Amoureux et al. BMC Cancer 2010, 10:91 http://www.biomedcentral.com/1471-2407/10/91 48. Hildebrandt H, Becker C, Glüer S, Rösner H, Gerardy-Schahn R, Rahmann H: Polysialic acid on the neural cell adhesion molecule correlates with expression of polysialyltransferases and promotes neuroblastoma cell growth. Cancer Res 1998, 58:779-784. 49. Fukuda S, Kondo T, Takebayashi H, Taga T: Negative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocytic differentiation pathway. Cell Death Differ 2004, 11:196-202. 50. Hack MA, Sugimori M, Lundberg C, Nakafuku M, Götz M: Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6. Mol Cell Neurosci 2004, 25:664-678. 51. Mahal LK, Charter NW, Angata K, Fukuda M, Koshland DE Jr, Bertozzi CR: A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells. Science 2001, 294:380-381. Pre-publication history The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/10/91/prepub doi:10.1186/1471-2407-10-91 Cite this article as: Amoureux et al.: Polysialic Acid Neural Cell Adhesion Molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines. BMC Cancer 2010 10:91. Page 12 of 12 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color ﬁgure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit