<PAGE>
                          MARKETING SERVICE AGREEMENT

        THIS MARKETING SERVICE AGREEMENT (the "Marketing Agreement"), is made
this ____ day of March, 1999 (the "Effective Date"), by and between PREMIER
RESEARCH WORLDWIDE, LTD., a Delaware corporation with its principal place of
business located at 30 South 17th Street, Philadelphia, PA 19103 (referred to
herein as "PRWW") and AMERICA'S DOCTOR, INC., a Delaware corporation with its
principal place of business located at 11403 Cronridge Drive, Suite 200, Owings
Mills, MD 21117 (referred to herein as "AD").

        WHEREAS, PRWW and AD entered into a Stock Purchase Agreement, dated July
2, 1998, and a Support and Service Agreement on July 2, 1998, as amended from
time to time (the "Support and Service Agreement");

        WHEREAS, AD desires to market AD's services regarding obtaining subjects
for clinical trials for third parties, including contract research organizations
("CRO's") and pharmaceutical companies;

        WHEREAS, PRWW has specialized expertise in obtaining and marketing
subjects in clinical trials; and

        WHEREAS, AD acknowledges that PRWW's specialized expertise is not
readily available in the marketplace and will add great value to AD;

        WHEREAS, PRWW desires to assist AD in the marketing of AD's services to
such third parties by, among other things, providing AD with education and
training on how to obtain and market subjects for clinical trials;

        NOW THEREFORE, intending to be legally bound, the parties hereto agree
as follows:

1.     Recitals. The abovementioned recitals are incorporated as if fully set 
forth herein.

2.     Term. The term of this Marketing Agreement shall be deemed to have 
commenced on January l, 1999 (the "Effective Date") and expire on December 31, 
2000.

3.     PRWW Marketing Services. Whereas, AD desires to determine the commercial
feasibility of recruiting candidates for clinical trials and marketing said
candidates to pharmaceutical, biotechnology and medical device companies and
clinical/contract research organizations (CRO).

In consideration of AD's use of potential clinical trial candidate data supplied
to PRWW and for PRWW's services, as defined below, supplied in support of AD's
test of commercial feasibility, AD agrees to pay PRWW in accordance with the
amounts set forth in paragraph 4. 


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Within ninety days of expiration of this agreement, AD can elect to purchase
PRWW's exclusive right to patient data, as set forth in the Support and Service
Agreement, section 4, for an additional sum of $200,000 as specified in
paragraph 4.

3.1    Scope of Service. PRWW and specifically, the CEO of PRWW (or other
       officer(s) of PRWW mutually agreed upon by AD and PRWW), shall consult
       with and provide marketing services to the Board of Directors and the
       officers of AD, at reasonable times, concerning matters pertaining to the
       marketing of AD's services to CRO's and other third parties interested in
       recruitment, quantification and qualification of volunteers for
       clinical/medical studies (the "PRWW Marketing Services"). PRWW's
       Marketing Services to AD shall include, but not be limited to the
       following duties and functions: (i) educate and train AD officers,
       employees and representatives about volunteer and patient recruitment and
       marketing techniques for volunteer and patient recruitment; (ii) impart
       personal expertise and knowledge as to the workings of CRO and
       pharmaceutical organizations with regard to the recruitment,
       quantification and qualification of volunteers for clinical/medical
       studies; (iii) reasonably make available the resources of PRWW to AD's
       marketing efforts to other CRO's and pharmaceutical companies; (iv)
       accompany representatives of AD on marketing and sales presentations; (v)
       use its best efforts to introduce AD to CRO's and pharmaceutical
       companies; (vi) assist in determining appropriate pricing levels for AD's
       products and services; and (vii) any other marketing/sales related
       activities reasonably requested by AD or its Directors. PRWW's Marketing
       Services shall not be required to exceed two hundred (200) hours for each
       three (3) month calendar period under this Marketing Agreement. In
       addition, AD shall use its best efforts to provide PRWW with timely
       notification of when the PRWW Marketing Services will be required. PRWW
       and its representatives shall not represent AD, AD's Board of Directors,
       AD's officers or any other member of AD in any transaction or
       communication nor shall PRWW and its representatives make claim to do so,
       unless authorized by AD, its officers or its Directors.

