National Residue Program Quarterly Report (April-June 2022) 

National Residue Program 

In FY 2022 Q3, nine analytical methods were used by FSIS to detect approximately 260 different 

veterinary drugs, pesticides, and environmental contaminants. Key observations are below. 

Surveillance Sampling Plan 

Specified slaughter subclasses are sampled at the time of slaughter, after a carcass has passed 

antemortem inspection. Of the 1,994 samples analyzed by FSIS (1,914 from U.S. Federal plants and 80 

from U.S. State inspected plants), ten sample contained violative chemical residues. In total, more than 

361,000 chemical residue analyses were conducted on the 1,994 samples collected under the 

surveillance sampling plan. 

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Table 1: Summary of FY 2022 Q3 Surveillance Sampling Results 

FY 2022 Q3 summary of surveillance sampling results from FSIS inspector-collected muscle, kidney, and liver tissue from carcasses and parts is 

shown. 

Number of Samples Analyzed this Quarter Total Number of Animal Number of Non- Animal Class Samples Planned for FY Total Number of Non- Number of Category Violative Positives 2022 Samples 1 Detect Samples Violative Samples Samples 

Bovine 

Beef Cows 800 215 193 2 --

Bob Veal 400 80 78 -- 3 

Dairy Cows 800 196 202 -- 2 

Formula-Fed Veal 75 13 17 -- --

Heifers 400 119 107 -- 1 

Non-Formula-Fed Veal 75 9 15 -- --

Steers 400 112 105 -- --

Feral Swine 75 14 14 -- --

Porcine Market Swine 800 219 200 -- --

Roaster Swine 300 67 56 -- --

Sows 800 185 178 2 2 

Young Chickens 400 107 97 -- --

Poultry Whole Chickens 400 105 83 1 --

Young Turkeys 800 219 202 1 --

Goats 300 79 66 1 1 

Other 

Species 

Lambs 100 24 20 -- --

Mature Sheep 100 23 17 -- 1 

Siluriformes(Catfish) 650 148 144 -- --

Egg Products 400 43 40 -- --

Quarter Total 8,075 1,994 1,977 7 10 

1 For raw product, a sample is a representative portion of a meat, poultry, or egg product collected to identify potential microbiological, chemical, or 

pathological hazards. 

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Table 2: FY 2022 Q3 Number Collected NRP Surveillance Sampling Residues by Chemical Methods 

FY 2022 Q3 number collected surveillance sampling residue sampling summary is shown reflecting the number of samples (carcasses) analyzed 

per chemical method per animal class. 

Number of Samples Analyzed per Chemical Method 

Animal 

Category 

Animal 

Class Aminoglycosides Antifungal 

Dyes Carbadox Metals MRM1 Nitrofurans Pesticides PFAS2 Speciation 

Bovine 

Beef Cows 217 -- -- 19 217 -- 159 -- --

Bob Veal 83 -- -- 30 83 -- 60 -- --

Dairy Cows 198 -- -- 15 198 -- 147 -- --

Formula-Fed Veal 13 -- -- -- 13 -- 3 -- --

Heifers 120 -- -- 37 120 -- 82 -- --

Non- Formula Fed Veal 9 -- -- -- 9 -- 1 -- --

Steers 112 -- -- 35 112 -- 71 -- --

Feral Swine -- -- -- -- -- -- 14 11 --

Porcine Market Swine 219 -- -- 21 219 -- 166 48 --

Roaster Swine -- -- 67 -- -- -- -- -- --

Sows 189 -- -- 25 189 -- 134 36 --

Young Chickens 107 -- -- 29 107 19 57 48 --

Poultry Whole Chickens 106 -- -- -- 103 102 106 -- --

Young Turkeys 220 -- -- 45 218 54 110 -- --

Other 

Species 

Goats 81 -- -- -- 81 -- 14 -- --

Lambs 24 -- -- -- 24 -- 9 -- --

Mature Sheep 24 -- -- -- 24 -- 15 -- --

Siluriformes (Catfish) -- 92 -- 92 137 45 93 40 103 

Egg Products -- -- -- -- 43 -- 43 -- --

Quarter Total 1,722 92 67 348 1,897 220 1,284 183 103 1 MRM: multiresidue method 

2 PFAS: polyfluoroalkyl substances 

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Table 3. FY 2022 Q3 Surveillance Sampling Residue Violations 

List of FY 2022 Q3 surveillance sampling residue violations, including specific compound, concentration, tolerance, and regulatory citation by 

animal class is shown. 

Animal 

Class Tissue Compound Concentration Units Tolerance Level Value Authority (CFR Citation) 

Bob Veal 

Muscle 

Kidney 

Kidney 

Ketoprofen 

Gamithromycin 

Flunixin 

* 

* 

* 

* 

* 

* 

* 

* 

* 

Not Approved/1/ 

Not Approved/1/ 

Not Approved/1/ 

Muscle Salbutamol * * * Not Approved/1/ 

Dairy Cow 

Muscle Meloxicam * * * Not Approved/1/ 

Heifer Liver Ractopamine 176 ppb 90 40 CFR 556.570 

Sow Muscle Diclofenac * * * Not Approved/1/ 

Goat Muscle Moxidectin * * * Not Approved/1/ 

Mature Sheep Muscle Diclofenac * * * Not Approved/1/ 

* Violative residue results were detected but not quantified. 

