Liang et al. BMC Genomics 2011, 12:231 http://www.biomedcentral.com/1471-2164/12/231 Table 2 The number of DS-DMRs in different tissues Total Adjusted# %1 CpGi-Prom %2 Brain: Common E15_uniq E15+NB NB_uniq AD_uniq NB+AD E15+AD Total* UnMe-AD** Me-AD*** Heart: Common E15_uniq E15+NB NB_uniq AD_uniq NB+AD E15+AD Total* UnMe-AD** Me-AD*** Liver: Common E15_uniq E15+NB NB_uniq AD_uniq NB+AD E15+AD Total* UnMe-AD** Me AD*** Testis: Common E15_uniq E15+NB NB_uniq AD_uniq NB+AD E15+AD Total UnMe-AD** Me-AD*** Grand Total: Common DS-DMRs UnMe-AD** Me-AD*** 1903 533 490 370 408 70 65 1936 1393 543 1844 46 87 93 172 246 27 671 226 445 1497 117 1419 147 468 36 194 2381 1683 698 570 272 939 798 2214 63 62 4348 2009 2339 5814 9336 5311 4025 533 509 400 532 82 77 2132 1442 691 81 125 112 172 253 34 777 318 459 119 1431 147 813 46 249 2804 1696 1107 380 1094 789 2336 65 91 4755 2263 2493 10469 5719 4750 ND 27.5 25.3 19.1 21.1 3.6 3.4 100.0 72.0 28.0 ND 6.9 13.0 13.9 25.6 36.7 4.0 100.0 33.7 66.3 ND 4.9 60.0 6.2 19.7 1.5 8.1 100.0 70.7 29.3 ND 6.3 22.0 18.4 50.9 1.4 1.4 100.0 40.8 47.6 ND 100.0 56.9 43.1 182 105 66 55 94 5 11 336 226 110 218 27 17 12 45 44 6 151 56 95 141 25 198 24 70 2 13 332 247 85 20 105 193 231 71 3 5 608 529 79 561 1427 1058 369 9.6 19.7 13.5 14.9 23.0 7.1 16.9 15.2 16.2 20.3 11.8 58.7 19.5 12.9 26.2 17.9 22.2 22.4 24.8 21.3 9.4 21.4 14.0 16.3 15.0 5.6 6.7 13.9 14.7 12. 3.5 38.6 20.6 28.9 3.2 4.8 8.1 14.0 26.3 3.4 9.6 15.3 19.9 9.2 %1: percentage is based on the row total vs. total DMRs; %2: percentage is based on the total of DMRs in the row; Total*: Stage specific; UnMe-AD**: unmethylated in AD but methylated in E15 and/or NB; Me-AD***: methylated in Adult but unmethylated in E15 and/or NB; Adjusted#: number of DMRs adjusted based on the adjusted coefficiency between the duplicated samples. non-CpGi-Prom Intra-genic CpGi Inter-genic CpGi 210 34 27 25 29 9 1 125 86 39 189 9 5 10 11 16 1 52 24 28 205 8 62 6 31 1 20 128 76 52 39 33 109 90 70 3 5 310 232 78 643 615 418 197 Page 5 of 16 %2 11.0 6.4 5.5 6.8 7.1 12.9 1.5 8.4 6.2 7.2 10.2 19.6 5.7 10.8 6.4 6.5 3.7 7.7 10.6 6.3 13.7 6.8 4.4 4.1 6.6 2.8 10.3 5.4 4.5 7.4 6.8 12.1 11.6 11.3 3.2 4.8 8.1 7.1 11.5 3.3 11.1 6.6 7.9 4.9 1018 359 368 248 233 40 46 1294 975 319 946 8 61 64 83 132 15 363 133 230 726 74 1034 109 322 30 130 1699 1217 482 363 101 480 391 1908 48 38 2966 972 1994 3053 6322 3297 3025 %2 53.5 67.4 75.1 67.0 57.1 57.1 70.8 62.6 70.0 58.8 51.3 17.4 70.1 68.8 48.3 53.7 55.6 54.1 58.8 51.7 48.5 63.2 72.9 74.1 68.8 83.3 67.0 71.4 72.3 69.1 63.7 37.1 51.1 49.0 86.2 76.2 61.3 68.2 48.4 85.3 52.5 67.7 62.1 75.2 493 35 29 42 52 16 7 181 106 75 491 2 4 7 33 54 5 105 13 92 425 10 125 8 45 3 31 222 143 79 148 33 157 86 165 9 14 464 276 188 1557 972 538 434 %2 25.9 6.6 5.9 11.4 12.7 22.9 10.8 13.9 7.6 13.8 26.6 4.3 4.6 7.5 19.2 22.0 18.5 15.6 5.8 20.7 28.4 8.5 8.8 5.4 9.6 8.3 16.0 9.3 8.5 11.3 26.0 12.1 16.7 10.8 7.5 14.3 22.6 10.7 13.7 8.0 26.8 10.4 10.1 10.8