Holden et al. BMC Public Health 2010, 10:96 http://www.biomedcentral.com/1471-2458/10/96 multiple comparisons p < 0.01 was used as the criterion for statistical significance. Logistic regression analyses were performed using Stata 8.0 (Stata Corporation, Col- lege Station, Texas). Results Association of lifestyle factors with male reproductive health disorders Waist Circumference When controlling for age only, men with a waist cir- cumference of < 94 cm were significantly less likely to report erectile problems (ED) and perceived androgen deficiency (pAD) while those with a large waist circum- ference (>102 cm) had a higher likelihood of ED com- pared to men in the medium waist circumference category but this did not reach statistical significance (Table 1). When each outcome variable was adjusted for all lifestyle factors, co-morbid diseases and medication use (Figure 1), the strength of the association between large waist circumference and ED was reduced. Waist Page 4 of 9 circumference was not associated with either LUTS or prostate disease. Body Mass Index (BMI) Underweight men were more likely to report erectile problems (ED) and pAD in age-adjusted and fully adjusted models. Obesity was positively associated with ED and pAD in age-adjusted analyses (Table 1) but in fully adjusted models obesity was not signifi- cantly associated with any reproductive health disor- ders (Figure 1). Alcohol consumption Moderate alcohol consumption was associated with lower risk of ED and LUTS when controlling for age (Table 1) but these associations were attenuated in the fully adjusted models and the confidence intervals included the value (Figure 1). Excessive alcohol consumption as defined by high risk drinking behaviour was not significantly associated with any reproductive health disorder compared to the abstaining group (Table 1 & Figure 1). Figure 1 Associations of male reproductive health disorders with a range of lifestyle factors and biomedical determinants. Associations of male reproductive health disorders with a range of lifestyle factors and biomedical determinants in middle-aged and older Australian men. Each model controls for age, waist circumference, BMI, smoking, alcohol consumption, physical activity, co-morbid disease and medication use for high blood pressure, high cholesterol and depression. Adjusted ORs and 95% CIs are presented.