Redaniel et al. BMC Cancer 2010, 10:100 http://www.biomedcentral.com/1471-2407/10/100 Table 3 Relative risk of death according to various prognostic factors among colorectal cancer patients, Philippine resident population and from Filipino-Americans and Non-Hispanic Whites from US SEER, 1993-2002, Bivariate analysis Variable Philippine resident population Filipino-Americans Non-Hispanic Whites 95% CI 0.82 - 1.09 0.79 - 1.22 0.84 - 1.27 0.86 - 1.34 1.34 - 2.37 1.20 - 1.83 2.90 - 4.80 0.78 - 1.31 2.21 - 3.21 0.82 - 1.31 RR 1.94 1.94 2.28 1.75 1.85 1.73 1.94 2.03 RR 1.00 0.85 1.00 0.85 1.18 1.53 3.15 1.00 1.77 7.96 1.00 0.63 1.00 5.46 1.00 1.03 95% CI 0.76 - 0.97 0.66 - 1.11 0.94 - 1.49 1.23 - 1.91 2.52 - 3.93 1.49 - 2.10 6.72 - 9.43 1.86 - 0.73 4.70 - 6.34 0.86 - 1.22 RR 1.00 1.00 1.00 1.04 1.28 1.75 3.08 1.00 1.56 6.95 1.00 0.72 1.00 5.19 1.00 1.15 95% CI 1.76 - 2.13 1.76 - 2.13 2.07 - 2.51 1.58 - 1.93 1.68 - 2.03 1.57 - 1.90 1.77 - 2.14 1.83 - 2.25 RR 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 95% CI — — — — — — — — RR 1.17 1.17 1.02 1.24 1.18 1.21 1.16 1.12 95% CI 1.10 - 1.24 1.10 - 1.24 0.96 - 1.09 1.16 - 1.32 1.11 - 1.25 1.14 - 1.28 1.10 - 1.24 1.04 - 1.20 Sex Male Female Age group <50 50-59 60-69 70-79 80+ Stage Localized Regional Distant Morphology Adenocarcinoma Others Surgery With surgery Without surgery Radiotherapy With radiotherapy Without radiotherapy RR 1.00 0.94 1.00 0.98 1.03 1.07 1.78 1.00 1.48 3.74 1.00 1.01 1.00 2.66 1.00 1.03 Bivariate analysis After controlling for other variables (one at a time) Sex Age Stage Morphology Surgery Radiotherapy Multivariate analysis1 RR, Relative Risk; 95% CI, 95% Confidence Interval 1Controlling for all variables in the table RR, Relative Risk; 95% CI, 95% Confidence Interval Table 4 Relative risk of death for colorectal cancer patients from the Philippine resident population and for Non- Hispanic White patients compared to Filipino-American patients from US SEER, 1993-2002 Variable Philippine resident population Filipino-Americans (reference group) Non-Hispanic Whites to Filipino-Americans, the latter showing a slightly more favourable prognosis in comparison to Caucasians in the US. Further analysis showed that Filipinos were less likely to be diagnosed at a localized stage, indicating delay in disease detection. In spite of the availability of early detection methods for CRC, most patients in the Philippines are still diagnosed with an advanced stage disease. From the onset of symptoms, average delay of physician consulta- tion was estimated to be 5 months, while average delay in diagnosis was estimated to be 7 months [36]. On the part of the patients, financial constraints were the main reasons cited for this delay [36], with patients consulting health practitioners only when symptoms become Page 6 of 9 95% CI 0.98 - 1.01 0.99 - 1.09 1.23 - 1.34 1.68 - 1.83 2.96 - 3.21 1.53 - 1.59 6.78 - 7.12 0.71 - 0.74 5.09 - 5.30 1.12 - 1.18