BMC Genomics 2006, 7:133 http://www.biomedcentral.com/1471-2164/7/133 FNiugmurbeer3of BSs of 19 TFs (see text) on the 500 bp region upstream of 13686 genes Number of BSs of 19 TFs (see text) on the 500 bp region upstream of 13686 genes. A DNA sequence was considered to be a BS if its score was higher than Tmax. The BS were counted separately for on (blue) and off Alu (red) 7 appearance. For 7 out of 19 TFs the majority of the putative BSs reside on Alu. (A) developmental TFs (B) other TFs. The distributions of B1 in mouse promoters and Alu in human promoters are positively correlated When the mouse genome was first sequenced, regions orthologous to human DNA were identified. The densities of B1 and B2 in mouse and Alu in human were measured in windows of 500,000 bp and the Alu density in humans was found to be correlated with B2 and B1 density in mouse [49]. A high correlation was quite unexpected, WoFuigesubpriroeelso4egnictafloprr6ocTeFssetshe number of putative BSs in the 5 Kbp region upstream, averaged over the genes that belong to vari- We present for 6 TFs the number of putative BSs in the 5 Kbp region upstream, averaged over the genes that belong to vari- ous biological processes. The 6 TFs shown were chosen because their BSs are non-overlapping and their Tmax is greater than T5 (see text) a. for on-Alu BSs b. all BSs(on and off Alu). Page 10 of 15 (page number not for citation purposes)