       During the term of this agreement, Sections 4.1, 4.2, and 4.3 of the
       Support and Service Agreement shall be deleted in their entirety and
       replaced with the following:

       "4.1 AD may provide similar solicitation, quantification, recruitment or
       other services as those provided to PRWW pursuant to this Agreement to
       any other person or entity at AD's sole discretion.


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       4.2    AD may contract with other CRO's (or any other person or entity 
       with an interest in volunteer recruitment, solicitation or qualification)
       in any manner whatsoever, at AD's sole discretion, provided that AD does
       not materially interfere with the Services granted to PRWW. PRWW agrees
       that there is no material interference provided that PRWW has the right
       to solicit, quantify, qualify and recruit volunteers for its studies
       pursuant to Section 3.2 of the Support and Service Agreement as amended.
       Specifically, AD may provide the Services to PRWW while simultaneously
       providing the same or similar recruitment, quantification or
       qualification services to a third party, regardless of whether such same
       or similar services conflict in whole or in part with the provision of
       the Services to PRWW. For example, if AD has contracted with a CRO to
       provide recruits for a study that conflicts with either: (a) a study
       ongoing by PRWW; or (b) a study to be commenced by PRWW, in either case,
       AD shall provide both PRWW and the other CRO with the right to solicit,
       quantify and recruit patients simultaneously.

       4.3    All materials, documents, volunteer data, and other information
       provided to PRWW by AD during the course of this Agreement shall be
       deemed to be, between AD and PRWW, confidential information
       ("Information") which shall be owned by AD. Upon termination of this
       Agreement, PRWW may retain all Information provided to PRWW by AD
       pursuant to Section 3.1 hereunder provided that PRWW may only use such
       Information for the express purpose of recruitment of volunteers for
       studies in which PRWW participates and for which PRWW properly notified
       AD pursuant to Section 3.2 of the Agreement. During the Term of this
       Agreement PRWW may only use the Information for the express purpose of
       recruitment of volunteers for studies in which PRWW participates and for
       which PRWW properly notified AD pursuant to Section 3.2 of the Agreement.
       PRWW shall be liable for any unauthorized use or disclosure of the
       Information by PRWW's employees which could have reasonably been
       prevented by PRWW."


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4.     Fee. AD shall pay PRWW a total fee of Four Million Six Hundred Thousand
Dollars ($4,600,000) in installments of Five Hundred Seventy Five Thousand
Dollars ($575,000) per three (3) month calendar period (the "Fee") with an
additional $200,000 due upon AD's decision to purchase PRWW's exclusive right to
patient data. The payment schedule shall be as follows and there shall be a five
(5) day grace period for all payments:

       a.    $575,000 due on March 15, 1999 (for the three month period 
commencing January 1, 1999);
       b.    $575,000 due on June 15, 1999 (for the three month period 
commencing April 1, 1999);
       c.    $575,000 due on September 15, 1999 (for the three month period
commencing July 1, 1999);
       d.    $575,000 due on December 15, 1999 (for the three month period
commencing October 1, 1999);
       e.    $575,000 due on March 15, 2000 (for the three month period 
commencing January 1, 2000);
       f.    $575,000 due on June 15, 2000 (for the three month period 
commencing April 1, 2000);
       g.    $575,000 due on September 15, 2000 (for the three month period
commencing July 1, 2000);
       h.    $575,000 due on December 15, 2000 (for the three month period
commencing October 1, 2000).
       i.    $200,000 due on or before the expiration of this agreement, 
contingent upon AD decision to purchase PRWW's exclusive right to patient data.

5.     Relationship of the parties. The parties are independent contractors. 
Nothing in this Marketing Agreement or in the activities contemplated by the
parties pursuant to this Marketing Agreement shall be deemed to create an
agency, partnership, employment or joint venture relationship between the
parties. Each party shall be deemed to be acting solely on its own behalf and,
except as expressly stated, has no authority to pledge the credit of, or incur
obligations or perform any acts or make any statements on behalf of, the other
party. Neither party shall represent to any person or permit any person to act
upon the belief that it has any such authority from the other party. Neither
party's officers or employees, agents or contractors shall be deemed officers,
employees, agents or contractors of the other party for any purpose.