/1/Not Approved: the residue detected is not approved in that tissue for the animal class. 

ppb – parts per billion (μg/kg) 

CFR – Code of Federal Regulations 

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Inspector-Generated Sampling Plan 

FSIS inspectors conduct inspector-generated sampling when they suspect that animals presented for 

slaughter may have violative levels of chemical residues. If an inspector suspects that there is misuse of 

drugs that cannot be detected by the KISTM test, the samples are sent directly to the laboratory for 

appropriate analysis. These samples are reported under the Inspector-Generated program. If an 

inspector suspects that there is misuse of drugs that cannot be detected by the KISTM test, the samples 

are sent directly to the laboratory for appropriate analysis. These samples are reported under the 

Collector-Generated program. 

In FY 2022 Q3, of the 32,880 Kidney Inhibition Swab (KISTM) tests conducted on animals selected by FSIS 

(Table 4), 470 samples were submitted to FSIS field laboratories for further analysis. In total, 98 chemical 

residue violations were reported in 75 samples (Table 5). Due to multiple analyses per sample 

submitted, multiple residue violations may be found in the same sample. The predominant violative 

residues in the inspector-generated samples were Desfuroylceftiofur (26), Flunixin (12), and penicillin 

(10) which account for 27%, 12%, and 10% of total violative residues, respectively. 

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Table 4. Summary of FY 2022 Q3 Inspector-Generated Sampling (KISTM) Test and Confirmatory Tests 

FY 2022 Q3 summary of KISTM tests, number of in-plant screens with negative results, number of carcasses sent to FSIS laboratory for 

confirmation, and the number of carcasses (i.e., samples) with violations for each animal class. 

KIS TM Test 

Animal Category Animal Class Total Number of 

In-plant 

Number of In-plant 

Negative 

Number of Samples 

Analyzed in FSIS 

Number of Samples 

with Confirmed Lab 

Carcasses Carcasses Labs Violations 

Bovine Beef Cows 2,513 2,456 55 11 

Bob Veal 3,983 3,955 26 14 

Bulls 305 297 8 2 

Dairy Cows 22,331 22,025 300 58 

Formula-fed Veal 54 54 -- --

Heavy Calves 44 44 -- --

Heifers 994 972 21 2 

Non-Formula-fed Veal 53 51 2 1 

Steers 1,885 1,850 33 2 

Boar/Stag Swine 32 31 1 --

Porcine Market Swine 3,373 3,350 22 --

Roaster Swine 346 346 -- --

Sows 1,569 1,563 6 1 

Adult Goats 23 23 -- --

Goats 135 134 1 1 

Other Species Young Goats 30 30 -- --

Mature Sheep 68 67 1 --

Lambs 198 197 1 --

Quarter Total 32,880 32,393 470 75 

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Table 5. FY 2022 Q3 Inspector-Generated Sampling Residue Violation Resultsby Chemical Residue and Animal Class 

FY 2022 Q3 summary of chemical residue violations reported within the inspector-generated sampling. 

