BMC Cancer 2008, 8:59 http://www.biomedcentral.com/1471-2407/8/59 21. Montgomery J, Wittwer CT, Kent JO, Zhou L: Scanning the cystic fibrosis transmembrane conductance regulator gene using high-resolution DNA melting analysis. Clin Chem 2007, 53(11):1891-1898. 22. Gowen LC, Johnson BL, Latour AM, Sulik KK, Koller BH: Brca1 defi- ciency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat Genet 1996, 12(2):191-194. 23. Dufresne SD, Belloni DR, Wells WA, Tsongalis GJ: BRCA1 and BRCA2 mutation screening using SmartCycler II high-reso- lution melt curve analysis. Arch Pathol Lab Med 2006, 130(2):185-187. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/8/59/prepub Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Page 7 of 7 (page number not for citation purposes)