National Residue Program Quarterly Report (July-September 2022) 

National Residue Program 

In FY 2022 Q4, nine analytical methods were used by FSIS to detect approximately 260 different 

veterinary drugs, pesticides, and environmental contaminants. Key observations are below. 

Surveillance Sampling Plan 

Specified slaughter subclasses are sampled at the time of slaughter, after a carcass has passed 

antemortem inspection. Of the 1,940 samples analyzed by FSIS (1,876 from U.S. Federal plants and 64 

from U.S. State inspected plants), eight sample contained violative chemical residues. In total, more 

than 361,000 chemical residue analyses were conducted on the 1,940 samples collected under the 

surveillance sampling plan. 

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Table 1: Summary of FY 2022 Q4 Surveillance Sampling Results 

FY 2022 Q4 summary of surveillance sampling results from FSIS inspector-collected muscle, kidney, and liver tissue from carcasses and parts is 

shown. 

Number of Samples Analyzed this Quarter Total Number of Animal Number of Non- Animal Class Samples Planned for FY Total Number of Non- Number of Category Violative Positives 2022 Samples 1 Detect Samples Violative Samples Samples 

Bovine 

Beef Cows 800 229 223 5 1 

Bob Veal 400 95 94 1 --

Dairy Cows 800 202 200 1 1 

Formula-Fed Veal 75 23 23 -- --

Heifers 400 99 99 -- --

Non-Formula-Fed Veal 75 10 10 -- --

Steers 400 102 101 -- 1 

Feral Swine 75 8 8 -- --

Porcine Market Swine 800 216 214 2 --

Roaster Swine 300 78 75 -- 3 

Sows 800 194 193 1 --

Young Chickens 400 101 101 -- --

Poultry Whole Chickens 400 85 84 1 --

Young Turkeys 800 204 203 1 --

Goats 300 74 73 1 --

Other 

Species 

Lambs 100 25 25 -- --

Mature Sheep 100 21 21 -- --

Siluriformes(Catfish) 650 131 129 -- 2 

Egg Products 400 43 43 -- --

Quarter Total 8,075 1,940 1919 13 8 

1 For raw product, a sample is a representative portion of a meat, poultry, or egg product collected to identify potential microbiological, chemical, or 

pathological hazards. 

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Table 2: FY 2022 Q4 Number Collected NRP Surveillance Sampling Residues by Chemical Methods 

FY 2022 Q4 number collected surveillance sampling residue sampling summary is shown reflecting the number of samples (carcasses) analyzed 

per chemical method per animal class. 

Number of Samples Analyzed per Chemical Method 

Animal 

Category 

Animal 

Class Aminoglycosides Antifungal 

Dyes Carbadox Metals MRM1 Nitrofurans Pesticides PFAS2 Speciation 

Bovine 

Beef Cows 229 -- -- 43 229 -- 167 -- --

Bob Veal 95 -- -- 43 95 -- 73 -- --

Dairy Cows 202 -- -- 37 202 -- 156 -- --

Formula-Fed Veal 23 -- -- 1 23 -- 5 -- --

Heifers 99 -- -- 28 99 -- 68 -- --

Non- Formula Fed Veal 10 -- -- -- 10 -- 1 -- --

Steers 102 -- -- 34 102 -- 69 -- --

Feral Swine -- -- -- -- -- -- 8 -- --

Porcine Market Swine 216 -- -- 41 216 -- 166 8 --

Roaster Swine -- -- 78 -- -- -- -- -- --

Sows 194 -- -- 42 194 -- 140 3 --

Young Chickens 101 -- -- 49 101 17 48 31 --

Poultry Whole Chickens 85 -- -- -- 85 85 85 -- --

Young Turkeys 204 -- -- 67 204 39 100 -- --

Other 

Species 

Goats 74 -- -- -- 74 -- 19 -- --

Lambs 25 -- -- -- 25 -- 14 -- --

Mature Sheep 21 -- -- -- 21 -- 11 -- --

Siluriformes (Catfish) -- 111 -- 111 123 12 72 15 119 

Egg Products -- -- -- -- 43 -- 43 -- --

Quarter Total 1,680 111 78 496 1,846 153 1,245 57 119 1 MRM: multiresidue method 

2 PFAS: polyfluoroalkyl substances 

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Table 3. FY 2022 Q4 Surveillance Sampling Residue Violations 

List of FY 2022 Q4 surveillance sampling residue violations, including specific compound, concentration, tolerance, and regulatory citation by 

animal class is shown. 