Animal Class 

Chemical Residue 

Beef Cow Bob Veal Bulls Dairy Cow Heavy 

Calves Heifer 

NonFormulafed Veal 

Steer Sow Goat Quarter 

Total 

Ampicillin -- 1 -- 2 -- -- -- -- -- -- 3 

Ciprofloxacin -- 2 -- -- -- -- -- 1 -- -- 3 

Desethylene 

Ciprofloxacin -- 2 -- -- -- -- -- -- -- -- 2 

Desfuroylceftiofur 2 3 -- 18 -- 1 -- 2 -- -- 26 

Diclofenac -- 1 -- -- -- -- -- -- -- -- 1 

Doramectin 2 -- -- -- -- -- -- -- -- -- 2 

Enrofloxacin -- 2 -- -- -- -- -- -- -- -- 2 

Florfenicol 1 -- 2 1 -- -- -- 1 -- -- 5 

Flunixin 3 4 1 2 -- -- -- 2 -- -- 12 

Ketoprofen -- 1 -- -- -- -- -- -- -- -- 1 

Lincomycin -- -- -- 1 -- -- -- -- -- -- 1 

Meloxicam 1 -- -- -- -- -- -- -- -- -- 1 

Neomycin -- 2 -- 1 -- -- -- -- -- -- 3 

Norfloxacin -- -- -- -- -- -- 1 -- -- -- 1 

Oxyphenylbutazone 1 -- -- -- -- -- -- -- -- -- 1 

Oxytetracycline -- -- -- 2 -- -- -- -- -- 1 3 

Penicillin 1 -- -- 7 -- -- -- 2 -- -- 10 

Phenylbutazone 1 -- -- -- -- -- -- -- -- -- 1 

Sulfadimethoxine -- -- -- 5 -- -- -- -- -- -- 5 

Sulfamethazine -- -- -- 2 -- 1 -- 1 -- -- 4 

Sulfamethoxazole -- 2 -- -- -- -- -- -- -- -- 2 

7 
Sulfathiazole -- 2 -- -- -- -- -- -- -- -- 2 

Tildipirosin -- 1 -- -- -- -- -- -- -- -- 1 

Tilmicosin 3 -- 1 -- -- -- -- 1 -- -- 6 

Quarter Total 15 23 4 41 0 2 2 10 0 1 98 

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Table 6. Summary of FY 2022 Q3 Collected-Generated Sampling 

FY 2022 Q3 summary of suspect animal samples sent directly to FSIS laboratory (collected-generated sampling) for appropriate analysis. 

Number of Non- Number of Non-Detect Number of Violative Animal Category Animal Class Total Samples Violative Positives Samples Samples Samples 

Bovine 

Beef Cow 1 1 -- --

Dairy Cow 5 4 1 --

Bob Veal 3 2 -- 1 

Heifer 2 0 1 1 

Steer 30 26 4 --

Porcine Market Swine 16 16 -- --

Other Species Mature Sheep 1 1 -- --

Lamb 4 4 -- --

Quarter Total 62 54 6 2 

In addition to the publication of the FY 2022 Sampling Summary NRP results, FSIS posts the details of each positive non-violative, and positive 

violative residue result associated with the NRP sampling program in a spreadsheet format on the FSIS website at: 

https://www.fsis.usda.gov/wps/portal/fsis/topics/data-collection-and-reports/chemistry/red-books/redbook 

This spreadsheet includes detailed information regarding samples collected and analyzed by FSIS under both the “scheduled” sampling and the 

“inspector-generated” sampling programs. Overall, these data indicate levels of metals in FSIS-regulated product, on average, are relatively low 

and are not likely to cause a human health concern. FSIS plans to update this spreadsheet on an ongoing basis so as to increase program 

transparency for all stakeholders. The spreadsheet includes the following data fields: sample collection and reviewed date, the project code, the 

animal class, tissue type, chemical residue name, concentration values, sample results (whether positive non-violative or positive violative), 

chemical concentration values (if any) and the CFR reference for each chemical listed. 

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Import Residue Sampling 

Imported meat, poultry, and egg products are sampled through the point-of-entry Import Reinspection Sampling Plan. This verifies that foreign 

inspection systems in exporting countries are equivalent to U.S. standards. A total of 611 samples were analyzed under this program in FY 2022 

Q3. During FY 2022 Q3, there was one violative import sample. The results are summarized in Table 7. 

Table 7. Summary of FY 2022 Q3 Residue Sampling of Imported Products 

FY 2022 Q3 import residue samples by inspection level and production type. 

Normal Increased Intensified/1/ 

Code Method 

Number of 

Samples 

Analyzed 

Non-Violative 

Positives 

Samples 

Violative 

Positive 

Samples 

Number Nonof Violative 

Samples Positives 

Analyzed Samples 

Number 

of 

Samples 

Analyzed 

NonViolative 

Positive 

Samples 

Quarter Total 

Imported Fish ProductsEastern Laboratory Speciation 184 -- -- -- -- -- -- 184 

IMPFISH_CH_E 

Imported Fish ProductsWestern Laboratory 

IMPFISH_CH_W 

Nitrofurans, 

Pesticides 180 -- -- -- -- 3 -- 183 

Imported - Metals 

IMPMETALS Metals 64 -- -- 1 -- -- -- 65 

Imported - Pesticide 

IMPPESTICIDE Pesticides 134 1 1 -- -- 3 -- 137 

Imported Egg Products -

Chemistry Pesticides 11 -- -- -- -- -- -- 11 

IMPRESEGG 

Imported Processed 

Products - Residue Eastern Avermectins 15 -- -- 1 -- -- -- 16 

Lab IMPRESPR_EL 

Imported Processed 

Products - Residue 

Midwestern Lab Sulfonamides 15 -- -- -- -- -- -- 15 

IMPRESPR_MWL 

Quarter Total 603 1 1 2 0 6 0 611 

Product Name and Project Analytical 

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/1/Increased is a level of reinspection above the normal level that is directed by a FSIS management decision. Under increased reinspection, FSIS may hold, on a case-by-case basis, 

lots of imported meat, poultry, or egg products pending receipt of a laboratory analysis. If FSIS does not place the product on hold, the importer of record is still required to hold 

product tested for adulterants by FSIS and is not to allow such product to enter commerce unless and until negative results are received. Intensified is a level of reinspection that is 

implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified reinspection, FSIS holds the 

sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be held. Intensified is a level of 

reinspection that is implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified 

reinspection, FSIS holds the sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be 

held. 

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