BMC Cancer 2005, 5:106 http://www.biomedcentral.com/1471-2407/5/106 Authors' contributions KP conceived of the case, participated in the sequence alignment, drafted and revised the manuscript before and following the peer review. M K-l conceived of the case, had access to the data, participated in the sequence alignment and drafted the manuscript. References 1. Miller RW, Rabkin CS: Merkel cell carcinoma and melanoma: etiological similarities and differences. Cancer Epidemiol Biomar- kers Prev 1999, 8:153-158. 2. Ratner D, Nelson BR, Brown MD, Johnson TM: Merkel cell carcinoma. J Am Acad Dermatol 1993, 29:143-156. 3. Raaf JH, Urmacher C, Knapper WK, Shiu MH, Cheng EW: Trabecu- lar (Merkel cell) carcinoma of the skin. Cancer 1986, 57:178. 4. Goepfert H, Remmer D, Silva E, Wheeler B: Merkel cell carcinoma (Endocrine carcinoma of the skin) of the head and neck. Arch Otolaryngol 1984, 110:707-712. 5. Sibley R, Dehner L, Rosai J: Primary neuroendocrine (Merkel cell?) carcinoma of the skin. Am J Surg Pathol 1985, 9:95-108. 6. O'Connor WJ, Roenigk RK, Broadland DG: Merkel cell carci- noma: comparison of Mohs micrographic surgery and wide excision in eighty-six patients. Dermatol Surg 1997, 23:929-33. 7. Tong CK, Toker C: Trabecular carcinoma of the skin: An ultrastructural study. Cancer 1978, 42:2311-2321. 8. Gollard R, Weber R, Kosty MP, Greenway HT, Massullo V, Humber- son C: Merkel cell carcinoma: Review of 22 cases with surgi- cal, pathologic and theraupetic considerations. Cancer 2000, 88:1842-51. 9. Moll R, Moll I, Franke WW: Identification of Merkel cell in human skin by specific cytocheratin antibodies: Changes in cell density and distribution in fetal and adult plantar epidermis. Differentiation 1984, 28:136. 10. Michels S, Swanson PE, Robb JA, Wick MR: Leu-7 in small cell neo- plasms: An immunoistochemical study with ultrastructural correlations. Cancer 1987, 60:2958. 11. Merot Y, Margolis RG, Dahl D, Saurat JH, Mihm MC Jr: Coexpres- sion of neurofilament and keratin proteins in cutaneous neu- roendocrine carcinoma cells. J Invest Dermatol 1986, 86:74. 12. Goesling W, McKee PH, Mayer RJ: Merkel cell carcinoma. J Clin Oncol 2002, 20(2):588-598. 13. Yiengpruksawan A, Coit DG, Thaler HT, Urmacher C, Knapper WK: Merkel cell carcinoma: prognosis and management. Arch Surg 1991, 126:1514-9. 14. Ott MJ, Tanabe KK, Gadd MA, Stark P, Smith BL, Finkelstein DM, Souba WW: Multimodality management of Merkel cell carcinoma. Arch Surg 1999, 134:388-93. 15. Rubsamen PE, Tanenbaum E, Grove AS, Gould E: Merkel cell carci- noma of the eyelid and the periocular tissues. Am J Ophthalmol 1992, 113:674-80. 16. Messina JL, Reintgen DS, Cruse CW, Rappaport DP, Berman C, Fen- ske NA, Glass LF: Selective lymphadenopathy in patients with Merkel cell cutaneous neuroendocrine carcinoma. Ann Surg Oncol 1997, 4:389-95. 17. Fening E, Brenner B, Katz A, Rakovsky E, Hana MB, Sulkes A: The role of radiation therapy and chemotherapy in the treat- ment of Merkel cell carcinoma. Cancer 1997, 80:881-85. 18. Barnerji R, Byrd CJ: Update in the biology of chronic lym- phocytic leukemia. Curr Opin Oncol 2000, 12:22-9. 19. Levi F, Randimbison L, Te V-C, La Vecchia C: Non Hodgkin's lym- phomas, chronic lymphocytic leukemias and skin cancers. Br J Cancer 1996, 74:1847-1850. 20. Keating MJ: Chronic Lymphocytic Leukemia. Semin Oncol 1999, 26(5 Suppl 14):107-14. 21. Faguet GB: Chronic Lymphocytic Leukemia: an updated review. J Clin Oncol 1994, 12(9):1974-90. 22. Adami J, Frisch M, Yuen J, Glimelius B, Melbye M: Evidence of an association between non-Hodgkin's lymphoma and skin cancer. BMJ 1995, 310:1491-5. 23. Brenner B, Sulkes A, Rakowsky E, Feinmesser M, Yukelson A, Bar- Haim E, Katz A, Idelevich E, Neuman A, Barhana M, Fenig E: Second neoplasm in patients with Merkel cell carcinoma. Cancer 2001, 91:1358-62. 24. Ziprin P, Smith S, Salerno G, Rosin RD: Two cases of Merkel cell tumor arising in patients with chronic lymphocytic leukaemia. Br J Dermatol 2000, 142:525-28. 25. Gillenwater AM, Hessel AC, Morrison WH, Burgess M, Silva EG, Rob- erts D, Goepfert H: Merkel cell carcinoma of the head and neck: Effect of surgical excision and radiation on recurrence and survival. Arch Otolaryngol Head Neck Surg 2001, 127:149-154. 26. Brown TJ, Brooke AJ, Macfarlane DF, Goldberg LH: Merkel cell car- cinoma: spontaneous resolution and management of meta- static disease. Dermatol Surg 1999, 25:23-5. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/5/106/pre pub Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." 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