Animal 

Class Tissue Compound Concentration Units Tolerance Level Value Authority (CFR Citation) 

Beef Cow 

Liver 

Muscle 

Sulfadimethoxine 

Sulfadimethoxine 

0.795 

0.686 

ppm 

ppm 

0.1 ppm 

0.1 ppm 

40 CFR 556.640 

40 CFR 556.640 

Dairy Cow 

Steer 

Liver 

Muscle 

Flunixin 

Diclofenac 

0.331 

* 

ppm 

* 

0.125 ppm 

* 

40 CFR 556.286 

Not Approved/1/ 

Liver Carbadox 52.5 ppb 30 40 CFR 556.100 

Roaster Swine Liver Carbadox 43.6 ppb 30 40 CFR 556.100 

Liver Carbadox 71.8 ppb 30 40 CFR 556.100 

Muscle Metolachlor * * * Not Approved/1/ 

Siluriformes Fish 

Muscle Metolachlor * * * Not Approved/1/ 

* Violative residue results were detected but not quantified. 

/1/Not Approved: the residue detected is not approved in that tissue for the animal class. 

ppm – parts per million (mg/kg) 

ppb – parts per billion (μg/kg) 

CFR – Code of Federal Regulations 

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Inspector-Generated Sampling Plan 

FSIS inspectors conduct inspector-generated sampling when they suspect that animals presented for 

slaughter may have violative levels of chemical residues. If an inspector suspects that there is misuse of 

drugs that cannot be detected by the KISTM test, the samples are sent directly to the laboratory for 

appropriate analysis. These samples are reported under the Inspector-Generated program. If an 

inspector suspects that there is misuse of drugs that cannot be detected by the KISTM test, the samples 

are sent directly to the laboratory for appropriate analysis. These samples are reported under the 

Collector-Generated program. 

In FY 2022 Q4, of the 31,772 Kidney Inhibition Swab (KISTM) tests conducted on animals selected by FSIS 

(Table 4), 439 samples were submitted to FSIS field laboratories for further analysis. In total, 93 chemical 

residue violations were reported in 71 samples (Table 5). Due to multiple analyses per sample 

submitted, multiple residue violations may be found in the same sample. The predominant violative 

residues in the inspector-generated samples were Desfuroylceftiofur(26), Flunixin (11), and Neomycin 

(8) which account for 28%, 12%, and 9% of total violative residues, respectively. 

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Table 4. Summary of FY 2022 Q4 Inspector-Generated Sampling (KISTM) Test and Confirmatory Tests 

FY 2022 Q4 summary of KISTM tests, number of in-plant screens with negative results, number of carcasses sent to FSIS laboratory for 

confirmation, and the number of carcasses (i.e., samples) with violations for each animal class. 

KIS TM Test 

Animal Category Animal Class Total Number of 

In-plant 

Number of In-plant 

Negative 

Number of Samples 

Analyzed in FSIS 

Number of Samples 

with Confirmed Lab 

Carcasses Carcasses Labs Violations 

Bovine Beef Cows 2,248 2,185 48 5 

Bob Veal 3,765 3,734 26 11 

Bulls 378 350 21 3 

Dairy Cows 17,640 17,350 227 44 

Formula-fed Veal 14 14 -- --

Heavy Calves 33 33 -- --

Heifers 654 635 18 1 

Non-Formula-fed Veal 12 10 2 1 

Steers 1,566 1,499 56 3 

Boar/Stag Swine 23 23 -- --

Porcine Market Swine 2,842 2,813 21 1 

Roaster Swine 323 313 8 --

Sows 1,707 1,691 9 2 

Adult Goats 24 24 -- --

Goats 25 25 -- --

Other Species Young Goats 55 55 -- --

Mature Sheep 81 81 -- --

Lambs 382 377 3 --

Quarter Total 31,772 31,212 439 71 

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Table 5. FY 2022 Q4 Inspector-Generated Sampling Residue Violation Resultsby Chemical Residue and Animal Class 

FY 2022 Q4 summary of chemical residue violations reported within the inspector-generated sampling. 

