Grutsch et al. BMC Cancer 2011, 11:193 http://www.biomedcentral.com/1471-2407/11/193 Page 6 of 13 Figure 1 Comparison of the circadian activity rhythm of healthy controls and lung cancer patients. Healthy controls (A) show a more robust circadian activity rhythm compared to lung cancer inpatients and outpatients combined (B). Outpatients (C) have better circadian organization of sleep/activity compared to the hospitalized group (D). Concurrent plot of all groups (E) shows that peak daytime activity is compromised in all lung cancer patients and especially among hospitalized ones. Nightly sleep is, however, markedly and identically disturbed among lung cancer patients regardless of where it is measured.