|                                                                                                                                                             |
|-------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                                                                                                                                                             |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|                                                                                                                                                        |   | Three Months |  |   |   |   |   |   |   |   |   |   |   |
|                                                                                                                                                        |   |  Ended |  |   | Year Ended December 31, |
| (MILLIONS OF DOLLARS, EXCEPT RATIO)                                                                                                                         |   | March 30,2014 |  |   | 2013 |  |   | 2012 |  |   | 2011 |  |   | 2010 |  |   | 2009 |  |
|                                                                                                                                                        |   |   |   |   |   |   |   |   |   |   |   |   |
| Determination of Earnings:                                                                                                                                  |   |   |   |   |   |   |   |   |   |   |   |   |
| Income from continuing operations before provision for taxes on income, noncontrolling interests and cumulative effect of a change in accounting principles |   | $ | 2,847 |  |   | $ | 15,716 |  |   | $ | 11,242 |  |   | $ | 11,481 |  |   | $ | 8,846 |  |   | $ | 10,421 |  |
| Less:                                                                                                                                                       |   |   |   |   |   |   |   |   |   |   |   |   |
| Noncontrolling interests                                                                                                                                    |   | 13 |  |   | 44 |  |   | 47 |  |   | 60 |  |   | 46 |  |   | 15 |  |
| Income attributable to Pfizer Inc.                                                                                                                          |   | 2,834 |  |   | 15,672 |  |   | 11,195 |  |   | 11,421 |  |   | 8,800 |  |   | 10,406 |  |
| Add (deduct):                                                                                                                                               |   |   |   |   |   |   |   |   |   |   |   |   |
| Capitalized interest                                                                                                                                        |   | (10 | ) |   | (32 | ) |   | (41 | ) |   | (50 | ) |   | (36 | ) |   | (34 | ) |
| Amortization of capitalized interest                                                                                                                        |   | 10 |  |   | 65 |  |   | 69 |  |   | 95 |  |   | 29 |  |   | 29 |  |
| Equity (income)/loss from equity method investments                                                                                                         |   | (36 | ) |   | (55 | ) |   | (99 | ) |   | (82 | ) |   | (78 | ) |   | 4 |  |
| Distributed income of equity method investments                                                                                                             |   | — |  |   | 162 |  |   | 85 |  |   | 190 |  |   | 26 |  |   | — |  |
| Fixed charges                                                                                                                                               |   | 341 |  |   | 1,495 |  |   | 1,627 |  |   | 1,812 |  |   | 1,930 |  |   | 1,358 |  |
| Total earnings as defined                                                                                                                                   |   | $ | 3,139 |  |   | $ | 17,307 |  |   | $ | 12,836 |  |   | $ | 13,386 |  |   | $ | 10,671 |  |   | $ | 11,763 |  |
|                                                                                                                                                        |   |   |   |   |   |   |   |   |   |   |   |   |
| Fixed charges:                                                                                                                                              |   |   |   |   |   |   |   |   |   |   |   |   |
| Interest expense(a)                                                                                                                                         |   | $ | 321 |  |   | $ | 1,414 |  |   | $ | 1,522 |  |   | $ | 1,681 |  |   | $ | 1,797 |  |   | $ | 1,232 |  |
| Preferred stock dividends(b)                                                                                                                                |   | 1 |  |   | 3 |  |   | 4 |  |   | 5 |  |   | 6 |  |   | 7 |  |
| Rents(c)                                                                                                                                                    |   | 19 |  |   | 78 |  |   | 101 |  |   | 126 |  |   | 127 |  |   | 119 |  |
| Fixed charges                                                                                                                                               |   | 341 |  |   | 1,495 |  |   | 1,627 |  |   | 1,812 |  |   | 1,930 |  |   | 1,358 |  |
| Capitalized interest                                                                                                                                        |   | 10 |  |   | 32 |  |   | 41 |  |   | 50 |  |   | 36 |  |   | 34 |  |
| Total fixed charges                                                                                                                                         |   | $ | 351 |  |   | $ | 1,527 |  |   | $ | 1,668 |  |   | $ | 1,862 |  |   | $ | 1,966 |  |   | $ | 1,392 |  |
|                                                                                                                                                        |   |   |   |   |   |   |   |   |   |   |   |   |
| Ratio of earnings to fixed charges                                                                                                                          |   | 8.9 |  |   | 11.3 |  |   | 7.7 |  |   | 7.2 |  |   | 5.4 |  |   | 8.5 |  |

|           |                                                                                                                                                                                                                                                                                                                                                                                     |
|-----------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| (a)  | Interest expense includes amortization of debt premium, discount and other debt costs. Interest expense does not include interest related to uncertain tax positions of $43 million for the first three months of 2014; $222 million for the twelve months ended December 31, 2013; $265 million for 2012; $338 million for 2011; $389 million for 2010; and $337 million for 2009. |

|           |                                                                                                                                         |
|-----------|-----------------------------------------------------------------------------------------------------------------------------------------|
| (b)  | Preferred stock dividends related to our Series A convertible perpetual preferred stock held by an Employee Stock Ownership Plan Trust. |

|           |                                                                                                                                                                                       |
|-----------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| (c)  | Rents included in the computation consist of one-third of rental expense, which we believe to be a conservative estimate of an interest factor in our leases, which are not material. |