Sočan et al. BMC Public Health 2010, 10:360 http://www.biomedcentral.com/1471-2458/10/360 and drafted the respective section of the manuscript. JL performed mathematical modelling, programming and statistical analysis and drafted the respective sections of the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: 30 November 2009 Accepted: 23 June 2010 Published: 23 June 2010 References 1. Heininger U, Seward JF: Varicella. Lancet 2006, 368:1365-1376. 2. Cameron JC, Allan G, Johnston F, Finn A, Heath PT, Booy R: Severe complications of chickenpox in hospitalised children in the UK and Ireland. Arch Dis Child 2007, 92:1062-1066. 3. Persson A, Bergström T, Lindh M, Namvar L, Studahl M: Varicella-zoster virus CNS disease-Viral load, clinical manifestations and sequels. J Clin Virol 2009, 46:249-253. 4. Liese JG, Grote V, Rosenfeld E, Fischer R, Belohradsky BH, v Kries R, ESPED Varicella Study Group: The burden of varicella complications before the introduction of routine varicella vaccination in Germany. Pediatr Infect Dis J 2008, 27:119-124. 5. Enders G, Miller E, Cradock-Watson J, Bolley I, Ridehalgh M: Consequences of varicella and herpes zoster in pregnancy: prospective study of 1739 cases. Lancet 1994, 343:1548-1551. 6. McKendrick MW, Lau J, Alston S, Bremner J: VZV infection in pregnancy: a retrospective review over 5 years in Sheffield and discussion on the potential utilisation of varicella vaccine in prevention. J Infect 2007, 55:64-67. 7. Brisson M, Edmunds WJ, Law B, Gay NJ, Walld R, Brownell M, et al: Epidemiology of varicella zoster virus infection in Canada and the United Kingdom. Epidemiol Infect 2001, 127:305-314. 8. Lin YH, Huang LM, Chang IS, Tsai FY, Chang LY: Disease burden and epidemiological characteristics of varicella in Taiwan from 2000 to 2005. J Microbiol Immunol Infect 2009, 42:5-12. 9. Baldo V, Baldovin T, Russo F, Busana MC, Piovesan C, Bordignon G, et al: Varicella: epidemiological aspects and vaccination coverage in the Veneto Region. BMC Infect Dis 2009, 9:150. 10. Salleras L, Domínguez A, Vidal J, Plans P, Salleras M, Taberner JL: Seroepidemiology of varicella-zoster virus infection in Catalonia (Spain). Rationale for universal vaccination programmes. Vaccine 2000, 19:183-188. 11. Ratnam S: Varicella susceptibility in a Canadian population. Can J Infect Dis 2000, 11:249-253. 12. Thiry N, Beutels P, Shkedy Z, Vranckx R, Vandermeulen C, Wielen MV, et al: The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium). Eur J Pediatr 2002, 161:588-593. 13. Wutzler P, Färber I, Wagenpfeil S, Bisanz H, Tischer A: Seroprevalence of varicella-zoster virus in the German population. Vaccine 2002, 20:121-124. 14. Gidding HF, MacIntyre CR, Burgess MA, Gilbert GL: The seroepidemiology and transmission dynamics of varicella in Australia. Epidemiol Infect 2003, 131:1085-1089. 15. Alp H, Altinkaynak S, Ertekin V, Kiliçaslan B, Giiraksin A: Seroepidemiology of varicella-zoster virus infection in a cosmopolitan city (Erzurum) in the eastern Turkey. Health Policy 2005, 72:119-124. 16. Nardone A, de Ory F, Carton M, Cohen D, van Damme P, Davidkin I, et al: The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region. Vaccine 2007, 25:7866-7872. 17. Lee BW: Review of varicella zoster seroepidemiology in India and Southeast Asia. Trop Med Int Health 1998, 3:886-890. 18. Liyanage NP, Fernando S, Malavige GN, Mallikahewa R, Sivayogan S, Jiffry MT, et al: Seroprevalence of varicella zoster virus infections in Colombo district, Sri Lanka. Indian J Med Sci 2007, 61:128-134. 19. WHO: The WHOposition paper on varicella vaccines. Wkly Epidemiol Rec 1998, 73:241-248. 20. Bonanni P, Breuer J, Gershon A, Gershon M, Hryniewicz W, Papaevangelou V, et al: Varicella vaccination in Europe - taking the practical approach. BMC Med 2009, 7:26. 