National Residue Program Quarterly Report (Jan-March 2022) 

National Residue Program 

In FY 2022 Q2, nine analytical methods were used by FSIS to detect approximately 260 different 

veterinary drugs, pesticides, and environmental contaminants. Key observations are below. 

Surveillance Sampling Plan 

Specified slaughter subclasses are sampled at the time of slaughter, after a carcass has passed 

antemortem inspection. Of the 1,856 samples analyzed by FSIS (1,763 from U.S. Federal plants and 93 

from U.S. State inspected plants), six sample contained violative chemical residues. In total, more than 

361,000 chemical residue analyses were conducted on the 1,856 samples collected under the 

surveillance sampling plan. 

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Table 1: Summary of FY 2022 Q2 Surveillance Sampling Results 

FY 2022 Q2 summary of surveillance sampling results from FSIS inspector-collected muscle, kidney, and liver tissue from carcasses and parts is 

shown. 

Number of Samples Analyzed this Quarter Total Number of Animal Number of Non- Animal Class Samples Planned for FY Total Number of Non- Number of Category Violative Positives 2022 Samples 1 Detect Samples Violative Samples Samples 

Bovine 

Beef Cows 800 196 193 3 0 

Bob Veal 400 80 78 2 0 

Dairy Cows 800 204 202 1 1 

Formula-Fed Veal 75 17 17 0 0 

Heifers 400 108 107 1 0 

Non-Formula-Fed Veal 75 15 15 0 0 

Steers 400 106 105 0 1 

Feral Swine 75 14 14 0 0 

Porcine Market Swine 800 201 200 1 0 

Roaster Swine 300 56 56 0 0 

Sows 800 178 178 0 0 

Young Chickens 400 97 97 0 0 

Poultry Whole Chickens 400 83 83 0 0 

Young Turkeys 800 202 202 0 0 

Goats 300 68 66 1 1 

Other 

Species 

Lambs 100 20 20 0 0 

Mature Sheep 100 18 17 1 0 

Siluriformes(Catfish) 650 153 144 6 3 

Egg Products 400 40 40 0 0 

Quarter Total 8,075 1,856 1,834 16 6 

1 For raw product, a sample is a representative portion of a meat, poultry, or egg product collected to identify potential microbiological, chemical, or 

pathological hazards. 

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Table 2: FY 2022 Q2 Number Collected NRP Surveillance Sampling Residues by Chemical Methods 

FY 2022 Q2 number collected surveillance sampling residue sampling summary is shown reflecting the number of samples (carcasses) analyzed 

per chemical method per animal class. 

Number of Samples Analyzed per Chemical Method 

Animal 

Category 

Animal 

Class Aminoglycosides Antifungal 

Dyes Carbadox Metals MRM1 Nitrofurans Pesticides PFAS2 Speciation 

Bovine 

Beef Cows 196 -- -- 49 196 -- 115 -- --

Bob Veal 80 -- -- 18 80 -- 43 -- --

Dairy Cows 204 -- -- 39 204 -- 113 -- --

Formula-Fed Veal 17 -- -- 2 17 -- 3 -- --

Heifers 108 -- -- 30 108 -- 61 -- --

Non- Formula Fed Veal 15 -- -- -- 15 -- 4 -- --

Steers 106 -- -- 38 106 -- 58 -- --

Feral Swine -- -- -- -- -- 14 10 --

Porcine Market Swine 201 -- -- 53 201 -- 107 20 --

Roaster Swine -- 56 -- -- -- -- --

Sows 178 -- -- 37 178 -- 90 19 --

Young Chickens 97 -- -- 23 97 17 54 11 --

Poultry Whole Chickens 83 -- -- -- 83 83 83 -- --

Young Turkeys 202 -- -- 31 202 57 118 -- --

Other 

Species 

Goats 68 -- -- -- 68 -- 24 -- --

Lambs 20 -- -- -- 19 -- 9 -- --

Mature Sheep 18 -- -- -- 18 -- 8 -- --

Siluriformes (Catfish) -- 29 -- 29 142 114 123 14 39 

Egg Products -- -- -- -- 36 -- 40 -- --

Quarter Total 1,593 29 56 349 1,770 271 1067 140 39 1 MRM: multiresidue method 2 PFAS: polyfluoroalkyl substances 

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Table 3. FY 2022 Q2 Surveillance Sampling Residue Violations 

List of FY 2022 Q2 surveillance sampling residue violations, including specific compound, concentration, tolerance, and regulatory citation by 

animal class is shown. 

