BMC Cancer 2009, 9:11 http://www.biomedcentral.com/1471-2407/9/11 Table 2: Genes differentially expressed between oral tongue tumor and case-matched histologically normal mucosae (TN paired, n = 20) Average log fold change Accession AJ001381 D28364 M92383 U22431 M86400 L19779 U10860 U12472, U21689 J04173 AL009179 D13748 S79639 AL049650 D26599 X82554 U40490 D83407 NM001953, M63193 M77349 U73377 M35252 AF054183 U78525 Sequence identity (GenBank/EMBL) Nuclear proteins (transcription factors, DNA processing enzymes) Mutated allele of a myosin class I, myh-1c Annexin II Thymosin beta-10 Hypoxia-inducible factor 1 alpha (HIF-1 alpha) Phospholipase A2 Histone H2A.2 Guanosine 5-monophosphate synthase Glutathione S-transferase (GST phi) Phosphoglycerate mutase (PGAM-B) Histone H2B Eukaryotic initiation factor 4AI Exostosin 1 (EXT1) snRNP (small nuclear ribonucleoprotein particle) protein B) Ras-Like Protein Tc4 Proteasome subunit HsC7-I SPHAR gene for cyclin-related protein Human nicotinamide nucleotide transhydrogenase ZAKI-4 in human skin fibroblast Cytokines, growth factors and receptors Platelet-derived endothelial cell growth factor (ECGF1) Transforming growth factor-beta induced gene product (BIGH3) p66shc (SHC) Tumor associated antigen CO-029 Signaling molecules GTP binding protein Eukaryotic translation initiation factor (eIF3) 5.24 4.61 3.75 3.47 3.27 2.99 2.71 2.70 2.69 2.58 2.57 2.39 2.35 2.27 2.04 -1.89 -3.53 -5.31 15.89 6.17 2.37 -9.42 2.00 1.89 Page 5 of 13 (page number not for citation purposes)