National Residue Program Quarterly Report (October-December 2022) 

National Residue Program 

In FY 2023 Q1, nine analytical methods were used by FSIS to detect approximately 260 different 

veterinary drugs, pesticides, and environmental contaminants. Accompanying this report is an Excel 

spreadsheet. This sheet includes detailed information regarding samples taken by FSIS in both the 

residue domestic scheduled and inspector-generated sampling programs, in addition to the residue 

import sampling program results. Additionally, the excel sheet includes quarterly metals and per- and 

polyfluorinated alkyl substances (PFAS) results. Key observations are below. 

Surveillance Sampling Plan 

Specified slaughter subclasses are sampled at the time of slaughter, after a carcass has passed 

antemortem inspection. Of the 1,880 samples analyzed by FSIS (1,784 from U.S. Federal plants and 96 

from U.S. State inspected plants), six sample contained violative chemical residues. In total, more than 

361,000 chemical residue analyses were conducted on the 1,880 samples collected under the 

surveillance sampling plan. 

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Table 1: Summary of FY 2023 Q1 Surveillance Sampling Results 

FY 2023 Q1 summary of surveillance sampling results from FSIS inspector-collected muscle, kidney, and liver tissue from carcasses and parts is 

shown. 

Number of Samples Analyzed this Quarter Total Number of Animal Number of Non- Animal Class Samples Planned for FY Total Number of Non- Number of Category Violative Positives 2023 Samples 1 Detect Samples Violative Samples Samples 

Bovine 

Beef Cows 800 228 226 -- 2 

Bob Veal 400 102 100 -- 2 

Dairy Cows 800 205 203 2 --

Formula-Fed Veal 75 25 25 -- --

Heifers 400 119 119 -- --

Non-Formula-Fed Veal 75 14 14 -- --

Steers 400 113 113 -- --

Feral Swine 75 25 25 -- --

Porcine Market Swine 800 234 232 2 --

Roaster Swine 300 90 90 -- --

Sows 800 215 214 1 --

Poultry Young Chickens 400 110 110 -- --

Young Turkeys 400 102 102 -- --

Goats 300 74 73 -- 1 

Other 

Species 

Lambs 100 22 22 -- --

Sheep 100 25 25 -- --

Siluriformes(Catfish) 200 129 128 -- 1 

Egg Products 400 48 47 1 --

Quarter Total 6,825 1,880 1,868 6 6 

1 For raw product, a sample is a representative portionof a meat, poultry, or egg product collected to identify potential microbiological, chemical, or 

pathological hazards. 

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Table 2: FY 2023 Q1 Number Collected NRP Surveillance Sampling Residues by Chemical Methods 

FY 2023 Q1 number collected surveillance sampling residue sampling summary is shown reflecting the number of samples (carcasses) analyzed 

per chemical method per animal class. 

Number of Samples Analyzed per Chemical Method 

Animal 

Category 

Animal 

Class Aminoglycosides Antifungal 

Dyes Carbadox Metals MRM1 Nitrofurans Pesticides PFAS2 Speciation 

Bovine 

Beef Cows 228 -- -- 36 228 -- 162 -- --

Bob Veal 102 -- -- 28 102 -- 88 -- --

Dairy Cows 205 -- -- 43 205 -- 141 -- --

Formula-Fed Veal 25 -- -- 1 25 -- 10 -- --

Heifers 119 -- -- 32 119 -- 87 -- --

Non- Formula Fed Veal 14 -- -- -- 14 -- 1 -- --

Steers 113 -- -- 34 113 -- 80 -- --

Feral Swine -- -- -- -- -- -- 25 21 --

Porcine Market Swine 234 -- -- 45 234 -- 185 35 --

Roaster Swine -- -- 90 -- -- -- -- -- --

Sows 215 -- -- 32 215 -- 164 38 --

Poultry Young Chickens 110 -- -- 32 110 5 44 48 --

Young Turkeys 102 -- -- 28 102 6 55 -- --

Other 

Species 

Goats 74 -- -- -- 74 -- 23 -- --

Lambs 22 -- -- -- 22 -- 18 -- --

Mature Sheep 25 -- -- -- 25 -- 18 -- --

Siluriformes (Catfish) -- 128 -- 128 129 1 83 25 3 

Egg Products -- -- -- -- 48 -- 44 -- --

Quarter Total 1,588 128 90 439 1,765 12 1,228 167 3 1 MRM: multiresidue method 

2 PFAS: polyfluoroalkyl substances 

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Table 3. FY 2023 Q1 Surveillance Sampling Residue Violations 

List of FY 2023 Q1 surveillance sampling residue violations, including specific compound, concentration, tolerance, and regulatory citation by 

animal class is shown. 