Animal 

Class Tissue Compound Concentration Units Tolerance Level Value Authority (CFR Citation) 

Dairy Cow 

Goat 

Siluriformes

Steer 

Liver 

Muscle 

Muscle 

Muscle 

Muscle 

Muscle 

Muscle 

Florfenicol 

Florfenicol 

Moxidectin 

Diclofenac 

Metolachlor 

Nitrofurazone 

Diclofenac 

4.37 

0.400 

* 

* 

* 

* 

* 

ppm 

ppm 

* 

* 

* 

* 

* 

3.7 

0.3 

* 

* 

* 

* 

* 

40 CFR 556.283 

40 CFR 556.283 

Not Approved/1/ 

Not Approved/1/ 

Not Approved/1/ 

Not Approved/1/ 

Not Approved/1/ 

* Violative residue results were detected but not quantified. 

/1/Not Approved: the residue detected is not approved for the animal class. 

ppm – parts per million (mg/kg) 

CFR – Code of Federal Regulations 

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Inspector-Generated Sampling Plan 

FSIS inspectors conduct inspector-generated sampling when they suspect that animals presented for 

slaughter may have violative levels of chemical residues. If an inspector suspects that there is misuse of 

drugs that cannot be detected by the KISTM test, the samples are sent directly to the laboratory for 

appropriate analysis. These samples are reported under the Inspector-Generated program. If an 

inspector suspects that there is misuse of drugs that cannot be detected by the KISTM test, the samples 

are sent directly to the laboratory for appropriate analysis. These samples are reported under the 

Collector-Generated program. 

In FY 2022 Q2, of the 37,883 Kidney Inhibition Swab (KISTM) tests conducted on animals selected by FSIS 

(Table 4), 477 samples were submitted to FSIS field laboratories for further analysis. In total, 102 

chemical residue violations were reported in 92 samples (Table 5). Due to multiple analyses per sample 

submitted, multiple residue violations may be found in the same sample. The predominant violative 

residues in the inspector-generated samples were Desfuroylceftiofur (34) and penicillin (16) which 

account for 33% and 16% of total violative residues, respectively. 

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Table 4. Summary of FY 2022 Q2 Inspector-Generated Sampling (KISTM) Test and Confirmatory Tests 

FY 2022 Q2 summary of KISTM tests, number of in-plant screens with negative results, number of carcasses sent to FSIS laboratory for 

confirmation, and the number of carcasses (i.e., samples) with violations for each animal class. 

KIS TM Test 

Animal Category Animal Class Total Number of 

In-plant 

Number of In-plant 

Negative 

Number of Samples 

Analyzed in FSIS 

Number of Samples 

with Confirmed Lab 

Carcasses Carcasses Labs Violations 

Bovine Beef Cows 2,513 2,456 55 11 

Bob Veal 3,983 3,955 26 14 

Bulls 305 297 8 2 

Dairy Cows 22,331 22,025 300 58 

Formula-fed Veal 54 54 -- --

Heavy Calves 44 44 -- --

Heifers 994 972 21 2 

Non-Formula-fed Veal 53 51 2 1 

Steers 1,885 1,850 33 2 

Boar/Stag Swine 32 31 1 --

Porcine Market Swine 3,373 3,350 22 --

Roaster Swine 346 346 -- --

Sows 1,569 1,563 6 1 

Goats 135 134 1 1 

Other Species Mature Sheep 68 67 1 --

Lambs 198 197 1 --

Quarter Total 37,883 37,392 477 92 

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Table 5. FY 2022 Q2 Inspector-Generated Sampling Residue Violation Resultsby Chemical Residue and Animal Class 

FY 2022 Q2 summary of chemical residue violations reported within the inspector-generated sampling. 