Animal Class 

Chemical Residue 

Beef Cow Bob Veal Bulls Dairy Cow Heavy 

Calves Heifer 

NonFormulafed Veal 

Steer Market 

Swine Sow Quarter Total 

Ampicillin -- -- -- 2 -- -- -- -- -- -- 2 

Ciprofloxacin -- 2 -- 2 -- -- -- -- -- -- 4 

Desethylene 

Ciprofloxacin -- 2 -- -- -- -- -- -- -- -- 2 

Desfuroylceftiofur 4 1 1 19 -- -- -- 1 -- -- 26 

Dihydrostreptomycin -- -- -- 2 -- -- -- -- -- -- 2 

Enrofloxacin -- 2 -- -- -- -- -- -- -- -- 2 

Florfenicol 1 1 -- 1 -- -- -- -- -- -- 3 

Florfenicol Amine -- 1 -- -- -- -- -- -- -- -- 1 

Flunixin -- 1 -- 8 -- -- 1 1 -- -- 11 

Gentamycin Sulfate -- -- -- -- -- 1 -- -- -- -- 1 

Meloxicam -- 1 -- 4 -- -- -- 1 -- -- 6 

Neomycin -- 4 -- 3 -- -- 1 -- -- -- 8 

Oxyphenylbutazone -- -- -- -- -- -- -- -- 1 -- 1 

Penicillin -- -- 1 4 -- -- -- -- -- 1 6 

Phenylbutazone -- -- -- -- -- -- -- -- 1 -- 1 

Spectinomycin -- 2 -- -- -- -- -- -- -- -- 2 

Sulfadimethoxine -- -- -- 3 -- -- -- -- -- -- 3 

Sulfadoxine -- -- -- -- -- -- -- -- -- 1 1 

Sulfamethazine -- -- 1 -- -- -- -- -- -- 1 2 

Sulfamethoxazole -- 3 -- -- -- -- -- -- -- -- 3 

Sulfathiazole -- 3 -- -- -- -- -- -- -- -- 3 

7 
Tilmicosin -- 1 -- 1 -- -- -- 1 -- -- 3 

Quarter Total 5 24 3 49 0 1 2 4 2 3 93 

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Table 6. Summary of FY 2022 Q4 Collected-Generated Sampling 

FY 2022 Q4 summary of suspect animal samples sent directly to FSIS laboratory (collected-generated sampling) for appropriate analysis. 

Number of Non- Number of Non-Detect Number of Violative Animal Category Animal Class Total Samples Violative Positives Samples Samples Samples 

Bovine 

Beef Cow 8 6 2 --

Bob Veal 1 -- 1 --

Bulls 3 3 -- --

Dairy Cows 11 9 1 1 

Heifer 11 11 -- --

Steer 222 214 5 3 

Porcine Market Swine 142 137 2 3 

Roaster Swine 1 1 -- --

Goat 4 4 -- --

Other Species Young Goat 3 3 -- --

Mature Sheep 4 4 -- --

Lamb 43 42 -- 1 

Quarter Total 453 434 11 8 

In addition to the publication of the quarterly FY 2022 Sampling Summary NRP results, FSIS posts the details of each positive non-violative, and 

positive violative residue result associated with the NRP sampling program in a spreadsheet format on the FSIS Residue Chemistry website. 

This spreadsheet includes detailed information regarding samples collected and analyzed by FSIS under both the “scheduled” sampling and the 

“inspector-generated” sampling programs. Overall, these data indicate levels of metals in FSIS-regulated product, on average, are relatively low 

and are not likely to cause a human health concern. FSIS plans to update this spreadsheet on an ongoing basis so as to increase program 

transparency for all stakeholders. The spreadsheet includes the following data fields: sample collection and reviewed date, the project code, the 

animal class, tissue type, chemical residue name, concentration values, sample results (whether positive non-violative or positive violative), 

chemical concentration values (if any) and the CFR reference for each chemical listed. 

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Import Residue Sampling 

Imported meat, poultry, and egg products are sampled through the point-of-entry Import Reinspection Sampling Plan. This verifies that foreign 

inspection systems in exporting countries are equivalent to U.S. standards. A total of 263 samples were analyzed under this program in FY 2022 

Q4. During FY 2022 Q4, there were zero violative import samples. The results are summarized in Table 7. 

Table 7. Summary of FY 2022 Q4 Residue Sampling of Imported Products 

FY 2022 Q4 import residue samples by inspection level and production type. 

Normal Intensified/1/ 

Product Name and Project 

Code 

Analytical 

Method 

Number of 

Samples 

Analyzed 

Non-Violative 

Positives 

Samples 

Violative 

Positive 

Samples 

Number 

of 

Samples 

Analyzed 

NonViolative 

Positive 

Samples 

Quarter Total 

Imported Fish ProductsEastern Laboratory Speciation 34 -- -- -- -- 34 

IMPFISH_CH_E 

Imported Fish ProductsWestern Laboratory 

IMPFISH_CH_W 

Nitrofurans, 

Pesticides 27 -- -- -- -- 27 

Imported - Metals 

IMPMETALS Metals 54 -- -- -- -- 54 

Imported - Pesticide 

IMPPESTICIDE Pesticides 75 -- -- 14 -- 89 

Imported Egg Products -

Chemistry Pesticides 11 -- -- -- -- 11 

IMPRESEGG 

Imported Processed 

Products - Residue Eastern Avermectins 22 -- -- -- -- 22 

Lab IMPRESPR_EL 

Imported Processed 

Products - Residue 

Midwestern Lab Sulfonamides 26 -- -- -- -- 26 

IMPRESPR_MWL 

Quarter Total 263 0 0 14 0 611 

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/1/Increased is a level of reinspection above the normal level that is directed by a FSIS management decision. Under increased reinspection, FSIS may hold, on a case-by-case basis, 

lots of imported meat, poultry, or egg products pending receipt of a laboratory analysis. If FSIS does not place the product on hold, the importer of record is still required to hold 

product tested for adulterants by FSIS and is not to allow such product to enter commerce unless and until negative results are received. Intensified is a level of reinspection that is 

implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified reinspection, FSIS holds the 

sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be held. Intensified is a level of 

reinspection that is implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified 

reinspection, FSIS holds the sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be 

held. 

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