Animal 

Class Tissue Compound Concentration Units Tolerance Level Value Authority (CFR Citation) 

Beef Cow 

Bob Veal 

Goat 

Liver 

Liver 

Muscle 

Kidney 

Muscle 

Muscle 

Muscle 

Sulfadimethoxine 

Sulfadimethoxine 

Sulfanilamide 

Penicillin 

Penicillin 

Gamithromycin 

Piperonyl Butoxide 

0.465 

11.0 

* 

1.22 

0.061 

* 

0.228 

ppm 

ppm 

* 

ppm 

ppm 

* 

ppm 

0.1 ppm 

0.1 ppm 

* 

0.05 ppm 

0.05 ppm 

0.15 ppm 

0.1 ppm 

40 CFR 556.640 

40 CFR 556.640 

Not Approved/1/ 

40 CFR 556.510 

40 CFR 556.510 

40 CFR 556.292 

40 CFR 180.127 

Muscle Simazine 0.0134 ppm * Not Approved/1/ 

Siluriformes Fish 

Muscle Simazine * * * Not Approved/1/ 

* Violative residue results were detected but not quantified. 

/1/Not Approved: the residue detected is not approved in that tissue for the animal class. 

ppm – parts per million (mg/kg) 

ppb – parts per billion (μg/kg) 

CFR – Code of Federal Regulations 

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Inspector-Generated Sampling Plan 

FSIS inspectors conduct inspector-generated sampling when they suspect that animals presented for 

slaughter may have violative levels of chemical residues. If an inspector suspects that there is misuse of 

drugs that cannot be detected by the KISTM test, the samples are sent directly to the laboratory for 

appropriate analysis. These samples are reported under the Inspector-Generated program. If an 

inspector suspects that there is misuse of drugs that cannot be detected by the KISTM test, the samples 

are sent directly to the laboratory for appropriate analysis. These samples are reported under the 

Collector-Generated program. 

In FY 2023 Q1, of the 30,126 Kidney Inhibition Swab (KISTM) tests conducted on animals selected by FSIS 

(Table 4), 390 samples were submitted to FSIS field laboratories for further analysis. In total, 118 

chemical residue violations were reported in 93 samples (Table 5). Due to multiple analyses per sample 

submitted, multiple residue violations may be found in the same sample. The predominant violative 

residues in the inspector-generated samples were Desfuroylceftiofur (32), Flunixin (14), and Neomycin 

(13) which account for 27%, 12%, and 11% of total violative residues, respectively. 

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Table 4. Summary of FY 2023 Q1 Inspector-Generated Sampling (KISTM) Test and Confirmatory Tests 

FY 2023 Q1 summary of KISTM tests, number of in-plant screens with negative results, number of carcasses sent to FSIS laboratory for 

confirmation, and the number of carcasses (i.e., samples) with violations for each animal class. 

KIS TM Test 

Animal Category Animal Class Total Number of 

In-plant 

Number of In-plant 

Negative 

Number of Samples 

Analyzed in FSIS 

Number of Samples 

with Confirmed Lab 

Carcasses Carcasses Labs Violations 

Bovine 

Bison 1 1 -- --

Beef Cows 2772 2713 44 12 

Bob Veal 3330 3277 45 25 

Bulls 382 365 14 4 

Dairy Cows 17096 16811 196 39 

Formula-fed Veal 17 15 1 --

Heavy Calves 51 48 3 1 

Heifers 664 645 18 2 

Non-Formula-fed Veal 162 144 17 6 

Steers 1402 1360 33 4 

Boar/Stag Swine 20 20 -- --

Porcine Market Swine 2566 2545 16 --

Roaster Swine 398 397 1 --

Sows 1030 1028 1 --

Adult Goats 19 19 -- --

Other Species Young Goats 28 28 -- --

Mature Sheep 49 49 -- --

Lambs 139 137 1 --

Quarter Total 30,126 29,602 390 93 

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Table 5. FY 2023 Q1 Inspector-Generated Sampling Residue Violation Resultsby Chemical Residue and Animal Class 

FY 2023 Q1 summary of chemical residue violations reported within the inspector-generated sampling. 

