BMC Cancer 2009, 9:397 http://www.biomedcentral.com/1471-2407/9/397 a southern European population: the role of glutathione S- transferases GSTM1, GSTM3, and GSTT1 genetic polymor- phisms. Prostate 2004, 58:414-420. 50. Kidd LR, Woodson K, Taylor PR, Albanes D, Virtamo J, Tangrea JA: Polymorphisms in glutathione-S-transferase genes (GST- M1, GST-T1 and GST-P1) and susceptibility to prostate can- cer among male smokers of the ATBC cancer prevention study. Eur J Cancer Prev 2003, 12:317-320. 51. McCarty KM, Santella RM, Steck SE, Cleveland RJ, Ahn J, Ambrosone CB, et al.: PAH-DNA adducts, cigarette smoking, GST poly- morphisms, and breast cancer risk. Environ Health Perspect 2009, 117:552-558. 52. Mir O, Alexandre J, Tran A, Durand JP, Pons G, Treluyer JM, et al.: Relationship between GSTP1 Ile(105)Val polymorphism and docetaxel-induced peripheral neuropathy: clinical evidence of a role of oxidative stress in taxane toxicity. Ann Oncol 2009, 20:736-740. 53. Sreeja L, Syamala V, Hariharan S, Syamala VS, Raveendran PB, Sivanan- dan CD, et al.: Glutathione S-transferase M1, T1 and P1 poly- morphisms: susceptibility and outcome in lung cancer patients. J Exp Ther Oncol 2008, 7:73-85. 54. Rybicki BA, Neslund-Dudas C, Nock NL, Schultz LR, Eklund L, Ros- bolt J, et al.: Prostate cancer risk from occupational exposure to polycyclic aromatic hydrocarbons interacting with the GSTP1 Ile105Val polymorphism. Cancer Detect Prev 2006, 30:412-422. 55. Loeb S, Catalona WJ: What is the prognostic impact of positive surgical margins in surgically treated prostate cancer? Nat Clin Pract Urol 2006, 3:418-419. 56. Shriver MD, Kittles RA: Genetic ancestry and the search for personalized genetic histories. Nat Rev Genet 2004, 5:611-618. 57. Kittles RA, Chen W, Panguluri RK, Ahaghotu C, Jackson A, Ade- bamowo CA, et al.: CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification? Hum Genet 2002, 110:553-560. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/9/397/pre pub Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Page 10 of 10 (page number not for citation purposes)