Herzig et al. BMC Genomics 2010, 11:100 http://www.biomedcentral.com/1471-2164/11/100 Page 7 of 19 Figure 3 TRDV gene sequences. (A) TRDV deduced amino acid sequences were aligned with ClustalW2 using the default parameters and visualized with JalView. Analysis included all non-redundant genomic sequences (see Table 1 for GLEAN identification numbers). IMGT unique numbering for V-DOMAIN [29,32] is indicated above the alignment and conserved cysteines are indicated below the alignment. (B) IMGT Collier de Perles [33] are shown for TRDV1 (based on TRDV1a, GLEAN_22158), TRDV2-1 (no glean identification), TRDV3-1 (no glean identification) and TRDV4 (GLEAN_19724) and were determined using IMGT/V-QUEST [32]. The CDR-IMGT lengths are indicated.