21. Gabutti G, Rota MC, Guido M, De Donno A, Bella A, degli Atti ML, Seroepidemiology Group, et al: The epidemiology of Varicella Zoster Virus infection in Italy. BMC Public Health 2008, 8:372. Page 6 of 6 22. Edmunds WJ, Brisson M: The effect of vaccination on the epidemiology of varicella zoster virus. J Infect 2002, 44:211-219. 23. Brisson M, Melkonyan G, Drolet M, De Serres G, Thibeault R, De Wals P: Modeling the impact of one- and two-dose varicella vaccination on the epidemiology of varicella and zoster. Vaccine 2010, 28:3385-3397. 24. CDC: Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2007, 56:(No. RR4). 25. Edmunds WJ, Pebody RG, Aggerback H, Baron S, Berbers G, Conyn-van Spaendonck MA, et al: The sero-epidemiology of diphtheria in Western Europe. ESEN Project. European Sero-Epidemiology Network. Epidemiol Infect 2000, 125:113-125. 26. Heininger U, Deshgrandchamps D, Schaad UB: Seroprevalence of Varicella- Zoster virus IgG antibodies in Swiss children during the first 16 months of age. Vaccine 2006, 24:3258-3260. 27. Mossong J, Putz L, Schneider F: Seroprevalence and force of infection of varicella-zoster virus in Luxembourg. Epidemiol Infect 2004, 132:1121-1127. 28. Griffiths DA: A catalytic model of infection for measles. Appl Statist 1974, 23:330-339. 29. Farrington CP: Modelling forces of infection for measles, mumps and rubella. Stat Med 1990, 9:953-967. 30. Armitage P, Berry G, Matthews JNS: Statistical methods in medical research Oxford: Blackwell, Williston 2002, 414. 31. R Development Core Team: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria [http:// www.R-project.org], ISBN 3-900051-07-0. 32. Gail MH, Benichou J: Encyclopedia of Epidemiologic Methods Chichester: John Wiley & Sons 2000, 220-221. 33. Whitaker HJ, Farrington CP: Estimation of infectious disease parameters from serological survey data: the impact of regular epidemics. Stat Med 2004, 23:2429-2433. 34. Ogunjimi B, Hens N, Goeyvaerts N, Aerts M, Van Damme P, Beutels P: Using empirical social contact data to model person to person infectious disease transmission: An illustration for varicella. Math Biosci 2009, 218:80-87. 35. Kelly H, Riddell MA, Gidding HF, Nolan T, Gilbert GL: Random cluster survey and a convenience sample give comparable estimates of immunity to vaccine preventable diseases in children of school age in Victoria, Australia. Vaccine 2002, 20:3130-3126. 36. Pinquier D, Gagneur A, Balu L, Brissaud Q, Gras Le Guen C, Hau-Rainsard I, et al: Prevalence of anti-varicella-zoster virus antibodies in French infants under 15 months of age. Clin Vaccine Immunol 2009, 16:484-487. 37. Pre-school education in kindergartens, Slovenia, school year 2008/2009. Statistical office of Republic of Slovenia [http://www.stat.si/novica_prikazi. aspx?id=2327]. 38. Sočan M, Blasko M: Surveillance of varicella and herpes zoster in Slovenia 1996 - 2005. Euro Surveill 2007, 12:2. 39. Jerant AF, DeGaetano JS, Epperly TD, Hannapel AC, Miller DR, Lloyd AJ: Varicella susceptibility and vaccination strategies in young adults. J Am Board Fam Pract 1998, 11:296-306. 40. Sočan M: Evaluation of mandatory case-based reporting system for varicella in the prevaccine era. Cent Eur J Public Health 2010, 18:99-103. 41. Yu AL, Amaku M, Burattini MN, Massad E, Azavedo RS: Varicella transmission in two samples of children with different social behaviour in State of São Paolo, Brazil. Epidemiol Infect 2001, 127:493-500. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2458/10/360/prepub doi:10.1186/1471-2458-10-360 Cite this article as: Sočan et al.: Varicella susceptibility and transmission dynamics in Slovenia. BMC Public Health 2010 10:360.