Animal Class 

Chemical Residue 

Beef Cow Bob Veal Bulls Dairy Cow Heavy 

Calves Heifer 

NonFormulafed Veal 

Steer Sow Goat Quarter 

Total 

Ampicillin -- -- -- 2 -- -- -- -- -- -- 2 

Ciprofloxacin -- 1 -- 1 -- -- -- -- -- -- 2 

Desfuroylceftiofur 2 4 1 25 -- 1 -- 1 -- -- 34 

Dihydrostreptomycin -- -- -- 2 -- -- -- -- -- -- 2 

Doramectin 2 -- -- -- -- -- -- -- -- -- 2 

Florfenicol 1 -- -- 1 -- 1 1 -- -- -- 4 

Flunixin 1 2 -- 8 -- -- -- -- -- -- 11 

Gentamycin Sulfate -- -- 1 -- -- -- -- -- -- -- 1 

Meloxicam -- -- -- 1 -- -- -- -- -- -- 1 

Neomycin -- 4 -- 1 -- -- -- -- -- -- 5 

Oxytetracycline -- -- -- -- -- -- -- -- -- 1 1 

Penicillin 2 2 -- 11 -- -- -- -- 1 -- 16 

Sulfadimethoxine -- -- -- 10 -- -- -- -- -- -- 10 

Sulfamethazine -- -- -- 2 -- -- -- 1 -- -- 3 

Sulfamethoxazole -- 1 -- -- -- -- -- -- -- -- 1 

Sulfathiazole -- 1 -- -- -- -- -- -- -- -- 1 

Tilmicosin 5 1 -- -- -- -- -- -- -- -- 6 

Quarter Total 13 16 2 64 0 2 1 2 1 1 102 

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Table 6. Summary of FY 2022 Q2 Collected-Generated Sampling 

FY 2022 Q2 summary of suspect animal samples sent directly to FSIS laboratory (collected-generated sampling) for appropriate analysis. 

Number of Non- Number of Non-Detect Number of Violative Animal Category Animal Class Total Samples Violative Positives Samples Samples Samples 

Bovine 

Beef Cow 2 2 -- --

Bulls 1 -- 1 --

Dairy Cow 2 2 -- --

Formula-fed Veal 1 1 -- --

Heifer 3 3 -- --

Steer 11 6 3 2 

Porcine Market Swine 7 7 -- --

Other Species Goats 2 2 -- --

Lamb 3 3 -- --

Quarter Total 32 26 4 2 

In addition to the publication of the FY 2022 Sampling Summary NRP results, FSIS posts the details of each positive non-violative, and positive 

violative residue result associated with the NRP sampling program in a spreadsheet format on the FSIS website at: 

https://www.fsis.usda.gov/wps/portal/fsis/topics/data-collection-and-reports/chemistry/red-books/redbook 

This spreadsheet includes detailed information regarding samples collected and analyzed by FSIS under both the “scheduled” sampling and the 

“inspector-generated” sampling programs. Overall, these data indicate levels of metals in FSIS-regulated product, on average, are relatively low 

and are not likely to cause a human health concern. FSIS plans to update this spreadsheet on an ongoing basis so as to increase program 

transparency for all stakeholders. The spreadsheet includes the following data fields: sample collection and reviewed date, the project code, the 

animal class, tissue type, chemical residue name, concentration values, sample results (whether positive non-violative or positive violative), 

chemical concentration values (if any) and the CFR reference for each chemical listed. 

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Import Residue Sampling 

Imported meat, poultry, and egg products are sampled through the point-of-entry Import Reinspection Sampling Plan. This verifies that foreign 

inspection systems in exporting countries are equivalent to U.S. standards. A total of 768 samples were analyzed under this program in FY 2022 

Q2. During FY 2022 Q2, there were no violative import samples. The results are summarized in Table 7. 

Table 7. Summary of FY 2022 Q2 Residue Sampling of Imported Products 

FY 2022 Q2 import residue samples by inspection level and production type. 

Normal Intensified/1/ 

Analytical Number of Non-Violative Number of Non-Violative Product Name and Project Code Method Samples Positives Samples Positive Quarter Total 

Analyzed Samples Analyzed Samples 

Imported Fish Products-Eastern Laboratory 

IMPFISH_CH_E 

Antifungal Dyes, 

Metals, MRM 218 -- -- -- 218 

Imported Fish Products-Western Laboratory 

IMPFISH_CH_W 

Nitrofurans, 

Pesticides 217 -- 1 -- 218 

Imported - Metals 

IMPMETALS Metals 102 -- -- -- 102 

Imported - Pesticide 

IMPPESTICIDE Pesticides 189 1 -- -- 189 

Imported Egg Products - Chemistry 

IMPRESEGG Pesticides 6 -- -- -- 6 

Imported Processed Products - Residue 

Eastern Lab IMPRESPR_EL Avermectins 16 -- -- -- 16 

Imported Processed Products - Residue 

Midwestern Lab IMPRESPR_MWL Sulfonamides 19 -- -- -- 19 

Quarter Total 7687 1 1 0 768 

/1/Increased is a level of reinspection above the normal level that is directed by a FSIS management decision. Under increased reinspection, FSIS may hold, on a case-by-case basis, 

lots of imported meat, poultry, or egg products pending receipt of a laboratory analysis. If FSIS does not place the product on hold, the importer of record is still required to hold 

product tested for adulterants by FSIS and is not to allow such product to enter commerce unless and until negative results are received. Intensified is a level of reinspection that is 

implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified reinspection, FSIS holds the 

sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be held. Intensified is a level of 

reinspection that is implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified 

reinspection, FSIS holds the sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be 

held. 

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