Zhou et al. BMC Cancer 2011, 11:494 http://www.biomedcentral.com/1471-2407/11/494 9. Laparoscopy and/or Fast Track Multimodal Management Versus Standard Care (LAFA) Study Group and the Enhanced Recovery after Surgery (ERAS) Group: Systematic review of enhanced recovery programmes in colonic surgery. Br J Surg 2006, 93(7):800-809. 10. Kehlet H, Wilmore DW: Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg 2008, 248(2):189-198. 11. Counihan TC, Favuzza J: Fast track colorectal surgery. Clin Colon Rectal Surg 2009, 22(1):60-72. 12. Enhanced Recovery After Surgery (ERAS) Group: Consensus review of optimal perioperative care in colorectal surgery: enhanced recovery after surgery (ERAS) group recommendations. Arch Surg 2009, 144(10):961-969. 13. Gouvas N, Tan E, Windsor A, Xynos E, Tekkis PP: Fast-track vs standard care in colorectal surgery: a meta-analysis update. Int J Colorectal Dis 2009, 24(10):1119-1131. 14. Eskicioglu C, Forbes SS, Aarts MA, Okrainec A, McLeod RS: Enhanced recovery after surgery (ERAS) programs for patients having colorectal surgery: a meta-analysis of randomized trials. J Gastrointest Surg 2009, 13(12):2321-2329. 15. Schmoll HJ, Cartwright T, Tabernero J, Nowacki MP, Figer A, Maroun J, Price T, Lim R, Van Cutsem E, Park YS, McKendrick J, Topham C, Soler- Gonzalez G, de Braud F, Hill M, Sirzén F, Haller DG: Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: a planned safety analysis in 1,864 patients. J Clin Oncol 2007, 25(1):102-109. 16. Cassidy J, Tabernero J, Twelves C, Brunet R, Butts C, Conroy T, Debraud F, Figer A, Grossmann J, Sawada N, Schöffski P, Sobrero A, Van Cutsem E, Díaz-Rubio E: XELOX (capecitabine plus oxaliplatin): active first-line therapy for patients with metastatic colorectal cancer. J Clin Oncol 2004, 22(11):2084-2091. 17. Haller D, Tabernero J, Maroun J, de Braud F, Price T, Van Cutsem E, Hill M, Gilberg F, Rittweger K, Schmoll H: First efficacy findings from a randomized phase III trial of capecitabine + oxaliplatin versus bolus 5- FU/LV for stage III colon cancer (NO16968/XELOXA study)[abstract 5LBA]. Eur J Cancer 2009, 7(3 suppl):4. 18. Enhanced Recovery After Surgery (ERAS) Group: Length of stay: an inappropriate readout of the success of enhanced recovery programs. World J Surg 2008, 32(6):971-975. 19. Zutshi M, Delaney CP, Senagore AJ, Mekhail N, Lewis B, Connor JT, Fazio VW: Randomized controlled trial comparing the controlled rehabilitation with early ambulation and diet pathway versus the controlled rehabilitation with early ambulation and diet with preemptive epidural anesthesia/analgesia after laparotomy and intestinal resection. Am J Surg 2005, 189(3):268-272. 20. Otchy D, Hyman NH, Simmang C, Anthony T, Buie WD, Cataldo P, Church J, Cohen J, Dentsman F, Ellis CN, Kilkenny JW, Ko C, Moore R, Orsay C, Place R, Rafferty J, Rakinic J, Savoca P, Tjandra J, Whiteford M: Standards practice task force; American society of colon and rectal surgeons: practice parameters for colon cancer. Dis Colon Rectum 2004, 47(8):1269-1284. 21. Tjandra JJ, Kilkenny JW, Buie WD, Hyman N, Simmang C, Anthony T, Orsay C, Church J, Otchy D, Cohen J, Place R, Denstman F, Rakinic J, Moore R, Whiteford M: Standards practice task force; American society of colon and rectal surgeons: practice parameters for the management of rectal cancer (revised). Dis Colon Rectum 2005, 48(3):411-423. 22. Raue W, Haase O, Junghans T, Scharfenberg M, Müller JM, Schwenk W: ’Fast-track’ multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy: a controlled prospective evaluation. Surg Endosc 2004, 18(10):1463-1468. 