BMC Genomics 2008, 9:308 http://www.biomedcentral.com/1471-2164/9/308 88. Mah A, Perry G, Smith M, Monteiro M: Identification of ubiquilin, a novel presenilin interactor that increases presenilin pro- tein accumulation. J Cell Biol 2000, 151:847-62. 89. Tashiro M, Okubo S, Shimotakahara S, Hatanaka H, Yasuda H, Kain- osho M, Yokoyama S, Shindo H: NMR structure of ubiquitin-like domain in PARKIN: gene product of familial Parkinson's dis- ease. J Biomol NMR 2003, 25:153-6. 90. Cook W, Jeffrey L, Carson M, Chen Z, Pickart C: Structure of a diubiquitin conjugate and a model for interaction with ubiq- uitin conjugating enzyme (E2). J Biol Chem 1992, 267:16467-71. 91. Bateman A, Coin L, Durbin R, Finn RD, Hollich V, Griffiths-Jones S, Khanna A, Marshall M, Moxon S, Sonnhammer EL, Studholme DJ, Yeats C, Eddy SR: The Pfam protein families database. Nucleic Acids Res 2004, 32:D138-41. 92. Andrade MA, Ponting CP, Gibson TJ, Bork P: Protein repeats: structures, functions, and evolution. J Mol Biol 2000, 298:521-37. Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Page 11 of 11 (page number not for citation purposes)