Turner et al. BMC Public Health 2010, 10:170 http://www.biomedcentral.com/1471-2458/10/170 Page 4 of 12 Table 3 References for Cochrane systematic reviews and protocols potentially relevant to each of the guidelines Guideline Cochrane systematic reviews Protocols for reviews Reviews with no included studies from developing settings Infant and Young Child Feeding in Emergencies [4] [18-31] Community-based [20,23,26,38-69] Therapeutic Care (CTC) A Field Manual [7] Guiding principles for feeding infants and young children during emergencies [8] Antenatal Guidelines For Primary Health Care In Crisis Conditions [5] Emergency Field Handbook: A Guide For UNICEF Staff [6] Manual for the health care of children in humanitarian emergencies[9] [32-37] [32,34,35,37,70-77] [32,34,35,37,71,73,75,87-89] [21,24] [66] Unclear: [60-62] [66,79], Unclear: [60-62,81]. [91,92,95,99,101,107,108,116, 117,121,125,127, 128,130,134,135,138,141,147,151,162,163,167, 171,172,176,177,179,180,182,184,186,192,194] Unclear: [60,61,90,96,98,100,106,109-111,114,119,129,131, 132,140,146,149,150,157,158,166,173,175,188,193] [18,19,22,23,25-28,30,31,44,48,49, 53,58,60-62,64-69,78-86] [25,27,28,30,31,48,60,61,64,90-194] [195-206] [18,19,22,26,27,39-43,45-48,50-54,56-59, 61-63,65-69,78,83-85,105,191,207-231] [35,36,73-75,77,87,88,232-244] [66,207,213,222-224,230], Unclear: [61,62]. [18,22,23,26,28,30,31,39-43,45-47,53,54,56,57, 59,62,78,83-86,105,207,208,210,215,216,218, 222,223,225,226,228-230,245-257] [36,37,233,235,237,238,241,258] [207,223,230,250] Unclear: [62,248,255] developing settings. However for large portions of the guideline, particularly those focusing on procurement and distribution of infant formula, and coordinating, monitoring and assessing the success of feeding pro- grams, there were no relevant reviews in The Cochrane Library. For the Valid International Guideline “Community- based Therapeutic Care (CTC) A Field Manual” [7], which focuses on nutritional support for children, pregnant and lactating women, there were 35 poten- tially relevant Cochrane systematic reviews and 12 pro- tocols. All of the reviews except one appeared to include studies from developing settings, however in three reviews the study settings were unclear. The potentially relevant reviews focused primarily on the effectiveness of supplementation with particular nutri- ents and choice of treatment for malaria. There were no relevant reviews addressing assessing malnutrition, planning, establishing, monitoring or evaluating a nutrition supplement program, which makes up the majority of the field manual. There were 34 Cochrane reviews and 10 protocols potentially relevant to the World Health Organization’s “Guiding principles for feeding infants and young chil- dren during emergencies” [8] guideline. As with the pre- vious two guidelines, these reviews were primarily related to nutritional supplementation for infants and their mothers, as well as support for establishment and maintenance of breastfeeding. All but two trials appeared to include studies from developing settings, however in four reviews the study settings were unclear. For the guideline addressing antenatal care “Antenatal Guidelines For Primary Health Care In Crisis Condi- tions” [5] produced by the International Committee of the Red Cross, there were 114 Cochrane systematic reviews and 12 protocols that were potentially relevant. The majority of these reviews addressed clinical man- agement of hypertension, pre-eclampsia and eclampsia; or management of premature labour. For 34 of these reviews there were no included studies from developing settings, and in an additional 25 it was unclear how many studies were conducted in developing settings. The proportion of potentially relevant reviews where the included studies were all conducted in developed set- tings, or the setting was unclear was much larger for this guidelines than the others. The “Emergency Field Handbook: A Guide For UNI- CEF Staff” [6] produced by UNICEF covers provision of protection and assistance to children and women in emergencies including: assessment, co-ordination, pro- gram delivery, security, communication, logistics and human resources. Sixty-two Cochrane systematic reviews and 21 protocols were potentially relevant to the content of this handbook; however, almost all of