23. King PM, Blazeby JM, Ewings P, Franks PJ, Longman RJ, Kendrick AH, Kipling RM, Kennedy RH: Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme. Br J Surg 2006, 93(3):300-308. 24. Carli F, Charlebois P, Baldini G, Cachero O, Stein B: An integrated multidisciplinary approach to implementation of a fast-track program for laparoscopic colorectal surgery. Can J Anaesth 2009, 56(11):837-842. 25. Patel GN, Rammos CK, Patel JV, Estes NC: Further reduction of hospital stay for laparoscopic colon resection by modifications of the fast-track care plan. Am J Surg 2010, 199(3):391-394, discussion 394-395. Page 10 of 10 26. Tsikitis VL, Holubar SD, Dozois EJ, Cima RR, Pemberton JH, Larson DW: Advantages of fast-track recovery after laparoscopic right hemicolectomy for colon cancer. Surg Endosc 2010, 24(8):1911-1916. 27. Ding KF, Chen R, Zhang JL, Li J, Xu YQ, Lv L, Wang XC, Sun LF, Wang JW, Zheng S, Zhang SZ: Laparoscopic surgery for the curative treatment of rectal cancer: results of a Chinese three-center case-control study. Surg Endosc 2009, 23(4):854-861. 28. Li M, Gu J: Changing patterns of colorectal cancer in China over a period of 20 years. World J Gastroenterol 2005, 11(30):4685-4688. 29. NCCN clinical practice guidelines in oncology-colon cancer guideline 2009 (Version2.2009). [http://www.nccn.org/professionals/physician_gls/ f_guidelines.asp]. 30. Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM, Heath RM, Brown JM, UKMRC CLASICC Trial Group: Randomized trial of laparoscopic- assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC trial group. J Clin Oncol 2007, 25(21):3061-3068. 31. Li J, Chen R, Xu YQ, Wang XC, Zheng S, Zhang SZ, Ding KF: Impact of a laparoscopic resection on the quality of life in rectal cancer patients: results of 135 patients. Surg Today 2010, 40(10):917-922. 32. Ding KF, Ying XJ, Li J, Li G, Chen ZL, Wang ZH, Lv K, Zhou JJ, Ma YY, Zhang SZ: The interim analysis of an open nonrandomized prospective study comparing laparoscopic surgery with XELOX chemotherapy and open surgery with mFOLFOX6 chemotherapy for resectable colorectal cancer [abstract 693]. Ann Oncol 2010, 21(suppl 8):viii220. 33. MacKay G, Ihedioha U, McConnachie A, Serpell M, Molloy RG, O’Dwyer PJ: Laparoscopic colonic resection in fast-track patients does not enhance short-term recovery after elective surgery. Colorectal Dis 2007, 9(4):368-372. 34. Bartels SA, Vlug MS, Ubbink DT, Bemelman WA: Quality of life after laparoscopic and open colorectal surgery: a systematic review. World J Gastroenterol 2010, 16(40):5035-5041. 35. Khan S, Gatt M, MacFie J: Enhanced recovery programmes and colorectal surgery: does the laparoscope confer additional advantages? Colorectal Dis 2009, 11(9):902-908. 36. Wind J, Hofland J, Preckel B, Hollmann MW, Bossuyt PM, Gouma DJ, van Berge Henegouwen MI, Fuhring JW, Dejong CH, van Dam RM, Cuesta MA, Noordhuis A, de Jong D, van Zalingen E, Engel AF, Goei TH, de Stoppelaar IE, van Tets WF, van Wagensveld BA, Swart A, van den Elsen MJ, Gerhards MF, de Wit LT, Siepel MA, van Geloven AA, Juttmann JW, Clevers W, Bemelman WA: Perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care (LAFA trial). BMC Surg 2010, 29:6-16. 37. Winterhalder R, Delmore G, Hardegger T, Urspruch A, Hieke K: Cost comparison: capecitabine + oxaliplatin(XELOX) vs 5-FU/LV + oxaliplatin (FOLFOX4) in the adjuvant treatment of patients with colon cancer(ACC) [abstract 622P]. Ann Oncol 2010, 21(suppl 8):viii201. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/11/494/prepub doi:10.1186/1471-2407-11-494 Cite this article as: Zhou et al.: Fast track multi-discipline treatment (FTMDT trial) versus conventional treatment in colorectal cancer–the design of a prospective randomized controlled study. BMC Cancer 2011 11:494.