|UNITED STATES
            SECURITIES AND EXCHANGE COMMISSIONWashington, D.C. 20549                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
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|SCHEDULE 13G
          UNDER THE SECURITIES
            AND EXCHANGE COMMISSION
          (AMENDMENT NO.
            1)*                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
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|Aastrom Biosciences, Inc.
          (Name of Issuer)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
|Common Stock, No Par Value
            
            (Title of Class of Securities)
          00253U107(CUSIP Number)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
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|February 25, 2001
          (Date of Event Which Requires Filing of this Statement)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
|Check the appropriate box to designate the
          rule pursuant to which this Schedule is filed:
        [   ]  Rule 13d-1 (b)
            [x ]  Rule 13d-1 (c)
            [   ]  Rule 13d-1(d)
        * The remainder of this cover page shall
          be filled out for a reporting person's initial filing on this form with
          respect to the subject class of securities, and for any subsequent amendment
          containing information which would alter the disclosures provided in
          a prior cover page.
        The information required in the remainder
          of this cover page shall not be deemed to be "filed" for the
          purpose of Section 18 of the Securities Exchange Act of 1934 ("Act")
          or otherwise subject to the liabilities of that section of the Act but
          shall be subject to all other provisions of the Act (however, see the
          Notes).

|CUSIP NO. 00253U107
        ______________________________________________________________________________1.   NAMES OF REPORTING PERSONSI.R.S.
          IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
        Pfizer
          Inc.  
                         13-5315170
          _____________________________________________________________________ 2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF
          A GROUP (SEE INSTRUCTIONS)       
          (a)______  
                       
           (b)__________________________________________________________________________
           
           3.      SEC USE ONLY
        _____________________________________________________________________
           
           4.     CITIZENSHIP OR PLACE OF ORGANIZATIONDelaware
        _________________________________________________________
           
                                               5. SOLE
          VOTING POWER  
                                                  
       0
          
          NUMBER OF  _________________________________________________________
             
           SHARES                    6.
          SHARED VOTING POWER  
          BENEFICIALLY                        0 OWNED BY      _______________________________________________________ EACH                    7.
          SOLE DISPOSITIVE POWER REPORTING                            0 PERSON         _______________________________________________________ WITH                    8.
          SHARED DISPOSITIVE POWER_____________________________________________________________________9.       AGGREGATE
          AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON0
          _____________________________________________________________________10.      CHECK
          IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAINSHARES
          (SEE INSTRUCTIONS) _____0_____________________________________________________________________11.       PERCENT
          OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                               0%
          _____________________________________________________________________
          12.          TYPE
          OF REPORTING PERSON (SEE INSTRUCTIONS)
                                               CO
          _______________________________________________________________________________ITEM 1.(a)  Name of Issuer:
                    Aastrom Biosciences, Inc.
            (b)  Address of Issuer's Principal
              Executive Offices:
                     24 Frank Lloyd Wright DriveP. O. Box 376
                Ann Arbor, MI 48106
        ITEM 2.
        (a)   Name of Person Filing:
                      Pfizer Inc.
                
              (b)   Address of Principal Business Office or, if none ,
              Residence235
              East 42nd StreetNew
              York, NY 10017(c)    Citizenship:Delaware(d)    Title of Class
              of Securities:Common
              Stock, No Par Value(e)    CUSIP Number:00253U107
        ITEM 3.
        I F
          THIS STATEMENT IS FILED PURSUANT TO RULE 13d-1 (b) OR RULE 13d-2 b)  OR
          (c),                CHECK
          WHETHER THE PERSON FILING IS A:
        Not
          applicable
        ITEM 4.  OWNERSHIP
        (a)    Amount beneficially
              owned:   0(b)    Percent of
              class:  0(c)    Number of
              shares as to which the person has:
            (i)    Sole
              power to vote or to direct the vote:  0
            (ii)
                Shared power to vote or to direct the vote:  0
            (iii)  Sole
              power to dispose or to direct the disposition of: 0
            (iv)  Shared
              power to dispose or to direct the disposition of: 0
        ITEM 5.  OWNERSHIP OF FIVE PERCENT OR
          LESS OF A CLASS
        If this statement is being filed to report
              the fact that as of the date hereof the reporting person has ceased
              to be the beneficial owner of more than five percent of the class
              of securities, check the following [x].
        ITEM 6.   OWNERSHIP OF MORE THAN
          FIVE PERCENT ON BEHALF OF ANOTHER PERSON
        Not applicable
        ITEM 7.    IDENTIFICATION AND CLASSIFICATION
          OF THE SUBSIDIARY WHICH ACQUIRED THE              
                       
           SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY
        Not applicable
        ITEM 8.    IDENTIFICATION
          AND CLASSIFICATION OF MEMBERS OF THE GROUP
        Not
          applicable
        ITEM 9.    NOTICE OF DISSOLUTION
          OF GROUP
        Not applicable
        ITEM 10.  CERTIFICATIONS
        Not
          applicable
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|SIGNATURE
        After
          reasonable inquiry and to the best of my knowledge and belief, I certify
          that the information set forth in this statement is true, complete and
          correct.
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| | PFIZER INC.                                                                                                                                                        
| | -------------------------------------------------------------------------------------------------------------------------------------------------------------------
| | Date: January 3, 2000
         
        By:/s/ MARGARET
          M. FORAN Name: Margaret M. Foran
          Title: Vice President
          - Corporate Governance