Chemical Residue Beef Cow Bob Veal Bulls Dairy Cow Heavy 

Calves Heifer 

NonFormulafed Veal 

Steer Market 

Swine 

Quarter 

Total 

Ciprofloxacin -- -- -- -- -- -- -- 1 -- 1 

Desfuroylceftiofur 2 1 -- 24 -- 2 -- 3 -- 32 

Dihydrostreptomycin -- -- -- 1 -- -- -- -- -- 1 

Doramectin 5 -- -- -- -- -- -- -- -- 5 

Eprinomectin -- -- -- -- -- -- -- -- 1 1 

Florfenicol 1 2 1 -- 1 -- 2 -- -- 7 

Florfenicol Amine -- 2 -- -- -- -- -- -- -- 2 

Flunixin 1 4 -- 8 -- -- -- 1 -- 14 

Gentamycin Sulfate -- -- -- -- -- -- -- -- 1 1 

Meloxicam -- -- -- 1 -- -- -- -- -- 1 

Neomycin -- 13 -- -- -- -- -- -- -- 13 

Oxytetracycline -- 1 -- 1 -- -- -- -- -- 2 

Penicillin 2 2 -- 6 -- -- -- -- -- 10 

Spectinomycin -- 3 -- -- -- -- -- -- -- 3 

Sulfadimethoxine -- -- -- 2 -- -- -- -- -- 2 

Sulfamethazine 1 3 1 1 1 -- -- -- -- 7 

Sulfamethoxazole -- 3 -- -- -- -- -- -- -- 3 

Sulfathiazole -- 2 -- -- -- -- -- -- -- 2 

Tilmicosin -- -- 3 -- -- -- 4 1 -- 8 

Tylosin 1 1 -- -- -- -- 1 -- -- 3 

Quarter Total 13 37 5 44 2 2 7 6 2 118 

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Table 6. Summary of FY 2023 Q1 Collected-Generated Sampling 

FY 2023 Q1 summary of suspect animal samples sent directly to FSIS laboratory (collected-generated sampling) for appropriate analysis. 

Number of Non- Number of Non-Detect Number of Violative Animal Category Animal Class Total Samples Violative Positives Samples Samples Samples 

Bovine 

Beef Cow 13 12 1 --

Dairy Cows 9 9 -- --

Formula-fed Veal 1 0 1 --

Steer 15 14 1 --

Porcine Market Swine 5 5 -- --

Poultry Young Chicken 1 1 -- --

Other Young Goat 1 1 -- --

Lamb 5 5 -- --

Quarter Total 50 47 3 0 

In addition to the publication of the quarterly FY 2023 Sampling Summary NRP results, FSIS posts the details of each positive non-violative, and 

positive violative residue result associated with the NRP sampling program in a spreadsheet format on the FSIS Residue Chemistry website. 

This spreadsheet includes detailed information regarding samples collected and analyzed by FSIS under both the “scheduled” sampling and the 

“inspector-generated” sampling programs. Overall, these data indicate levels of metals in FSIS-regulated product, on average, are relatively low 

and are not likely to cause a human health concern. FSIS plans to update this spreadsheet on an ongoing basis so as to increase program 

transparency for all stakeholders. The spreadsheet includes the following data fields: sample collection and reviewed date, the project code, the 

animal class, tissue type, chemical residue name, concentration values, sample results (whether positive non-violative or positive violative), 

chemical concentration values (if any) and the CFR reference for each chemical listed. 

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Import Residue Sampling 

Imported meat, poultry, and egg products are sampled through the point-of-entry Import Reinspection Sampling Plan. This verifies that foreign 

inspection systems in exporting countries are equivalent to U.S. standards. A total of 191 samples were analyzed under this program in FY 2022 

Q4. During FY 2022 Q4, there were zero violative import samples. The results are summarized in Table 7. 

Table 7. Summary of FY 2023 Q1 Residue Sampling of Imported Products 

FY 2023 Q1 import residue samples by inspection level and production type. 

Normal Intensified/1/ 

Product Name and Project 

Code 

Analytical 

Method 

Number of 

Samples 

Analyzed 

Non-Violative 

Positives 

Samples 

Violative 

Positive 

Samples 

Number of Non-Violative 

Samples Analyzed Positive Samples Quarter 

Total 

Imported - Metals 

IMPMETALS Metals 53 -- -- -- -- 53 

Imported - Pesticide 

IMPPESTICIDE Pesticides 110 -- -- 3 -- 113 

Imported Egg Products -

Chemistry Pesticides 10 -- -- -- -- 10 

IMPRESEGG 

Imported Processed 

Products - Residue Eastern Avermectins 6 -- -- -- -- 6 

Lab IMPRESPR_EL 

Imported Processed 

Products - Residue 

Midwestern Lab Sulfonamides 9 -- -- -- -- 9 

IMPRESPR_MWL 

Quarter Total 188 0 0 3 0 191 

/1/Increased is a level of reinspection above the normal level that is directed by a FSIS management decision. Under increased reinspection, FSIS may hold, on a case-by-case basis, 

lots of imported meat, poultry, or egg products pending receipt of a laboratory analysis. If FSIS does not place the product on hold, the importer of record is still required to hold 

product tested for adulterants by FSIS and is not to allow such product to enter commerce unless and until negative results are received. Intensified is a level of reinspection that is 

implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified reinspection, FSIS holds the 

sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be held. Intensified is a level of 

reinspection that is implemented automatically by the Public Health Information System (PHIS) when a Type of Inspection PHIS task is reported as “Fail.” Under intensified 

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reinspection, FSIS holds the sampled lot at the official import inspection establishment pending receipt of laboratory analysis. The sampled lot is not allowed to move off-site to be 

held. 

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