BMC Public Health 2009, 9:300 http://www.biomedcentral.com/1471-2458/9/300 Table 2: Change in physicians' self-reported approach to the well-appearing young child with white blood cell count of 17,500/μL, with relation to PCV vaccination status Not Vaccinated child (n = 690) Vaccinated child (n = 690) Investigations (ordered at any time during febrile illness) Not Vaccinated child (n = 690) Vaccinated child (n = 690) Wait-and see (n;%) Empiric antibiotic therapy (n;%) Hospital admission (n;%) P (vaccinated vs. not-vaccinated child) ▪ Blood culture ▪ C reactive protein ▪ Erythrocyte sedimentation rate ▪ Urine analysis or dipstick ▪ Urine culture ▪ Stool culture ▪ Chest X ray ▪ Abdomen ultrasound scan ▪ Lumbar puncture ▪ Group A β haemolitic streptococcus rapid test Ceftriaxone i.m./i.v. Amoxicillin ± clavulanic acid Macrolide Per os cephalosporin Other No answer 8 (2.7) 267 (89.0) 5 (1.7) 8 (2.7) 1 (0.3) 11 (3.7) Note: i.m.: intramuscular; i.v.: intravenous 229 (33.2%) 381 (55.2%) 80 (11.6%) <0.0001 107 (15.5%) 468 (67.8%) 163 (23.6%) 428 (62.0%) 324 (47.0%) 12 (1.7%) 165 (23.9%) 56 (8.1%) 3 (0.5%) 7 (1.0%) 7 (2.8) 218 (86.9) 5 (2.0) 10 (4.0) 1 (0.4) 10 (4.0) 321 (46.5%) 337 (48.8%) 32 (4.7%) 77 (11.2%) 394 (57.1%) 126 (18.2%) 359 (52.0%) 311 (45.0%) 14 (2.0%) 139 (20.1) 41 (5.9%) 3 (0.5%) 6 (0.9%) 1 (0.7) 124 (89.2) 2 (1.4) 7 (5.0) 0 5 (3.6) P 0.022 <0.0001 0.017 0.028 0.501 0.843 0.104 0.140 0.682 1.000 Total N (%) 16 (2.3) 609 (88.3) 12 (1.7) 25 (3.6) 2 (0.3) 26 (3.8) Page 4 of 7 (page number not for citation purposes) Table 3: Physicians' self-reported preferred antibiotic for therapy empiric treatment. Primary care pediatricians n (%) Hospital pediatricians n (%) Pediatric residents n (%)