Ceylan et al. Journal of Medical Case Reports 2012, 6:339 http://www.jmedicalcasereports.com/content/6/1/339 only taken medical treatment due to collagen tissue ill- ness for 15 years. Subsequently, she was accepted to our clinic for surgery and open complex cyst removal was done under general anesthesia. The kidney was sutured watertight. However, in the postoperative period, a ur- eteral double j stent was placed because the drainage did not stop in the following 3-week duration. Because drainage of 250cc daily continued without any decrease the week following the double j stent placement, intra- venous pyelography (IVP) was applied and urinary leak- age was found (Figure 1). Urinary drainage was more prominent at night than during the day (250 versus 50cc). Subsequently, oral desmopressin was started at a dosage of 0.2mg/day in order to decrease the nocturnal urinary drainage; no abnormal situation was observed in serum electrolytes (specifically hyponatremia). The patient’s drainage decreased dramatically to a daily total of 50cc and she was discharged on the fifth day of the medical treatment after the drainage had stopped. After 1 week when the patient came for follow-up, the desmo- pressin treatment was ended. IVP was applied 3 weeks after the patient was discharged, and a urogram showed that the two kidneys were active and the double j stent Page 2 of 3 was removed because no urinary leakage was observed (Figure 2). Discussion Desmopressin is a drug which has been used as a syn- thetic arginine vasopressin analog for 40 years. This drug has been proved to be effective for the treatment of noc- turnal enuresis, central diabetes insipidus and some coa- gulopathies. The antidiuresis induced by desmopressin is more potent than that of arginine vasopressin, resulting in an increased urine osmolality and decreased urine output. Several investigators have demonstrated signifi- cant decreases in nocturnal diuresis and subsequent improvements in sleep [4-7]. In the study of Razzaghi et al. nasal desmopressin (MinirinW) was applied to 7 out of 15 patients and 8 of them were observed without taking any treatment. Urinary leakage duration reduced significantly in the group who had desmopressin (MinirinW) treatment. They observed a dramatic decrease in urine leakage in the group to whom MinirinW was given. They found this result to be statistically significant [8]. Furthermore, Çimentepe et al. reported on a patient Figure 1 A view of urinary leakage in intravenous pyelography. Figure 2 A view of the improved urinary leakage in intravenous pyelography after oral desmopressin therapy.