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6.     Information. In connection with this Marketing Agreement, AD and its 
Directors, officers and representatives will furnish PRWW and its
representatives with data, material and information concerning AD (the
"Information") which PRWW reasonably requests or is necessary for the
performance by PRWW hereunder. PRWW agrees that any Information received by PRWW
or its representatives during any furtherance of PRWW's obligations hereunder
will be treated by PRWW in full confidence and will not be revealed to any other
person, firm, organizations or entity except to PRWW's agents, employees, and
representatives in connection with the PRWW Marketing Services to be performed
on behalf of AD: (i) who will be informed of the confidential nature of the
Information; and (ii) who will treat such Information in full confidence and
shall not reveal any Information to any other person, firm, organization or
entity. PRWW shall be responsible for any breach of this provision by any of its
agents, employees or representatives.

7.     Termination. AD may terminate this agreement by giving one hundred eighty
(180) days written notice to PRWW. Upon AD's termination of this agreement, the
exclusive patient data revert back to PRWW pursuant to the Support and Service
Agreement between PRWW and AD, dated July 2, 1998,

8.     Termination for Cause/Liquidated Damages. In the event that AD fails to
make any or all payments due under Section 4 above within forty-five (45) days
of when such payment(s) is due, then PRWW may terminate this Marketing Agreement
for cause by notifying AD of such termination in writing. In the event this
Marketing Agreement is terminated by PRWW for cause as provided in this Section
8, AD shall pay liquidated damages to PRWW in an amount equal to the actual
amount due at the time of termination by PRWW plus and amount equal to the fees
which would have been earned over the next two calendar quarters.

9.     Trademarks. Nothing herein confers or shall confer upon PRWW any right, 
title or interest in any goodwill, trademark, trade name, service mark, brand
name, knowledge or credibility of AD. PRWW acknowledges that all such interests
are the exclusive property of AD. PRWW shall not utilize any goodwill,
trademark, service mark, trade name, brand name, knowledge or credibility of AD
without prior written consent of AD and shall not assert any claim of ownership
or right to same.







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10.    Indemnification. Each party hereto shall indemnify and hold the other 
party and its directors, officers, employees, agents, subsidiaries, parents,
affiliates, consultants and subcontractors (all "Associates") harmless from any
claim, liability, loss, damages or expense, together with all reasonable costs
and expenses relating thereto, including reasonable attorneys' fees, resulting
from the negligent, reckless or willful acts or omissions of such party or its
Associates in connection with the providing of the PRWW Marketing Services
hereunder. Each party hereto shall indemnify and hold the other party and its
directors, officers, employees, agents, subsidiaries, parents, affiliates,
consultants and subcontractors (all "Associates") harmless from any claim,
liability, loss, damages or expense, together with all reasonable costs and
expenses relating thereto, including reasonable attorneys' fees, arising out of
or resulting from any breach of any representation, warranty, covenant or
obligation of such party contained in this Marketing Agreement herein.

11.    Survival. The parties respective rights and obligations under Sections 4
("Fee"), 6 ("Information'), 8 ("Trademarks') and 9 ("Indemnification") shall
survive any expiration or termination of this Marketing Agreement.

12.    Representations by PRWW. PRWW represents, warrants, covenants and agrees
that the PRWW Marketing Services shall be furnished and in all respects provided
in conformance and compliance with applicable laws. PRWW represents and warrants
that it has the authority to enter into this Marketing Agreement and the right
to provide the PRWW Marketing Services to AD hereunder without breach of any
obligation to any other third party, and that its performance under this
Marketing Agreement will not breach any contract, agreement, rule, law or
regulation of whatever nature.

13.    Representations by AD. AD represents and warrants that it has the 
authority to enter into this Marketing Agreement without breach of any
obligation to any other third party, and that its performance under this
Marketing Agreement will not breach any contract, agreement, rule, law or
regulation of whatever nature.

