement within the unique long genome region of infectious laryngotracheitis virus is distinct from that of other alphaherpesviruses. J Virol 1998, 72(1):847-852. 4. Fuchs W, Mettenleiter TC: DNA sequence and transcriptional analysis of the UL1 to UL5 gene cluster of infectious laryngotracheitis virus. J Gen Virol 1996, 77(9):2221-2229. 5. Fuchs W, Mettenleiter TC: DNA sequence of the UL6 to UL20 genes of infectious laryngotracheitis virus and characterization of the UL10 gene product as a nonglycosylated and nonessential virion protein. J Gen Virol 1999, 80(8):2173-2182. 6. Griffin AM, Boursnell ME: Analysis of the nucleotide sequence of DNA from the region of the thymidine kinase gene of infectious laryngotracheitis virus; potential evolutionary relationships between the herpesvirus subfamilies. J Gen Virol 1990, 71(4):841-850. 7. Johnson MA, Prideaux CT, Kongsuwan K, Tyack SG, Sheppard M: ICP27 immediate early gene, glycoprotein K (gK) and DNA helicase homologues of infectious laryngotracheitis virus (gallid herpesvirus 1) SA-2 strain. Arch Virol 1995, 140(4):623-634. 8. Johnson MA, Tyack SG, Prideaux C, Kongsuwan K, Sheppard M: Nucleotide sequence of infectious laryngotracheitis virus (gallid herpesvirus 1) ICP4 gene. Virus Res 1995, 35(2):193-204. 9. Johnson MA, Tyack SG, Prideaux CT, Kongsuwan K, Sheppard M: Nucleotide sequence of the left-terminus of infectious laryngotracheitis virus (Gallid herpesvirus 1) SA-2 strain. Arch Virol 1997, 142(9):1903-1910. 10. Poulsen DJ, Burton CR, O’Brian JJ, Rabin SJ, Keeler CL Jr: Identification of the infectious laryngotracheitis virus glycoprotein gB gene by the polymerase chain reaction. Virus Genes 1991, 5(4):335-347. 11. Wild MA, Cook S, Cochran M: A genomic map of infectious laryngotracheitis virus and the sequence and organization of genes present in the unique short and flanking regions. Virus Genes 1996, 12(2):107-116. 12. Ziemann K, Mettenleiter TC, Fuchs W: Infectious laryngotracheitis herpesvirus expresses a related pair of unique nuclear proteins which are encoded by split genes located at the right end of the UL genome region. J Virol 1998, 72(8):6867-6874. 13. Thureen DR, Keeler CL Jr: Psittacid herpesvirus 1 and infectious laryngotracheitis virus: Comparative genome sequence analysis of two avian alphaherpesviruses. J Virol 2006, 80(16):7863-7872. 14. Smith DR, Quinlan AR, Peckham HE, Makowsky K, Tao W, Woolf B, Shen L, Donahue WF, Tusneem N, Stromberg MP, et al: Rapid whole-genome mutational profiling using next-generation sequencing technologies. Genome Res 2008, 18(10):1638-1642. 15. Deininger PL: Random subcloning of sonicated DNA: application to shotgun DNA sequence analysis. Anal Biochem 1983, 129(1):216-223. 16. Blacker H, Kirkpatrick N, Rubite A, O’Rourke D, Noormohammadi A: Epidemiology of recent outbreaks of infectious laryngotracheitis in poultry in Australia. Aust Vet J 2011, 89(3):89-94. 17. Cheng TP, Valentine MC, Gao J, Pingel JT, Yokoyama WM: Stability of murine cytomegalovirus genome after in vitro and in vivo passage. J Virol 2010, 84(5):2623-2628. 18. Sakaoka H, Kurita K, Iida Y, Takada S, Umene K, Kim YT, Ren CS, Nahmias AJ: Quantitative analysis of genomic polymorphism of herpes simplex virus type 1 strains from six countries: studies of molecular evolution and molecular epidemiology of the virus. J Gen Virol 1994, 75(3):513-527. 19. Devlin JM, Browning GF, Hartley CA, Kirkpatrick NC, Mahmoudian A, Noormohammadi AH, Gilkerson JR: Glycoprotein G is a virulence factor in infectious laryngotracheitis virus. J Gen Virol 2006, 87(10):2839-2847. 20. Fuchs W, Wiesner D, Veits J, Teifke JP, Mettenleiter TC: In vitro and in vivo relevance of infectious laryngotracheitis virus gJ proteins that are expressed from spliced and nonspliced mRNAs. J Virol 2005, 79(2):705-716. 21. Han MG, Kweon CH, Mo IP, Kim SJ: Pathogenicity and vaccine efficacy of a thymidine kinase gene deleted infectious laryngotracheitis virus expressing the green fluorescent protein gene. Arch Virol 2002, 147(5):1017-1031. 22. Pavlova SP, Veits J, Blohm U, Maresch C, Mettenleiter TC, Fuchs W: In vitro and in vivo characterization of glycoprotein C-deleted infectious laryngotracheitis virus. J Gen Virol 2010, 91(4):847-857. Page 6 of 6 23. Veits J, Luschow D, Kindermann K, Werner O, Teifke JP, Mettenleiter TC, Fuchs W: Deletion of the non-essential UL0 gene of infectious laryngotracheitis (ILT) virus leads to attenuation in chickens, and UL0 mutants expressing influenza virus haemagglutinin (H7) protect against ILT and fowl plague. J Gen Virol 2003, 84(12):3343-3352. 24. Zerbino DR, Birney E: Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res 2008, 18(5):821-829. 25. Drummond AJ, Ashton B, Cheung M, Heled J, Kearse M, Moir R, Stones- Havas S, Sturrock S, Thierer T, Wilson A: Geneious v5.0. 2010 [http://www. geneious.com/]. 26. Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, et al: Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23(21):2947-2948. doi:10.1186/1471-2164-12-197 Cite this article as: Lee et al.: First complete genome sequence of infectious laryngotracheitis virus. BMC Genomics 2011 12:197. Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color ﬁgure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit