BMC Cancer 2007, 7:218 http://www.biomedcentral.com/1471-2407/7/218 35. Nollet F, Berx G, Van Roy F: The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer. Mol Cell Biol Res Commun 1999, 2(2):77-85. 36. Anderson E: The role of oestrogen and progesterone recep- tors in human mammary development and tumorigenesis. Breast Cancer Res 2002, 4(5):197-201. 37. Reis-Filho JS, Torio B, Albergaria A, Schmitt F: p63 expression in normal skin and usual cutaneous carcinomas. J Cutan Pathol 2002, 29(9):517-23. 38. Shick PC, Riordan GP, Foss RD: Estrogen and progesterone receptors in salivary gland adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995, 80(4):440-4. 39. Porrelo A, Cardelli P, Spugnini EP: Pet models in cancer research: general principles. J Exp Clin Cancer Res 2004, 23(2):181-93. 40. McLeod KF, Jacks T: Insights into cancer from transgenic mouse models. J Pathol 1999, 187(1):43-60. 41. Rivera EM: Mammary gland culture. In Methods in Mammalian Embryology Edited by: Daniel JC Jr. San Francisco: WH Freeman Com- pany; 1971. 42. Vail DM, MacEwen EG: Spontaneously occurring tumors of companion animals as models for human cancer. Cancer Invest 2000, 18(8):781-92. 43. Schneider R, Dorn CR, Taylor DO: Factors influencing canine mammary cancer development and postsurgical survival. J Natl Cancer Inst 1969, 43(6):1249-61. 44. Genelhu MC, Gobbi H, Soares FA, Campos AH, Ribeiro CA, Cassali GD: Immunohistochemical expression of p63 in pleomorphic adenomas and carcinomas ex-pleomorphic adenomas of sal- ivary glands. Oral Oncol 2006, 42(2):154-60. 45. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, Andrews NC, Caput D, McKeon F: p63, a p53 homolog at 3q27–29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Molecular Cell 1998, 2(3):305-16. 46. Shih HC, Shiozawa T, Miyamoto T, Kashima H, Feng YZ, Kurai M, Konishi I: Immunohistochemical expression of E-cadherin and beta-catenin in the normal and malignant human endometrium: an inverse correlation between E-cadherin and nuclear beta-catenin expression. Anticancer Res 2004, 24(6):3843-50. 47. Harrington KJ, Syrigos KN: The role of E-cadherin-catenin com- plex: more than intercellular glue? Ann Surg Oncol 2000, 7(10):783-8. Erratum in: Ann Surg Oncol 2001 Mar, 8(2):186. 48. Shiozaki H, Oka H, Inoue M, Tamura S, Monden M: E-cadherin mediated adhesion system in cancer cells. Cancer 77(8 Suppl):1605-13. 1996 Apr 15 49. Genelhu MC, Gobbi H, Arantes DC, Cardoso SV, Cassali GD: Immunolocalization of beta-Catenin in Pleomorphic Adeno- mas and Carcinomas Ex-pleomorphic Adenomas of Salivary Glands. Appl Immunohistochem Mol Morphol 2007, 15(3):273-278. 50. Hamilton JM, Else RW, Forshaw P: Oestrogen receptors in canine mammary tumours. Vet Rec 101(13):258-60. 1977 Sep 24 51. Graham JC, O'Keefe DA, Gelberg HB: Immunohistochemical assay for detecting estrogen receptors in canine mammary tumors. Am J Vet Res 1999, 60(5):627-30. 52. Nieto A, Peña L, Perez-Alenza MD, Sanchez MA, Flores JM, Castano M: Immunohistologic detection of estrogen receptor alpha in canine mammary tumors: clinical and pathologic associa- tions and prognostic significance. Vet Pathol 2000, 37(3):239-47. 53. Miller AS, Hartman GG, Sow-Yeh C, Edmonds PR, Brightman SA, Harwick RD: Estrogen receptor assay in polymorphous low- grade adenocarcinoma and adenoid cystic carcinoma of sali- vary gland origin. An immunohistochemical study. Oral Surg Oral Med Oral Pathol 1994, 77(1):36-40. 54. Dori S, Trougouboff P, David R, Buchner A: Immunohistochemi- cal evaluation of estrogen and progesterone receptors in adenoid cystic carcinoma of salivary gland origin. Oral Oncol 2000, 36(5):450-3. 55. Jeannon JP, Soames JV, Bell H, Wilson JA: Immunohistochemical detection of oestrogen and progesterone receptors in sali- vary tumours. Clin Otolaryngol Allied Sci 1999, 24(1):52-4. 56. Gaffney EV, Pinkstone JA, Eidson JJ: Estrogen receptors in parotid tumors. Endocr Res 1995, 21(3):635-43. 57. Leimola-Virtanen R, Salo T, Toikkanen S, Pulkkinen J, Syrjänen S: Expression of estrogen receptor (ER) in oral mucosa and sal- ivary glands. Maturitas 2000, 36(2):131-7. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/7/218/pre pub Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Page 9 of 9 (page number not for citation purposes)