14.    Entire Agreement/Amendments. This Marketing Agreement constitutes the 
entire agreement between the parties and supersedes and takes precedence over
all prior agreement or understandings, whether oral or written, between the
parties. This Marketing Agreement shall not be construed to govern any other
transactions between AD and PRWW. No changes, amendments or modifications of any
of the terms or conditions of this Agreement shall be valid unless made by an
instrument in writing signed by both parties.

15.    Assignment. Neither party shall assign any of its rights nor delegate 
any of its obligations under this Agreement without the prior written consent of
the other party; however, PRWW may assign its rights under this Agreement to any
successor to PRWW by merger or consolidation or any person or entity which
acquires substantially all of the assets and business of PRWW, which assignee
shall assume PRWW's duties and obligations hereunder.




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16.    Arbitration. Any controversy or claim arising out of or relating to this
Marketing Agreement, or the breach thereof, shall be settled by arbitration in
accordance of the rules of the American Arbitration Association, and judgment
upon the award rendered by the arbitrator(s) shall be entered in any court
having jurisdiction thereof. For that purpose, the parties hereto consent to the
jurisdiction and venue of an appropriate court located in the State of Maryland.
The parties acknowledge that in no event shall the aggregate contribution of the
other party, its agents, members, employees, and affiliates of each,
collectively exceed the amount of the Fee provided in Section 4 of this
Marketing Agreement.

17.    Miscellaneous.

       17.1    This Marketing Agreement shall be governed by and construed in
accordance with the laws of the State of Maryland without regard to conflict of
law principles.

       17.2    Section heading are included for convenience only and are not to
be used to construe or interpret this Agreement.

       17.3    Whenever this Marketing Agreement requires either party's 
approval, consent or satisfaction, the response shall not be unreasonably or
arbitrarily withheld or delayed.

       17.4    The failure of either party to object to, or to take affirmative
action with respect to, any conduct of the other party that violates any term or
condition of this Marketing Agreement shall be limited to that particular
instance, and shall not be construed as a waiver of that party's right for such
breach or as a waiver of such remedies for future breaches by the other party.

       17.5    If any provision of this Marketing Agreement becomes unlawful or
unenforceable in any jurisdiction, such provision shall be ineffective only to
the extent of such invalidity or enforceability without invalidating the
remaining provisions of this Marketing Agreement, and any such invalidity or
unenforceability in any jurisdiction shall not invalidate such provision or
render it unenforceable in any other jurisdiction.

       17.6    This Marketing Agreement may be executed by the parties in one or
more counterparts; each of which when so executed shall be an original, but all
such counterparts shall constitute one and the same instrument.

       17.7    All pronouns and words shall be read in appropriate number and
gender; the masculine, feminine and neuter shall be interpreted interchangeably;
and the singular shall include the plural and vice versa, as the circumstances
may require.




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       17.8    The parties hereto represent that they have carefully read the
foregoing Marketing Agreement, understood its terms, had the opportunity to
consult with an attorney of their choice, and voluntarily signed the same as
their own free act with the intent to be legally bound thereby. The parties
acknowledge that the normal rule of construction to the effect that any
ambiguities are to be resolved against the drafting party shall not be employed
in the interpretation of this Agreement or any amendments hereto. The terms of
this Marketing Agreement are contractual and not a mere recital.

       17.9    Notices and other communications shall be transmitted in writing
by certified U.S. Mail, postage prepaid, return receipt requested or by
overnight courier, addressed to the parties at the address first set forth
above. Such notices and communications shall be deemed effective four (4) days
after the date of mailing or upon receipt as evidenced by the U.S. Postal
Service return receipt cards, whichever is earlier, or upon receipt if sent by
overnight courier.



                             (CONTINUED NEXT PAGE)





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        IN WITNESS WHEREOF, the parties hereto have caused this Marketing
Agreement to be duly executed as of the date first above-written, such parties
acting by their representatives being thereunto duly authorized.



PREMIER RESEARCH WORLDWIDE, LTD.




--------------------------------
By: Joel Morganroth, CEO



AMERICA'S DOCTOR, INC.



/s/ Scott M. Rifkin
---------------------------------
By: Scott M. Rifkin, CEO